| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ljubica Gavrilovic, Natasa Spasojevic, Sladjana Dronja. Psychosocial stress-related changes in gene expression of norepinephrine biosynthetic enzymes in stellate ganglia of adult rats. Autonomic neuroscience : basic & clinical. vol 150. issue 1-2. 2009-11-16. PMID:19482560. |
in this study we investigated the changes in norepinephrine biosynthetic enzymes tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh) and phenylethanolamine n-methyltransferase (pnmt) gene expression in the stellate ganglia of naive controls and long-term socially isolated (12 weeks) adult rats and the response of these animals to additional immobilization stress. |
2009-11-16 |
2023-08-12 |
rat |
| Jason R Cannon, J Timothy Greenamyr. NeuN is not a reliable marker of dopamine neurons in rat substantia nigra. Neuroscience letters. vol 464. issue 1. 2009-11-03. PMID:19682546. |
in parkinson's disease models, neun has been widely used to determine if there is actual nigral dopamine neuron loss or simply loss of tyrosine hydroxylase expression, a prominent phenotypic marker. |
2009-11-03 |
2023-08-12 |
rat |
| Theodore A Slotkin, Frederic J Seidle. Benzo[a]pyrene impairs neurodifferentiation in PC12 cells. Brain research bulletin. vol 80. issue 1-2. 2009-11-02. PMID:19539729. |
we directly confirmed bap impairment of neurodifferentiation by measuring markers for the two neurotransmitter phenotypes expressed by pc12 cells: tyrosine hydroxylase (dopamine phenotype) and choline acetyltransferase (acetylcholine phenotype). |
2009-11-02 |
2023-08-12 |
Not clear |
| Rajesh S Yadav, Madhu Lata Sankhwar, Rajendra K Shukla, Ramesh Chandra, Aditya B Pant, Fakhrul Islam, Vinay K Khann. Attenuation of arsenic neurotoxicity by curcumin in rats. Toxicology and applied pharmacology. vol 240. issue 3. 2009-10-26. PMID:19631675. |
the arsenic treated rats also exhibited a decrease in the binding of striatal dopamine receptors (32%) and tyrosine hydroxylase (th) immunoreactivity (19%) in striatum. |
2009-10-26 |
2023-08-12 |
human |
| Seema Singh, Kavita Singh, Satya Prakash Gupta, Devendra Kumar Patel, Vinod Kumar Singh, Raj Kumar Singh, Mahendra Pratap Sing. Effect of caffeine on the expression of cytochrome P450 1A2, adenosine A2A receptor and dopamine transporter in control and 1-methyl 4-phenyl 1, 2, 3, 6-tetrahydropyridine treated mouse striatum. Brain research. vol 1283. 2009-10-23. PMID:19520064. |
tyrosine hydroxylase immunoreactivity, levels of dopamine and 1-methyl 4-phenylpyridinium ion (mpp(+)), expressions of cyp1a2, adenosine a(2a) receptor and dat and cyp1a2 catalytic activity were measured in control and treated mouse brain. |
2009-10-23 |
2023-08-12 |
mouse |
| G A Oganesyan, I V Romanova, E A Aristakesyan, V V Kuzik, D M Makina, I Yu Morina, A E Khramenkova, I V Artamokhina, V A Belov. The dopaminergic system of the telencephalo-diencephalic areas of the vertebrate brain in the organization of the sleep-waking cycle. Neuroscience and behavioral physiology. vol 39. issue 8. 2009-10-05. PMID:19779833. |
immunohistochemical studies of tyrosine hydroxylase content, this being the key enzyme in dopamine synthesis, in the striatum, supraoptic and arcuate nuclei, and zona incerta of the hypothalamus of sturgeon and mammals (rats) of three age groups (14 and 30 days and adults), in conditions of tactile and sleep-deprivation stressors. |
2009-10-05 |
2023-08-12 |
rat |
| Rui D S Prediger, Daniel Rial, Rodrigo Medeiros, Cláudia P Figueiredo, Richard L Doty, Reinaldo N Takahash. Risk is in the air: an intranasal MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) rat model of Parkinson's disease. Annals of the New York Academy of Sciences. vol 1170. 2009-09-25. PMID:19686204. |
