| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J NouriNezhad, K Wasowicz, R Bukowski, C Skobowia. Analysis of the chemical coding of neurons in the intermediate thoracic ganglion of the pig. Polish journal of veterinary sciences. vol 13. issue 3. 2010-12-07. PMID:21033570. |
the localization and pattern of distribution of nerve cell bodies and fibers containing tyrosine hydroxylase (th), dopamine b-hydroxylase (dbh), neuropeptide y (npy), vasoactive intestinal polypeptide (vip), somatostatin (som), galanin (gal), methionine-enkephalin (met) as well as calcitonin gene-related peptide (cgrp), substance p (sp) and pituitary adenylate cyclase-activating peptide (pacap) was studied with immunohistochemistry. |
2010-12-07 |
2023-08-12 |
Not clear |
| Atsushi Sato, Osamu Nakagawasai, Koichi Tan-No, Hiroshi Onogi, Fukie Niijima, Takeshi Tadan. Influence of olfactory bulbectomy on maternal behavior and dopaminergic function in nucleus accumbens in mice. Behavioural brain research. vol 215. issue 1. 2010-12-06. PMID:20638419. |
furthermore, we measured tyrosine hydroxylase (th) levels using microphotometry and quantified dopamine d1- and d2-like receptors using autoradiography in the nucleus accumbens (nac). |
2010-12-06 |
2023-08-12 |
mouse |
| D Russo, C Bombardi, A Grandis, J B Furness, A Spadari, C Bernardini, R Chiocchett. Sympathetic innervation of the ileocecal junction in horses. The Journal of comparative neurology. vol 518. issue 19. 2010-12-06. PMID:20737599. |
immunoreactivity (ir) for tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuronal nitric oxide synthase (nnos), calcitonin gene-related peptide (cgrp), substance p (sp), and neuropeptide y (npy) was investigated. |
2010-12-06 |
2023-08-12 |
Not clear |
| A K M H Kober, M Aoyama, S Sugit. Immunohistochemical localization of catecholamine biosynthetic enzymes in the adrenal gland of the domestic fowl (Gallus domesticus). Poultry science. vol 89. issue 8. 2010-12-03. PMID:20634527. |
the present study investigated the cellular localization of 3 catecholamine biosynthetic enzymes, tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt) to identify and analyze the localization of norepinephrine (ne) and epinephrine (e) cells in the adrenal gland in the chicken using peroxidase-antiperoxidase immunohistochemical techniques. |
2010-12-03 |
2023-08-12 |
chicken |
| Katy M Webb, Michael Y Aksenov, Charles F Mactutus, Rosemarie M Booz. Evidence for developmental dopaminergic alterations in the human immunodeficiency virus-1 transgenic rat. Journal of neurovirology. vol 16. issue 2. 2010-12-02. PMID:20337512. |
findings from our model of choice, the hiv-1 transgenic rat, reveal a significant increase in phosphorylated tyrosine hydroxylase protein expression and a decrease in dopamine transporter mrna, without changes in tyrosine hydroxylase (th) or dopamine transporter (dat) protein or in more general markers of protein and gene expression levels in the hiv-1 transgenic rat midbrain. |
2010-12-02 |
2023-08-12 |
human |
| David M Thomas, Mariana Angoa Pérez, Dina M Francescutti-Verbeem, Mrudang M Shah, Donald M Kuh. The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum. Journal of neurochemistry. vol 115. issue 3. 2010-12-02. PMID:20722968. |
increases in 5ht levels with 5-hydroxytryptophan do not change meth-induced neurotoxicity to the da nerve endings as revealed by reductions in da, tyrosine hydroxylase and dopamine transporter levels. |
2010-12-02 |
2023-08-12 |
mouse |
| Brandon S Pruett, Michael F Salvator. GFR α-1 receptor expression in the aging nigrostriatal and mesoaccumbens pathways. Journal of neurochemistry. vol 115. issue 3. 2010-12-02. PMID:20731758. |
we recently reported that age-related bradykinesia was associated with reduced dopamine (da) tissue content, ser31 tyrosine hydroxylase (th) phosphorylation, and total th levels in substantia nigra (sn) only. |
