| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michal Zaleck. Localization and neurochemical characteristics of the extrinsic sympathetic neurons projecting to the pylorus in the domestic pig. Journal of chemical neuroanatomy. vol 43. issue 1. 2012-07-19. PMID:21903161. |
approximately 77% of the fb-positive cell bodies contained tyrosine hydroxylase (th), 87% dopamine β-hydroxylase (dβh), 40% neuropeptide y (npy), 12% somatostatin (som) and 7% galanin (gal). |
2012-07-19 |
2023-08-12 |
Not clear |
| K Misono, A Lessar. Apomorphine-evoked redistribution of neurokinin-3 receptors in dopaminergic dendrites and neuronal nuclei of the rat ventral tegmental area. Neuroscience. vol 203. 2012-07-19. PMID:22200547. |
vta sections were dual immunolabeled for the nk(3) receptor (immunogold) and the dopamine synthesizing enzyme tyrosine hydroxylase (th, immunoperoxidase). |
2012-07-19 |
2023-08-12 |
rat |
| Saif Ahmad, M Badruzzaman Khan, M Nasrul Hoda, Kanchan Bhatia, Rizwanul Haque, Inayat Saleem Fazili, Arshad Jamal, Jafar Salamt Khan, Deepshikha Pande Katar. Neuroprotective effect of sesame seed oil in 6-hydroxydopamine induced neurotoxicity in mice model: cellular, biochemical and neurochemical evidence. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22089932. |
increased tyrosine hydroxylase (th) expression in substantia nigra as well as dopamine and its metabolite dopac level in l+so group also support our findings that so may inhibit activation of nadph oxidase dependent inflammatory mechanism due to 6-ohda induced neurotoxicity in mice. |
2012-06-29 |
2023-08-12 |
mouse |
| Floriana Volpicelli, Roberto De Gregorio, Salvatore Pulcrano, Carla Perrone-Capano, Umberto di Porzio, Gian Carlo Bellench. Direct regulation of Pitx3 expression by Nurr1 in culture and in developing mouse midbrain. PloS one. vol 7. issue 2. 2012-06-29. PMID:22363463. |
during development the expression of nurr1 precedes that of pitx3 and those of typical dopaminergic markers such as tyrosine hydroxylase (th) and dopamine transporter (dat) that are directly regulated by nurr1. |
2012-06-29 |
2023-08-12 |
mouse |
| B A Morrow, R H Roth, D E Redmond, S Diano, J D Elswort. Susceptibility to a parkinsonian toxin varies during primate development. Experimental neurology. vol 235. issue 1. 2012-06-29. PMID:22366325. |
measures of dopamine, homovanillic acid, 1-methyl-pyridinium concentrations and tyrosine hydroxylase immunoreactive neurons indicated that at mid-gestation dopamine neurons are relatively vulnerable to mptp, whereas later in development or in the young primate these neurons are resistant to the neurotoxin. |
2012-06-29 |
2023-08-12 |
Not clear |
| Debora A Rothmond, Cynthia S Weickert, Maree J Webste. Developmental changes in human dopamine neurotransmission: cortical receptors and terminators. BMC neuroscience. vol 13. 2012-06-08. PMID:22336227. |
we assessed pre- and postsynaptic components of the dopamine system including tyrosine hydroxylase, the dopamine receptors (d1, d2 short and d2 long isoforms, d4, d5), catechol-o-methyltransferase, and monoamine oxidase (a and b) in the developing human dlpfc (6 weeks -50 years). |
2012-06-08 |
2023-08-12 |
human |
| Mariana Angoa-Pérez, Michael J Kane, Dina M Francescutti, Katherine E Sykes, Mrudang M Shah, Abiy M Mohammed, David M Thomas, Donald M Kuh. Mephedrone, an abused psychoactive component of 'bath salts' and methamphetamine congener, does not cause neurotoxicity to dopamine nerve endings of the striatum. Journal of neurochemistry. vol 120. issue 6. 2012-06-01. PMID:22191803. |
