| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R L Buyukuysal, R J Wurtma. Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes. Brain research. vol 482. issue 2. 1989-06-01. PMID:2539887. |
we have compared the effects of tetrahydroaminoacridine (tha), 4-aminopyridine (4-ap) and tetraethylammonium (tea) on high affinity choline uptake and the release of newly synthesized acetylcholine (ach) from striatal and hippocampal synaptosomes, and on choline acetyltransferase (chat) activity in rat striatal synaptosomes. |
1989-06-01 |
2023-08-11 |
rat |
| R L Buyukuysal, R J Wurtma. Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes. Brain research. vol 482. issue 2. 1989-06-01. PMID:2539887. |
present data show that, in spite of these similarities, these compounds produce opposite effects on net choline uptake by striatal and hippocampal synaptosomes. |
1989-06-01 |
2023-08-11 |
rat |
| B Daschmann, C Allgaier, R Nakov, G Herttin. Staurosporine counteracts the phorbol ester-induced enhancement of neurotransmitter release in hippocampus. Archives internationales de pharmacodynamie et de therapie. vol 296. 1989-05-10. PMID:2907278. |
slices of rabbit hippocampus, prelabelled with either [3h]noradrenaline, [3h]5-hydroxytryptamine or [3h]choline were superfused with physiological medium. |
1989-05-10 |
2023-08-11 |
rabbit |
| D Galey, A Toumane, T Durkin, R Jaffar. In vivo modulation of septo-hippocampal cholinergic activity in mice: relationships with spatial reference and working memory performance. Behavioural brain research. vol 32. issue 2. 1989-05-04. PMID:2923659. |
combined neurochemical and behavioural analyses revealed significant correlations between hippocampal sodium-dependent high-affinity choline uptake activation induced by testing and performance measures. |
1989-05-04 |
2023-08-11 |
mouse |
| N A Muma, P P Rowel. Effects of chronic choline and lecithin on mouse hippocampal dendritic spine density. Experimental aging research. vol 14. issue 2-3. 1989-05-04. PMID:3234454. |
effects of chronic choline and lecithin on mouse hippocampal dendritic spine density. |
1989-05-04 |
2023-08-11 |
mouse |
| N A Muma, P P Rowel. Effects of chronic choline and lecithin on mouse hippocampal dendritic spine density. Experimental aging research. vol 14. issue 2-3. 1989-05-04. PMID:3234454. |
the results indicate that dietary supplementation may have different effects in different brain areas and that the relative increase in learning and memory function in aged animals given a choline or lecithin enriched diet is not due to an increase in hippocampal dendritic spine density. |
1989-05-04 |
2023-08-11 |
mouse |
| K F Funk, J Schmid. [Cholinergic effects of nootropics]. Biomedica biochimica acta. vol 47. issue 4-5. 1989-04-25. PMID:3149192. |
a single dose of pramiracetam enhances the choline uptake in cortex and hippocampus. |
1989-04-25 |
2023-08-11 |
Not clear |
| N A Muma, P P Rowell, G S Schult. Effects of long-term dietary choline and phosphatidylcholine administration on muscarinic receptors in aged mouse brain. Neurological research. vol 10. issue 3. 1989-02-28. PMID:2905774. |
choline levels were unaffected by the various diets, however phosphatidylcholine treatment resulted in an increase in phosphatidylcholine in the cortex and somewhat in the hippocampus. |
1989-02-28 |
2023-08-11 |
mouse |
| L Wecker, G Cawley, S Rotherme. Acute choline supplementation in vivo enhances acetylcholine synthesis in vitro when neurotransmitter release is increased by potassium. Journal of neurochemistry. vol 52. issue 2. 1989-02-23. PMID:2562990. |
for these experiments, hippocampal and striatal slices were prepared form rats that had received saline or an acute injection of choline. |
1989-02-23 |
2023-08-11 |
rat |
| L Wecker, G Cawley, S Rotherme. Acute choline supplementation in vivo enhances acetylcholine synthesis in vitro when neurotransmitter release is increased by potassium. Journal of neurochemistry. vol 52. issue 2. 1989-02-23. PMID:2562990. |
although the molar concentration of choline achieved in the incubation media at the end of the 10-min period did not differ between groups, the mobilization of free choline from bound stores was significantly greater in hippocampal slices from the choline-injected group than the controls. |
1989-02-23 |
2023-08-11 |
rat |
| A Horita, M A Carin. Intraseptal microinjection of adrenocorticotropic hormone1-24 antagonizes pentobarbital-induced narcosis and depression of hippocampal cholinergic activity. The Journal of pharmacology and experimental therapeutics. vol 247. issue 3. 1989-01-31. PMID:2905004. |
