| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonas Lindblom, Andreas Johansson, Andreas Holmgren, Elisabeth Grandin, Carina Nedergård, Robert Fredriksson, Helgi B Schiöt. Increased mRNA levels of tyrosine hydroxylase and dopamine transporter in the VTA of male rats after chronic food restriction. The European journal of neuroscience. vol 23. issue 1. 2006-04-06. PMID:16420427. |
food restriction strongly increased mrna levels of tyrosine hydroxylase and the dopamine transporter in the ventral tegmental area. |
2006-04-06 |
2023-08-12 |
rat |
| Naira Pereyra-Muñoz, Concepción Rugerio-Vargas, Mariana Angoa-Pérez, Gabino Borgonio-Pérez, Selva Rivas-Arancibi. Oxidative damage in substantia nigra and striatum of rats chronically exposed to ozone. Journal of chemical neuroanatomy. vol 31. issue 2. 2006-04-04. PMID:16236481. |
each group was then tested for (1) motor activity, (2) quantification of lipid peroxidation levels, (3) klüver-barrera staining, and (4) immunohistochemistry for tyrosine hydroxylase (th), dopamine and adenosine 3',5'-monophosphate-regulated phosphoprotein of 32 kd (darpp-32), inducible nitric oxide synthase (inos), and superoxide dismutase (sod), to study neuronal alterations in striatum and substantia nigra. |
2006-04-04 |
2023-08-12 |
rat |
| J Vriend, Lisa Drege. Effects of haloperidol and melatonin on the in situ activity of nigrostriatal tyrosine hydroxylase in male Syrian hamsters. Life sciences. vol 78. issue 15. 2006-03-31. PMID:16263138. |
tissue content of dopamine and its metabolites, dopac and hva, was depressed in striatum of animals receiving haloperidol, and tyrosine hydroxylase (th) activity was significantly decreased 20-24 h after the last injection (from 1823 +/- 63 to 1139 +/- 85 pg l-dopa/mg tissue). |
2006-03-31 |
2023-08-12 |
Not clear |
| Marcin Bartłomiej Arciszewski, Krzysztof Wasowic. Neurochemical properties of the middle cervical ganglion in the sheep. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 188. issue 1. 2006-03-28. PMID:16447916. |
the neurochemical properties of the ovine middle cervical ganglion (mcg) were studied using antibodies raised against tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbetah), neuropeptide y (npy), substance p (sp), calcitonin gene-related peptide (cgrp), vasoactive intestinal polypeptide (vip) and galanin (gal). |
2006-03-28 |
2023-08-12 |
Not clear |
| B K Harvey, A Mark, J Chou, G J Chen, B J Hoffer, Y Wan. Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson's disease. Brain research. vol 1022. issue 1-2. 2006-03-23. PMID:15353217. |
moreover, exogenous application of bmp7 increases both the number of tyrosine hydroxylase (+) cells and dopamine (da) uptake in rat mesencephalic cell cultures. |
2006-03-23 |
2023-08-12 |
rat |
| F Bellivie. Schizophrenia, antipsychotics and diabetes: Genetic aspects. European psychiatry : the journal of the Association of European Psychiatrists. vol 20 Suppl 4. 2006-03-21. PMID:16459247. |
in addition, the dopamine d5 receptor on chromosome 5 and the tyrosine hydroxylase gene on chromosome 11 have both been suggested as candidate genes in schizophrenia and may also be implicated in susceptibility to poor glycaemic control. |
2006-03-21 |
2023-08-12 |
Not clear |
| Gong-Ping Liu, Nian Sh. The inhibitory effects of deltamethrin on dopamine biosynthesis in rat PC12 cells. Toxicology letters. vol 161. issue 3. 2006-03-16. PMID:16229977. |
flow cytometry (fcm) and rt-pcr technology were used to detect the levels of tyrosine hydroxylase (th) mrna and protein in pc12 cells treated with different doses of deltamethrin for 3 h or 12 h. deltamethrin decreased the levels of dopamine, th mrna and th protein in pc12 cells, and the increased dopamine levels induced by l-dopa at 20-50 microm were also decreased by deltamethrin for 3 h or 12 h. these results indicate that deltamethrin decreases dopamine content by the inhibition of th mrna and protein level in pc12 cells and maybe also have inhibitory effect on aromatic l-amino acid decarboxylase. |
