| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Subramanian Mariappan, Wieslaw Bogdanowicz, Hanumanthan Raghuram, Ganapathy Marimuthu, Koilmani Emmanuvel Raja. Structure of distress call: implication for specificity and activation of dopaminergic system. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 202. issue 1. 2016-09-27. PMID:26610332. |
we subsequently found that tyrosine hydroxylase (th) and its transcription factor-nuclear receptor related factor 1 (nurr-1); and the dopamine transporter (dat) and its receptor (d1dr) were elevated significantly in the amygdala of bats both emitting and responding to a distress call, but not in the case of bats responding to the modified call. |
2016-09-27 |
2023-08-13 |
Not clear |
| Annmarie Ramkissoon, Peter G Well. Methamphetamine oxidative stress, neurotoxicity, and functional deficits are modulated by nuclear factor-E2-related factor 2. Free radical biology & medicine. vol 89. 2016-09-22. PMID:26427884. |
multiple-day dosing with meth enhanced dna oxidation and decreased tyrosine hydroxylase and dopamine transporter staining in the striatum, indicating dopaminergic nerve terminal toxicity, which was more severe in -/- mice, as were deficits in motor coordination and olfactory discrimination. |
2016-09-22 |
2023-08-13 |
mouse |
| Cheng-You Zheng, Bao-Jian Guo, Wei Cai, Wei Cui, Shing-Hung Mak, Yu-Qiang Wang, Simon Ming-Yuen Lee, Yi-Fan Han, Zai-Jun Zhan. No synergism between bis(propyl)-cognitin and rasagiline on protecting dopaminergic neurons in Parkinson's disease mice. Neural regeneration research. vol 11. issue 8. 2016-09-21. PMID:27651784. |
by using neurobehavioural tests, high-performance liquid chromatography and western blot assay, we showed that b3c at 0.3 mg/kg, rasagiline at 0.02 mg/kg, as well as co-treatment with b3c and rasagiline prevented mptp-induced behavioural abnormities, increased the concentrations of dopamine and its metabolites in the striatum, and up-regulated the expression of tyrosine hydroxylase in the substantia nigra. |
2016-09-21 |
2023-08-13 |
mouse |
| R J Torres, J G Pui. Hypoxanthine deregulates genes involved in early neuronal development. Implications in Lesch-Nyhan disease pathogenesis. Journal of inherited metabolic disease. vol 38. issue 6. 2016-09-20. PMID:25940910. |
hypoxanthine effects on ra-differentiation were examined by the changes on the expression of various transcription factor genes essential to neuronal differentiation and by the changes in tyrosine hydroxylase (th), dopamine, adenosine and serotonin receptors (drd, adora, htr). |
2016-09-20 |
2023-08-13 |
human |
| Christina D'Arcy, Joe E Luevano, Manuel Miranda-Arango, Joseph A Pipkin, Jonathan A Jackson, Eddie Castañeda, Kristin L Gosselink, Laura E O'Del. Extended access to methamphetamine self-administration up-regulates dopamine transporter levels 72 hours after withdrawal in rats. Behavioural brain research. vol 296. 2016-09-15. PMID:26367473. |
this study examined changes in striatal dopamine transporter (dat), tyrosine hydroxylase (th) and dopamine receptor 2 (d2) 72 h after withdrawal from meth intravenous self- administration (ivsa). |
2016-09-15 |
2023-08-13 |
rat |
| Katarzyna Palus, Jarosław Całk. Alterations of neurochemical expression of the coeliac-superior mesenteric ganglion complex (CSMG) neurons supplying the prepyloric region of the porcine stomach following partial stomach resection. Journal of chemical neuroanatomy. vol 72. 2016-09-13. PMID:26730724. |
in control animals, retrograde-labelled perikarya were immunoreactive to tyrosine hydroxylase (th), dopamine β-hydroxylase (dβh), neuropeptide y (npy) and galanin (gal). |
2016-09-13 |
2023-08-13 |
Not clear |
