| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Mitkovski, F E Padovan-Neto, R Raisman-Vozari, L Ginestet, C A da-Silva, E A Del-Be. Investigations into Potential Extrasynaptic Communication between the Dopaminergic and Nitrergic Systems. Frontiers in physiology. vol 3. 2012-10-12. PMID:23055978. |
the dual localization of immunoreactivity for nitric oxide synthase (nos) and tyrosine hydroxylase, enzymes responsible for the synthesis of nitric oxide and dopamine, respectively, was examined in neurons of the nigrostriatal pathway in the rat brain by means of a double-immunohistochemical method and confocal laser scanning microscopy, acquired at the resolution limit. |
2012-10-12 |
2023-08-12 |
rat |
| Dimitra Giannakopoulou, Véronique Daguin-Nerrière, Adamantia Mitsacos, Elias D Kouvelas, Isabelle Neveu, Panagiotis Giompres, Philippe Brache. Ectopic expression of TrKA in the adult rat basal ganglia induces both nerve growth factor-dependent and -independent neuronal responses. Journal of neuroscience research. vol 90. issue 8. 2012-10-05. PMID:22419059. |
nine weeks after transfer, tyrosine hydroxylase (th) and dopamine transporter (dat) mrnas were slightly decreased in the ipsilateral sn. |
2012-10-05 |
2023-08-12 |
rat |
| N Carkaci-Salli, S Battula, X Wang, J R Connor, K E Vran. Gender-specific regulation of tyrosine hydroxylase in thymocyte differentiation antigen-1 knockout mice. Journal of neuroscience research. vol 90. issue 8. 2012-10-05. PMID:22430860. |
in this study, we analyzed the activity and quantity of tyrosine hydroxylase (th; the rate-limiting enzyme in dopamine production) and determined phosphorylation levels for the enzyme phosphoserine-40 (pser-40). |
2012-10-05 |
2023-08-12 |
mouse |
| Narayan Ramakrishna, Harry C Meeker, Satyam Patel, Ted W Brown, Abdeslem El Idriss. Regulation of α-synuclein expression in Down syndrome. Journal of neuroscience research. vol 90. issue 8. 2012-10-05. PMID:22473712. |
we have also found increased levels of protein phosphatase 2a, a negative regulator of the activation of tyrosine hydroxylase and a key enzyme in the biosynthetic pathway for dopamine in ts65dn cortex. |
2012-10-05 |
2023-08-12 |
mouse |
| Hong Yuan, Li-Wu Liang, Zheng-Jing Chen, Hui-Ru Ji, Mei-Kang Wang, Hai-Ying Zhang, Cao Li, Jian-Yang X. R-apomorphine protects against 6-hydroxydopamine-induced nigrostriatal damage in rat. Neuroscience bulletin. vol 22. issue 6. 2012-10-02. PMID:17690718. |
structural and functional deficits were quantified by tyrosine hydroxylase (th) / nissl-staining cell number counting, striatal dopamine (da) content determination and amphetamine-induced rotation analysis. |
2012-10-02 |
2023-08-12 |
rat |
| J S Shin, S S Lee, M K Le. Inhibitory effects of noscapine on dopamine biosynthesis in PC12 cells. Archives of pharmacal research. vol 20. issue 5. 2012-10-02. PMID:18982500. |
the effects of noscapine, a phthalide isoquinoline alkaloid, on dopamine biosynthesis and tyrosine hydroxylase (th) activity in pc12 cells were investigated. |
2012-10-02 |
2023-08-12 |
Not clear |
| Y Shiotani, K L Jin, Y Kawai, H Kiyam. An electron microscopic immunocytochemical study on the tyrosine hydroxylase-positive, dopamine Beta-hydroxylase-negative cells in the pineal gland of golden hamsters. Journal of neuroendocrinology. vol 1. issue 6. 2012-10-02. PMID:19210411. |
abstract we have examined the ultrastructure of tyrosine hydroxylase-positive, dopamine beta-hydroxylase-negative neuron-like cells in the pineal gland of golden hamsters by electron microscopic immunocytochemistry using antiserum to tyrosine hydroxylase. |
2012-10-02 |
2023-08-12 |
Not clear |
