| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Prashanth Vallabhajosyula, Laxminarayana Korutla, Andreas Habertheuer, Ming Yu, Susan Rostami, Chao-Xing Yuan, Sanjana Reddy, Chengyang Liu, Varun Korutla, Brigitte Koeberlein, Jennifer Trofe-Clark, Michael R Rickels, Ali Naj. Tissue-specific exosome biomarkers for noninvasively monitoring immunologic rejection of transplanted tissue. The Journal of clinical investigation. vol 127. issue 4. 2017-09-12. PMID:28319051. |
transplant islet exosomes were purified using anti-hla antibody-conjugated beads, and their cargoes contained the islet endocrine hormone markers insulin, glucagon, and somatostatin. |
2017-09-12 |
2023-08-13 |
human |
| D A Bereiter, F Rohner-Jeanrenaud, H -R Berthoud, B Jeanrenau. CNS modulation of pancreatic endocrine function : Multiple modes of expression. Diabetologia. vol 20. issue Suppl 1. 2017-08-23. PMID:27942830. |
chronic lesions of the ventromedial hypothalamus increased secretion of insulin and glucagon, and decreased secretion of somatostatin when the pancreas was subsequently isolated and perfused. |
2017-08-23 |
2023-08-13 |
mouse |
| Jakob Dal, Katrine Lundby Høyer, Steen Bønløkke Pedersen, Nils Erik Magnusson, Peter Bjerring, Jan Frystyk, Niels Møller, Niels Jessen, Jens Otto Lunde Jørgense. Growth Hormone and Insulin Signaling in Acromegaly: Impact of Surgery Versus Somatostatin Analog Treatment. The Journal of clinical endocrinology and metabolism. vol 101. issue 10. 2017-06-30. PMID:27466699. |
growth hormone and insulin signaling in acromegaly: impact of surgery versus somatostatin analog treatment. |
2017-06-30 |
2023-08-13 |
Not clear |
| Jakob Dal, Katrine Lundby Høyer, Steen Bønløkke Pedersen, Nils Erik Magnusson, Peter Bjerring, Jan Frystyk, Niels Møller, Niels Jessen, Jens Otto Lunde Jørgense. Growth Hormone and Insulin Signaling in Acromegaly: Impact of Surgery Versus Somatostatin Analog Treatment. The Journal of clinical endocrinology and metabolism. vol 101. issue 10. 2017-06-30. PMID:27466699. |
somatostatin analogs (sas) used in acromegaly to suppress gh secretion and tumor growth also suppress insulin secretion and may impact gh signaling. |
2017-06-30 |
2023-08-13 |
Not clear |
| Hongyan Shuai, Yunjian Xu, Qian Yu, Erik Gylfe, Anders Tenghol. Fluorescent protein vectors for pancreatic islet cell identification in live-cell imaging. Pflugers Archiv : European journal of physiology. vol 468. issue 10. 2017-06-30. PMID:27539300. |
we constructed six adenoviral vectors for expression of red and green fluorescent proteins controlled by the insulin, preproglucagon, somatostatin, or pancreatic polypeptide promoters. |
2017-06-30 |
2023-08-13 |
mouse |
| Erik T Jansson, Troy J Comi, Stanislav S Rubakhin, Jonathan V Sweedle. Single Cell Peptide Heterogeneity of Rat Islets of Langerhans. ACS chemical biology. vol 11. issue 9. 2017-06-26. PMID:27414158. |
within a single islet, cellular heterogeneity was evident from the exclusive expression of the canonical biomarkers glucagon, insulin, pancreatic polypeptide (pp), and somatostatin within α-, β-, γ-, and δ-cells, respectively. |
2017-06-26 |
2023-08-13 |
human |
| Sayali A Pendharkar, Varsha M Asrani, Amy Y Xiao, Harry D Yoon, Rinki Murphy, John A Windsor, Maxim S Petro. Relationship between pancreatic hormones and glucose metabolism: A cross-sectional study in patients after acute pancreatitis. American journal of physiology. Gastrointestinal and liver physiology. vol 311. issue 1. 2017-06-21. PMID:27173509. |
fasting venous blood was collected from all patients and used for analysis of insulin, glucagon, pancreatic polypeptide, amylin, somatostatin, c-peptide, glucose, and hemoglobin a1c. |
2017-06-21 |
2023-08-13 |
Not clear |
| Tore Hedbäck, Peter Almgren, Peter M Nilsson, Olle Melande. N-Terminal Prosomatostatin as a Risk Marker for Cardiovascular Disease and Diabetes in a General Population. The Journal of clinical endocrinology and metabolism. vol 101. issue 9. 2017-06-20. PMID:27399347. |
somatostatin inhibits a range of hormones, including gh, insulin, and glucagon, but little is known about its role in the development of cardiometabolic disease. |
2017-06-20 |
2023-08-13 |
Not clear |
| Christopher A Reissaus, David W Pisto. Reestablishment of Glucose Inhibition of Glucagon Secretion in Small Pseudoislets. Diabetes. vol 66. issue 4. 2017-06-13. PMID:28130310. |
the recovery of regulated glucagon secretion from α-cells in small pseudoislets depends upon the combined action of paracrine factors, such as insulin and somatostatin, and juxtacrine signals between epha4/7 on α-cells and ephrins on β-cells. |
2017-06-13 |
2023-08-13 |
human |
| Ying Zhao, Qinghua Fang, Susanne G Straub, Manfred Lindau, Geoffrey W G Shar. Prostaglandin E1 inhibits endocytosis in the β-cell endocytosis. The Journal of endocrinology. vol 229. issue 3. 2017-06-08. PMID:27068696. |
