| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martina Calamusa, Padmanabhan Paranji Pattabiraman, Nikita Pozdeyev, P Michael Iuvone, Alessandro Cellerino, Luciano Domenic. Specific alterations of tyrosine hydroxylase immunopositive cells in the retina of NT-4 knock out mice. Vision research. vol 47. issue 11. 2007-06-29. PMID:17350071. |
in particular, we studied neurons immunostained by an antibody recognizing tyrosine hydroxylase (th), the rate limiting enzyme for dopamine (da) synthesis. |
2007-06-29 |
2023-08-12 |
mouse |
| Scott Edwards, Danielle L Graham, Ryan K Bachtell, David W Sel. Region-specific tolerance to cocaine-regulated cAMP-dependent protein phosphorylation following chronic self-administration. The European journal of neuroscience. vol 25. issue 7. 2007-06-21. PMID:17439498. |
in contrast, sensitization to presynaptic regulation of synapsin(s9) phosphorylation developed in the hippocampal ca3 subregion while camp-dependent tyrosine hydroxylase(s40) phosphorylation decreased in striatal dopamine terminals. |
2007-06-21 |
2023-08-12 |
rat |
| Diane T Stephenson, Mary Abigail Childs, Qiu Li, Santos Carvajal-Gonzalez, Alan Opsahl, Mark Tengowski, Martin D Meglasson, Kalpana Merchant, Marina E Embor. Differential loss of presynaptic dopaminergic markers in Parkinsonian monkeys. Cell transplantation. vol 16. issue 3. 2007-06-21. PMID:17503735. |
tyrosine hydroxylase (th), dopamine transporter (dat), vesicular monoamine transporter 2 (vmat2), and amino acid decarboxylase (aadc) are widely used markers of dopaminergic neurons and terminals. |
2007-06-21 |
2023-08-12 |
monkey |
| Kazutaka Mogi, Katsuyasu Sakurai, Toru Ichimaru, Satoshi Ohkura, Yuji Mori, Hiroaki Okamur. Structure and chemical organization of the accessory olfactory bulb in the goat. Anatomical record (Hoboken, N.J. : 2007). vol 290. issue 3. 2007-06-20. PMID:17525945. |
sections were subjected to either nissl staining, klüver-barrera staining, lectin histochemistry, or immunohistochemistry for nitric oxide synthase (nos), neuropeptide y (npy), tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and glutamic acid decarboxylase (gad). |
2007-06-20 |
2023-08-12 |
Not clear |
| Valerie M Tatard, Gianluca D'Ippolito, Sylma Diabira, Alexander Valeyev, John Hackman, Micheline McCarthy, Thomas Bouckenooghe, Philippe Menei, Claudia N Montero-Menei, Paul C Schille. Neurotrophin-directed differentiation of human adult marrow stromal cells to dopaminergic-like neurons. Bone. vol 40. issue 2. 2007-06-04. PMID:17085092. |
supplementing the aforementioned multi-step process with sonic hedgehog, fibroblast growth factor 8, and retinoic acid increased the expression of molecules involved in dopaminergic differentiation and of tyrosine hydroxylase, the rate limiting enzyme of dopamine synthesis. |
2007-06-04 |
2023-08-12 |
human |
| Giselle M Petzinger, John P Walsh, Garnik Akopian, Elizabeth Hogg, Avery Abernathy, Pablo Arevalo, Patty Turnquist, Marta Vucković, Beth E Fisher, Daniel M Togasaki, Michael W Jakowe. Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 20. 2007-05-31. PMID:17507552. |
immunohistochemical staining analysis of striatal tyrosine hydroxylase and dopamine transporter proteins showed decreased expression in mptp plus exercise mice compared with mptp mice. |
2007-05-31 |
2023-08-12 |
mouse |
| Danhui Zhang, Arthi Kanthasamy, Yongjie Yang, Vellareddy Anantharam, Anumantha Kanthasam. Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 20. 2007-05-31. PMID:17507557. |
protein kinase c delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2a activity in dopaminergic neurons. |
2007-05-31 |
2023-08-12 |
mouse |
