| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Miller, P A Chmielewsk. The regulation of high-affinity choline uptake in vitro in rat cortical and hippocampal synaptosomes by beta-carbolines administered in vivo. Neuroscience letters. vol 114. issue 3. 1990-10-24. PMID:2402344. |
the effects of several beta-carboline derivatives on sodium-dependent high-affinity choline uptake (hacu) were investigated in rat hippocampus and cerebral cortex. |
1990-10-24 |
2023-08-11 |
rat |
| V Luine, M Hearn. Spatial memory deficits in aged rats: contributions of the cholinergic system assessed by ChAT. Brain research. vol 523. issue 2. 1990-10-23. PMID:2400918. |
activity of choline acetylase (chat) was measured in basal forebrain cholinergic nuclei and in projection sites of these cells in the hippocampus and cortex of young rats and of aged rats who showed impaired performance on the radial arm maze. |
1990-10-23 |
2023-08-11 |
rat |
| B J Morley, L L Garne. AF64A depletes hippocampal high-affinity choline uptake but does not alter the density of alpha-bungarotoxin binding sites or modify the effect of exogenous choline. Brain research. vol 519. issue 1-2. 1990-10-16. PMID:2397397. |
af64a depletes hippocampal high-affinity choline uptake but does not alter the density of alpha-bungarotoxin binding sites or modify the effect of exogenous choline. |
1990-10-16 |
2023-08-11 |
Not clear |
| B J Morley, L L Garne. AF64A depletes hippocampal high-affinity choline uptake but does not alter the density of alpha-bungarotoxin binding sites or modify the effect of exogenous choline. Brain research. vol 519. issue 1-2. 1990-10-16. PMID:2397397. |
sodium-dependent, high-affinity choline uptake (hacu) and the density of alpha-bungarotoxin (butx) receptor-binding sites were measured in the hippocampus following the intraventricular infusion of ethylcholine aziridinium ion (af64a), a neurotoxin that competes with choline at high-affinity choline transport sites and may result in the degeneration of cholinergic axons. |
1990-10-16 |
2023-08-11 |
Not clear |
| C Messier, T Durkin, O Mrabet, C Destrad. Memory-improving action of glucose: indirect evidence for a facilitation of hippocampal acetylcholine synthesis. Behavioural brain research. vol 39. issue 2. 1990-10-02. PMID:2390197. |
the effect of a 3 g/kg glucose injection on the velocity of the sodium-dependent high-affinity choline uptake mechanism in the hippocampus was both measured in quiet control mice and in mice immediately after training in an operant bar pressing task. |
1990-10-02 |
2023-08-11 |
mouse |
| C Messier, T Durkin, O Mrabet, C Destrad. Memory-improving action of glucose: indirect evidence for a facilitation of hippocampal acetylcholine synthesis. Behavioural brain research. vol 39. issue 2. 1990-10-02. PMID:2390197. |
high-affinity choline uptake in the hippocampus was increased by training in the operant bar pressing task. |
1990-10-02 |
2023-08-11 |
mouse |
| D F Emerich, T J Wals. Cholinergic cell loss and cognitive impairments following intraventricular or intradentate injection of colchicine. Brain research. vol 517. issue 1-2. 1990-09-05. PMID:2375986. |
colchicine decreased choline acetyltransferase (chat) activity and high affinity choline uptake (hachu) in the hippocampus at 1 and 3, but not 9, weeks following surgery. |
1990-09-05 |
2023-08-11 |
rat |
| G E Meredith, F G Wouterloo. Hippocampal and midline thalamic fibers and terminals in relation to the choline acetyltransferase-immunoreactive neurons in nucleus accumbens of the rat: a light and electron microscopic study. The Journal of comparative neurology. vol 296. issue 2. 1990-07-31. PMID:2358532. |
hippocampal and midline thalamic fibers and terminals in relation to the choline acetyltransferase-immunoreactive neurons in nucleus accumbens of the rat: a light and electron microscopic study. |
1990-07-31 |
2023-08-11 |
rat |
| G E Meredith, F G Wouterloo. Hippocampal and midline thalamic fibers and terminals in relation to the choline acetyltransferase-immunoreactive neurons in nucleus accumbens of the rat: a light and electron microscopic study. The Journal of comparative neurology. vol 296. issue 2. 1990-07-31. PMID:2358532. |
no hippocampal endings were seen to contact the somata or primary dendrites of the choline acetyltransferase-immunoreactive neurons; however, three were found in synaptic contact with distal, immunolabelled dendritic shafts. |
1990-07-31 |
2023-08-11 |
rat |
| K Toide, T Arim. Effects of cholinergic drugs on extracellular levels of acetylcholine and choline in rat cortex, hippocampus and striatum studied by brain dialysis. European journal of pharmacology. vol 173. issue 2-3. 1990-04-12. PMID:2625133. |
effects of cholinergic drugs on extracellular levels of acetylcholine and choline in rat cortex, hippocampus and striatum studied by brain dialysis. |
1990-04-12 |
2023-08-11 |
rat |
| K Toide, T Arim. Effects of cholinergic drugs on extracellular levels of acetylcholine and choline in rat cortex, hippocampus and striatum studied by brain dialysis. European journal of pharmacology. vol 173. issue 2-3. 1990-04-12. PMID:2625133. |
