Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S Layé, P Parnet, E Goujon, R Dantze. Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Brain research. Molecular brain research. vol 27. issue 1. 1995-04-06. PMID:7877446. |
the reverse transcription polymerase chain reaction (rt-pcr) was used to assess the induction of mrna of the proinflammatory cytokines il-1 beta, il-6 and tnf alpha in the spleen, pituitary, hypothalamus and hippocampus of mice after an intraperitoneal injection of lipopolysaccharide (lps, 10 micrograms/mouse). |
1995-04-06 |
2023-08-12 |
mouse |
J L Tchelingerian, L Vignais, C Jacqu. TNF alpha gene expression is induced in neurones after a hippocampal lesion. Neuroreport. vol 5. issue 5. 1994-08-08. PMID:8025249. |
however, an immunoreactivity for tnf alpha has been observed recently in adult mouse brain after a lesion to the hippocampus. |
1994-08-08 |
2023-08-12 |
mouse |
J L Tchelingerian, L Vignais, C Jacqu. TNF alpha gene expression is induced in neurones after a hippocampal lesion. Neuroreport. vol 5. issue 5. 1994-08-08. PMID:8025249. |
tnf alpha gene expression is induced in neurones after a hippocampal lesion. |
1994-08-08 |
2023-08-12 |
mouse |
B Cheng, S Christakos, M P Mattso. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron. vol 12. issue 1. 1994-03-01. PMID:7507336. |
we now report that tnf beta and tnf alpha (1-100 ng/ml) can protect cultured embryonic rat hippocampal, septal, and cortical neurons against glucose deprivation-induced injury and excitatory amino acid toxicity. |
1994-03-01 |
2023-08-12 |
rat |
J L Tchelingerian, J Quinonero, J Booss, C Jacqu. Localization of TNF alpha and IL-1 alpha immunoreactivities in striatal neurons after surgical injury to the hippocampus. Neuron. vol 10. issue 2. 1993-03-26. PMID:8439410. |
localization of tnf alpha and il-1 alpha immunoreactivities in striatal neurons after surgical injury to the hippocampus. |
1993-03-26 |
2023-08-12 |
mouse |
M Minami, Y Kuraishi, M Sato. Effects of kainic acid on messenger RNA levels of IL-1 beta, IL-6, TNF alpha and LIF in the rat brain. Biochemical and biophysical research communications. vol 176. issue 2. 1991-06-06. PMID:1709015. |
il-6 mrna was weakly induced in the hippocampus (hpp) 2 h after the injection of kainic acid and was markedly increased in the cc, hpp, thl, and ht at 4 h. the level of tnf alpha mrna was highly elevated in the cc, hpp, striatum (str), thl and ht at 2 and 4 h after the injection. |
1991-06-06 |
2023-08-11 |
rat |