while mephedrone caused hyperthermia and locomotor stimulation, it did not lower striatal levels of dopamine, tyrosine hydroxylase or the dopamine transporter under any of the treatment conditions used presently. |
2012-06-01 |
2023-08-12 |
mouse |
| Zivjena Vucetic, Jesse Lea Carlin, Kathy Totoki, Teresa M Reye. Epigenetic dysregulation of the dopamine system in diet-induced obesity. Journal of neurochemistry. vol 120. issue 6. 2012-06-01. PMID:22220805. |
differential dna methylation was identified within the promoter regions of tyrosine hydroxylase (th) and dopamine transporter (dat), and the pattern of this response was consistent with the pattern of gene expression. |
2012-06-01 |
2023-08-12 |
mouse |
| Rui D S Prediger, Argelia E Rojas-Mayorquin, Aderbal S Aguiar, Caroline Chevarin, Raymond Mongeau, Michel Hamon, Laurence Lanfumey, Elaine Del Bel, Hisako Muramatsu, José Courty, Rita Raisman-Vozar. Mice with genetic deletion of the heparin-binding growth factor midkine exhibit early preclinical features of Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 118. issue 8. 2012-05-29. PMID:21301897. |
moreover, the genetic deletion of midkine decreased the expression of the enzyme tyrosine hydroxylase in the substantia nigra reducing partially the levels of dopamine and its metabolites in the olfactory bulb and striatum of mice. |
2012-05-29 |
2023-08-12 |
mouse |
| Sara Al-Sweidi, Marc Morissette, Mélanie Bourque, Thérèse Di Paol. Estrogen receptors and gonadal steroids in vulnerability and protection of dopamine neurons in a mouse model of Parkinson's disease. Neuropharmacology. vol 61. issue 4. 2012-05-25. PMID:21586296. |
we investigated the neuroprotective contribution of estrogen receptors (erα and erβ) against mptp toxicity by examining the membrane dopamine (da) transporter (dat), the vesicular monoamine transporter 2 (vmat2) and tyrosine hydroxylase (th) in er knock out (erko) c57bl/6 male mice compared to their plasma steroid levels. |
2012-05-25 |
2023-08-12 |
mouse |
| Hong Yang, Michael D Nyby, Yan Ao, Ai Chen, David W Adelson, Victoria Smutko, Janake Wijesuriya, Vay Liang W Go, Michael L Tuc. Role of brainstem thyrotropin-releasing hormone-triggered sympathetic overactivation in cardiovascular mortality in type 2 diabetic Goto-Kakizaki rats. Hypertension research : official journal of the Japanese Society of Hypertension. vol 35. issue 2. 2012-05-25. PMID:21900943. |
gk rats also had elevated basal plasma epinephrine, higher adrenal gene expression of tyrosine hydroxylase and dopamine β-hydroxylase (dβh), and greater plasma catecholamine and adrenal dβh responses to i.c. |
2012-05-25 |
2023-08-12 |
rat |
| Laure Chagniel, Christine Robitaille, Christopher Lacharité-Mueller, Geneviève Bureau, Michel Cy. Partial dopamine depletion in MPTP-treated mice differentially altered motor skill learning and action control. Behavioural brain research. vol 228. issue 1. 2012-05-24. PMID:22127145. |
severity of da-depletion was assessed by the evaluation of tyrosine hydroxylase (th) and dopamine transporter levels in the striatum using the western blot technique. |
2012-05-24 |
2023-08-12 |
mouse |
| Timothy South, Fred Westbrook, Margaret J Morri. Neurological and stress related effects of shifting obese rats from a palatable diet to chow and lean rats from chow to a palatable diet. Physiology & behavior. vol 105. issue 4. 2012-05-24. PMID:22155008. |
rats switched from chow to cafeteria diet (ch-caf) became hyperphagic and had increased dopamine d1, d2 and tyrosine hydroxylase mrna expression in the ventral tegmental area (vta) compared to rats switched from cafeteria to chow (caf-ch). |
2012-05-24 |
2023-08-12 |
rat |