prostaglandins inhibit insulin secretion in a manner similar to that of norepinephrine (ne) and somatostatin. |
2017-06-08 |
2023-08-13 |
Not clear |
| Pradeep R Dumpala, Robert W Holdcraft, Prithy C Martis, Melissa A Laramore, Thomas S Parker, Daniel M Levine, Barry H Smith, Lawrence S Gazd. Retention of gene expression in porcine islets after agarose encapsulation and long-term culture. Biochemical and biophysical research communications. vol 476. issue 4. 2017-05-22. PMID:27261433. |
importantly, the expression levels of genes that code for critical hormones secreted by islets (insulin, glucagon, and somatostatin) as well as transcripts encoding proteins involved in their packaging and secretion are unchanged. |
2017-05-22 |
2023-08-13 |
Not clear |
| I L Iessi, Y K Sinzato, F Q Gallego, J H Nielsen, D C Damascen. Effect of Diabetes on Circulating Pancreatic Hormones in Pregnant Rats and Their Offspring. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 48. issue 10. 2017-03-14. PMID:27632150. |
the aim of the study was to investigate the role of diabetic intrauterine environment on circulating insulin, glucagon, and somatostatin levels in pregnant rats, fetuses, and offspring. |
2017-03-14 |
2023-08-13 |
rat |
| I L Iessi, Y K Sinzato, F Q Gallego, J H Nielsen, D C Damascen. Effect of Diabetes on Circulating Pancreatic Hormones in Pregnant Rats and Their Offspring. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 48. issue 10. 2017-03-14. PMID:27632150. |
sd newborns had diminished total pancreatic insulin and plasma somatostatin compared to the other groups. |
2017-03-14 |
2023-08-13 |
rat |
| Olli Helminen, Heikki Huhta, Joonas H Kauppila, Petri P Lehenkari, Juha Saarnio, Tuomo J Karttune. Localization of nucleic acid-sensing toll-like receptors in human and mouse pancreas. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 125. issue 2. 2017-02-07. PMID:28028829. |
immunohistochemical double-stainings for the tlrs and insulin, glucagon or somatostatin, respectively, were performed along with appropriate controls. |
2017-02-07 |
2023-08-13 |
mouse |
| Andrew Schmudlach, Jeremy Felton, Cynthia Cipolla, Liangliang Sun, Robert T Kennedy, Norman J Dovich. Sample preparation protocol for bottom-up proteomic analysis of the secretome of the islets of Langerhans. The Analyst. vol 141. issue 5. 2017-01-04. PMID:26863548. |
as expected, the identified proteins included insulin 1 and 2, somatostatin, and glucagon, the four main secreted components from islets. |
2017-01-04 |
2023-08-13 |
Not clear |
| Jong Hyun Kim, Hyung Woo Kim, Kyoung Je Cha, Jiyou Han, Yu Jin Jang, Dong Sung Kim, Jong-Hoon Ki. Nanotopography Promotes Pancreatic Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells. ACS nano. vol 10. issue 3. 2016-12-16. PMID:26900863. |
furthermore, in the presence of biochemical factors, 200 nm nanopore-patterned surfaces profoundly enhanced the derivation of pancreatic endocrine cells producing insulin, glucagon, or somatostatin. |
2016-12-16 |
2023-08-13 |
human |
| Deborah A Striegel, Manami Hara, Vipul Periwa. Adaptation of pancreatic islet cyto-architecture during development. Physical biology. vol 13. issue 2. 2016-12-14. PMID:27063927. |
islets consist of endocrine cells, primarily α, β, and δ cells, which secrete glucagon, insulin, and somatostatin, respectively. |
2016-12-14 |
2023-08-13 |
human |
| Claire L Meek, Hannah B Lewis, Frank Reimann, Fiona M Gribble, Adrian J Par. The effect of bariatric surgery on gastrointestinal and pancreatic peptide hormones. Peptides. vol 77. 2016-12-13. PMID:26344355. |
the aim of this review is to summarise the effects of different bariatric surgery procedures upon gastrointestinal and pancreatic peptides, including ghrelin, gastrin, cholecystokinin (cck), glucose-dependent insulinotropic hormone (gip), glucagon-like peptide 1 (glp-1), peptide yy (pyy), oxyntomodulin, insulin, glucagon and somatostatin. |
2016-12-13 |
2023-08-13 |
Not clear |
| Silke Otter, Eckhard Lammer. Exciting Times for Pancreatic Islets: Glutamate Signaling in Endocrine Cells. Trends in endocrinology and metabolism: TEM. vol 27. issue 3. 2016-12-13. PMID:26740469. |
it also signals extracellularly via glutamate receptors (ampa and nmda receptors) to modulate glucagon, insulin and somatostatin secretion, and islet cell survival. |
2016-12-13 |
2023-08-13 |
Not clear |
| Tanupriya Agrawal, Adam J Blau, Walter J Chwals, Arthur S Tischle. A Unique Case of Mediastinal Teratoma with Mature Pancreatic Tissue, Nesidioblastosis, and Aberrant Islet Differentiation: a Case Report and Literature Review. Endocrine pathology. vol 27. issue 1. 2016-11-14. PMID:26318442. |
immunohistochemical staining showed pronounced expression of pancreatic polypeptide, moderate expression of somatostatin and insulin and nearly complete absence of glucagon-containing cells. |
2016-11-14 |
2023-08-13 |
Not clear |