| Jun Wakai, Anna Takayama, Takuya Yokoyama, Nobuaki Nakamuta, Tatsumi Kusakabe, Yoshio Yamamot. Immunohistochemical localization of dopamine D2 receptor in the rat carotid body. Acta histochemica. vol 117. issue 8. 2016-09-07. PMID:26272445. |
d2r immunoreactivity was mainly localized in glomus cells immunoreactive to tyrosine hydroxylase or dopamine β-hydroxylase (dbh), but not in s100b-immunoreactive sustentacular cells. |
2016-09-07 |
2023-08-13 |
rat |
| Emily Hensleigh, Laurel M Pritchar. Maternal separation increases methamphetamine-induced damage in the striatum in male, but not female rats. Behavioural brain research. vol 295. 2016-09-05. PMID:25535855. |
seven days after treatment, rats were euthanized and striatum was collected for quantification of tyrosine hydroxylase (th) and dopamine transporters (dat) content by western blot. |
2016-09-05 |
2023-08-13 |
rat |
| Sachchida Nand Rai, Satyndra Kumar Yadav, Divakar Singh, Surya Pratap Sing. Ursolic acid attenuates oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in MPTP-induced Parkinsonian mouse model. Journal of chemical neuroanatomy. vol 71. 2016-09-01. PMID:26686287. |
tyrosine hydroxylase (th) immunostaining of sn dopaminergic neurons as well as hplc quantification of dopamine and its metabolites 3,4-dihydroxyphenylacetic acid (dopac) and homovanilic acid (hva) were also performed. |
2016-09-01 |
2023-08-13 |
mouse |
| Goichi Beck, Koei Shinzawa, Hideki Hayakawa, Kousuke Baba, Hisae Sumi-Akamaru, Yoshihide Tsujimoto, Hideki Mochizuk. Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A2β Knockout Mice. PloS one. vol 11. issue 4. 2016-09-01. PMID:27078024. |
at all clinical stages, nerve terminals in the striatum were immunopositive for tyrosine hydroxylase (th) and dopamine transporter (dat) in wild-type (wt) control mice. |
2016-09-01 |
2023-08-13 |
mouse |
| Sonal Agrawal, Anubhuti Dixit, Ashish Singh, Pratibha Tripathi, Dhirendra Singh, Devendra Kumar Patel, Mahendra Pratap Sing. Cyclosporine A and MnTMPyP Alleviate α-Synuclein Expression and Aggregation in Cypermethrin-Induced Parkinsonism. Molecular neurobiology. vol 52. issue 3. 2016-08-30. PMID:25370934. |
the expression of α-synuclein, 3-nitrotyrosine (3-nt), 4-hydroxynonenal (4-hne)-modified proteins, mitochondrial dysfunction-dependent apoptotic proteins, nitrite content, lipid peroxidation (lpo) and number of tyrosine hydroxylase (th)-positive neurons were estimated in the substantia nigra and dopamine content in the striatum of control and treated rats employing standard procedures. |
2016-08-30 |
2023-08-13 |
rat |
| WeiZhen Liu, Yanwei Li, Jaishree Jalewa, Taylor Saunders-Wood, Lin Li, Christian Hölsche. Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease. European journal of pharmacology. vol 765. 2016-08-12. PMID:26302060. |
oxy treatment prevented or reversed the mptp- induced motor impairment (rotarod, spontaneous locomotion, swim activity, muscle strength test), the mptp-induced reduction in tyrosine hydroxylase (th) levels (dopamine synthesis) in the substantia nigra and basal ganglia, the reduction of the synaptic marker synapstophysin, the inactivation of the growth factor kinase akt/pkb and of the anti-apoptotic signaling molecule bcl-2, and the increase of levels of the pro-inflammatory cytokine tnf-α. |
2016-08-12 |
2023-08-13 |
mouse |
| Bryan A Killinger, Anna Moszczynsk. Epothilone D prevents binge methamphetamine-mediated loss of striatal dopaminergic markers. Journal of neurochemistry. vol 136. issue 3. 2016-08-05. PMID:26465779. |
exposure to binge methamphetamine (meth) can result in a permanent or transient loss of dopaminergic (daergic) markers such as dopamine (da), dopamine transporter, and tyrosine hydroxylase (th) in the striatum. |
2016-08-05 |
