| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Reeteka Sud, Robert N Spengler, Nader D Nader, Tracey A Ignatowsk. Antinociception occurs with a reversal in alpha 2-adrenoceptor regulation of TNF production by peripheral monocytes/macrophages from pro- to anti-inflammatory. European journal of pharmacology. vol 588. issue 2-3. 2008-09-02. PMID:18514187. |
chronic constriction injury increased tnf immunoreactivity at the lesion and the hippocampus. |
2008-09-02 |
2023-08-12 |
rat |
| Reeteka Sud, Robert N Spengler, Nader D Nader, Tracey A Ignatowsk. Antinociception occurs with a reversal in alpha 2-adrenoceptor regulation of TNF production by peripheral monocytes/macrophages from pro- to anti-inflammatory. European journal of pharmacology. vol 588. issue 2-3. 2008-09-02. PMID:18514187. |
when initiated at day-0, amitriptyline prevented increased tnf immunoreactivity in the hippocampus and at the lesion. |
2008-09-02 |
2023-08-12 |
rat |
| Yi-Rong Wang, Ren-Yi Liu, Liang-Chun Wang, Hai-Feng Mao, Jia-Qin Che. Effect of Huwentoxin-I on the Fas and TNF apoptosis pathway in the hippocampus of rat with global cerebral ischemia. Toxicon : official journal of the International Society on Toxinology. vol 50. issue 8. 2008-03-25. PMID:17900647. |
effect of huwentoxin-i on the fas and tnf apoptosis pathway in the hippocampus of rat with global cerebral ischemia. |
2008-03-25 |
2023-08-12 |
rat |
| J Szelényi, E S Viz. The catecholamine cytokine balance: interaction between the brain and the immune system. Annals of the New York Academy of Sciences. vol 1113. 2007-12-20. PMID:17584982. |
in this work, we studied the role of changes in norepinephrine (ne) level on the lipopolysaccharide (lps) evoked tumor necrosis factor (tnf)-alpha and interleukin (il)-10 response both in the plasma and in the hippocampus of mice. |
2007-12-20 |
2023-08-12 |
mouse |
| D Cumiskey, M P Butler, P N Moynagh, J J O'conno. Evidence for a role for the group I metabotropic glutamate receptor in the inhibitory effect of tumor necrosis factor-alpha on long-term potentiation. Brain research. vol 1136. issue 1. 2007-04-27. PMID:17198691. |
we have previously demonstrated in our laboratory that the inhibition of long-term potentiation (ltp) in the dentate gyrus region of the rat hippocampus, by tumor necrosis factor (tnf)-alpha, represents a biphasic response, an early phase dependent on p38 mitogen activated protein kinase (mapk) activation and a later phase, possible dependent on protein synthesis. |
2007-04-27 |
2023-08-12 |
rat |
| Izabela Figiel, Karolina Dzwone. TNFalpha and TNF receptor 1 expression in the mixed neuronal-glial cultures of hippocampal dentate gyrus exposed to glutamate or trimethyltin. Brain research. vol 1131. issue 1. 2007-03-09. PMID:17161388. |
tnfalpha and tnf receptor 1 expression in the mixed neuronal-glial cultures of hippocampal dentate gyrus exposed to glutamate or trimethyltin. |
2007-03-09 |
2023-08-12 |
rat |
| Reeteka Sud, Tracey A Ignatowski, Crystal P K Lo, Robert N Spengle. Uncovering molecular elements of brain-body communication during development and treatment of neuropathic pain. Brain, behavior, and immunity. vol 21. issue 1. 2007-02-22. PMID:16859892. |
the effects of varying levels of brain tnf on alpha(2)-adrenergic regulation of cyclic amp (camp) production in the hippocampus and sciatic nerve were investigated during the development and amitriptyline treatment of chronic pain. |
2007-02-22 |
2023-08-12 |
Not clear |
| G J Paterson, Y Ohashi, G P Reynolds, J A Pratt, B J Morri. Selective increases in the cytokine, TNFalpha, in the prefrontal cortex of PCP-treated rats and human schizophrenic subjects: influence of antipsychotic drugs. Journal of psychopharmacology (Oxford, England). vol 20. issue 5. 2006-10-19. PMID:16478754. |
the levels of the mrnas encoding tnf, il-2, il-6, tgf 1, 2, 3, il-3 and gm-csf were measured in the prefrontal cortex, cortex, hippocampus, ventral and dorsal striatum regions of male hooded long evans rats after acute drug administration. |
2006-10-19 |
2023-08-12 |
human |
| Jitbanjong Tangpong, Marsha P Cole, Rukhsana Sultana, Gururaj Joshi, Steven Estus, Mary Vore, William St Clair, Suvina Ratanachaiyavong, Daret K St Clair, D Allan Butterfiel. Adriamycin-induced, TNF-alpha-mediated central nervous system toxicity. Neurobiology of disease. vol 23. issue 1. 2006-09-06. PMID:16697651. |
the present study demonstrates that adr autofluorescence was detected only in areas of the brain located outside the blood-brain barrier, but a strong tumor necrosis factor (tnf) alpha immunoreactivity was detected in the cortex and hippocampus of adr-treated mice. |
2006-09-06 |
2023-08-12 |
mouse |
| Sachiko Tanaka, Masatoshi Ide, Toshiomi Shibutani, Hirokazu Ohtaki, Satoshi Numazawa, Seiji Shioda, Takemi Yoshid. Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats. Journal of neuroscience research. vol 83. issue 4. 2006-05-17. PMID:16429444. |
lps injected into the rat hippocampus ca1 region activated microglial cells resulting in an increased production of interleukin (il)-1beta and tumor necrosis factor (tnf)-alpha in the hippocampus during the initial stage of treatment. |