| T Hökfelt, N Halasz, A Ljungdahl, O Johansson, M Goldstein, D Par. Histochemical support for a dopaminergic mechanism in the dendrites of certain periglomerular cells in the rat olfactory bulb. Neuroscience letters. vol 1. issue 2. 2012-10-02. PMID:19604758. |
both tyrosine hydroxylase and dopadecarboxylase, converting tyrosine to dopa and dopa to dopamine (da), respectively, but not dopamine-beta-hydroxylase, converting da to noradrenaline, are present in periglomerular cell bodies, as well as in their intraglomerular dendrites. |
2012-10-02 |
2023-08-12 |
rat |
| M Goedert, U Otten, H Thoene. Biochemical effects of nerve growth factor and its antibody on the vas defferens and the adrenal medulla. Neuroscience letters. vol 8. issue 1. 2012-10-02. PMID:19605152. |
the administration of nerve growth factor (ngf) to newborn and 30-day-old rats elicits a selective increase in tyrosine hydroxylase (th) and dopamine b-hydroxylase (dbh) activities both in the vas deferens and the adrenal medulla. |
2012-10-02 |
2023-08-12 |
rat |
| K Oka, G Ashiba, B Kiss, T Nagats. Short-term effect of stress on tyrosine hydroxylase activity. Neurochemistry international. vol 4. issue 5. 2012-10-02. PMID:20487890. |
for the in vivo assay, both the accumulation of dopa (tyrosine hydroxylase activity) and that of 5-hydroxytryptophan (tryptophan hydroxylase activity) and the levels of monoamines and the metabolites (noradrenalin, adrenalin, dopamine, normetanephrine, 3-methoxytyramine and serotonin) and those of precursor amino acids, tyrosine and tryptophan, were investigated in ten different brain regions and in adrenals. |
2012-10-02 |
2023-08-12 |
mouse |
| T Nagats. Biopterin cofactor and monoamine-synthesizing monooxygenases. Neurochemistry international. vol 5. issue 1. 2012-10-02. PMID:20487919. |
since tyrosine hydroxylase or tryptophan hydroxylase is the rate-limiting enzyme for the biosynthesis of catecholamines (dopamine, norepinephrine and epinephrine) or serotonin in monoaminergic neurons, biosynthesis of tetrahydrobiopterin from gtp may also regulate the tissue level of monoamine transmitters. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Puymira. Effects of dysthyroidism on central catecholaminergic neurons. Neurochemistry international. vol 7. issue 6. 2012-10-02. PMID:20493009. |
neonatal hypothyroidism induced either by (131)i or by an antithyroid drug decreases the concentration of dopamine, noradrenaline and the activity of tyrosine hydroxylase at least in whole brain studies. |
2012-10-02 |
2023-08-12 |
rat |
| J Antreassian, C Benlot, J Thibault, F Gros, H Gozlan, F Cesselin, J P Henry, J C Legran. Simultaneous evaluation of mRNAs of dopamine ?-hydroxylase, tyrosine hydroxylase and proenkephalin a from three human pheochromocytomas. Neurochemistry international. vol 8. issue 1. 2012-10-02. PMID:20493034. |
simultaneous evaluation of mrnas of dopamine ?-hydroxylase, tyrosine hydroxylase and proenkephalin a from three human pheochromocytomas. |
2012-10-02 |
2023-08-12 |
human |
| J Antreassian, C Benlot, J Thibault, F Gros, H Gozlan, F Cesselin, J P Henry, J C Legran. Simultaneous evaluation of mRNAs of dopamine ?-hydroxylase, tyrosine hydroxylase and proenkephalin a from three human pheochromocytomas. Neurochemistry international. vol 8. issue 1. 2012-10-02. PMID:20493034. |
using the rabbit reticulocyte cell-free translation system, the relative proportions of in vitro translatable mrnas of three proteins in three human pheochromocytomas: tyrosine hydroxylase (th), dopamine ?-hydroxylase (dbh) and proenkephalin a have been compared. |
2012-10-02 |
2023-08-12 |
human |
| A Härfstrand, K Fuxe, L F Agnati, P Eneroth, I Zini, M Zoli, K Andersson, G von Euler, L Terenius, V Mutt, M Goldstei. Studies on neuropeptide Y-catecholamine interactions in the hypothalamus and in the forebrain of the male rat. Relationship to neuroendocrine function. Neurochemistry international. vol 8. issue 3. 2012-10-02. PMID:20493065. |