such infusion decreased the expression of the enzyme tyrosine hydroxylase in the olfactory bulb and substantia nigra by means of apoptotic mechanisms, reducing dopamine levels in different brain structures, such as the olfactory bulb, striatum, and prefrontal cortex. |
2009-09-25 |
2023-08-12 |
rat |
| Seema Singh, Kavita Singh, Devendra Kumar Patel, Chetna Singh, Chandishwar Nath, Vinod Kumar Singh, Raj Kumar Singh, Mahendra Pratap Sing. The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection. Rejuvenation research. vol 12. issue 3. 2009-09-22. PMID:19594327. |
tyrosine hydroxylase (th)-immunoreactivity in the substantia nigra, the expression of nicotinic acetylcholine receptors (nachrs) alpha6 and alpha4, dopamine content, and 1-methyl-4-phenylpyridinium ion (mpp(+)) level in the striatum were measured to confirm the mptp-induced pd phenotype and nicotine-mediated neuroprotection. |
2009-09-22 |
2023-08-12 |
mouse |
| Miriam Schiff, Birgit Weinhold, Claudia Grothe, Herbert Hildebrand. NCAM and polysialyltransferase profiles match dopaminergic marker gene expression but polysialic acid is dispensable for development of the midbrain dopamine system. Journal of neurochemistry. vol 110. issue 5. 2009-09-21. PMID:19619134. |
as studied by quantitative real-time rt-pcr, mrna profiles of ncam and the polysialyltransferases, st8siaii and st8siaiv, matched the course of tyrosine hydroxylase, dopamine transporter, nur-related factor 1, and paired-like homeodomain transcription factor 3 expression, which were used as marker genes of dopaminergic development. |
2009-09-21 |
2023-08-12 |
mouse |
| Karley Y Little, Eric Ramssen, Ryan Welchko, Vitaly Volberg, Courtney J Roland, Bader Cassi. Decreased brain dopamine cell numbers in human cocaine users. Psychiatry research. vol 168. issue 3. 2009-09-17. PMID:19233481. |
the present experiment involved counting midbrain dopamine neurons utilizing both melanin and tyrosine hydroxylase immunoreactivity. |
2009-09-17 |
2023-08-12 |
human |
| Kentaro Nagane, Masaaki Kitada, Shohei Wakao, Mari Dezawa, Yasuhiko Tabat. Practical induction system for dopamine-producing cells from bone marrow stromal cells using spermine-pullulan-mediated reverse transfection method. Tissue engineering. Part A. vol 15. issue 7. 2009-09-16. PMID:19196136. |
microtubule-associated protein 2 and anti-beta-tubulin class iii+ neurons were successfully delivered from human, monkey, and mouse bmscs, and further treatment with trophic factors promoted differentiation of induced neuronal cells into dopamine-producing cells that were positive for tyrosine hydroxylase and secreted dopamine after high k+ stimulation in high-performance liquid chromatography analysis. |
2009-09-16 |
2023-08-12 |
mouse |
| Yunlan Du, Dehua Yang, Liang Li, Guangrui Luo, Ting Li, Xiaolan Fan, Qian Wang, Xin Zhang, Yi Wang, Weidong L. An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity. Autophagy. vol 5. issue 5. 2009-09-16. PMID:19337030. |
moreover, we demonstrated that rapamycin pretreatment increased tyrosine hydroxylase (th) protein level in dopamine (da) neurons, which was associated with its induction of autophagy to degrade aggregated proteins. |
2009-09-16 |
2023-08-12 |
Not clear |
| Jens Mittag, Sönke Friedrichsen, Anne Strube, Heike Heuer, Karl Baue. Analysis of hypertrophic thyrotrophs in pituitaries of athyroid Pax8-/- mice. Endocrinology. vol 150. issue 9. 2009-09-16. PMID:19477936. |
accordingly, tyrosine hydroxylase protein levels, enzyme activities, and ultimately dopamine concentrations were found to be strongly increased in the pituitaries of pax8(-/-) mice compared with wild-type animals. |