2010-12-02 |
2023-08-12 |
rat |
| Oleg S Gorbatyuk, Shoudong Li, Kevin Nash, Marina Gorbatyuk, Alfred S Lewin, Layla F Sullivan, Ronald J Mandel, Weijun Chen, Craig Meyers, Fredric P Manfredsson, Nicholas Muzyczk. In vivo RNAi-mediated alpha-synuclein silencing induces nigrostriatal degeneration. Molecular therapy : the journal of the American Society of Gene Therapy. vol 18. issue 8. 2010-11-23. PMID:20551914. |
reduction of alpha-syn resulted in a rapid (4 week) reduction in the number of tyrosine hydroxylase (th) positive cells and striatal dopamine (da) on the injected side. |
2010-11-23 |
2023-08-12 |
rat |
| D A Lane, A Jaferi, M J Kreek, V M Picke. Acute and chronic cocaine differentially alter the subcellular distribution of AMPA GluR1 subunits in region-specific neurons within the mouse ventral tegmental area. Neuroscience. vol 169. issue 2. 2010-11-23. PMID:20553819. |
to test this hypothesis, we used electron microscopic immunolabeling of ampa glur1 subunits and tyrosine hydroxylase (th), the enzyme needed for dopamine synthesis, in the cortical-associated parabrachial (pb) and in the limbic-associated paranigral (pn) vta of adult male c57bl/6 mice receiving either a single injection (acute) or repeated escalating-doses for 14 days (chronic) of cocaine. |
2010-11-23 |
2023-08-12 |
mouse |
| Joanne Clark, Elizabeth L Clore, Kangni Zheng, Anthony Adame, Eliezer Masliah, David K Simo. Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice. PloS one. vol 5. issue 8. 2010-11-04. PMID:20808797. |
despite the transient nature of the impact of nac on brain glutathione, the loss of dopaminergic terminals at 1 year associated with snca overexpression was significantly attenuated by nac supplementation, as measured by immunoreactivity for tyrosine hydroxylase in the striatum (p = 0.007; unpaired, two-tailed t-test), with a similar but nonsignificant trend for dopamine transporter (dat) immunoreactivity. |
2010-11-04 |
2023-08-12 |
mouse |
| Cristiano R Jesse, Ethel A Wilhelm, Cristiani F Bortolatto, Cristina W Nogueir. Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice. Pharmacology, biochemistry, and behavior. vol 95. issue 3. 2010-11-01. PMID:20184917. |
in the fst was blocked with yohimbine (1mg/kg, i.p., an alpha(2)-adrenoceptor antagonist), alpha-methyl-para-tyrosine methyl ester (ampt, 100mg/kg, i.p., an inhibitor of tyrosine hydroxylase), efaroxan (1mg/kg, i.p., an imidazoline i(1)/alpha(2)-adrenoceptor antagonist), idazoxan (0.06mg/kg, i.p., an imidazoline i(2)/alpha(2)-adrenoceptor antagonist), antazoline (5mg/kg, i.p., a ligand with high affinity for the i(2) receptor), haloperidol (0.2mg/kg, i.p., a non selective dopamine receptor antagonist), sch23390 (0.05mg/kg, subcutaneously, s.c., a dopamine d(1) receptor antagonist), sulpiride (50mg/kg, i.p., a dopamine d(2) and d(3) receptor antagonist) but was not reversed by prazosin (1mg/kg, intraperitoneally, i.p., an alpha(1)-adrenoceptor antagonist) and caffeine (3mg/kg, i.p., a nonselective adenosine receptor antagonist). |
2010-11-01 |
2023-08-12 |
mouse |
| Lina Yao, Peidong Fan, Maria Arolfo, Zhan Jiang, M Foster Olive, Jeff Zablocki, Hai-Ling Sun, Nancy Chu, Jeongrim Lee, Hee-Yong Kim, Kwan Leung, John Shryock, Brent Blackburn, Ivan Diamon. Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis. Nature medicine. vol 16. issue 9. 2010-10-27. PMID:20729865. |
pka and pkc phosphorylate and activate tyrosine hydroxylase, further increasing dopamine synthesis in a positive-feedback loop. |
2010-10-27 |
2023-08-12 |
human |
| Lina Yao, Peidong Fan, Maria Arolfo, Zhan Jiang, M Foster Olive, Jeff Zablocki, Hai-Ling Sun, Nancy Chu, Jeongrim Lee, Hee-Yong Kim, Kwan Leung, John Shryock, Brent Blackburn, Ivan Diamon. Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis. Nature medicine. vol 16. issue 9. 2010-10-27. PMID:20729865. |
