| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jordan Crago, Daniel Schlen. The effect of bifenthrin on the dopaminergic pathway in juvenile rainbow trout (Oncorhynchus mykiss). Aquatic toxicology (Amsterdam, Netherlands). vol 162. 2015-12-03. PMID:25781393. |
there was an increase in tyrosine hydroxylase transcript levels at 96 h, which is indicative of dopamine production in the brains of the 1.5 ppb (3.55 pm) bifenthrin treated rt. |
2015-12-03 |
2023-08-13 |
Not clear |
| Hongyan Gou, Di Wen, Chunling Ma, Ming Li, Yingmin Li, Wenfang Zhang, Li Liu, Bin Con. Protective effects of cholecystokinin-8 on methamphetamine-induced behavioral changes and dopaminergic neurodegeneration in mice. Behavioural brain research. vol 283. 2015-12-02. PMID:25629941. |
cck-8 pretreatment attenuated meth (10mg/kg)-induced hyperthermia, the decrease of tyrosine hydroxylase (th) and dopamine transporter (dat) in the striatum, and th in the substantia nigra. |
2015-12-02 |
2023-08-13 |
mouse |
| Csaba Ádori, Laura Glück, Swapnali Barde, Takashi Yoshitake, Gabor G Kovacs, Jan Mulder, Zsófia Maglóczky, László Havas, Kata Bölcskei, Nicholas Mitsios, Mathias Uhlén, János Szolcsányi, Jan Kehr, Annica Rönnbäck, Thue Schwartz, Jens F Rehfeld, Tibor Harkany, Miklós Palkovits, Stefan Schulz, Tomas Hökfel. Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease. Acta neuropathologica. vol 129. issue 4. 2015-11-30. PMID:25676386. |
the loss of sstr2 transcripts in the lc neurons appeared selective, since tyrosine hydroxylase, dopamine β-hydroxylase, galanin or galanin receptor 3 mrnas remained unchanged. |
2015-11-30 |
2023-08-13 |
mouse |
| Pei Jiang, Li-Hong Zhang, Hua-Lin Cai, Huan-De Li, Yi-Ping Liu, Mi-Mi Tang, Rui-Li Dang, Wen-Ye Zhu, Ying Xue, Xin H. Neurochemical effects of chronic administration of calcitriol in rats. Nutrients. vol 6. issue 12. 2015-11-25. PMID:25533012. |
additionally, calcitriol treatment promoted tyrosine hydroxylase (th) and tryptophan hydroxylase 2 (tph2) expression without changing dopamine and serotonin status. |
2015-11-25 |
2023-08-13 |
rat |
| Edyta Możdżeń, Małgorzata Kajta, Agnieszka Wąsik, Tomasz Lenda, Lucyna Antkiewicz-Michalu. Salsolinol, an endogenous compound triggers a two-phase opposing action in the central nervous system. Neurotoxicity research. vol 27. issue 3. 2015-11-25. PMID:25537852. |
ex vivo studies indicated that both acute and chronic administration of salsolinol did not affect the dopamine metabolism, its striatal concentration or α-synuclein and tyrosine hydroxylase protein level in the rat substantia nigra and striatum. |
2015-11-25 |
2023-08-13 |
mouse |
| Wei Zhang, Sungwon Kim, Robert Settlage, Wyatt McMahon, Lindsay H Sumners, Paul B Siegel, Benjamin J Dorshorst, Mark A Cline, Elizabeth R Gilber. Hypothalamic differences in expression of genes involved in monoamine synthesis and signaling pathways after insulin injection in chickens from lines selected for high and low body weight. Neurogenetics. vol 16. issue 2. 2015-11-25. PMID:25582322. |
there was greater expression of genes, mainly tyrosine hydroxylase (th), l-aromatic amino acid decarboxylase (ddc), and vesicular monoamine transporter (vmat), involved in serotonin and dopamine biosynthesis and signaling in lws than in hws vehicle-injected chickens. |
2015-11-25 |
2023-08-13 |
chicken |
| Ichiro Kawahata, Shiori Ohtaku, Yoshihisa Tomioka, Hiroshi Ichinose, Tohru Yamakun. Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system. Biochemical and biophysical research communications. vol 465. issue 1. 2015-11-23. PMID:26225746. |
dopamine or biopterin deficiency potentiates phosphorylation at (40)ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system. |
