| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Luethy, Amy L Johnson, Darko Stefanovski, Raymond C Boston, James Anthony Orsin. Glucose and insulin response after intravenous and subcutaneous somatostatin administration in healthy horses. Journal of veterinary pharmacology and therapeutics. vol 42. issue 5. 2020-01-06. PMID:31325161. |
both iv and sq somatostatin resulted in decreased insulin and increased glucose concentrations. |
2020-01-06 |
2023-08-13 |
Not clear |
| Daniela Luethy, Amy L Johnson, Darko Stefanovski, Raymond C Boston, James Anthony Orsin. Glucose and insulin response after intravenous and subcutaneous somatostatin administration in healthy horses. Journal of veterinary pharmacology and therapeutics. vol 42. issue 5. 2020-01-06. PMID:31325161. |
sq somatostatin resulted in a longer clinical effect, with return to baseline insulin occurring at 1.5 hr postadministration, versus 45 min for iv. |
2020-01-06 |
2023-08-13 |
Not clear |
| Daniela Luethy, Amy L Johnson, Darko Stefanovski, Raymond C Boston, James Anthony Orsin. Glucose and insulin response after intravenous and subcutaneous somatostatin administration in healthy horses. Journal of veterinary pharmacology and therapeutics. vol 42. issue 5. 2020-01-06. PMID:31325161. |
both iv and sq administration of somatostatin to normal horses resulted in decreased insulin and increased glucose concentrations, likely due to suppression of insulin secretion by somatostatin. |
2020-01-06 |
2023-08-13 |
Not clear |
| Daniela Luethy, Amy L Johnson, Darko Stefanovski, Raymond C Boston, James Anthony Orsin. Glucose and insulin response after intravenous and subcutaneous somatostatin administration in healthy horses. Journal of veterinary pharmacology and therapeutics. vol 42. issue 5. 2020-01-06. PMID:31325161. |
this study provides additional information regarding the effect of somatostatin administration on insulin and glucose concentrations in clinically healthy horses. |
2020-01-06 |
2023-08-13 |
Not clear |
| Vladimir M Subboti. A hypothesis on paradoxical privileged portal vein metastasis of hepatocellular carcinoma. Can organ evolution shed light on patterns of human pathology, and vice versa? Medical hypotheses. vol 126. 2019-12-06. PMID:31010487. |
the analysis suggests that the appearance of the portal venous system, supplying hormones and growth factors of pancreatic family, which includes insulin, glucagon, somatostatin, and pancreatic polypeptide (hgfpf) to midgut diverticulum in the early evolution of chordates (in an amphioxus-like ancestral animal), promoted differentiation of enterocytes into hepatocytes and their further evolution to the liver of vertebrates. |
2019-12-06 |
2023-08-13 |
human |
| Pontirol. Peptide hormones: Review of current and emerging uses by nasal delivery. Advanced drug delivery reviews. vol 29. issue 1-2. 2019-11-20. PMID:10837581. |
luteinizing hormone releasing hormone, the analogues, desmopressin, oxytocin and salmon calcitonin are already marketed for intranasal administration; for salmon calcitonin, studies about bioavailability have been scanty in the past, but should be re-considered in order to fully explore its clinical benefit.intranasal peptide hormones not yet on the market are insulin, glucagon, growth hormone releasing hormone (ghrh) and ghrp, gh and somatostatin, but the scenario is likely to change in a short period of time. |
2019-11-20 |
2023-08-12 |
Not clear |
| Boguslawa Baranowska, Malgorzata Radzikowska, Elzbieta Wasilewska-Dziubinska, Artur Plonowski, Krzysztof Roguski, Anna Legowska, Józef Przybylsk. New analogs of somatostatin: inhibiting effectively GH, glucagon and insulin levels. Neuro endocrinology letters. vol 20. issue 3-4. 2019-11-20. PMID:11462119. |
new analogs of somatostatin: inhibiting effectively gh, glucagon and insulin levels. |
2019-11-20 |
2023-08-12 |
rat |
| Elisabeth Vanhems, Martine Delbos, Josiane Girardi. Insulin and Neuroparsin Promote Neurite Outgrowth in Cultured Locust CNS. The European journal of neuroscience. vol 2. issue 9. 2019-11-20. PMID:12106278. |
explants from the third thoracic ganglion (embryonic day 9) were grown in a serum-free medium and exposed to insulin, neuroparsin, a recently characterized insect neurohormone, somatostatin and two insect hormones: 20-hydroxyecdysone and juvenile hormone. |
2019-11-20 |
2023-08-12 |
Not clear |
| Mika Sakaki, Mitsuyoshi Hirokawa, Toshiaki Sano, Hidehisa Horiguchi, Shingo Wakatsuki, Shinya Ogat. Gallbladder Adenocarcinoma with Florid Neuroendocrine Cell Nests and Extensive Paneth Cell Metaplasia. Endocrine pathology. vol 11. issue 4. 2019-11-20. PMID:12114761. |
they were immunopositive for serotonin but negative for insulin, glucagon, somatostatin, and pancreatic polypeptide (pp). |
2019-11-20 |
2023-08-12 |
Not clear |
| Iacopo Gesmundo, Tania Villanova, Dana Banfi, Giacomo Gamba, Riccarda Granat. Role of Melatonin, Galanin, and RFamide Neuropeptides QRFP26 and QRFP43 in the Neuroendocrine Control of Pancreatic β-Cell Function. Frontiers in endocrinology. vol 8. 2019-11-20. PMID:28729853. |
