| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Keith Del Villar, Carol A Mille. Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 12. 2004-05-10. PMID:15007167. |
down-regulation of denn/madd, a tnf receptor binding protein, correlates with neuronal cell death in alzheimer's disease brain and hippocampal neurons. |
2004-05-10 |
2023-08-12 |
mouse |
| Nina Drøjdahl, Christina Fenger, Helle H Nielsen, Trevor Owens, Bente Finse. Dynamics of oligodendrocyte responses to anterograde axonal (Wallerian) and terminal degeneration in normal and TNF-transgenic mice. Journal of neuroscience research. vol 75. issue 2. 2004-03-12. PMID:14705141. |
transectioning of the entorhino-dentate perforant path axonal projection increased hippocampal tnf mrna expression in both types of mice, but to significantly larger levels in the tnf-transgenics. |
2004-03-12 |
2023-08-12 |
mouse |
| Alessandro Bartolomucci, Paola Palanza, Stefano Parmigiani, Tiziana Pederzani, Elodie Merlot, Pierre J Neveu, Robert Dantze. Chronic psychosocial stress down-regulates central cytokines mRNA. Brain research bulletin. vol 62. issue 3. 2004-02-26. PMID:14698350. |
mice subjected to chronic psychosocial stress showed decreased interleukin (il)-1beta mrna levels in the hippocampus, decreased il-1receptor antagonist in the striatum and pituitary, decreased tumor necrosis factor (tnf)-alpha in the striatum and hippocampus, and decreased glucocorticoid receptor (gr) in the striatum and hippocampus compared to group housed sibling mice. |
2004-02-26 |
2023-08-12 |
mouse |
| Weihong Pan, Abba J Kastin, Tova Rigai, Robert McLay, Chaim G Pic. Increased hippocampal uptake of tumor necrosis factor alpha and behavioral changes in mice. Experimental brain research. vol 149. issue 2. 2003-06-02. PMID:12610687. |
this increase, measured by use of radiolabeled murine tnf alpha, occurred only in the right hippocampus 24 h after injury and returned to normal at 1 week. |
2003-06-02 |
2023-08-12 |
mouse |
| Weihong Pan, Abba J Kastin, Tova Rigai, Robert McLay, Chaim G Pic. Increased hippocampal uptake of tumor necrosis factor alpha and behavioral changes in mice. Experimental brain research. vol 149. issue 2. 2003-06-02. PMID:12610687. |
therefore, the selective entry of tnf alpha in the injured right hippocampus may be explained by enhanced transport across the bbb. |
2003-06-02 |
2023-08-12 |
mouse |
| Weihong Pan, Abba J Kastin, Tova Rigai, Robert McLay, Chaim G Pic. Increased hippocampal uptake of tumor necrosis factor alpha and behavioral changes in mice. Experimental brain research. vol 149. issue 2. 2003-06-02. PMID:12610687. |
we conclude that mild, blunt brain trauma involving the hippocampus causes specific upregulation of tnf alpha transport and a selective change in exploratory behavior. |
2003-06-02 |
2023-08-12 |
mouse |
| A E Renauld, R N Spengle. Tumor necrosis factor expressed by primary hippocampal neurons and SH-SY5Y cells is regulated by alpha(2)-adrenergic receptor activation. Journal of neuroscience research. vol 67. issue 2. 2002-02-21. PMID:11782970. |
potassium-induced depolarization resulted in the release of tnf in hippocampal neuron cultures within 15 min but not until 24 hr in sh-sy5y cultures demonstrating a temporally mediated event dependent upon cell type. |
2002-02-21 |
2023-08-12 |
rat |
| G D Jahnke, S Brunssen, W E Maier, G J Harr. Neurotoxicant-induced elevation of adrenomedullin expression in hippocampus and glia cultures. Journal of neuroscience research. vol 66. issue 3. 2002-01-25. PMID:11746364. |
mrna levels for tumor necrosis factor (tnf)-alpha, interleukin (il)-1alpha, gfap, and am in the hippocampus were increased over control levels within 4 days following tmt. |
2002-01-25 |
2023-08-12 |
Not clear |
| K L Lambertsen, R Gregersen, N Drøjdahl, T Owens, B Finse. A specific and sensitive method for visualization of tumor necrosis factor in the murine central nervous system. Brain research. Brain research protocols. vol 7. issue 2. 2001-07-26. PMID:11356385. |
we present here sensitive, simple and robust methods for detection of tumor necrosis factor (tnf) mrna and tnf in histological sections and homogenates of brain tissue from mice subjected to focal cerebral ischemia or hippocampal axonal lesioning. |
2001-07-26 |
2023-08-12 |
mouse |
| E M Eves, C Skoczylas, K Yoshida, E S Alnemri, M R Rosne. FGF induces a switch in death receptor pathways in neuronal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 14. 2001-07-26. PMID:11438575. |
