| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flavie Kersanté, Jin-Ya Wang, Jin-Chung Chen, Catherine Mollereau, Jean-Marie Zaja. Anti-opioid effects of neuropeptide FF receptors in the ventral tegmental area. Neuroscience letters. vol 488. issue 3. 2011-05-02. PMID:21111027. |
dnpa decreased systemic morphine-induced elevation of dopamine and serotonin metabolites within the nac. |
2011-05-02 |
2023-08-12 |
rat |
| Nanna Hovelsø, Thomas Nicolaj Sager, Arne Mør. Combination of escitalopram and a 5-HT(₁A) receptor antagonist selectively decreases the extracellular levels of dopamine in the nucleus accumbens relative to striatum through 5-HT(₂C) receptor stimulation; suggestive of antipsychotic potential. Pharmacology, biochemistry, and behavior. vol 97. issue 3. 2011-04-11. PMID:20937301. |
in addition, it was demonstrated that escitalopram, in combination with the partial 5-ht(₁a) agonist, (-)-pindolol, decreased basal da levels in the nac. |
2011-04-11 |
2023-08-12 |
rat |
| Thibaut Sesia, Vincent Bulthuis, Sonny Tan, Lee Wei Lim, Rinske Vlamings, Arjan Blokland, Harry W M Steinbusch, Trevor Sharp, Veerle Visser-Vandewalle, Yasin Teme. Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin. Experimental neurology. vol 225. issue 2. 2010-10-01. PMID:20615406. |
in addition, in a second experiment, the effect of dbs of the nac core and shell on extracellular dopamine and serotonin levels was assessed in the nac and medial prefrontal cortex. |
2010-10-01 |
2023-08-12 |
human |
| Thibaut Sesia, Vincent Bulthuis, Sonny Tan, Lee Wei Lim, Rinske Vlamings, Arjan Blokland, Harry W M Steinbusch, Trevor Sharp, Veerle Visser-Vandewalle, Yasin Teme. Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin. Experimental neurology. vol 225. issue 2. 2010-10-01. PMID:20615406. |
these effects were associated with increased levels of dopamine and serotonin in the nac, but not in the medial prefrontal cortex. |
2010-10-01 |
2023-08-12 |
human |
| Thibaut Sesia, Vincent Bulthuis, Sonny Tan, Lee Wei Lim, Rinske Vlamings, Arjan Blokland, Harry W M Steinbusch, Trevor Sharp, Veerle Visser-Vandewalle, Yasin Teme. Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin. Experimental neurology. vol 225. issue 2. 2010-10-01. PMID:20615406. |
our data point out that dbs of the nac shell has negative effects on impulsive action which is accompanied by increases of dopamine and serotonin levels in the nac, whereas dbs of the nac core has beneficial behavioral effects. |
2010-10-01 |
2023-08-12 |
human |
| Agnieszka Krzyzosiak, Monika Szyszka-Niagolov, Marta Wietrzych, Serge Gobaille, Shin-ichi Muramatsu, Wojciech Kreze. Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice. Neuron. vol 66. issue 6. 2010-08-06. PMID:20620876. |
we show here that ablation of rxrgamma in mice leads to depressive-like behaviors including increased despair and anhedonia, which were accompanied by reduced expression of dopamine d2 receptor in the shell of nucleus accumbens (nac) and altered serotonin signaling. |
2010-08-06 |
2023-08-12 |
mouse |
| Agnieszka Krzyzosiak, Monika Szyszka-Niagolov, Marta Wietrzych, Serge Gobaille, Shin-ichi Muramatsu, Wojciech Kreze. Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice. Neuron. vol 66. issue 6. 2010-08-06. PMID:20620876. |
while abnormal serotonin signaling is not sufficient to generate the depressive behaviors, increasing d2r expression by chronic fluoxetine (prozac) treatment or adenoassociated virus type2 (aav2) mediated expression of rxrgamma or d2r in the nac of rxrgamma(-/-) mice normalizes depressive-like behaviors in rxrgamma(-/-) animals. |
2010-08-06 |
2023-08-12 |
mouse |
| Yukihiko Shirayama, Shigeyuki Chak. Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents. Current neuropharmacology. vol 4. issue 4. 2010-06-10. PMID:18654637. |
first, we discuss the roles of several neurotransmitters and neuropeptides in the functioning of the nac, including dopamine, glutamate, gamma-aminobutyric acid (gaba), acetylcholine, serotonin, dynorphin, enkephaline, brain-derived neurotrophic factor (bdnf), camp response element-binding protein (creb), melanin-concentrating hormone (mch) and cocaine- and amphetamine-regulated transcript (cart). |
2010-06-10 |
2023-08-12 |
Not clear |
| N Kitanaka, J Kitanaka, K Watabe, M Takemur. Low-dose pretreatment with clorgyline decreases the levels of 3-methoxy-4-hydroxyphenylglycol in the striatum and nucleus accumbens and attenuates methamphetamine-induced conditioned place preference in rats. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19958817. |
clorgyline at doses of 1.0 or 10 mg/kg significantly affected the tissue levels of 3,4-dihydroxyphenylacetic acid, norepinephrine (ne), mhpg, and serotonin in the cerebral cortex and those of all monoamines and metabolites examined in the striatum and nac. |
2010-03-12 |
2023-08-12 |
rat |
| Vasileios Boulougouris, Trevor W Robbin. Enhancement of spatial reversal learning by 5-HT2C receptor antagonism is neuroanatomically specific. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089901. |
