| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael G Bankson, Bryan K Yamamot. Serotonin-GABA interactions modulate MDMA-induced mesolimbic dopamine release. Journal of neurochemistry. vol 91. issue 4. 2005-05-25. PMID:15525339. |
these results suggest that mdma-mediated increases in da within the nac shell are dampened by increases in vta gaba subsequent to activation of 5-ht(2b/2c) receptors in the vta. |
2005-05-25 |
2023-08-12 |
rat |
| Yolanda Mateo, Evgeny A Budygin, Carrie E John, Matthew L Banks, Sara R Jone. Voltammetric assessment of dopamine clearance in the absence of the dopamine transporter: no contribution of other transporters in core or shell of nucleus accumbens. Journal of neuroscience methods. vol 140. issue 1-2. 2005-04-12. PMID:15589348. |
the present voltammetric study in brain slices was designed to examine the role of the norepinephrine and serotonin transporters in removing da from the extracellular space in the nac of dat-ko mice. |
2005-04-12 |
2023-08-12 |
mouse |
| A C Riegel, S F Ali, S Torinese, E D Frenc. Repeated exposure to the abused inhalant toluene alters levels of neurotransmitters and generates peroxynitrite in nigrostriatal and mesolimbic nuclei in rat. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542760. |
here we examined the effects of seven daily intraperitoneal injections of 600 mg/kg toluene on the content of serotonin and dopamine in the caudate nucleus (cn) and nucleus accumbens (nac), substantia nigra, and ventral tegmental area at 2, 4, and 24 h after the last injection. |
2005-02-18 |
2023-08-12 |
rat |
| A C Riegel, S F Ali, S Torinese, E D Frenc. Repeated exposure to the abused inhalant toluene alters levels of neurotransmitters and generates peroxynitrite in nigrostriatal and mesolimbic nuclei in rat. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542760. |
toluene treatments increased dopamine levels in the cn and nac, and serotonin levels in cn, nac, and ventral tegmental area. |
2005-02-18 |
2023-08-12 |
rat |
| Hao-Wei Shen, Yoko Hagino, Hideaki Kobayashi, Keiko Shinohara-Tanaka, Kazutaka Ikeda, Hideko Yamamoto, Toshifumi Yamamoto, Klaus-Peter Lesch, Dennis L Murphy, F Scott Hall, George R Uhl, Ichiro Sor. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 10. 2004-11-22. PMID:15226739. |
to help determine mechanisms underlying these effects, we now report examination of baselines and drug-induced changes of extracellular dopamine (daex) and serotonin (5-ht(ex)) levels in microdialysates from nucleus accumbens (nac), caudate putamen (cpu), and prefrontal cortex (pfc) of wild-type, homozygous dat- or sert-ko and heterozygous or homozygous dat/sert double-ko mice, which are differentially rewarded by cocaine. |
2004-11-22 |
2023-08-12 |
mouse |
| Christian P Müller, Heike Thönnessen, Marilia Barros, Carlos Tomaz, Robert J Carey, Joseph P Husto. Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus. vol 14. issue 6. 2004-11-01. PMID:15318330. |
cocaine induces an increase in hippocampal and nucleus accumbens (nac) serotonin (5-ht) concentration parallel to locomotor activation. |
2004-11-01 |
2023-08-12 |
rat |
| Christian P Müller, Heike Thönnessen, Marilia Barros, Carlos Tomaz, Robert J Carey, Joseph P Husto. Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus. vol 14. issue 6. 2004-11-01. PMID:15318330. |
parallel to that, the cocaine-induced 5-ht increase was attenuated dose-dependently in the hippocampus but was left unaffected in the nac. |
2004-11-01 |
2023-08-12 |
rat |
| Christian P Müller, Heike Thönnessen, Marilia Barros, Carlos Tomaz, Robert J Carey, Joseph P Husto. Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus. vol 14. issue 6. 2004-11-01. PMID:15318330. |
the intra-hippocampal application of 8-oh-dpat affected neither behavioral activity nor 5-ht concentration in the hippocampus and in the nac. |
2004-11-01 |
2023-08-12 |
rat |