2023-08-13 |
rat |
| Weibin Qian, Xinrui Cai, Yingying Wang, Xinying Zhang, Hongmin Zhao, Qiuhai Qian, Zhihong Yang, Zhantao Liu, Junichi Hasegaw. Effect of Gingerol on Cisplatin-Induced Pica Analogous to Emesis Via Modulating Expressions of Dopamine 2 Receptor, Dopamine Transporter and Tyrosine Hydroxylase in the Vomiting Model of Rats. Yonago acta medica. vol 59. issue 2. 2016-08-05. PMID:27493480. |
effect of gingerol on cisplatin-induced pica analogous to emesis via modulating expressions of dopamine 2 receptor, dopamine transporter and tyrosine hydroxylase in the vomiting model of rats. |
2016-08-05 |
2023-08-13 |
rat |
| Weibin Qian, Xinrui Cai, Yingying Wang, Xinying Zhang, Hongmin Zhao, Qiuhai Qian, Zhihong Yang, Zhantao Liu, Junichi Hasegaw. Effect of Gingerol on Cisplatin-Induced Pica Analogous to Emesis Via Modulating Expressions of Dopamine 2 Receptor, Dopamine Transporter and Tyrosine Hydroxylase in the Vomiting Model of Rats. Yonago acta medica. vol 59. issue 2. 2016-08-05. PMID:27493480. |
we are going to investigate the mechanisms of inhibitive effect of gingerol on cisplatin-induced pica behaviour by studying on both peripheral and central levels, and the effects of gingerol on homeostasis of dopamine (da) transmission: dopamine d2 receptor (d2r), dopamine transporter (dat) and tyrosine hydroxylase (th). |
2016-08-05 |
2023-08-13 |
rat |
| Jun-Jun Zhou, Shen-Yu Zhai, Hui-Nan Zhang, Yue-Hua Wang, Xiao-Ping P. Neuroprotective effects of 3-O-demethylswertipunicoside against MPTP-induced Parkinson's disease in vivo and its antioxidant properties in vitro. Brain research. vol 1624. 2016-08-04. PMID:26210618. |
in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (mptp)-treated mouse model of parkinson's disease (pd), 3-ods dose-dependently improved motor coordination (as shown by rotarod test), increased the contents of dopamine (da) and its metabolites in the striatum, and increased the number of tyrosine hydroxylase (th)-positive neurons in the substantia nigra (sn). |
2016-08-04 |
2023-08-13 |
mouse |
| Zhirui Guo, Shasha Xu, Na Du, Jia Liu, Yiyun Huang, Mei Ha. Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system. Neuroscience letters. vol 616. 2016-08-04. PMID:26827716. |
tyrosine hydroxylase (th) and dopamine transporter (dat) levels were detected by immunohistochemistry method. |
2016-08-04 |
2023-08-13 |
mouse |
| Yueting Shao, Hing Man Cha. Effects of methylmercury on dopamine release in MN9D neuronal cells. Toxicology mechanisms and methods. vol 25. issue 8. 2016-08-03. PMID:26056851. |
at the same time, both mehg and mpp+ decreased the synthesis of tyrosine hydroxylase and dopamine transporter at the mrna and protein levels. |
2016-08-03 |
2023-08-13 |
Not clear |
| R W Morris, T D Purves-Tyson, C Shannon Weickert, D Rothmond, R Lenroot, T W Weicker. Testosterone and reward prediction-errors in healthy men and men with schizophrenia. Schizophrenia research. vol 168. issue 3. 2016-08-03. PMID:26232868. |
we also identified midbrain dopamine neurons that were androgen receptor immunoreactive, and found that androgen receptor (ar) mrna was positively correlated with tyrosine hydroxylase (th) mrna in human male substantia nigra. |
2016-08-03 |
2023-08-13 |
human |
| M M Sidor, S M Spencer, K Dzirasa, P K Parekh, K M Tye, M R Warden, R N Arey, J F Enwright, J P R Jacobsen, S Kumar, E M Remillard, M G Caron, K Deisseroth, C A McClun. Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice. Molecular psychiatry. vol 20. issue 11. 2016-08-02. PMID:25560763. |
mood-cycling coincides with abnormal daytime spikes in ventral tegmental area (vta) dopaminergic activity, tyrosine hydroxylase (th) levels and dopamine synthesis. |
2016-08-02 |
2023-08-13 |
mouse |