| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Sorriento, Gaetano Santulli, Carmine Del Giudice, Antonio Anastasio, Bruno Trimarco, Guido Iaccarin. Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo. Hypertension (Dallas, Tex. : 1979). vol 60. issue 1. 2012-09-07. PMID:22665130. |
we demonstrated that genes coding for tyrosine hydroxylase, dopa decarboxylase, dopamine β hydroxylase (dβh), and phenylethanolamine-n-methyl transferase, enzymes involved in the synthesis of catecholamines, are all expressed in basal conditions in bovine aorta ecs, and their expression is enhanced in response to hypoxia. |
2012-09-07 |
2023-08-12 |
mouse |
| Yuhong Fu, Yuan Yuan, Glenda Halliday, Zoltán Rusznák, Charles Watson, George Paxino. A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse. Brain structure & function. vol 217. issue 2. 2012-09-04. PMID:21935672. |
the dopamine neuron groups were analysed in 15 adult c57bl/6j mice by anatomically localising tyrosine hydroxylase (th), dopamine transporter protein (dat), calbindin, and the g-protein-activated inward rectifier potassium channel 2 (girk2) proteins. |
2012-09-04 |
2023-08-12 |
mouse |
| Shyam Sunder Agrawal, Sumeet Gullaiya, Vishal Dubey, Varun Singh, Ashok Kumar, Ashish Nagar, Poonam Tiwar. Neurodegenerative Shielding by Curcumin and Its Derivatives on Brain Lesions Induced by 6-OHDA Model of Parkinson's Disease in Albino Wistar Rats. Cardiovascular psychiatry and neurology. vol 2012. 2012-08-30. PMID:22928089. |
the behavioral observations, biochemical markers, quantification of dopamine (da), dopac, and hva followed by dopamine (d(2)) receptor binding assay and tyrosine hydroxylase (th, using immunohistochemistry) were evaluated using hplc after three weeks of lesion. |
2012-08-30 |
2023-08-12 |
rat |
| Margaret Chia-Ying Wey, Elizabeth Fernandez, Paul Anthony Martinez, Patricia Sullivan, David S Goldstein, Randy Stron. Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease. PloS one. vol 7. issue 2. 2012-08-27. PMID:22384032. |
we observed a significant loss of neurons immunoreactive for tyrosine hydroxylase (th) in the substantia nigra and a reduction of dopamine and metabolites in the striatum of aldh1a1(-/-)×aldh2(-/-) mice. |
2012-08-27 |
2023-08-12 |
mouse |
| Zaher Arraf, Tamar Amit, Moussa B H Youdim, Raymond Fara. Lithium and oxidative stress lessons from the MPTP model of Parkinson's disease. Neuroscience letters. vol 516. issue 1. 2012-08-24. PMID:22480690. |
from analyzing the pattern of protection in various parameters, we suggest that lithium protects against mptp-induced depletion of striatal dopamine (da) by preventing free radical-induced inactivation of tyrosine hydroxylase (th), the rate limiting enzyme in dopamine synthesis. |
2012-08-24 |
2023-08-12 |
mouse |
| Akiko Muroyama, Aya Fujita, Cheng Lv, Shota Kobayashi, Yoshiyasu Fukuyama, Yasuhide Mitsumot. Magnolol Protects against MPTP/MPP(+)-Induced Toxicity via Inhibition of Oxidative Stress in In Vivo and In Vitro Models of Parkinson's Disease. Parkinson's disease. vol 2012. 2012-08-23. PMID:22655218. |
western blot analysis revealed that mptp injections substantially decreased protein levels of dopamine transporter (dat) and tyrosine hydroxylase (th) and increased glial fibrillary acidic protein (gfap) levels in the striatum. |
2012-08-23 |
2023-08-12 |
mouse |
| Diana Lelidett Lourenco-Jaramillo, Ana María Sifuentes-Rincón, Gaspar Manuel Parra-Bracamonte, Xochitl Fabiola de la Rosa-Reyna, Aldo Segura-Cabrera, Williams Arellano-Ver. Genetic diversity of tyrosine hydroxylase (TH) and dopamine β-hydroxylase (DBH) genes in cattle breeds. Genetics and molecular biology. vol 35. issue 2. 2012-08-23. PMID:22888292. |