| Jeffrey H Kordower, Hemraj B Dodiya, Adam M Kordower, Brian Terpstra, Katrina Paumier, Lalitha Madhavan, Caryl Sortwell, Kathy Steece-Collier, Timothy J Collie. Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat. Neurobiology of disease. vol 43. issue 3. 2012-05-21. PMID:21600984. |
double label immunohistochemistry combined with confocal microscopy revealed that a small number of grafted tyrosine hydroxylase (th) neurons (5.7% ± 1.5% (mean ± sem) of grafted dopamine cells) expressed host derived α synuclein but none of the grafted cells expressed host-derived gfp. |
2012-05-21 |
2023-08-12 |
human |
| X-Q Bao, X-C Kong, C Qian, D Zhan. FLZ protects dopaminergic neuron through activating protein kinase B/mammalian target of rapamycin pathway and inhibiting RTP801 expression in Parkinson's disease models. Neuroscience. vol 202. 2012-05-18. PMID:22138155. |
the beneficial effects of flz on motor behavior attributed to the elevation of dopamine level in striatum, tyrosine hydroxylase (th)-positive cells, and th activity in the middle brain of mouse. |
2012-05-18 |
2023-08-12 |
mouse |
| Teresa Femenía, Jorge Manzanare. Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission. Addiction biology. vol 17. issue 2. 2012-05-08. PMID:21966993. |
handling-induced convulsion (hic) associated to alcohol, alcohol-induced loss of righting reflex (lorr), hypothermic effects in response to acute ethanol challenge, blood ethanol levels (bels), conditioned place preference, voluntary ethanol consumption and preference, tyrosine hydroxylase (th), dopamine transporter (dat) and proenkephalin (penk) gene expression, and µ-, δ- and κ-opioid agonist-stimulated [s(35) ]- guanosine 5'-triphosphate-binding autoradiography were studied in prodynorphin knockout (pdyn ko) and wild-type (wt) mice. |
2012-05-08 |
2023-08-12 |
mouse |
| Michael F Salvatore, Brandon S Pruet. Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways. PloS one. vol 7. issue 1. 2012-05-08. PMID:22242182. |
dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways. |
2012-05-08 |
2023-08-12 |
rat |
| Natalia Gorelova, Patrick J Mulholland, L Judson Chandler, Jeremy K Seaman. The glutamatergic component of the mesocortical pathway emanating from different subregions of the ventral midbrain. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 2. 2012-05-07. PMID:21666135. |
in the present study, anterograde tracer injections into 4 ventral midbrain subregions were coupled with immunohistochemical analysis of labeled axons in pfc for markers of dopamine (da; tyrosine hydroxylase [th]) and glutamate (vesicular glutamate transporter 2; vglut2). |
2012-05-07 |
2023-08-12 |
Not clear |
| Renee L Good, Li-Ping Liang, Manisha Patel, Richard A Radcliff. Mouse strain- and age-dependent effects of binge methamphetamine on dopaminergic signaling. Neurotoxicology. vol 32. issue 6. 2012-05-02. PMID:21798282. |
here we further investigated the impact of genotype and age on tyrosine hydroxylase (th) loss and dopamine (da) metabolism due to a high binge dose of meth (4 × 5 mg/kg × 2 h × 2 days). |
2012-05-02 |
2023-08-12 |
mouse |
| Flora Klara Szabó, Wei-Wei Le, Natalie S Snyder, Gloria E Hoffma. Comparison of the temporal programs regulating tyrosine hydroxylase and enkephalin expressions in TIDA neurons of lactating rats following pup removal and then pup return. Journal of molecular neuroscience : MN. vol 45. issue 2. 2012-04-24. PMID:21125428. |
the aim of this experiment was to compare the effect of a brief interruption then resumption of suckling on the temporal program of tyrosine hydroxylase (th; rate-limiting enzyme of dopamine synthesis) and enk regulation in dams. |
2012-04-24 |
2023-08-12 |
rat |