| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhan-Ying Hu, Jing-Pu Zhan. [Effect of beclin1 on vincristine-induced dopaminergic neurons injury in zebrafish]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 6. 2016-02-02. PMID:25212030. |
the results showed that the transcription levels of tyrosine hydroxylase gene and dopamine transporter protein gene were inhibited. |
2016-02-02 |
2023-08-13 |
zebrafish |
| Alexander A Nevue, Cameron J Elde, David J Perkel, Christine V Portfor. Dopaminergic Input to the Inferior Colliculus in Mice. Frontiers in neuroanatomy. vol 9. 2016-02-02. PMID:26834578. |
the principal auditory midbrain nucleus, the inferior colliculus (ic), is a likely location for dopaminergic modulation of auditory processing because it contains dopamine receptors and nerve terminals immunoreactive for tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine synthesis. |
2016-02-02 |
2023-08-13 |
mouse |
| Beatrice Macchi, Rosanna Di Paola, Francesca Marino-Merlo, Maria Rosa Felice, Salvatore Cuzzocrea, Antonio Mastin. Inflammatory and cell death pathways in brain and peripheral blood in Parkinson's disease. CNS & neurological disorders drug targets. vol 14. issue 3. 2016-02-01. PMID:25714978. |
regarding the peripheral blood, reduced amounts of dopamine, reduced levels of immunoreactivity for tyrosine hydroxylase and dopamine active transporter, and alterations of dopamine receptor expression have been detected in mononuclear cells from pd patients. |
2016-02-01 |
2023-08-13 |
Not clear |
| Xiao-Feng Yin, Hua-Min Xu, Yun-Xia Jiang, Yun-Lai Zhi, Yu-Xiu Liu, Heng-Wei Xiang, Kai Liu, Xiao-Dong Ding, Peng Su. Lentivirus-mediated Persephin over-expression in Parkinson's disease rats. Neural regeneration research. vol 10. issue 11. 2016-01-25. PMID:26807117. |
results found that the number of dopaminergic neurons in the substantia nigra increased, tyrosine hydroxylase expression was upregulated and concentrations of dopamine and its metabolites in corpus striatum were increased after pretreatment with persephin gene. |
2016-01-25 |
2023-08-13 |
rat |
| Reena Haobam, Debasmita Tripathy, Navneet A Kaidery, Kochupurackal P Mohanakuma. Embryonic stem cells derived neuron transplantation recovery in models of parkinsonism in relation to severity of the disorder in rats. Rejuvenation research. vol 18. issue 2. 2016-01-22. PMID:25546608. |
the severity of the disease was determined using the number of amphetamine- or apomorphine-induced rotations, striatal dopamine levels as estimated by high-performance liquid chromatography (hplc)-electrochemistry, and the number of surviving tyrosine hydroxylase immunoreactive dopaminergic neurons in the substantia nigra pars compacta. |
2016-01-22 |
2023-08-13 |
rat |
| Xiu-Qi Bao, Liang-Yu Wu, Xiao-Liang Wang, Hua Sun, Dan Zhan. Squamosamide derivative FLZ protected tyrosine hydroxylase function in a chronic MPTP/probenecid mouse model of Parkinson's disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 388. issue 5. 2016-01-19. PMID:25678053. |
the beneficial effects of flz attributed to the elevation of dopaminergic neuron number, dopamine level, and tyrosine hydroxylase (th) activity, as well as decrease of α-synuclein (α-syn) expression, α-syn phosphorylation, nitration, and aggregation. |
2016-01-19 |
2023-08-13 |
mouse |
| Sebastián Hormigo, Ricardo Gómez-Nieto, Orlando Castellano, M Javier Herrero-Turrión, Dolores E López, José de Anchieta de Castro E Horta-Júnio. The noradrenergic projection from the locus coeruleus to the cochlear root neurons in rats. Brain structure & function. vol 220. issue 3. 2016-01-15. PMID:24623157. |
using light and confocal microscopy, we show a strong immunoreactivity for tyrosine hydroxylase and dopamine β-hydroxylase in these terminals, indicating noradrenaline release. |
2016-01-15 |
2023-08-12 |
rat |
| Trayambak Pathak, Tarjani Agrawal, Shlesha Richhariya, Sufia Sadaf, Gaiti Hasa. Store-Operated Calcium Entry through Orai Is Required for Transcriptional Maturation of the Flight Circuit in Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 40. 2016-01-13. PMID:26446229. |
the loss of orai-mediated soce alters transcriptional regulation of dopaminergic neurons, leading to downregulation of the enzyme tyrosine hydroxylase, which is essential for dopamine synthesis, and the dopamine transporter, which is required for dopamine uptake after synaptic release. |
2016-01-13 |
2023-08-13 |
drosophila_melanogaster |
| Bo Wang, Yani Li, Ruiyong Wu, Shuwei Zhang, Fadao Ta. Behavioral responses to pups in males with different reproductive experiences are associated with changes in central OT, TH and OTR, D1R, D2R mRNA expression in mandarin voles. Hormones and behavior. vol 67. 2016-01-12. PMID:25496756. |
central levels of neuropeptide oxytocin (ot), tyrosine hydroxylase (th), as well as oxytocin receptor (otr), dopamine 1-type receptor (d1r) and dopamine 2-type receptor (d2r) mrna expression in the nucleus accumbens and medial amygdala were also measured in these males. |
2016-01-12 |
2023-08-13 |
Not clear |