| Danhui Zhang, Arthi Kanthasamy, Yongjie Yang, Vellareddy Anantharam, Anumantha Kanthasam. Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 20. 2007-05-31. PMID:17507557. |
tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine synthesis, can be regulated by phosphorylation at multiple serine residues, including serine-40. |
2007-05-31 |
2023-08-12 |
mouse |
| Eva Hedlund, Jan Pruszak, Andrew Ferree, Angel Viñuela, Sunghoi Hong, Ole Isacson, Kwang-Soo Ki. Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations. Stem cells (Dayton, Ohio). vol 25. issue 5. 2007-05-16. PMID:17234989. |
selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations. |
2007-05-16 |
2023-08-12 |
mouse |
| Eva Hedlund, Jan Pruszak, Andrew Ferree, Angel Viñuela, Sunghoi Hong, Ole Isacson, Kwang-Soo Ki. Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations. Stem cells (Dayton, Ohio). vol 25. issue 5. 2007-05-16. PMID:17234989. |
these results illustrate the complexity of using genetic selection to purify mes cell-derived dopamine neurons and provide a comprehensive analysis of cell selection strategies based on tyrosine hydroxylase expression. |
2007-05-16 |
2023-08-12 |
mouse |
| Verona Villar-Cerviño, Xesús M Abalo, Begoña Villar-Cheda, Miguel Meléndez-Ferro, Emma Pérez-Costas, Gay R Holstein, Giorgio P Martinelli, María Celina Rodicio, Ramón Anadó. Presence of glutamate, glycine, and gamma-aminobutyric acid in the retina of the larval sea lamprey: comparative immunohistochemical study of classical neurotransmitters in larval and postmetamorphic retinas. The Journal of comparative neurology. vol 499. issue 5. 2007-05-08. PMID:17048230. |
the neurochemistry of the retina of the larval and postmetamorphic sea lamprey was studied via immunocytochemistry using antibodies directed against the major candidate neurotransmitters [glutamate, glycine, gamma-aminobutyric acid (gaba), aspartate, dopamine, serotonin] and the neurotransmitter-synthesizing enzyme tyrosine hydroxylase. |
2007-05-08 |
2023-08-12 |
Not clear |
| Timothy J Collier, Jack Lipton, Brian F Daley, Stephane Palfi, Yaping Chu, Caryl Sortwell, Roy A E Bakay, John R Sladek, Jeffrey H Kordowe. Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism. Neurobiology of disease. vol 26. issue 1. 2007-05-08. PMID:17254792. |
morphological and biochemical analyses of da-depleted and intact hemispheres revealed three primary findings: (1) the intact striatum exhibited age-related declines in dopamine (da) and homovanillic acid (hva) that were present by middle age; (2) in the mptp-treated striatum, the compensatory increase in da activity was absent in old monkeys; and (3) age-associated morphological changes included declines in the density of tyrosine hydroxylase (th) positive fibers in striatum, decreased nigral soma size, and optical density of th, but no significant loss of neurons. |
2007-05-08 |
2023-08-12 |
monkey |
| Jennifer E Tobin, Jing Cui, Jemma B Wilk, Jeanne C Latourelle, Jason M Laramie, Ann C McKee, Mark Guttman, Samer Karamohamed, Anita L DeStefano, Richard H Myer. Sepiapterin reductase expression is increased in Parkinson's disease brain tissue. Brain research. vol 1139. 2007-05-08. PMID:17270157. |
sepiapterin reductase catalyzes the final step in the biosynthetic pathway of tetrahydrobiopterin (bh(4)), an essential cofactor for aromatic amino acid hydrolases including tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. |
2007-05-08 |
2023-08-12 |
human |
| Loredana D'Este, Arianna Casini, Stefano Puglisi-Allegra, Simona Cabib, Tindaro G Rend. Comparative immunohistochemical study of the dopaminergic systems in two inbred mouse strains (C57BL/6J and DBA/2J). Journal of chemical neuroanatomy. vol 33. issue 2. 2007-05-08. PMID:17276033. |