2015-11-23 |
2023-08-13 |
Not clear |
| Ichiro Kawahata, Shiori Ohtaku, Yoshihisa Tomioka, Hiroshi Ichinose, Tohru Yamakun. Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system. Biochemical and biophysical research communications. vol 465. issue 1. 2015-11-23. PMID:26225746. |
the protein amount of tyrosine hydroxylase (th), that is the rate-limiting enzyme for the biosynthesis of dopamine (da), should be tightly regulated, whereas its degradation pathway is largely unknown. |
2015-11-23 |
2023-08-13 |
Not clear |
| Inga Y Rauschenbach, Evgenia K Karpova, Natalya V Adonyeva, Olga V Andreenkova, Natalya V Faddeeva, Elena V Burdina, Alexander A Alekseev, Petr N Menshanov, Nataly E Gruntenk. Disruption of insulin signalling affects the neuroendocrine stress reaction in Drosophila females. The Journal of experimental biology. vol 217. issue Pt 20. 2015-11-20. PMID:25214494. |
we show that suppression of the insulin-like receptor (inr) in the corpus allatum, a specialised endocrine gland that synthesises jh, causes an increase in dopamine level and jh-hydrolysing activity and alters the activities of enzymes that produce as well as those that degrade dopamine [alkaline phosphatase (alp), tyrosine hydroxylase (th) and dopamine-dependent arylalkylamine n-acetyltransferase (dat)]. |
2015-11-20 |
2023-08-13 |
drosophila_melanogaster |
| Xin He, Stetson Thacker, Todd Romigh, Qi Yu, Thomas W Frazier, Charis En. Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Molecular autism. vol 6. 2015-11-20. PMID:26579216. |
cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. |
2015-11-20 |
2023-08-13 |
mouse |
| Ying Dai, Joanne Clark, Kangni Zheng, Gregory C Kujoth, Tomas A Prolla, David K Simo. Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice. Neurotoxicology and teratology. vol 46. 2015-11-16. PMID:25450660. |
in contrast, we find that susceptibility to mptp in both heterozygous and homozygous polg mutator mice at this young age is not different from that of wild type littermate controls as measured by levels of tyrosine hydroxylase positive (th+) striatal terminals, striatal dopamine and its metabolites, a marker of oxidative damage, or stereological counts of th+ and total substantia nigra neurons. |
2015-11-16 |
2023-08-13 |
mouse |
| Matej Markota, Jessica Sin, Harry Pantazopoulos, Rebecca Jonilionis, Sabina Berrett. Reduced dopamine transporter expression in the amygdala of subjects diagnosed with schizophrenia. Schizophrenia bulletin. vol 40. issue 5. 2015-11-03. PMID:24936023. |
tyrosine hydroxylase (th)-ir and dopamine beta-hydroxylase (dbh)-ir varicosities were measured to test for potential loss of varicosities and serotonin transporter (5htt)-ir for involvement of the serotoninergic system. |
2015-11-03 |
2023-08-13 |
human |
| Fumiya Takaki, Nobuaki Nakamuta, Tatsumi Kusakabe, Yoshio Yamamot. Sympathetic and sensory innervation of small intensely fluorescent (SIF) cells in rat superior cervical ganglion. Cell and tissue research. vol 359. issue 2. 2015-10-27. PMID:25416508. |
sif cells stained intensely for tyrosine hydroxylase (th), with a few cells also being immunoreactive for dopamine β-hydroxylase (dbh). |
2015-10-27 |
2023-08-13 |
rat |
| Gajanan P Shelkar, Atmaram D Kale, Uday Singh, Praful S Singru, Nishikant K Subhedar, Dadasaheb M Kokar. Alpha-melanocyte stimulating hormone modulates ethanol self-administration in posterior ventral tegmental area through melanocortin-4 receptors. Addiction biology. vol 20. issue 2. 2015-10-21. PMID:24635847. |
in the pvta, α-msh fibres were found to run close to the dopamine cells, labelled with tyrosine hydroxylase antibodies. |
2015-10-21 |
2023-08-12 |
rat |