acth1-24 also increased hippocampal sodium-dependent high affinity choline uptake activity that had been depressed by the barbiturate. |
1989-01-31 |
2023-08-11 |
rat |
| H Lai, A Horita, A W Gu. Acute low-level microwave exposure and central cholinergic activity: studies on irradiation parameters. Bioelectromagnetics. vol 9. issue 4. 1988-12-16. PMID:3190763. |
sodium-dependent high-affinity choline uptake was measured in the striatum, frontal cortex, hippocampus, and hypothalamus of rats after acute exposure (45 min) to pulsed (2 microseconds, 500 pps) or continuous-wave 2,450-mhz microwaves in cylindrical waveguides (guy et al. |
1988-12-16 |
2023-08-11 |
rat |
| H Lai, A Horita, A W Gu. Acute low-level microwave exposure and central cholinergic activity: studies on irradiation parameters. Bioelectromagnetics. vol 9. issue 4. 1988-12-16. PMID:3190763. |
regardless of the exposure system used, hippocampal choline uptake was decreased after exposure to pulsed but not continuous-wave microwaves. |
1988-12-16 |
2023-08-11 |
rat |
| A Toumane, T Durkin, A Marighetto, D Galey, R Jaffar. Differential hippocampal and cortical cholinergic activation during the acquisition, retention, reversal and extinction of a spatial discrimination in an 8-arm radial maze by mice. Behavioural brain research. vol 30. issue 3. 1988-12-06. PMID:3178994. |
high-affinity choline uptake velocities in the hippocampus and cortex were analyzed, in parallel, at various periods during the acquisition, over 8 days, as were the subsequent retention, reversal and extinction of a spatial discrimination in an 8-arm radial maze. |
1988-12-06 |
2023-08-11 |
mouse |
| M Gallagher, M A Pelleymounte. An age-related spatial learning deficit: choline uptake distinguishes "impaired" and "unimpaired" rats. Neurobiology of aging. vol 9. issue 4. 1988-11-30. PMID:3185855. |
in this study, sodium-dependent high-affinity choline uptake (hacu) was used to monitor hippocampal function in response to training on a spatial task. |
1988-11-30 |
2023-08-11 |
human |
| G V Johnson, M Simonato, R S Jop. Dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: effects of nerve growth factor, GM1 ganglioside, and vitamin E. Neurochemical research. vol 13. issue 8. 1988-11-21. PMID:3173620. |
dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: effects of nerve growth factor, gm1 ganglioside, and vitamin e. ethylcholine mustard aziridinium ion (ecma) was infused intracerebroventricularly (icv) to rats followed by measurement of two markers of presynaptic cholinergic neurons, choline acetyltransferase (chat) activity and high affinity choline transport (hacht), in the hippocampus and cortex. |
1988-11-21 |
2023-08-11 |
rat |
| A Horita, M A Carino, C Chin. Codeine produces a cholinergically mediated analeptic effect in rats and rabbits. Pharmacology, biochemistry, and behavior. vol 30. issue 1. 1988-10-31. PMID:2902643. |
in rats the analeptic activity correlated with the reversal of the diazepam-induced fall in sodium dependent high affinity choline uptake in hippocampal and cortical synaptosomes. |
1988-10-31 |
2023-08-11 |
rat |
| V E Grimm, B Friede. Prenatal caffeine causes long lasting behavioral and neurochemical changes. The International journal of neuroscience. vol 41. issue 1-2. 1988-09-26. PMID:3410649. |
the neurochemical studies carried out at 2-3 months of age revealed an increase in choline uptake in hippocampus, mainly in the animals treated with the lower doses of caffeine and higher protein concentration (microgram/mg wet tissue) in the cortex or hippocampus of offspring exposed to the higher doses of caffeine. |
1988-09-26 |
2023-08-11 |
rat |
| P T Carroll, M T Iv. Effect of 2-(4-phenylpiperidino)cyclohexanol (AH 5183) on the veratridine-induced increase in acetylcholine synthesis by rat hippocampal tissue. Journal of neurochemistry. vol 51. issue 3. 1988-09-26. PMID:3411328. |
when minces of rat hippocampal tissue were loaded with [14c]choline and subsequently depolarized with veratridine, an increase in the synthesis of [14c]ach occurred that could be abolished by l-ah 5183 (75 nm). |
1988-09-26 |
2023-08-11 |
rat |
| L Wecke. Influence of dietary choline availability and neuronal demand on acetylcholine synthesis by rat brain. Journal of neurochemistry. vol 51. issue 2. 1988-08-24. PMID:3392542. |
in contrast, acetylcholine synthesis and release by striatal and hippocampal slices from choline-deficient rats, animals that had circulating choline levels that were 80% of control values, decreased significantly; the production of free choline by these tissues was also depressed. |
1988-08-24 |
2023-08-11 |
rat |