genetic diversity of tyrosine hydroxylase (th) and dopamine β-hydroxylase (dbh) genes in cattle breeds. |
2012-08-23 |
2023-08-12 |
cattle |
| Diana Lelidett Lourenco-Jaramillo, Ana María Sifuentes-Rincón, Gaspar Manuel Parra-Bracamonte, Xochitl Fabiola de la Rosa-Reyna, Aldo Segura-Cabrera, Williams Arellano-Ver. Genetic diversity of tyrosine hydroxylase (TH) and dopamine β-hydroxylase (DBH) genes in cattle breeds. Genetics and molecular biology. vol 35. issue 2. 2012-08-23. PMID:22888292. |
dna from four cattle breeds was used to re-sequence all of the exons and 56% of the introns of the bovine tyrosine hydroxylase (th) gene and 97% and 13% of the bovine dopamine β-hydroxylase (dbh) coding and non-coding sequences, respectively. |
2012-08-23 |
2023-08-12 |
cattle |
| Jun Wang, Hong Jiang, Jun-Xia Xi. [Correlation between iron levels and degeneration of dopaminergic neurons in rat nigrostriatal system during the early 6-OHDA lesions in medial forebrain bundle]. Sheng li xue bao : [Acta physiologica Sinica]. vol 55. issue 4. 2012-08-16. PMID:12937822. |
the results showed that 1 d or 3 d after lesions in mfb, there was a 45% or 66% reduction, respectively, in the density of tyrosine hydroxylase (th) immunoreactive cells in the substantia nigra (sn) of the lesioned side accompanied by an increase in iron staining intensity and iron concentration; while there was no change in dopamine (da) release in the striatum (str) of the lesioned side compared with the unlesioned side and the normal rats. |
2012-08-16 |
2023-08-12 |
rat |
| Mustafa Varcin, Eduard Bentea, Birgit Mertens, Chris Van Den Haute, Veerle Baekelandt, Yvette Michotte, Sophie Sarr. Acute versus long-term effects of 6-hydroxydopamine on oxidative stress and dopamine depletion in the striatum of mice. Journal of neuroscience methods. vol 202. issue 2. 2012-08-16. PMID:21782850. |
three weeks after the local 6-ohda perfusion, the total striatal dopamine (da) and dihydroxyphenylacetic acid (dopac) content were reduced by 30%, compared to the intact striatum, accompanied by a reduction in striatal tyrosine hydroxylase (th) immunoreactive (ir) nerve terminals. |
2012-08-16 |
2023-08-12 |
mouse |
| Simon Allard, Varin Gosein, A Claudio Cuello, A Ribeiro-da-Silv. Changes with aging in the dopaminergic and noradrenergic innervation of rat neocortex. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:20096955. |
following the behavioral characterization, the animals were sacrificed and the cortical tissue was processed for immunofluorescence using antibodies directed against tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) to detect and discriminate noradrenergic and dopaminergic varicosities. |
2012-08-08 |
2023-08-12 |
rat |
| Yuh-Lih Chang, Shih-Jen Chen, Chung-Lan Kao, Shih-Chieh Hung, Dah-Ching Ding, Cheng-Chia Yu, Yi-Jen Chen, Hung-Hai Ku, Chin-Po Lin, Kun-Hsiung Lee, Yu-Chih Chen, Jhi-Joung Wang, Chuan-Chih Hsu, Liang-Kung Chen, Hsin-Yang Li, Shih-Hwa Chio. Docosahexaenoic acid promotes dopaminergic differentiation in induced pluripotent stem cells and inhibits teratoma formation in rats with Parkinson-like pathology. Cell transplantation. vol 21. issue 1. 2012-08-01. PMID:21669041. |
dha treatment facilitated ips differentiation into tyrosine hydroxylase (th)-positive neurons in vitro and in vivo and functionally increased dopamine release in transplanted grafts in pd-like animals. |
2012-08-01 |
2023-08-12 |
rat |
| Yukio Ago, Toshiyuki Kawasaki, Tetsuaki Nashida, Yuki Ota, Yana Cong, Mari Kitamoto, Teisuke Takahashi, Kazuhiro Takuma, Toshio Matsud. SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21903118. |