2006-05-17 |
2023-08-12 |
rat |
| Krishnan Sriram, Joanna M Matheson, Stanley A Benkovic, Diane B Miller, Michael I Luster, James P O'Callagha. Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 6. 2006-05-08. PMID:16581975. |
in the hippocampus, however, tnf receptor-deficient mice showed exacerbated neuronal damage after mptp, as evidenced by fluoro jade-b staining (to identify degenerating neurons) and decreased microtubule-associated protein-2 (map-2) immunoreactivity. |
2006-05-08 |
2023-08-12 |
mouse |
| Jessica L Reynolds, Tracey A Ignatowski, Robert N Spengle. Effect of tumor necrosis factor-alpha on the reciprocal G-protein-induced regulation of norepinephrine release by the alpha2-adrenergic receptor. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15672410. |
tnf and alpha2-adrenergic regulation of ne release was investigated in rat hippocampal slices incubated with pertussis toxin (ptx). |
2005-07-15 |
2023-08-12 |
rat |
| Jessica L Reynolds, Tracey A Ignatowski, Robert N Spengle. Effect of tumor necrosis factor-alpha on the reciprocal G-protein-induced regulation of norepinephrine release by the alpha2-adrenergic receptor. Journal of neuroscience research. vol 79. issue 6. 2005-07-15. PMID:15672410. |
ptx exposure of hippocampal slices prevents agonist-induced increases in galpha(i/o) labeling with a gtp analog; after subsequent tnf exposure, agonist-induced increases in galpha(i/o) labeling are restored. |
2005-07-15 |
2023-08-12 |
rat |
| Brian M Berg, Jonathan P Godbout, Jing Chen, Keith W Kelley, Rodney W Johnso. alpha-Tocopherol and selenium facilitate recovery from lipopolysaccharide-induced sickness in aged mice. The Journal of nutrition. vol 135. issue 5. 2005-07-06. PMID:15867297. |
regardless of diet, interleukin (il)-6, il-1beta, and tumor necrosis factor (tnf)alpha mrna levels were elevated by lps approximately 3-fold in cortex, cerebellum, striatum, and hippocampus. |
2005-07-06 |
2023-08-12 |
mouse |
| Tracey A Ignatowski, Reeteka Sud, Jessica L Reynolds, Paul R Knight, Robert N Spengle. The dissipation of neuropathic pain paradoxically involves the presence of tumor necrosis factor-alpha (TNF). Neuropharmacology. vol 48. issue 3. 2005-05-24. PMID:15721177. |
tnf-inhibition of ne release transforms to facilitation in the hippocampus of rats administered antidepressants (treat neuropathic pain), contemporaneous with decreased neuron tnf. |
2005-05-24 |
2023-08-12 |
rat |
| Zhihong Guo, Titilola Iyun, Weiming Fu, Peisu Zhang, Mark P Mattso. Bone marrow transplantation reveals roles for brain macrophage/microglia TNF signaling and nitric oxide production in excitotoxic neuronal death. Neuromolecular medicine. vol 5. issue 3. 2005-05-03. PMID:15626822. |
mice in which endogenous bmm were replaced with cells from mice lacking p55 and p75 tumor necrosis factor (tnf) receptors exhibit increased vulnerability of hippocampal neurons to excitotoxic injury suggesting a role for tnf signaling in bmm in the excitotoxic injury response. |
2005-05-03 |
2023-08-12 |
mouse |
| Jessica L Reynolds, Tracey A Ignatowski, Samuel Gallant, Robert N Spengle. Amitriptyline administration transforms tumor necrosis factor-alpha regulation of norepinephrine release in the brain. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364025. |
administration of the antidepressant drug amitriptyline for 1 day or 14 days to rats significantly increases tnf bioactivity in total homogenates of the locus coeruleus (lc) and the hippocampus as assessed by the wehi-13var bioassay. |
2004-12-21 |
2023-08-12 |
rat |
| Jessica L Reynolds, Tracey A Ignatowski, Samuel Gallant, Robert N Spengle. Amitriptyline administration transforms tumor necrosis factor-alpha regulation of norepinephrine release in the brain. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364025. |
superfusion of hippocampal slices isolated from rats chronically (14 days) administered amitriptyline demonstrates that tnf inhibition of ne release is transformed, such that tnf facilitates ne release, dependent upon alpha(2)-adrenergic activation. |
2004-12-21 |
2023-08-12 |
rat |
| Jessica L Reynolds, Tracey A Ignatowski, Reeteka Sud, Robert N Spengle. Brain-derived tumor necrosis factor-alpha and its involvement in noradrenergic neuron functioning involved in the mechanism of action of an antidepressant. The Journal of pharmacology and experimental therapeutics. vol 310. issue 3. 2004-11-01. PMID:15082752. |
to establish this role, field stimulation and superfusion of rat hippocampal slices was employed to investigate the regulation of norepinephrine (ne) release by tnf. |
2004-11-01 |
2023-08-12 |
rat |
| Jessica L Reynolds, Tracey A Ignatowski, Reeteka Sud, Robert N Spengle. Brain-derived tumor necrosis factor-alpha and its involvement in noradrenergic neuron functioning involved in the mechanism of action of an antidepressant. The Journal of pharmacology and experimental therapeutics. vol 310. issue 3. 2004-11-01. PMID:15082752. |
tnf regulation of ne release in hippocampal slices isolated from these rats was compared with slices isolated from rats chronically administered desipramine alone. |
2004-11-01 |
2023-08-12 |
rat |