(4) by means of the tyrosine hydroxylase inhibition method it was possible to show that acute intraventricular injection of npy (1.25 nmol) increased dopamine utilization in the medial and lateral palisade zone of the median eminence and in the anteromedial frontal cortex and reduced noradrenaline utilization in the parvocellular part of the paraventricular hypothalamic nucleus, while dopamine utilization was not influenced in the nucleus caudatus putamen, nucleus accumbens or in the tuberculum olfactorium. |
2012-10-02 |
2023-08-12 |
rat |
| K Fuxe, L F Agnati, K Andersson, A Cintra, A Härfstrand, M Zoli, P Eneroth, M Goldstei. D1 receptor mechanisms in the median eminence and their inhibitory regulation of LHRH release. Neurochemistry international. vol 13. issue 2. 2012-10-02. PMID:20501286. |
d1 receptor mechanisms in the median eminence have been studied by means of immunocytochemistry using antisera against dopamine and cyclic amp-regulated phosphoprotein-32 (darpp-32) and tyrosine hydroxylase (th) and by autoradiography using the iodinated analogue of the d1 receptor antagonist sch-23390. |
2012-10-02 |
2023-08-12 |
rat |
| K Fuxe, A Cintra, L F Agnati, A Härfstrand, M Goldstei. Studies on the relationship of tyrosine hydroxylase, dopamine and cyclic amp-regulated phosphoprotein-32 immunoreactive neuronal structures and d1 receptor antagonist binding sites in various brain regions of the male rat-mismatches indicate a role of d1 receptors in volume transmission. Neurochemistry international. vol 13. issue 2. 2012-10-02. PMID:20501287. |
studies on the relationship of tyrosine hydroxylase, dopamine and cyclic amp-regulated phosphoprotein-32 immunoreactive neuronal structures and d1 receptor antagonist binding sites in various brain regions of the male rat-mismatches indicate a role of d1 receptors in volume transmission. |
2012-10-02 |
2023-08-12 |
rat |
| K Fuxe, A Cintra, L F Agnati, A Härfstrand, M Goldstei. Studies on the relationship of tyrosine hydroxylase, dopamine and cyclic amp-regulated phosphoprotein-32 immunoreactive neuronal structures and d1 receptor antagonist binding sites in various brain regions of the male rat-mismatches indicate a role of d1 receptors in volume transmission. Neurochemistry international. vol 13. issue 2. 2012-10-02. PMID:20501287. |
the relationship between tyrosine hydroxylase (th), dopamine (da) and cyclic amp-regulated phosphoprotein-32 (darpp-32) immunoreactive (ir) neuronal structures and d1 receptor antagonist binding sites has been analysed in various brain regions in the male rat, using immunocytochemistry and receptor autoradiography with the iodinated analogue of sch 23390 ([(125)i]sch 23982) as radioligand. |
2012-10-02 |
2023-08-12 |
rat |
| M Hagihara, K Fujishiro, A Takahashi, M Naoi, T Nagats. Cyclosporin A, an immune suppressor, enhanced neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mice. Neurochemistry international. vol 15. issue 2. 2012-10-02. PMID:20504491. |
tyrosine hydroxylase activity and dopamine content in striatum and hypothalamus were reduced markedly, and the reduction was more manifest in the striatum. |
2012-10-02 |
2023-08-12 |
mouse |
| M Hagihara, K Fujishiro, A Takahashi, M Naoi, T Nagats. Cyclosporin A, an immune suppressor, enhanced neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mice. Neurochemistry international. vol 15. issue 2. 2012-10-02. PMID:20504491. |
in addition, dopamine and biopterin contents in the striatum decreased quite in parallel to the reduction of tyrosine hydroxylase activity. |
2012-10-02 |
2023-08-12 |
mouse |