sea0400 protected against the dopaminergic neurotoxicity (determined by dopamine levels in the midbrain and striatum, tyrosine hydroxylase immunoreactivity in the substantia nigra and striatum, striatal dopamine release, and motor deficits) in mptp-treated mice. |
2012-08-01 |
2023-08-12 |
mouse |
| A Bartalucci, M Ferrucci, F Fulceri, G Lazzeri, P Lenzi, L Toti, F R Serpiello, A La Torre, M Ges. High-intensity exercise training produces morphological and biochemical changes in adrenal gland of mice. Histology and histopathology. vol 27. issue 6. 2012-07-30. PMID:22473696. |
in the adrenal medulla, despite the absence of morphological changes, immunohistochemistry for tyrosine hydroxylase, dopamine β-hydroxylase and phenyl-ethanolamine-n-methyltransferase demonstrated an increased immunopositivity for these cathecolamine-synthesizing enzymes after intense exercise. |
2012-07-30 |
2023-08-12 |
mouse |
| Carmela M Reichel, Lauren A Ramsey, Marek Schwendt, Jacqueline F McGinty, Ronald E Se. Methamphetamine-induced changes in the object recognition memory circuit. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22115899. |
in addition, striatal dopamine transporters, tyrosine hydroxylase, and glial fibrillary acidic protein were measured to assess potential neurotoxicity. |
2012-07-27 |
2023-08-12 |
human |
| Peternella S Verhave, Marjan J Jongsma, Roland M Van Den Berg, Raymond A P Vanwersch, August B Smit, Ingrid H C H M Philippen. Neuroprotective effects of riluzole in early phase Parkinson's disease on clinically relevant parameters in the marmoset MPTP model. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22178201. |
at three weeks following the last mptp challenge, brains were dissected and dopamine levels in the striatum and the tyrosine hydroxylase (th) expressing dopamine (da) neurons in the substantia nigra (sn) were compared. |
2012-07-27 |
2023-08-12 |
monkey |
| Manoj A Upadhya, Kartik T Nakhate, Dadasaheb M Kokare, Uday Singh, Praful S Singru, Nishikant K Subheda. CART peptide in the nucleus accumbens shell acts downstream to dopamine and mediates the reward and reinforcement actions of morphine. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22186082. |
several tyrosine hydroxylase (marker for dopamine) immunoreactive fibers were seen contacting cart neurons in the acbsh. |
2012-07-27 |
2023-08-12 |
Not clear |
| Samuel S Shin, Eric R Bray, C Edward Dixo. Effects of nicotine administration on striatal dopamine signaling after traumatic brain injury in rats. Journal of neurotrauma. vol 29. issue 5. 2012-07-23. PMID:21815786. |
in order to reverse deficits in the activity of tyrosine hydroxylase and dopamine release following tbi, we administered nicotine by intraperitoneal injection into rats for 7 days. |
2012-07-23 |
2023-08-12 |
rat |
| Luisa Rocha, Mario Alonso-Vanegas, Juana Villeda-Hernández, Mario Mújica, José Miguel Cisneros-Franco, Mario López-Gómez, Cecilia Zavala-Tecuapetla, Christian Lizette Frías-Soria, José Segovia-Vila, Anna Borsod. Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21964255. |
specifically, we investigated changes in dopamine and its metabolites, d1 and d2 receptors, tyrosine hydroxylase (th) and dopamine transporter. |
2012-07-23 |
2023-08-12 |
Not clear |
| M Bousquet, I St-Amour, M Vandal, P Julien, F Cicchetti, F Calo. High-fat diet exacerbates MPTP-induced dopaminergic degeneration in mice. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21971528. |
as expected, the mptp treatment produced nigral dopaminergic degeneration as evidenced by the loss of striatal dopamine and the decreased number of nigral tyrosine hydroxylase (th)- and dopamine transporter-expressing neurons (23% and 25%, respectively). |
2012-07-23 |
2023-08-12 |
mouse |