the endocrine function of the pancreas is controlled by islets within the exocrine pancreatic tissue that release hormones like insulin, glucagon, somatostatin, pancreatic polypeptide, and ghrelin. |
2019-11-20 |
2023-08-13 |
Not clear |
| G Türk, A Rişvanlı, A O Çeribaşı, M Sönmez, A Yüce, M Güvenç, H Arslan Özkan, N Canlı, M Yama. Effect of gestational diabetes mellitus on testis and pancreatic tissues of male offspring. Andrologia. 2019-11-20. PMID:29411891. |
although some histopathological damages were observed in testes of both stz-40 and stz-60 groups, there were no detectable differences between the groups in density of insulin, glucagon and somatostatin receptors in pancreas. |
2019-11-20 |
2023-08-13 |
rat |
| C R Marchand, C Colar. Presence of cells and fibers immunoreactive toward antibodies to different peptides or amine in the digestive tract of the snailHelix aspersa. Journal of morphology. vol 207. issue 2. 2019-11-20. PMID:29865499. |
an immunocytological study of four different parts of the gut of helix aspersa clearly demonstrates the presence of many cells and fibers immunoreactive toward antibodies directed to vertebrate (α, β-endorphin, α, β-msh, acth 1-24 and acth 17-39, met-enkephalin, somatostatin, insulin, glucagon, p.p., serotonin) or invertebrate (fmrf-amide) peptides. |
2019-11-20 |
2023-08-13 |
Not clear |
| Julien Calvani, Pauline Lopez, Sabine Sarnacki, Thierry Jo Molina, Laure Gibault, Monique Fabre, Raphael Scharfmann, Carmen Capito, Louise Galmich. Solid pseudopapillary neoplasms of the pancreas do not express major pancreatic markers in pediatric patients. Human pathology. vol 83. 2019-11-15. PMID:30130629. |
in all cases, tumor cells were negative for the following markers: pdx1, sox9, ptf1a, nkx2.2, chromogranin a, glucagon, insulin, somatostatin, ghrelin, pancreatic polypeptide, amylase, gfap, calretinin, epcam, and estrogen receptor α. |
2019-11-15 |
2023-08-13 |
human |
| Timothy P Sheets, Ki-Eun Park, Chi-Hun Park, Steven M Swift, Anne Powell, David M Donovan, Bhanu P Telug. Targeted Mutation of NGN3 Gene Disrupts Pancreatic Endocrine Cell Development in Pigs. Scientific reports. vol 8. issue 1. 2019-10-21. PMID:29483633. |
one of the piglets was identified as an in-frame biallelic knockout (Δ2/Δ2), which showed a loss of putative ngn3-downstream target genes: neurod1 and pax4, as well as insulin, glucagon, somatostatin and pancreatic polypeptide-y. |
2019-10-21 |
2023-08-13 |
Not clear |
| Timothy P Sheets, Ki-Eun Park, Chi-Hun Park, Steven M Swift, Anne Powell, David M Donovan, Bhanu P Telug. Targeted Mutation of NGN3 Gene Disrupts Pancreatic Endocrine Cell Development in Pigs. Scientific reports. vol 8. issue 1. 2019-10-21. PMID:29483633. |
expression of pancreatic endocrine hormones: insulin, glucagon, and somatostatin were lost. |
2019-10-21 |
2023-08-13 |
Not clear |
| F Rafael Castiello, Maryam Tabrizia. Gold nanoparticle amplification strategies for multiplex SPRi-based immunosensing of human pancreatic islet hormones. The Analyst. vol 144. issue 8. 2019-08-08. PMID:30864587. |
in the islets, somatostatin works as a paracrine inhibitor of insulin and glucagon secretion. |
2019-08-08 |
2023-08-13 |
human |
| F Rafael Castiello, Maryam Tabrizia. Gold nanoparticle amplification strategies for multiplex SPRi-based immunosensing of human pancreatic islet hormones. The Analyst. vol 144. issue 8. 2019-08-08. PMID:30864587. |
thus, the simultaneous detection of insulin, glucagon and somatostatin could help understand such communications. |
2019-08-08 |
2023-08-13 |
human |
| F Rafael Castiello, Maryam Tabrizia. Gold nanoparticle amplification strategies for multiplex SPRi-based immunosensing of human pancreatic islet hormones. The Analyst. vol 144. issue 8. 2019-08-08. PMID:30864587. |
previously, the authors introduced an spri biosensor to simultaneously monitor insulin, glucagon and somatostatin using an indirect competitive immunoassay. |
2019-08-08 |
2023-08-13 |
human |
| F Rafael Castiello, Maryam Tabrizia. Gold nanoparticle amplification strategies for multiplex SPRi-based immunosensing of human pancreatic islet hormones. The Analyst. vol 144. issue 8. 2019-08-08. PMID:30864587. |
among these strategies an immunoassay using gnp-ab2 conjugates was able to achieve multiplex detection of the three hormones without cross-reactivity and with 9-fold lod improvement for insulin, 10-fold for glucagon and 200-fold for somatostatin when compared to the spri biosensor without gnps. |
2019-08-08 |
2023-08-13 |
human |
| Patrik Rorsman, Mark O Huisin. The somatostatin-secreting pancreatic δ-cell in health and disease. Nature reviews. Endocrinology. vol 14. issue 7. 2019-07-16. PMID:29773871. |
factors released by neighbouring α-cells or β-cells amplify the glucose-induced effects on somatostatin secretion from δ-cells, which act locally within the islets as paracrine or autocrine inhibitors of insulin, glucagon and somatostatin secretion. |
2019-07-16 |
2023-08-13 |
Not clear |