| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carrie L Heusner, Thomas S Hnasko, Mark S Szczypka, Yuhong Liu, Matthew J During, Richard D Palmite. Viral restoration of dopamine to the nucleus accumbens is sufficient to induce a locomotor response to amphetamine. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867267. |
dopamine deficient (dd) mice, in which tyrosine hydroxylase (th) has been specifically inactivated in dopaminergic neurons, have a blunted response to amphetamine, indicating that the hyperlocomotive response requires dopamine. |
2003-09-16 |
2023-08-12 |
mouse |
| Nestor G Davila, Laura J Blakemore, Paul Q Tromble. Dopamine modulates synaptic transmission between rat olfactory bulb neurons in culture. Journal of neurophysiology. vol 90. issue 1. 2003-09-12. PMID:12611989. |
immunocytochemical analysis confirmed the expression of tyrosine hydroxylase, the rate-limiting enzyme for dopamine synthesis, in a subpopulation of cultured neurons. |
2003-09-12 |
2023-08-12 |
rat |
| K Fuxe, K X Jacobsen, M Höistad, B Tinner, A Jansson, W A Staines, L F Agnat. The dopamine D1 receptor-rich main and paracapsular intercalated nerve cell groups of the rat amygdala: relationship to the dopamine innervation. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809694. |
the relationship of terminals positive for both tyrosine hydroxylase and dopamine beta-hydroxylase (noradrenaline and/or adrenaline) to terminals positive for tyrosine hydroxylase but negative for dopamine beta-hydroxylase (dopamine terminals) was studied in relation to the d1-receptor immunoreactivity in adjacent sections at various rostrocaudal levels. |
2003-09-12 |
2023-08-12 |
rat |
| Samuel Park, Timothy J Geddes, Jonathan A Javitch, Donald M Kuh. Dopamine prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide: is nitrotyrosine formation an early step in dopamine neuronal damage? The Journal of biological chemistry. vol 278. issue 31. 2003-09-10. PMID:12771134. |
dopamine prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide: is nitrotyrosine formation an early step in dopamine neuronal damage? |
2003-09-10 |
2023-08-12 |
human |
| Samuel Park, Timothy J Geddes, Jonathan A Javitch, Donald M Kuh. Dopamine prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide: is nitrotyrosine formation an early step in dopamine neuronal damage? The Journal of biological chemistry. vol 278. issue 31. 2003-09-10. PMID:12771134. |
peroxynitrite-induced nitration of tyrosine residues in tyrosine hydroxylase (th) may even be one of the earliest biochemical events associated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced damage to dopamine neurons. |
2003-09-10 |
2023-08-12 |
human |
| Yotam Sagi, Marta Weinstock, Moussa B H Youdi. Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor. Journal of neurochemistry. vol 86. issue 2. 2003-08-21. PMID:12871570. |
on chronic treatment in mice it attenuated striatal dopamine depletion induced by mptp and prevented the reduction in striatal tyrosine hydroxylase activity, like selective b and non-selective mao inhibitors. |
2003-08-21 |
2023-08-12 |
mouse |
| Giuseppe Battaglia, Francesco Fornai, Carla Letizia Busceti, Giuseppe Lembo, Ferdinando Nicoletti, Antonio De Blas. Alpha-1B adrenergic receptor knockout mice are protected against methamphetamine toxicity. Journal of neurochemistry. vol 86. issue 2. 2003-08-21. PMID:12871582. |
with 2 h of interval) induced a massive degeneration of the nigro-striatal pathway, as reflected by a 50% reduction in the striatal levels of dopamine (da) and 3,4-dihydroxyphenylacetic acid (dopac), by a substantial reduction in striatal tyrosine hydroxylase and high-affinity da transporter immunostaining, and by the development of reactive gliosis. |