induced no significant ach release in these three regions, probably due to the presence of highly concentrated physostigmine in the perfusate, while it induced an increase of the choline levels in both frontal cortex and hippocampus but not in corpus striatum. |
1990-04-12 |
2023-08-11 |
rat |
| A Marighetto, T Durkin, A Toumane, C Lebrun, R Jaffar. Septal alpha-noradrenergic antagonism in vivo blocks the testing-induced activation of septo-hippocampal cholinergic neurones and produces a concomitant deficit in working memory performance of mice. Pharmacology, biochemistry, and behavior. vol 34. issue 3. 1990-03-26. PMID:2560206. |
neurochemical analysis was performed using measures of the kinetics of sodium-dependent high-affinity choline uptake in samples of hippocampus from injected mice and their relevant controls in both quiet conditions and immediately following selective working memory testing in an 8-arm radial maze. |
1990-03-26 |
2023-08-11 |
mouse |
| A Represa, Y Ben-Ar. Effects of colchicine treatment on the cholinergic septohippocampal system. EXS. vol 57. 1990-03-15. PMID:2533099. |
in the septal region the number of choline acetyl transferase positive cells was significantly lower (by 23%) ipsilaterally to the colchicine injection as compared to the contralateral side; when the hippocampus is almost completely destroyed by colchicine treatment this cell loss is more important (by over 50%). |
1990-03-15 |
2023-08-11 |
Not clear |
| U Schindle. Pre-clinical evaluation of cognition enhancing drugs. Progress in neuro-psychopharmacology & biological psychiatry. vol 13 Suppl. 1990-03-12. PMID:2694232. |
they increase high-affinity choline uptake, and antagonize scopolamine- and ecs-induced decreases in acetylcholine concentrations in the hippocampus. |
1990-03-12 |
2023-08-11 |
Not clear |
| W H Meck, R A Smith, C L William. Organizational changes in cholinergic activity and enhanced visuospatial memory as a function of choline administered prenatally or postnatally or both. Behavioral neuroscience. vol 103. issue 6. 1990-03-08. PMID:2610916. |
the data demonstrate that perinatal choline supplementation causes (a) long-term facilitative effects on working and reference memory components of a 12-arm radial maze task, and (b) alternations of muscarinic receptor density as indexed by [3h]quinuclidinyl benzilate (qnb) binding and choline acetyltransferase (chat) levels in the hippocampus and frontal cortex of adult rats. |
1990-03-08 |
2023-08-11 |
rat |
| A Lehmann, M Sandber. In vivo substitution of choline for sodium evokes a selective osmoinsensitive increase of extracellular taurine in the rat hippocampus. Journal of neurochemistry. vol 54. issue 1. 1990-01-19. PMID:2293605. |
in vivo substitution of choline for sodium evokes a selective osmoinsensitive increase of extracellular taurine in the rat hippocampus. |
1990-01-19 |
2023-08-11 |
rat |
| K Kolasa, E Palazzi, P Salmoiraghi, G Guiso, S Caccia, S Garattini, S Consol. Mode of action of tiaspirone on the central cholinergic system. Naunyn-Schmiedeberg's archives of pharmacology. vol 340. issue 3. 1989-12-12. PMID:2572973. |
tiaspirone, however, was found to be a competitive, reversible inhibitor of the sodium-dependent high-affinity choline uptake (sdhacu) by crude hippocampal and striatal synaptosomal preparations, giving ic50 values of respectively 3.69 microm and 1.14 microm. |
1989-12-12 |
2023-08-11 |
rat |
| G S Zubenko, I Hani. Cholinergic and noradrenergic toxicity of intraventricular aluminum chloride in the rat hippocampus. Brain research. vol 498. issue 2. 1989-11-17. PMID:2790490. |
the effects of the intraventricular administration of aluminum chloride (alcl3) on high affinity choline transport (hacht) and norepinephrine concentration were examined in the hippocampus of the rat. |
1989-11-17 |
2023-08-11 |
rat |
| P J Coffey, J Feldon, S Mitchell, J Sinden, J A Gray, J N Rawlin. Ibotenate-induced total septal lesions reduce resistance to extinction but spare the partial reinforcement extinction effect in the rat. Experimental brain research. vol 77. issue 1. 1989-11-08. PMID:2792258. |
in experiment 3, neurochemical analysis of the hippocampus in rats with ibotenic acid-induced lesions demonstrated that choline acetyl-transferase levels were reduced to the same extent as in rats with comparable conventional lesions. |
1989-11-08 |
2023-08-11 |
rat |
| A Toumane, T Durkin, A Marighetto, R Jaffar. The durations of hippocampal and cortical cholinergic activation induced by spatial discrimination testing of mice in an eight-arm radial maze decrease as a function of acquisition. Behavioral and neural biology. vol 52. issue 2. 1989-11-01. PMID:2803178. |
sodium-dependent high-affinity choline uptake velocities in p2 fractions of the hippocampus and cortex of mice were analyzed at different times following both the first (day 1) and last (day 9) daily sessions of a spatial discrimination testing procedure in an eight-arm radial maze. |
1989-11-01 |
2023-08-11 |
mouse |