| Christian P Müller, Heike Thönnessen, Marilia Barros, Carlos Tomaz, Robert J Carey, Joseph P Husto. Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus. vol 14. issue 6. 2004-11-01. PMID:15318330. |
in accord with these findings, hippocampal 5-ht(1a)-receptors may not be directly involved in the regulation of spontaneous behavior or basal 5-ht concentration in the hippocampus and nac. |
2004-11-01 |
2023-08-12 |
rat |
| Christian P Müller, Heike Thönnessen, Marilia Barros, Carlos Tomaz, Robert J Carey, Joseph P Husto. Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT. Hippocampus. vol 14. issue 6. 2004-11-01. PMID:15318330. |
however, the results indicate an inhibitory role of hippocampal 5-ht(1a)-receptors in cocaine-induced hyperactivity and in the 5-ht increase evoked by cocaine in the hippocampus but not in the nac. |
2004-11-01 |
2023-08-12 |
rat |
| Lesley A Ricci, James R Stellar, Mark S Todtenkop. Subregion-specific down-regulation of 5-HT3 immunoreactivity in the nucleus accumbens shell during the induction of cocaine sensitization. Pharmacology, biochemistry, and behavior. vol 77. issue 3. 2004-10-22. PMID:15006451. |
however, cocaine also acts on the serotonin (5-ht) system, which has been shown to modulate psychostimulant-induced increases in motor behavior and da release in the nac. |
2004-10-22 |
2023-08-12 |
rat |
| Lesley A Ricci, James R Stellar, Mark S Todtenkop. Subregion-specific down-regulation of 5-HT3 immunoreactivity in the nucleus accumbens shell during the induction of cocaine sensitization. Pharmacology, biochemistry, and behavior. vol 77. issue 3. 2004-10-22. PMID:15006451. |
the present study examines 5-ht(3) receptors in the subdivisions of the nac in cocaine-sensitized rats. |
2004-10-22 |
2023-08-12 |
rat |
| Lesley A Ricci, James R Stellar, Mark S Todtenkop. Subregion-specific down-regulation of 5-HT3 immunoreactivity in the nucleus accumbens shell during the induction of cocaine sensitization. Pharmacology, biochemistry, and behavior. vol 77. issue 3. 2004-10-22. PMID:15006451. |
sections of the nac were processed for 5-ht(3) immunoreactivity (5-ht(3)-ir), and the number of puncta was quantified in each of the subregions of the shell, as well as the core of the accumbens. |
2004-10-22 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
the nucleus accumbens (nac) is an important structure for cocaine-induced hyperactivity and receives a dense serotonergic (5-ht) innervation. |
2004-09-28 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
previous studies showed that a systemic activation of 5-ht(1a) receptors potentiates cocaine-induced hyperlocomotion, but attenuates the cocaine-induced 5-ht increase in the nac. |
2004-09-28 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
in order to address the role of nac 5-ht(1a) receptors in the control of cocaine-induced and spontaneous behavioural activity and local 5-ht release, we used in vivo microdialysis in freely moving rats. |
2004-09-28 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
the 5-ht(1a)-receptor agonist, 8-oh-dpat (0, 1 and 10 microm), was applied locally into the nac by reverse dialysis followed by a cocaine (10 mg/kg) or saline i.p. |
2004-09-28 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
the nac 5-ht(1a)-receptor activation potentiated cocaine-induced hyperlocomotion, but attenuated rearing behaviour dose-dependently. |
2004-09-28 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
parallel to that, the cocaine-induced increase in nac 5-ht dialysate level was unaffected, as were the decreases in 5-hiaa and dopac dialysate levels after cocaine. |
2004-09-28 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
in saline treated rats, the local application of 8-oh-dpat into the nac affected neither spontaneous behavioural activity nor 5-ht, 5-hiaa or dopac dialysate levels in the nac. |
2004-09-28 |
2023-08-12 |
rat |