2006-03-16 |
2023-08-12 |
rat |
| Wei Zhu, Kirk J Mantione, Lihua Shen, Patrick Cadet, Tobias Esch, Yannick Goumon, Enrica Bianchi, Dario Sonetti, George B Stefan. Tyrosine and tyramine increase endogenous ganglionic morphine and dopamine levels in vitro and in vivo: cyp2d6 and tyrosine hydroxylase modulation demonstrates a dopamine coupling. Medical science monitor : international medical journal of experimental and clinical research. vol 11. issue 11. 2006-03-02. PMID:16258388. |
tyrosine and tyramine increase endogenous ganglionic morphine and dopamine levels in vitro and in vivo: cyp2d6 and tyrosine hydroxylase modulation demonstrates a dopamine coupling. |
2006-03-02 |
2023-08-12 |
Not clear |
| Shu-Yuan Cheng, Dina Glazkova, Lidia Serova, Esther L Sabba. Effect of prolonged nicotine infusion on response of rat catecholamine biosynthetic enzymes to restraint and cold stress. Pharmacology, biochemistry, and behavior. vol 82. issue 3. 2006-03-02. PMID:16324736. |
in adrenal medulla (am), response of dopamine beta-hydroxylase (dbh), but not tyrosine hydroxylase (th) mrna, to both stressors was attenuated in nicotine-infused rats. |
2006-03-02 |
2023-08-12 |
rat |
| Yukari Takeuchi, Chie Hashizume, Esther Myung Ha Chon, Yukihide Momozawa, Koji Masuda, Takefumi Kikusui, Yuji Mor. Canine tyrosine hydroxylase (TH) gene and dopamine beta -hydroxylase (DBH) gene: their sequences, genetic polymorphisms, and diversities among five different dog breeds. The Journal of veterinary medical science. vol 67. issue 9. 2006-02-27. PMID:16210796. |
canine tyrosine hydroxylase (th) gene and dopamine beta -hydroxylase (dbh) gene: their sequences, genetic polymorphisms, and diversities among five different dog breeds. |
2006-02-27 |
2023-08-12 |
human |
| Yukari Takeuchi, Chie Hashizume, Esther Myung Ha Chon, Yukihide Momozawa, Koji Masuda, Takefumi Kikusui, Yuji Mor. Canine tyrosine hydroxylase (TH) gene and dopamine beta -hydroxylase (DBH) gene: their sequences, genetic polymorphisms, and diversities among five different dog breeds. The Journal of veterinary medical science. vol 67. issue 9. 2006-02-27. PMID:16210796. |
dopamine and noradrenaline are catecholamine neurotransmitters that are produced by biosynthetic enzymes such as tyrosine hydroxylase (th) and dopamine beta -hydroxylase (dbh). |
2006-02-27 |
2023-08-12 |
human |
| Manuel DeCastro, Bistra B Nankova, Parul Shah, Pranav Patel, Pradeep V Mally, Ravi Mishra, Edmund F La Gamm. Short chain fatty acids regulate tyrosine hydroxylase gene expression through a cAMP-dependent signaling pathway. Brain research. Molecular brain research. vol 142. issue 1. 2006-02-27. PMID:16219387. |
multiple intracellular and extracellular regulatory factors affect transcription of the tyrosine hydroxylase (th) gene encoding the rate-limiting enzyme in the biosynthesis of the neurotransmitters dopamine, norepinephrine and epinephrine. |
2006-02-27 |
2023-08-12 |
Not clear |
| David M Dietz, Jenica Tapocik, Meriem Gaval-Cruz, Mohamed Kabba. Dopamine transporter, but not tyrosine hydroxylase, may be implicated in determining individual differences in behavioral sensitization to amphetamine. Physiology & behavior. vol 86. issue 3. 2006-02-21. PMID:16126238. |
dopamine transporter, but not tyrosine hydroxylase, may be implicated in determining individual differences in behavioral sensitization to amphetamine. |
2006-02-21 |
2023-08-12 |
rat |