2003-08-21 |
2023-08-12 |
mouse |
| Yasushi Kitaoka, Toshio Kumai, Kazuyuki Isenoumi, Yuka Kitaoka, Masamitsu Motoki, Shinichi Kobayashi, Satoki Uen. Neuroprotective effect of nitric oxide against NMDA-induced neurotoxicity in the rat retina is associated with tyrosine hydroxylase expression. Brain research. vol 977. issue 1. 2003-08-14. PMID:12788512. |
n-methyl-d-aspartate (nmda) may affect dopaminergic cells, which contain tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine synthesis. |
2003-08-14 |
2023-08-12 |
rat |
| Stefan R Pulver, Vatsala Thirumalai, Kathryn S Richards, Eve Marde. Dopamine and histamine in the developing stomatogastric system of the lobster Homarus americanus. The Journal of comparative neurology. vol 462. issue 4. 2003-08-08. PMID:12811809. |
we used antibodies against tyrosine hydroxylase (th) and histamine to map the distribution and developmental acquisition of the dopamine and histamine neurons in the stns of the lobster, homarus americanus. |
2003-08-08 |
2023-08-12 |
lobster |
| Seong Who Kim, Yeon Joo Jang, Jin Woo Chang, Onyou Hwan. Degeneration of the nigrostriatal pathway and induction of motor deficit by tetrahydrobiopterin: an in vivo model relevant to Parkinson's disease. Neurobiology of disease. vol 13. issue 2. 2003-08-08. PMID:12828940. |
intrastriatal bh4 injection caused a loss of tyrosine hydroxylase immunoreactivity and decreased dopamine content. |
2003-08-08 |
2023-08-12 |
Not clear |
| S Pompolo, A Pereira, T Kaneko, I J Clark. Seasonal changes in the inputs to gonadotropin-releasing hormone neurones in the ewe brain: an assessment by conventional fluorescence and confocal microscopy. Journal of neuroendocrinology. vol 15. issue 5. 2003-08-07. PMID:12694380. |
using double-labelling immunohistochemistry, we counted close appositions between gnrh cells and varicosities that were immunoreactive for either glutamic acid decarboxylase (gad; for gamma-amino butyric acid-gaba-neurones), dopamine beta hydroxylase (dbh; for noradrenergic neurones), vesicular glutamate transporter-1 (vglut-1, for glutamatergic neurones), neuropeptide y (npy) and tyrosine hydroxylase (th; for dopaminergic/noradrenergic neurones). |
2003-08-07 |
2023-08-12 |
Not clear |
| K Wasowic. Effect of total or partial uterus extirpation on uterus-projecting neurons in porcine inferior mesenteric ganglion. A. Changes in expression of transmitter-synthesizing enzymes--tyrosine hydroxylase, dopamine beta-hydroxylase and choline acetyltransferase. Polish journal of veterinary sciences. vol 6. issue 2. 2003-07-29. PMID:12817784. |
changes in expression of transmitter-synthesizing enzymes--tyrosine hydroxylase, dopamine beta-hydroxylase and choline acetyltransferase. |
2003-07-29 |
2023-08-12 |
Not clear |
| K Wasowic. Effect of total or partial uterus extirpation on uterus-projecting neurons in porcine inferior mesenteric ganglion. A. Changes in expression of transmitter-synthesizing enzymes--tyrosine hydroxylase, dopamine beta-hydroxylase and choline acetyltransferase. Polish journal of veterinary sciences. vol 6. issue 2. 2003-07-29. PMID:12817784. |
expression of tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh) and choline acetyltransferase (chat) was studied with immunohistochemistry, in situ hybridization, rt-pcr and immunoblotting in two populations of neurons of porcine inferior mesenteric ganglion (img) projecting to the uterine horn and uterine cervix after axotomy induced by partial or total uterus extirpation in sexually immature gilts. |
2003-07-29 |
2023-08-12 |
Not clear |