| Xianfeng Wang, Lihua Yang, Yuanyuan Wu, Changjiang Huang, Qiangwei Wang, Jian Han, Yongyong Guo, Xiongjie Shi, Bingsheng Zho. The developmental neurotoxicity of polybrominated diphenyl ethers: Effect of DE-71 on dopamine in zebrafish larvae. Environmental toxicology and chemistry. vol 34. issue 5. 2015-10-16. PMID:25651517. |
also, de-71 resulted in a significant decrease of tyrosine hydroxylase and dopamine transporter protein levels in dopaminergic neurons. |
2015-10-16 |
2023-08-13 |
zebrafish |
| Erinna C Z Brown, Casey J Steadman, Theresa M Lee, Vasantha Padmanabhan, Michael N Lehman, Lique M Coole. Sex differences and effects of prenatal exposure to excess testosterone on ventral tegmental area dopamine neurons in adult sheep. The European journal of neuroscience. vol 41. issue 9. 2015-10-12. PMID:25784297. |
the ventral tegmental area (vta) plays a critical role in reward and motivated behaviors and is hypothesised to be targeted by prenatal t. here we report a sex difference in the number vta dopamine cells in the adult sheep, with higher numbers of tyrosine hydroxylase (th)-immunoreactive (-ir) cells in males than females. |
2015-10-12 |
2023-08-13 |
Not clear |
| Gábor Debertin, Orsolya Kántor, Tamás Kovács-Öller, Lajos Balogh, Edina Szabó-Meleg, József Orbán, Miklós Nyitrai, Béla Völgy. Tyrosine hydroxylase positive perisomatic rings are formed around various amacrine cell types in the mammalian retina. Journal of neurochemistry. vol 134. issue 3. 2015-10-09. PMID:25940543. |
dopamine (da) is released mainly in a paracrine manner by a population of tyrosine hydroxylase expressing (th(+) ) amacrine cells (ac) of the mammalian retina; thus da reaches virtually all retinal cell types by diffusion. |
2015-10-09 |
2023-08-13 |
mouse |
| Briana R De Miranda, Katriana A Popichak, Sean L Hammond, James A Miller, Stephen Safe, Ronald B Tjalken. Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease. Toxicological sciences : an official journal of the Society of Toxicology. vol 143. issue 2. 2015-10-01. PMID:25406165. |
c-dim12 prevented nuclear export of nurr1 in dopaminergic neurons and enhanced expression of the nurr1-regulated proteins tyrosine hydroxylase and the dopamine transporter. |
2015-10-01 |
2023-08-13 |
mouse |
| Shaoang Tu, Jinlong Gao, Jia Liu, Jinming Zhang, Yiyun Huang, Shasha Xu, Mei Han, Jianhui Lian. Effects of Jitai tablet, a traditional Chinese medicine, on spontaneous withdrawal symptoms and modulation of dopaminergic functions in morphine-dependent rats. Phytotherapy research : PTR. vol 29. issue 5. 2015-09-25. PMID:25626992. |
our study has shown the following: (1) pre- and post-treatment with jtt were effective at alleviating the wet dog shakes and episodes of writhing; (2) pre-treatment with jtt inhibited the morphine-induced decreases in dopamine transporter (dat), dopamine d2 receptor (d2 r) and tyrosine hydroxylase (th) levels in the striatum (p < 0.01, compared with morphine group) and maintained them at normal levels; and (3) post-treatment with jtt restored the densities of dat, d2 r and th in the striatum to normal levels (p < 0.01, compared with morphine group). |
2015-09-25 |
2023-08-13 |
rat |
| R M Khudoerkov, D N Voronkov, Yu V Dikalov. Quantitative morphochemical characterization of the neurons in substantia nigra of rat brain and its volume reconstruction. Bulletin of experimental biology and medicine. vol 156. issue 6. 2015-09-14. PMID:24824717. |
three cell compartments differing by size and proportion of neurons were identified by 3d reconstruction of the substantia nigra pars compacta of the rat brain based on immunohistochemical localization of tyrosine hydroxylase, a marker of dopamine neurons. |
2015-09-14 |
2023-08-13 |
rat |