| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
in vitro treatment of nicotine resulted in similar expressional changes of dopamine d(2) receptor and tyrosine hydroxylase at protein and mrna levels in dose- and time-dependent manner, whereas dopamine d(1) receptor did not reveal any positive output. |
2009-07-07 |
2023-08-12 |
rat |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
therefore, this study implied a new approach towards nicotine tolerance which is likely to be related to the modulation of dopamine d(2) receptor and tyrosine hydroxylase expressions by chronic and acute nicotine exposures in pc12 cell line. |
2009-07-07 |
2023-08-12 |
rat |
| Onarae V Rice, Alicia V Grande, Natasha Dehktyar, Magalie Bruneus, John K Robinson, Samuel J Gatle. Long-term effects of irradiation with iron-56 particles on the nigrostriatal dopamine system. Radiation and environmental biophysics. vol 48. issue 2. 2009-07-01. PMID:19259693. |
no effects were seen in brain sections stained for tyrosine hydroxylase, the classical marker for dopamine cells and nerve terminals. |
2009-07-01 |
2023-08-12 |
rat |
| Rosalinda C Roberts, Joy K Roche, Robert R Conley, Adrienne C Laht. Dopaminergic synapses in the caudate of subjects with schizophrenia: relationship to treatment response. Synapse (New York, N.Y.). vol 63. issue 6. 2009-06-30. PMID:19226604. |
the tissue was processed for the immunocytochemical localization of tyrosine hydroxylase (th), the synthesizing enzyme for dopamine, and prepared for electron microscopy. |
2009-06-30 |
2023-08-12 |
human |
| R Ammari, C Lopez, H Fiorentino, F Gonon, C Hammon. A mouse juvenile or adult slice with preserved functional nigro-striatal dopaminergic neurons. Neuroscience. vol 159. issue 1. 2009-06-25. PMID:19032976. |
this tilted parasagittal slice (380-400 microm) just medial to the subthalamic nucleus contains functional nigro-striatal neurons as assessed by morphological examination of tyrosine hydroxylase positive cell bodies and axons, combined with electrochemical assays of dopamine release in the striatum in response to stimulation of the substantia nigra pars compacta. |
2009-06-25 |
2023-08-12 |
mouse |
| A Bai, N Lu, Y Guo, J Chen, Z Li. Modulation of inflammatory response via alpha2-adrenoceptor blockade in acute murine colitis. Clinical and experimental immunology. vol 156. issue 2. 2009-06-24. PMID:19250273. |
the expression of tyrosine hydroxylase (th) and dopamine b-hydroxylase (dbh), two rate-limiting enzymes in catecholamine synthesis, was detected by immunohistochemistry in murine colitis. |
2009-06-24 |
2023-08-12 |
mouse |
| Yulin Li, Timothy South, Mei Han, Jiezhong Chen, Rui Wang, Xu-Feng Huan. High-fat diet decreases tyrosine hydroxylase mRNA expression irrespective of obesity susceptibility in mice. Brain research. vol 1268. 2009-06-24. PMID:19285041. |
tyrosine hydroxylase is the rate-limiting enzyme in the synthesis of dopamine, a key neurotransmitter in the regulation of food intake. |
2009-06-24 |
2023-08-12 |
mouse |
| Shun Wang, Xiu-jie Qi, Di Ha. [Effect of electroacupuncture scalp point-through-point therapy on the expression of tyrosine hydroxylase and dopamine transporter mRNAs in substantia nigra of Parkinson's disease model rats]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 29. issue 5. 2009-06-24. PMID:19489498. |
[effect of electroacupuncture scalp point-through-point therapy on the expression of tyrosine hydroxylase and dopamine transporter mrnas in substantia nigra of parkinson's disease model rats]. |
2009-06-24 |
2023-08-12 |
rat |
| Mara A Balda, Karen L Anderson, Yossef Itzha. The neuronal nitric oxide synthase (nNOS) gene contributes to the regulation of tyrosine hydroxylase (TH) by cocaine. Neuroscience letters. vol 457. issue 3. 2009-06-18. PMID:19429176. |
given the requirement of dopamine (da) transmission in cocaine-induced behavioral sensitization and the interactions between no and da systems, the present study investigated the role of the neuronal nitric oxide synthase (nnos) gene and the effect of cocaine on the expression of tyrosine hydroxylase (th)-immunoreactive (-ir) neurons. |
2009-06-18 |
2023-08-12 |
mouse |
| Qian Chen, Nan-Nan Huang, Jin-Tao Huang, Shen Chen, Jinjin Fan, Chaohong Li, Fu-Kang Xi. Sodium benzoate exposure downregulates the expression of tyrosine hydroxylase and dopamine transporter in dopaminergic neurons in developing zebrafish. Birth defects research. Part B, Developmental and reproductive toxicology. vol 86. issue 2. 2009-06-17. PMID:19294673. |
sodium benzoate exposure downregulates the expression of tyrosine hydroxylase and dopamine transporter in dopaminergic neurons in developing zebrafish. |
2009-06-17 |
2023-08-12 |
zebrafish |
| Kouichi C Nakamura, Fumino Fujiyama, Takahiro Furuta, Hiroyuki Hioki, Takeshi Kanek. Afferent islands are larger than mu-opioid receptor patch in striatum of rat pups. Neuroreport. vol 20. issue 6. 2009-06-16. PMID:19287319. |
we performed direct comparison between mor patches and dopamine islands in the caudate-putamen of rat pups, by double immunofluorescence labeling for mor and tyrosine hydroxylase. |