the roles of 5-ht(2c) and 5-ht(2a) receptors were examined within some of the brain regions implicated in cognitive flexibility, namely the orbitofrontal cortex (ofc), medial prefrontal cortex (mpfc), and nucleus accumbens (nac), by means of targeted infusions of selective 5-ht(2c) and 5-ht(2a) receptor antagonists (sb 242084 and m100907, respectively). |
2010-02-05 |
2023-08-12 |
Not clear |
| Susan M Ferguson, Nolan A Sandygren, John F Neumaie. Pairing mild stress with increased serotonin-1B receptor expression in the nucleus accumbens increases susceptibility to amphetamine. The European journal of neuroscience. vol 30. issue 8. 2010-01-05. PMID:19817843. |
in order to examine how these factors interact to influence the development of behaviors associated with addiction, we used viral-mediated gene transfer to transiently increase expression of 5-ht(1b) receptors in the nucleus accumbens (nac) shell along with exposure to repeated mild stress (novelty + saline injection) in rats. |
2010-01-05 |
2023-08-12 |
rat |
| Susan M Ferguson, Nolan A Sandygren, John F Neumaie. Pairing mild stress with increased serotonin-1B receptor expression in the nucleus accumbens increases susceptibility to amphetamine. The European journal of neuroscience. vol 30. issue 8. 2010-01-05. PMID:19817843. |
we report that the increasing expression of 5-ht(1b) receptors on the terminals of nac shell neurons that project to the ventral tegmental area and repeatedly exposing rats to mild stress subsequently enhance the acute locomotor-activating effects of amphetamine. |
2010-01-05 |
2023-08-12 |
rat |
| Susan M Ferguson, Nolan A Sandygren, John F Neumaie. Pairing mild stress with increased serotonin-1B receptor expression in the nucleus accumbens increases susceptibility to amphetamine. The European journal of neuroscience. vol 30. issue 8. 2010-01-05. PMID:19817843. |
these results suggest that serotonin signaling through nac 5-ht(1b) heteroreceptors can interact with stress to increase susceptibility to the enduring forms of drug-induced plasticity that are associated with addiction. |
2010-01-05 |
2023-08-12 |
rat |
| Gian Marco Leggio, Adeline Cathala, Delphine Moison, Kathryn A Cunningham, Pier Vincenzo Piazza, Umberto Spampinat. Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens. Neuropharmacology. vol 56. issue 2. 2009-07-01. PMID:18977370. |
a functional balance between excitatory and inhibitory control over dopamine (da)-dependent behavioral and neurochemical effects of cocaine is afforded by the serotonin(2c) receptor (5-ht(2c)r) located within the ventral tegmental area and the nucleus accumbens (nac). |
2009-07-01 |
2023-08-12 |
rat |
| Gian Marco Leggio, Adeline Cathala, Delphine Moison, Kathryn A Cunningham, Pier Vincenzo Piazza, Umberto Spampinat. Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens. Neuropharmacology. vol 56. issue 2. 2009-07-01. PMID:18977370. |
the 5-ht(2c)r located in the medial prefrontal cortex (mpfc) has also been shown to inhibit cocaine-induced behaviors perhaps through inhibition of da function in the nac. |
2009-07-01 |
2023-08-12 |
rat |
| Gian Marco Leggio, Adeline Cathala, Delphine Moison, Kathryn A Cunningham, Pier Vincenzo Piazza, Umberto Spampinat. Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens. Neuropharmacology. vol 56. issue 2. 2009-07-01. PMID:18977370. |
using in vivo microdialysis in halothane-anesthetized rats, we tested this hypothesis by assessing the influence of mpfc 5-ht(2c)rs on cocaine-induced da outflow in the nac shell. |
2009-07-01 |
2023-08-12 |
rat |
| Linda A W Verhagen, Mieneke C M Luijendijk, Gerdien A H Korte-Bouws, S Mechiel Korte, Roger A H Ada. Dopamine and serotonin release in the nucleus accumbens during starvation-induced hyperactivity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 19. issue 5. 2009-06-05. PMID:19181487. |
here we determined dopamine and serotonin levels in the nac upon exposure to the aba model. |
2009-06-05 |
2023-08-12 |
rat |
| Linda A W Verhagen, Mieneke C M Luijendijk, Gerdien A H Korte-Bouws, S Mechiel Korte, Roger A H Ada. Dopamine and serotonin release in the nucleus accumbens during starvation-induced hyperactivity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 19. issue 5. 2009-06-05. PMID:19181487. |
surprisingly, the release of dopamine and serotonin in the nac were not increased during the initiation of food-anticipatory behavior in aba rats. |
2009-06-05 |
2023-08-12 |
rat |
| J L Lukkes, C H Summers, J L Scholl, K J Renner, G L Forste. Early life social isolation alters corticotropin-releasing factor responses in adult rats. Neuroscience. vol 158. issue 2. 2009-04-15. PMID:19010398. |
we tested the hypothesis that the stress of early life isolation enhances responses to crf in adulthood by determining the effect of crf infusions into the dorsal raphe nucleus (drn) on 5-ht release in the nucleus accumbens (nac) of adult rats using in vivo microdialysis. |
2009-04-15 |
2023-08-12 |
rat |
| J L Lukkes, C H Summers, J L Scholl, K J Renner, G L Forste. Early life social isolation alters corticotropin-releasing factor responses in adult rats. Neuroscience. vol 158. issue 2. 2009-04-15. PMID:19010398. |
following the isolation/re-socialization procedure, infusion of 100 ng crf into the drn decreased 5-ht release in the nac of group-reared rats. |
2009-04-15 |
2023-08-12 |
rat |