using a conditionally immortalized rat hippocampal cell line, h19-7, and primary hippocampal cultures, we now demonstrate that fgf2 treatment differentially regulates members of the tumor necrosis factor (tnf) superfamily of death domain receptors and their ligands. |
2001-07-26 |
2023-08-12 |
rat |
| W Wang, C Lönnroth, E Svanberg, K Lundhol. Cytokine and cyclooxygenase-2 protein in brain areas of tumor-bearing mice with prostanoid-related anorexia. Cancer research. vol 61. issue 12. 2001-07-12. PMID:11406541. |
we have therefore evaluated, by immunohistochemical image analyses, time course changes of interleukin (il)-1beta, il-6, tumor necrosis factor (tnf) alpha, il-6 receptor (gp130), il-1 receptor i, and cyclooxygenase (cox)-2 protein in brain cortex, hippocampus and the ventromedial hypothalamic nucleus (vmh) in tumor-bearing mice with prostanoid-related anorexia. |
2001-07-12 |
2023-08-12 |
mouse |
| T J Nickola, T A Ignatowski, J L Reynolds, R N Spengle. Antidepressant drug-induced alterations in neuron-localized tumor necrosis factor-alpha mRNA and alpha(2)-adrenergic receptor sensitivity. The Journal of pharmacology and experimental therapeutics. vol 297. issue 2. 2001-05-21. PMID:11303058. |
superfusion of hippocampal slices obtained from rats chronically administered the antidepressant drug zimelidine demonstrates that tnf-mediated inhibition of [(3)h]ne release is transformed, such that [(3)h]ne release is potentiated in the presence of tnf, an effect that occurs in association with alpha(2)-adrenergic receptor activation. |
2001-05-21 |
2023-08-12 |
rat |
| T J Nickola, T A Ignatowski, R N Spengle. Antidepressant drug administration modifies the interactive relationship between alpha(2)-adrenergic sensitivity and levels of TNF in the rat brain. Journal of neuroimmunology. vol 107. issue 1. 2000-06-21. PMID:10808050. |
additionally, the role of tnf as a neuromodulator is demonstrated by in vivo microinfusion of rrtnf proximal to the hippocampus. |
2000-06-21 |
2023-08-12 |
rat |
| T J Nickola, T A Ignatowski, R N Spengle. Antidepressant drug administration modifies the interactive relationship between alpha(2)-adrenergic sensitivity and levels of TNF in the rat brain. Journal of neuroimmunology. vol 107. issue 1. 2000-06-21. PMID:10808050. |
administration to rats of an alpha(2)-adrenergic receptor agonist (clonidine) decreases levels of tnf in homogenates of rat locus coeruleus and hippocampus within 7.5 min. |
2000-06-21 |
2023-08-12 |
rat |
| T J Nickola, T A Ignatowski, R N Spengle. Antidepressant drug administration modifies the interactive relationship between alpha(2)-adrenergic sensitivity and levels of TNF in the rat brain. Journal of neuroimmunology. vol 107. issue 1. 2000-06-21. PMID:10808050. |
this transformation to an increase in total levels of tnf also occurs, although transiently, in the hippocampus following acute (1 day) antidepressant drug administration. |
2000-06-21 |
2023-08-12 |
rat |
| B C Albensi, M P Mattso. Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity. Synapse (New York, N.Y.). vol 35. issue 2. 2000-02-17. PMID:10611641. |
evidence for the involvement of tnf and nf-kappab in hippocampal synaptic plasticity. |
2000-02-17 |
2023-08-12 |
mouse |
| B C Albensi, M P Mattso. Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity. Synapse (New York, N.Y.). vol 35. issue 2. 2000-02-17. PMID:10611641. |
because data indicate that tnf is produced, and nf-kappab activated, under conditions associated with learning and memory, we performed experiments in the hippocampal slice preparation aimed at elucidating roles for tnf and nf-kappab in modulating synaptic plasticity. |
2000-02-17 |
2023-08-12 |
mouse |
| B C Albensi, M P Mattso. Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity. Synapse (New York, N.Y.). vol 35. issue 2. 2000-02-17. PMID:10611641. |
collectively, these data suggest important roles for tnf and signaling pathways that modulate nf-kappab activity in regulation of hippocampal synaptic plasticity. |
2000-02-17 |
2023-08-12 |
mouse |
| T A Ignatowski, W C Covey, P R Knight, C M Severin, T J Nickola, R N Spengle. Brain-derived TNFalpha mediates neuropathic pain. Brain research. vol 841. issue 1-2. 1999-11-17. PMID:10546989. |
bioactive tnf levels are elevated in the hippocampus. |
1999-11-17 |
2023-08-12 |
rat |
| T A Ignatowski, W C Covey, P R Knight, C M Severin, T J Nickola, R N Spengle. Brain-derived TNFalpha mediates neuropathic pain. Brain research. vol 841. issue 1-2. 1999-11-17. PMID:10546989. |
during the period of injury, hippocampal noradrenergic neurotransmission demonstrates a decrease in stimulated norepinephrine (ne) release, concomitant with elevated hippocampal tnf levels. |
1999-11-17 |
2023-08-12 |
rat |