2009-09-16 |
2023-08-12 |
mouse |
| E Lagrue, B Abert, L Nadal, L Tabone, S Bodard, F Medja, A Lombes, S Chalon, P Castelna. MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood. Metabolic brain disease. vol 24. issue 2. 2009-09-14. PMID:19319673. |
this model also reproduced the biochemical and pathological features of ls: mptp increased plasmatic lactate levels (p = 0.023) and triggered basal ganglia degeneration, as evaluated through dopamine transporter (dat) autoradiography, tyrosine hydroxylase (th) immunohistochemistry, and dopamine dosage. |
2009-09-14 |
2023-08-12 |
mouse |
| Tri Wahyu Pangestiningsih, Anita Hendrickson, Koeswinarning Sigit, Dondin Sajuthi, Nurhidayat, Douglas M Bowde. Development of the area postrema: an immunohistochemical study in the macaque. Brain research. vol 1280. 2009-09-14. PMID:19460361. |
it was later invaded by tyrosine hydroxylase immunoreactive (th+) and dopamine beta-hydroxylase immunoreactive (dbh+) cells and fibers, suggesting a possible route for release of neurotransmitter directly into ventricular cerebrospinal fluid. |
2009-09-14 |
2023-08-12 |
monkey |
| Yi Sui, Davor Stanić, Doris Tomas, Bevyn Jarrott, Malcolm K Horn. Meloxicam reduces lipopolysaccharide-induced degeneration of dopaminergic neurons in the rat substantia nigra pars compacta. Neuroscience letters. vol 460. issue 2. 2009-09-02. PMID:19450656. |
using the intranigral lipopolysaccharide (lps) rat model, we show that meloxicam, a preferential cox-2 inhibitor, diminishes the activation of ox-42-immunoreactive (ir) microglia and reduces the loss of tyrosine hydroxylase (th)-ir dopamine (da) neurons in the substantia nigra pars compacta (snpc) that is normally induced by exposure to lps. |
2009-09-02 |
2023-08-12 |
rat |
| D Russo, C Mongardi Fantaguzzi, G Di Guardo, P Clavenzani, G Lalatta Costerbosa, C Ligios, R Chiocchett. Characterization of sheep (Ovis aries) palatine tonsil innervation. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19364524. |
immunoreactivity (ir) for tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuronal nitric oxide synthase (nnos), calcitonin gene-related peptide (cgrp), substance p (sp), and calcium-binding protein s100 (s100), was observed in the fibers around and within pt lymphoid nodules. |
2009-08-24 |
2023-08-12 |
Not clear |
| Jean-Pierre Louboutin, Lokesh Agrawal, Beverly A S Reyes, Elisabeth J Van Bockstaele, David S Straye. HIV-1 gp120 neurotoxicity proximally and at a distance from the point of exposure: protection by rSV40 delivery of antioxidant enzymes. Neurobiology of disease. vol 34. issue 3. 2009-08-17. PMID:19327399. |
dopaminergic sn neurons (expressing tyrosine hydroxylase, th, in the sn and dopamine transporter, dat, in the cp) were mostly affected: intra-cp gp120 caused approximately 50% dat+ sn neuron loss. |
2009-08-17 |
2023-08-12 |
rat |
| Laura E Bianco, Erica L Unger, Christopher J Earley, John L Bear. Iron deficiency alters the day-night variation in monoamine levels in mice. Chronobiology international. vol 26. issue 3. 2009-08-13. PMID:19360489. |
extracellular striatal da levels were 15-20% higher in all groups during the active dark phase compared to the inactive light phase, with correspondingly lower dopamine transporter (dat) and higher tyrosine hydroxylase levels. |
2009-08-13 |
2023-08-12 |
mouse |
| Jeannine Ma, Victoria E Shaw, John Mitrofani. Does melatonin help save dopaminergic cells in MPTP-treated mice? Parkinsonism & related disorders. vol 15. issue 4. 2009-08-10. PMID:18793863. |
brains were processed for routine tyrosine hydroxylase (th; rate limiting enzyme for dopamine production) immunochemistry and nissl staining. |
2009-08-10 |
2023-08-12 |
mouse |