thp selectively inhibits phosphorylated (activated) tyrosine hydroxylase to reduce dopamine production via negative-feedback signaling. |
2010-10-27 |
2023-08-12 |
human |
| Jens Leander Johansen, Thomas Nikolaj Sager, Julie Lotharius, Louise Witten, Arne Mørk, Jan Egebjerg, Kenneth Thirstru. HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells. Journal of neurochemistry. vol 115. issue 1. 2010-10-13. PMID:20649842. |
in addition, hph inhibition elevates tyrosine hydroxylase expression and activity, which causes increased dopamine synthesis and release in both pc12 cells and a primary rat ventral mesencephalic cell culture. |
2010-10-13 |
2023-08-12 |
rat |
| Sarika Singh, Sachin Kumar, Madhu Dikshi. Involvement of the mitochondrial apoptotic pathway and nitric oxide synthase in dopaminergic neuronal death induced by 6-hydroxydopamine and lipopolysaccharide. Redox report : communications in free radical research. vol 15. issue 3. 2010-10-08. PMID:20594414. |
significant decreases in dopamine, 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), tyrosine hydroxylase (th) immunolabeling and mitochondrial complex-i activity were observed, with increase in cytochrome-c release and caspase-3 activation. |
2010-10-08 |
2023-08-12 |
rat |
| Maura L Perry, Gina M Leinninger, Rong Chen, Kathryn D Luderman, Hongyan Yang, Margaret E Gnegy, Martin G Myers, Robert T Kenned. Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. Journal of neurochemistry. vol 114. issue 3. 2010-10-06. PMID:20412389. |
leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of sprague-dawley rats. |
2010-10-06 |
2023-08-12 |
rat |
| Banthit Chetsawang, Jirapa Chetsawang, Piyarat Govitrapon. Protection against cell death and sustained tyrosine hydroxylase phosphorylation in hydrogen peroxide- and MPP-treated human neuroblastoma cells with melatonin. Journal of pineal research. vol 46. issue 1. 2010-09-21. PMID:18507712. |
in addition, the reduction of phosphorylation of tyrosine hydroxylase, the rate limiting enzyme in dopamine synthesis, and phosphorylation of cyclic amp responsive element-binding protein by h(2)o(2) and mpp(+) was also diminished by melatonin. |
2010-09-21 |
2023-08-12 |
human |
| Kumi O Kuroda, Veravej G Ornthanalai, Tadafumi Kato, Niall P Murph. FosB null mutant mice show enhanced methamphetamine neurotoxicity: potential involvement of FosB in intracellular feedback signaling and astroglial function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 3. 2010-09-07. PMID:19890265. |
methamphetamine-induced hyperthermia, brain dopamine content, and loss of tyrosine hydroxylase immunoreactivity in the striatum, however, were not different between genotypes. |
2010-09-07 |
2023-08-12 |
mouse |
| Hsiang-Shu Yin, Kevin Chen, Jean C Shih, Tai-Wei Tie. Down-regulated GABAergic expression in the olfactory bulb layers of the mouse deficient in monoamine oxidase B and administered with amphetamine. Cellular and molecular neurobiology. vol 30. issue 4. 2010-09-07. PMID:19902350. |
in the glol, the level of tyrosine hydroxylase was 39% lower in the ko mice than wt, implicating different dopamine content in the ko from wt. |
2010-09-07 |
2023-08-12 |
mouse |
| Richard W Morris, Samantha J Fung, Debora A Rothmond, Brent Richards, Sarah Ward, Pamela L Noble, Ruth A Woodward, Cynthia Shannon Weickert, James T Winslo. The effect of gonadectomy on prepulse inhibition and fear-potentiated startle in adolescent rhesus macaques. Psychoneuroendocrinology. vol 35. issue 6. 2010-09-07. PMID:20042297. |
at the end of the study, testosterone among the intact monkeys was also correlated with tyrosine hydroxylase levels in the putamen, suggesting the attenuation of ppi by gonadal sex hormones may be influenced by subcortical dopamine. |
2010-09-07 |
2023-08-12 |
monkey |