| David M Dietz, Jenica Tapocik, Meriem Gaval-Cruz, Mohamed Kabba. Dopamine transporter, but not tyrosine hydroxylase, may be implicated in determining individual differences in behavioral sensitization to amphetamine. Physiology & behavior. vol 86. issue 3. 2006-02-21. PMID:16126238. |
these results demonstrate the existence of individual differences in behavioral sensitization to amphetamine and suggest that dopamine transporter, but not tyrosine hydroxylase, may be a critical factor in the development and expression of behavioral sensitization to the locomotor activating effects of amphetamine. |
2006-02-21 |
2023-08-12 |
rat |
| Minoree Kohwi, Noriko Osumi, John L R Rubenstein, Arturo Alvarez-Buyll. Pax6 is required for making specific subpopulations of granule and periglomerular neurons in the olfactory bulb. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 30. 2006-02-15. PMID:16049175. |
interestingly, superficial granule neurons also express mrna for tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. |
2006-02-15 |
2023-08-12 |
mouse |
| Léder Leal Xavier, Giordano Gubert Viola, Anete Curte Ferraz, Claudio Da Cunha, Janyana Marcela Doro Deonizio, Carlos Alexandre Netto, Matilde Achava. A simple and fast densitometric method for the analysis of tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta and in the ventral tegmental area. Brain research. Brain research protocols. vol 16. issue 1-3. 2006-02-15. PMID:16310404. |
tyrosine hydroxylase (th) is a rate-limiting enzyme for dopamine synthesis, therefore immunohistochemistry for th can be used as an important marker of dopaminergic cell loss in these regions. |
2006-02-15 |
2023-08-12 |
Not clear |
| Yasutaka Hamasaka, Dick R Nässe. Mapping of serotonin, dopamine, and histamine in relation to different clock neurons in the brain of Drosophila. The Journal of comparative neurology. vol 494. issue 2. 2006-02-15. PMID:16320241. |
this was accomplished by employing clock neuron-specific gal4 lines driving green fluorescent protein (gfp) expression, combined with immunocytochemistry with antisera against serotonin, histamine, and tyrosine hydroxylase (for dopamine). |
2006-02-15 |
2023-08-12 |
drosophila_melanogaster |
| Miguel Angel Sánchez-González, Miguel Angel García-Cabezas, Beatriz Rico, Carmen Cavad. The primate thalamus is a key target for brain dopamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 26. 2006-02-14. PMID:15987937. |
we show that dopaminergic axons profusely target the human and macaque monkey thalamus using immunolabeling with three markers of the dopaminergic phenotype (tyrosine hydroxylase, dopamine, and the dopamine transporter). |
2006-02-14 |
2023-08-12 |
human |
| H K Holmer, M Keyghobadi, C Moore, C K Meshu. l-dopa-induced reversal in striatal glutamate following partial depletion of nigrostriatal dopamine with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience. vol 136. issue 1. 2006-02-14. PMID:16198485. |
there was a similar decrease in the relative density of tyrosine hydroxylase immunolabeling, a marker for dopamine terminals, within the dorsolateral striatum in both the acute and subchronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated groups that had been administered l-dopa. |
2006-02-14 |
2023-08-12 |
mouse |
| V I Mel'nikova, A V Lavrent'eva, V S Kudrin, K S Raevskii, M V Ugryumo. Dopamine synthesis by non-dopaminergic neurons in the arcuate nucleus of rat fetuses. Neuroscience and behavioral physiology. vol 35. issue 8. 2006-02-06. PMID:16132261. |
according to this hypothesis, neurons expressing tyrosine hydroxylase use l-tyrosine for the synthesis of l-dihydroxyphenylalanine (l-dopa), which then enters neurons expressing aromatic amino acid decarboxylase, which converts l-dopa to dopamine. |
2006-02-06 |
2023-08-12 |
rat |