| R Kurosaki, Y Muramatsu, H Watanabe, M Michimata, M Matsubara, Y Imai, T Arak. Role of dopamine transporter against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice. Metabolic brain disease. vol 18. issue 2. 2003-07-24. PMID:12822832. |
we investigated the alterations of dopamine transporter (dat)-immunopositive cells against mptp neurotoxicity, in comparison with tyrosine hydroxylase (th)-immunopositive neurons and glial fibrillary acidic protein (gfap)-immunopositive cells. |
2003-07-24 |
2023-08-12 |
mouse |
| Graeme Eisenhofer, Hua Tian, Courtney Holmes, Jun Matsunaga, Suzanne Roffler-Tarlov, Vincent J Hearin. Tyrosinase: a developmentally specific major determinant of peripheral dopamine. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 10. 2003-07-17. PMID:12832289. |
l-3,4-dihydroxyphenylalanine, the immediate precursor of dopamine, can be formed by two enzymes: tyrosine hydroxylase (th) in catecholamine-producing neurons and chromaffin cells and tyrosinase in melanocytes. |
2003-07-17 |
2023-08-12 |
mouse |
| Rudolph Spangler, Noel L Goddard, Nicole M Avena, Bartley G Hoebel, Sarah F Leibowit. Elevated D3 dopamine receptor mRNA in dopaminergic and dopaminoceptive regions of the rat brain in response to morphine. Brain research. Molecular brain research. vol 111. issue 1-2. 2003-07-16. PMID:12654507. |
tissues were assayed for d1, d2 and d3 dopamine receptor mrnas (d1r, d2r and d3r), as well as for mrnas for tyrosine hydroxylase (th) and the dopamine transporter (dat). |
2003-07-16 |
2023-08-12 |
rat |
| Yi Ai, William Markesbery, Zhiming Zhang, Richard Grondin, Dennis Elseberry, Greg A Gerhardt, Don M Gas. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. The Journal of comparative neurology. vol 461. issue 2. 2003-07-16. PMID:12724841. |
gdnf was carried by retrograde transport to dopamine neurons in the ipsilateral substantia nigra, stimulating an 18% increase in the number of tyrosine hydroxylase (th)-positive dopamine neurons and a 28% increase in dopamine neuron perikaryal size. |
2003-07-16 |
2023-08-12 |
monkey |
| Brian Dean, Robyn Bradbury, David Leon Copolo. Cannabis-sensitive dopaminergic markers in postmortem central nervous system: changes in schizophrenia. Biological psychiatry. vol 53. issue 7. 2003-07-11. PMID:12679236. |
this study investigated if changes in pre-synaptic markers on dopaminergic neurons (dopamine transporter [dat], tyrosine hydroxylase [th]) were present in the caudate from subjects with schizophrenia who had delta(9)(-)tetrahydrocannabinol (thc) in their blood at autopsy. |
2003-07-11 |
2023-08-12 |
human |
| Bistra B Nankova, Jennifer Chua, Ravi Mishra, Catherine D Kobasiuk, Edmund F La Gamm. Nicotinic induction of preproenkephalin and tyrosine hydroxylase gene expression in butyrate-differentiated rat PC12 cells: a model for adaptation to gut-derived environmental signals. Pediatric research. vol 53. issue 1. 2003-07-08. PMID:12508089. |
in this report, we examined the interaction between butyrate differentiation of rat pheochromocytoma cells and cholinergic-nicotinic induction of the neuropeptide (enkephalin) and catecholamine-related biosynthetic enzymes (tyrosine hydroxylase, dopamine beta-hydroxylase, phenylethanolamine n-methyltransferase). |
2003-07-08 |
2023-08-12 |
human |
| Luciane V Sita, Carol F Elias, Jackson C Bittencour. Dopamine and melanin-concentrating hormone neurons are distinct populations in the rat rostromedial zona incerta. Brain research. vol 970. issue 1-2. 2003-07-08. PMID:12706266. |
medial zi synthesizes dopamine (a13 group) and tyrosine hydroxylase (th, a catecholamine synthesizing enzyme), which has been considered a neurochemical marker for this region. |
2003-07-08 |
2023-08-12 |
rat |