| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiang He, Bo Lin, Lei Kong, Jiawen Zhan. The potential mechanism of chemosensitive difference between 2 types of ovarian cancer. Saudi medical journal. vol 28. issue 7. 2007-08-31. PMID:17603707. |
to study the potential molecular mechanism of chemosensitive difference between human malignant epithelial and germ cell tumor of the ovary by testing the expression of p53 (mutation), bcl-2, topoisomerase ii alpha (topo ii alpha). |
2007-08-31 |
2023-08-12 |
human |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
g alpha 12/13 basally regulates p53 through mdm4 expression. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
in view of the control of g alpha(12/13) in cell proliferation, this study investigated the role of g alpha(12/13) in the regulation of p53 and mdm4. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
g alpha(12) deficiency decreased p53 levels and its dna binding activity, accompanying p21 repression with bcl(2) induction, whereas g alpha(13) deficiency exerted weak effects. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
g alpha(12) or g alpha(13) deficiency did not change p53 mrna expression. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
erk1/2 or akt was not responsible for p53 repression due to g alpha(12) deficiency. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
p53 accumulation by proteasomal inhibition during g alpha(12) deficiency suggested the role of g alpha(12) in p53 stabilization. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
constitutively active g alpha(12) (g alpha(12)ql) or g alpha(13) (g alpha(13)ql) promoted p53 accumulation with mdm4 induction in mcf10a cells. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
p53 accumulation by mdm4 overexpression, but no mdm4 induction by p53 overexpression, and small interfering rna knockdown verified the regulatory role of mdm4 for p53 downstream of g alpha(12/13). |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
in control or g alpha(12)/g alpha(13)-deficient cells, genotoxic stress led to p53 accumulation. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
g alpha(12/13)ql transfection failed to phosphorylate p53 at serines. |
2007-06-29 |
2023-08-12 |
Not clear |
| Mi-Sung Kim, Sang Min Lee, Won Dong Kim, Sung Hwan Ki, Aree Moon, Chang Ho Lee, Sang Geon Ki. G alpha 12/13 basally regulates p53 through Mdm4 expression. Molecular cancer research : MCR. vol 5. issue 5. 2007-06-29. PMID:17510313. |
our results indicate that g alpha(12/13) regulate basal p53 levels via mdm4, which constitutes a cell signaling pathway distinct from p53 phosphorylations elicited by genotoxic stress. |
2007-06-29 |
2023-08-12 |
Not clear |
| Miguel Martínez-Rodríguez, David Ramos, Pilar Soriano, Manish Subramaniam, Samuel Navarro, Antonio Llombart-Bosc. Poorly differentiated adenocarcinomas of prostate versus high-grade urothelial carcinoma of the bladder: a diagnostic dilemma with immunohistochemical evaluation of 2 cases. International journal of surgical pathology. vol 15. issue 2. 2007-05-24. PMID:17478786. |
in both cases, a large panel of immunohistochemical markers were used and demonstrated positivity for prostate-specific antigen and alpha methyl racemase in the prostatic carcinomas and immunoreactivity for ck7, ck20, ag 34betae12, and p53 in the urothelial carcinoma. |
2007-05-24 |
2023-08-12 |
Not clear |
| Judah Folkma. Tumor suppression by p53 is mediated in part by the antiangiogenic activity of endostatin and tumstatin. Science's STKE : signal transduction knowledge environment. vol 2006. issue 354. 2007-05-10. PMID:17003465. |
recent research shows that p53 suppresses tumor angiogenesis by transcriptionally activating the alpha(ii) collagen prolyl-4-hydroxylase gene. |
2007-05-10 |
2023-08-12 |
Not clear |
| Daniela Uberti, Giulia Ferrari-Toninelli, Sara Anna Bonini, Ilenia Sarnico, Marina Benarese, Marina Pizzi, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, PierFranco Spano, Fabio Facchetti, Maurizio Mem. Blockade of the tumor necrosis factor-related apoptosis inducing ligand death receptor DR5 prevents beta-amyloid neurotoxicity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 4. 2007-05-01. PMID:16936710. |
in addition, the increased expression of dr5 receptor after beta amyloid treatment was sustained by p53 transcriptional activity, as demonstrated by the data showing that the p53 inhibitor pifithrin alpha prevented both beta amyloid-induced dr5 induction and cell death. |
2007-05-01 |
2023-08-12 |
Not clear |
| Lilach Weisz, Alexander Damalas, Michalis Liontos, Panagiotis Karakaidos, Giulia Fontemaggi, Revital Maor-Aloni, Marina Kalis, Massimo Levrero, Sabrina Strano, Vassilis G Gorgoulis, Varda Rotter, Giovanni Blandino, Moshe Ore. Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells. Cancer research. vol 67. issue 6. 2007-04-19. PMID:17363555. |
mutant p53 enhances nuclear factor kappab activation by tumor necrosis factor alpha in cancer cells. |
2007-04-19 |
2023-08-12 |
human |
| Lilach Weisz, Alexander Damalas, Michalis Liontos, Panagiotis Karakaidos, Giulia Fontemaggi, Revital Maor-Aloni, Marina Kalis, Massimo Levrero, Sabrina Strano, Vassilis G Gorgoulis, Varda Rotter, Giovanni Blandino, Moshe Ore. Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells. Cancer research. vol 67. issue 6. 2007-04-19. PMID:17363555. |
we now report that cancer-associated mutant p53 can augment the induction of nuclear factor kappab (nfkappab) transcriptional activity in response to the cytokine tumor necrosis factor alpha (tnfalpha). |
2007-04-19 |
2023-08-12 |
human |
| Sandeep Singh, Ankur Kumar Upadhyay, Amrendra Kumar Ajay, Manoj Kumar Bha. p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis. FEBS letters. vol 581. issue 2. 2007-03-20. PMID:17208232. |
abrogation of p53 transactivation activity by pifithrin alpha or dominant-negative mutant of p53 resulted in decrease in activation of erk in carb treated cells. |
2007-03-20 |
2023-08-12 |
human |
| E Y Cho, Y L Choi, S W Chae, J H Sohn, G H Ah. Relationship between p53-associated proteins and estrogen receptor status in ovarian serous neoplasms. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 16. issue 3. 2007-02-27. PMID:16803476. |
we studied the immunoexpression of p14arf, mdm2, and p53, in addition to relationships between those protein expressions and estrogen receptor (er)alpha in ovarian serous tumors including benign (n= 23), borderline (n= 41), and malignant (n= 94). |
2007-02-27 |
2023-08-12 |
Not clear |
| Francesca Angiero, Angelo Sidoni, Michele Stefan. Liposarcoma of the oral cavity--case reports of the pleomorphic and the dedifferentiated variants and a review of the literature. Anticancer research. vol 26. issue 6C. 2007-01-23. PMID:17214352. |
the second case it was intensely positive for p53, mib-1, s-100, and focal positive for mdm2, but negative for alpha smooth muscle actin, cd34, cd68 and desmin. |
2007-01-23 |
2023-08-12 |
Not clear |