| Victoria P Connaughton, Bradley Wetzell, Lynne S Arneson, Vittoria DeLucia, Anthony L Rile. Elevated dopamine concentration in light-adapted zebrafish retinas is correlated with increased dopamine synthesis and metabolism. Journal of neurochemistry. vol 135. issue 1. 2016-01-08. PMID:26212704. |
this increase is correlated with an increase in both tyrosine hydroxylase (th) and dopac (3,4-dihydroxyphenylacetic acid), suggesting that changes in dopamine concentration are due to light-adaptive changes in the synthesis, release and metabolism of dopamine. |
2016-01-08 |
2023-08-13 |
zebrafish |
| Jazmin E Hawes, Dijana Tesic, Andrew J Whitehouse, Graeme R Zosky, Jeremy T Smith, Caitlin S Wyrwol. Maternal vitamin D deficiency alters fetal brain development in the BALB/c mouse. Behavioural brain research. vol 286. 2016-01-04. PMID:25753408. |
at e17.5, brain tyrosine hydroxylase (th) gene expression was reduced in females, as was th protein localization (to identify dopamine neurons) in the substantia nigra of vitamin d-deficient female foetuses. |
2016-01-04 |
2023-08-13 |
mouse |
| Rita Gálosi, Andras Hajnal, Zoltán Petykó, Géza Hartmann, Zoltán Karádi, László Lénár. The role of catecholamine innervation in the medial prefrontal cortex on the regulation of body weight and food intake. Behavioural brain research. vol 286. 2016-01-04. PMID:25783808. |
dopamine (da) and ne content, as well as, tyrosine hydroxylase immunoreactivity were assessed to confirm the neurotoxic effect of treatments. |
2016-01-04 |
2023-08-13 |
Not clear |
| Alessandro Pristerà, Wei Lin, Anna-Kristin Kaufmann, Katherine R Brimblecombe, Sarah Threlfell, Paul D Dodson, Peter J Magill, Cathy Fernandes, Stephanie J Cragg, Siew-Lan An. Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 35. 2016-01-04. PMID:26283356. |
we show that deletion of foxa1/2 results in down-regulation of tyrosine hydroxylase, the rate-limiting enzyme of dopamine (da) biosynthesis, specifically in dopaminergic neurons of the substantia nigra pars compacta (snc). |
2016-01-04 |
2023-08-13 |
mouse |
| Sussy Bastías-Candia, Manuela Di Benedetto, Claudio D'Addario, Sanzio Candeletti, Patrizia Romuald. Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ-NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease. Environmental toxicology. vol 30. issue 6. 2015-12-15. PMID:24376148. |
our results showed that after paraquat/maneb (5/15 mg kg(-1) ) treatment, a significant reduction in tyrosine hydroxylase (th) levels, the rate-limiting enzyme for dopamine synthesis, was observed. |
2015-12-15 |
2023-08-12 |
rat |
| Juhee Lim, Hyo-In Kim, Yeojin Bang, Wongi Seol, Hueng-Sik Choi, Hyun Jin Cho. Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter by nuclear receptor ERRγ in SH-SY5Y cells. Neuroreport. vol 26. issue 6. 2015-12-14. PMID:25807177. |
hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter by nuclear receptor errγ in sh-sy5y cells. |
2015-12-14 |
2023-08-13 |
Not clear |
| Juhee Lim, Hyo-In Kim, Yeojin Bang, Wongi Seol, Hueng-Sik Choi, Hyun Jin Cho. Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter by nuclear receptor ERRγ in SH-SY5Y cells. Neuroreport. vol 26. issue 6. 2015-12-14. PMID:25807177. |
in the present study, we show for the first time that the orphan nuclear receptor estrogen-related receptor γ (errγ) is upregulated by hif-1α and plays essential roles in hif-1α-induced upregulation of dopaminergic marker molecules such as tyrosine hydroxylase and dopamine transporter. |
2015-12-14 |
2023-08-13 |
Not clear |
| Juhee Lim, Hyo-In Kim, Yeojin Bang, Wongi Seol, Hueng-Sik Choi, Hyun Jin Cho. Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter by nuclear receptor ERRγ in SH-SY5Y cells. Neuroreport. vol 26. issue 6. 2015-12-14. PMID:25807177. |
deferoxamine activated transcription and protein expression of errγ, and deferoxamine-induced upregulation of tyrosine hydroxylase and dopamine transporter was attenuated by using the errγ inverse agonist or silencing errγ. |
2015-12-14 |
2023-08-13 |
Not clear |
| Danielle Beckman, Luis E Santos, Tatiana A Americo, Jose H Ledo, Fernando G de Mello, Rafael Linde. Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice. The Journal of biological chemistry. vol 290. issue 33. 2015-12-08. PMID:26152722. |
contents of dopamine, tyrosine hydroxylase, and the 5-ht5a serotonin receptor were increased in the cerebral cortex of prp(-/-), as compared with wt mice. |
2015-12-08 |
2023-08-13 |
mouse |
| Gao Hua, Lan Xiaolei, Yang Weiwei, Wang Hao, Zhu Yuangang, Liu Dongmei, Zhang Yazhuo, Yang Hu. Protein phosphatase 2A is involved in the tyrosine hydroxylase phosphorylation regulated by α-synuclein. Neurochemical research. vol 40. issue 3. 2015-12-04. PMID:25567480. |
previous studies have shown that α-syn regulates dopamine synthesis by binding to and inhibiting tyrosine hydroxylase (th). |
2015-12-04 |
2023-08-13 |
Not clear |
| Elizabeth A Becker, Catherine A Marle. Postcontest blockade of dopamine receptors inhibits development of the winner effect in the California mouse (Peromyscus californicus). Behavioral neuroscience. vol 129. issue 2. 2015-12-04. PMID:25798633. |
dopamine (da) has been implicated because phosphorylated tyrosine hydroxylase (pth), the rate-limiting enzyme for da biosynthesis, is elevated following multiple winning experiences. |
2015-12-04 |
2023-08-13 |
mouse |