the number of dopamine transporter (dat), vesicular monoamine transporter of type 2 (vmt) and tyrosine hydroxylase (th) immunoreactive cell bodies was significantly higher in the midbrain of dba mice than in c57 mice (on average +21.5%, p<0.001 in a10: +9.4% in a9, p<0.05: and +5.9% in a8, p<0.1). |
2007-05-08 |
2023-08-12 |
mouse |
| Carmen Piñuela, R Glenn Northcut. Immunohistochemical organization of the forebrain in the white sturgeon, Acipenser transmontanus. Brain, behavior and evolution. vol 69. issue 4. 2007-05-08. PMID:17299256. |
the distribution of substance p (sp), leucine-enkephalin (lenk), serotonin (5ht), dopamine (da), and tyrosine hydroxylase (th) was examined in the forebrain of the white sturgeon in order to evaluate several anatomical hypotheses based on cytoarchitectonics, and to gain a better understanding of the evolution of the forebrain in ray-finned fishes. |
2007-05-08 |
2023-08-12 |
Not clear |
| Fangwen Rao, Jennifer Wessel, Gen Wen, Lian Zhang, Brinda K Rana, Brian P Kennedy, Tiffany A Greenwood, Rany M Salem, Yuqing Chen, Srikrishna Khandrika, Bruce A Hamilton, Douglas W Smith, Niels-Henrik Holstein-Rathlou, Michael G Ziegler, Nicholas J Schork, Daniel T O'Conno. Renal albumin excretion: twin studies identify influences of heredity, environment, and adrenergic pathway polymorphism. Hypertension (Dallas, Tex. : 1979). vol 49. issue 5. 2007-05-07. PMID:17353515. |
albumin excretion associated with polymorphisms at multiple points in the adrenergic pathway: catecholamine biosynthesis (tyrosine hydroxylase), catabolism (monoamine oxidase a), storage/release (chromogranin a), receptor target (dopamine d1 receptor), and postreceptor signal transduction (sorting nexin 13 and rho kinase). |
2007-05-07 |
2023-08-12 |
Not clear |
| Yasuhiko Izumi, Hideyuki Sawada, Noriyuki Yamamoto, Toshiaki Kume, Hiroshi Katsuki, Shun Shimohama, Akinori Akaik. Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity. European journal of pharmacology. vol 557. issue 2-3. 2007-05-04. PMID:17161393. |
pramipexole reduced dopamine content but did not change the levels of total or phosphorylated tyrosine hydroxylase, a rate-limiting enzyme in dopamine synthesis. |
2007-05-04 |
2023-08-12 |
Not clear |
| Makoto Wada, Kenji Yoshimi, Noriyuki Higo, Yong-Ri Ren, Hideki Mochizuki, Yoshikuni Mizuno, Shigeru Kitazaw. Statistical parametric mapping of immunopositive cell density. Neuroscience research. vol 56. issue 1. 2007-04-27. PMID:16846658. |
we also applied the same analysis to tyrosine hydroxylase stained sections and detected significant decreases of dopamine neurons in the side of mpp+ injection. |
2007-04-27 |
2023-08-12 |
rat |
| Matthew P Mount, Arman Lira, David Grimes, Patrice D Smith, Sylvie Faucher, Ruth Slack, Hymie Anisman, Shawn Hayley, David S Par. Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 12. 2007-04-12. PMID:17376993. |
after this initial finding, we found that ifn-gamma-deficient mice displayed attenuated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced substantia nigra pars compacta dopaminergic cell loss along with reduced loss of striatal tyrosine hydroxylase and dopamine transporter fiber density. |
2007-04-12 |
2023-08-12 |
mouse |
| C S Weickert, M J Webster, P Gondipalli, D Rothmond, R J Fatula, M M Herman, J E Kleinman, M Aki. Postnatal alterations in dopaminergic markers in the human prefrontal cortex. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17123740. |
we measured the levels of tyrosine hydroxylase, the rate limiting enzyme in dopamine biosynthesis, using western immunoblotting. |
2007-04-11 |
2023-08-12 |
human |