2009-06-16 |
2023-08-12 |
rat |
| Lichuan Yang, Noel Y Calingasan, Elizabeth J Wille, Kerry Cormier, Karen Smith, Robert J Ferrante, M Flint Bea. Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476553. |
the combination of the two agents produced additive neuroprotective effects against dopamine depletion in the striatum and loss of tyrosine hydroxylase neurons in the substantia nigra pars compacta (snpc) following chronic subcutaneous administration of mptp. |
2009-06-15 |
2023-08-12 |
mouse |
| Nicoletta Schintu, Lucia Frau, Marcello Ibba, Pierluigi Caboni, Arianna Garau, Ezio Carboni, Anna R Cart. PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease. The European journal of neuroscience. vol 29. issue 5. 2009-06-09. PMID:19245367. |
mice chronically treated with mptpp displayed typical features of pd, including impairment of motor and olfactory functions associated with partial loss of tyrosine hydroxylase (th)-positive neurons in the substantia nigra pars compacta (snc), decrease of dopamine (da) and 3,4-dihydroxyphenylacetic acid (dopac) content and dynorphin (dyn) mrna levels in the caudate-putamen (cpu), intense microglial and astroglial response in the snc and cpu. |
2009-06-09 |
2023-08-12 |
mouse |
| I E M de Jong, P J Steenbergen, E R de Kloe. Strain differences in the effects of adrenalectomy on the midbrain dopamine system: implication for behavioral sensitization to cocaine. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18420350. |
for that purpose, we have measured tyrosine hydroxylase (th) and dopamine transporter (dat) mrna and d1- and d2-like receptor binding in c57bl/6 and dba/2 mice that were i) unoperated, ii) adx or sham (sham) operated, or iii) adx or sham operated and subjected to a cocaine sensitization regimen (15.0 mg/kg cocaine on nine consecutive days, followed by a 7.5 mg/kg challenge after a 5-day withdrawal). |
2009-06-08 |
2023-08-12 |
mouse |
| Y-M Tian, X Chen, D-Z Luo, X-H Zhang, H Xue, L-F Zheng, N Yang, X-M Wang, J-X Zh. Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18420351. |
immunofluorescence, reverse transcription (rt)-real time polymerase chain reaction (pcr) and western blot were used to evaluate and compare the levels of mrna and protein expression of tyrosine hydroxylase (th) and dopamine transporter (dat) in the gi tract between normal and rodent pd models, as well as between 6-ohda-treated rats and mptp-treated mice. |
2009-06-08 |
2023-08-12 |
mouse |
| Sárka Lehtonen, Pekka T Männistö, Atso Raasmaj. Expression of tyrosine hydroxylase in the striatum of atipamezole-treated rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 36. issue 4-5. 2009-05-28. PMID:19159682. |
the effect of atipamezole, an alpha-2-adrenergic antagonist, was examined on the expression of tyrosine hydroxylase, the rate-limiting enzyme of synthesis of catecholamines such as dopamine, in the rat striatum. |
2009-05-28 |
2023-08-12 |
rat |
| Nikolai E Lazarov, Sebastian Reindl, Florian Fischer, Manfred Gratz. Histaminergic and dopaminergic traits in the human carotid body. Respiratory physiology & neurobiology. vol 165. issue 2-3. 2009-05-26. PMID:19022410. |
by contrast, catecholaminergic traits (tyrosine hydroxylase and vesicular monoamine transporter 1) were only detected in a subset of cb chemosensory cells at each age group while dopamine d2 receptors were expressed in the great majority of them. |
2009-05-26 |
2023-08-12 |
human |
| Junko Goto, Fumio Otsuka, Misuzu Yamashita, Jiro Suzuki, Hiroyuki Otani, Hiroko Takahashi, Tomoko Miyoshi, Yukari Mimura, Toshio Ogura, Hirofumi Makin. Enhancement of aldosterone-induced catecholamine production by bone morphogenetic protein-4 through activating Rho and SAPK/JNK pathway in adrenomedullar cells. American journal of physiology. Endocrinology and metabolism. vol 296. issue 4. 2009-05-21. PMID:19190257. |
aldosterone-induced dopamine accumulation was enhanced in accordance with the increase in the rate-limiting enzyme tyrosine hydroxylase (th). |
2009-05-21 |
2023-08-12 |
rat |
| Jun Wang, Hua-Min Xu, Hai-Dong Yang, Xi-Xun Du, Hong Jiang, Jun-Xia Xi. Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins. Neurochemistry international. vol 54. issue 1. 2009-04-24. PMID:19000728. |
the present studies showed that rg1 pre-treatment increased the dopamine and its metabolites contents in the striatum, as well as increased tyrosine hydroxylase expression in the sn. |
2009-04-24 |
2023-08-12 |
mouse |
| Alcmène Chalazonitis, Tuan D Pham, Zhishan Li, Daniel Roman, Udayan Guha, William Gomes, Lixin Kan, John A Kessler, Michael D Gersho. Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: relationship to timing of cell cycle exit. The Journal of comparative neurology. vol 509. issue 5. 2009-04-21. PMID:18537141. |
in contrast, noggin overexpression decreased numbers of neurons derived from precursors that exit the cell cycle late (gamma-aminobutyric acid, tyrosine hydroxylase [th], dopamine transporter, calcitonin gene-related peptide, trkc). |
2009-04-21 |
2023-08-12 |
mouse |