| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandra Jean, Grégory Conductier, Christine Manrique, Constantin Bouras, Philippe Berta, René Hen, Yves Charnay, Joël Bockaert, Valérie Compa. Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 41. 2007-11-28. PMID:17913892. |
collectively, these results demonstrate that 5-ht(4)r-mediated up-regulation of cart in the nac triggers the appetite-suppressant effects of ecstasy. |
2007-11-28 |
2023-08-12 |
mouse |
| Markus Storvik, Jari Tiihonen, Tuija Haukijärvi, Erkki Tupal. Nucleus accumbens serotonin transporters in alcoholics measured by whole-hemisphere autoradiography. Alcohol (Fayetteville, N.Y.). vol 40. issue 3. 2007-05-24. PMID:17418697. |
in this preliminary study, possible alterations of [3h]citalopram binding to serotonin transporter (sert) were evaluated in the nac of cloninger type 1 and 2 alcoholics (nine and seven subjects, respectively), and nonalcoholic controls (10 subjects) by human postmortem whole-hemisphere autoradiography. |
2007-05-24 |
2023-08-12 |
human |
| Michael J Watt, Gina L Forster, Wayne J Korzan, Kenneth J Renner, Cliff H Summer. Rapid neuroendocrine responses evoked at the onset of social challenge. Physiology & behavior. vol 90. issue 4. 2007-05-17. PMID:17187831. |
however, brief social challenge caused distinct rapid increases in amygdala and nucleus accumbens (nac) dopamine and serotonin levels. |
2007-05-17 |
2023-08-12 |
human |
| Caio M Moreira, Sueli Masson, Milene C Carvalho, Marcus L Brandã. Exploratory behaviour of rats in the elevated plus-maze is differentially sensitive to inactivation of the basolateral and central amygdaloid nuclei. Brain research bulletin. vol 71. issue 5. 2007-04-05. PMID:17259015. |
in the present study, we carried out an ethopharmacological analysis of the behaviour of rats submitted to the elevated plus-maze test together with analysis of the tissue content of monoamine dopamine (da) and serotonin (5-ht) and their metabolites in the dorsal hippocampus (dh), nucleus accumbens (nac) and dorsal striatum (ds) of animals injected with saline or muscimol (1.0 nmol/0.2 microl) into the bla or cea. |
2007-04-05 |
2023-08-12 |
rat |
| Caio M Moreira, Sueli Masson, Milene C Carvalho, Marcus L Brandã. Exploratory behaviour of rats in the elevated plus-maze is differentially sensitive to inactivation of the basolateral and central amygdaloid nuclei. Brain research bulletin. vol 71. issue 5. 2007-04-05. PMID:17259015. |
such effects of muscimol into the cea were accompanied by increases in 5-ht content of the dh, whereas corresponding injections into the bla caused a reduction in the da content of the nac. |
2007-04-05 |
2023-08-12 |
rat |
| Sylvia Navailles, Delphine Moison, Dimitri Ryczko, Umberto Spampinat. Region-dependent regulation of mesoaccumbens dopamine neurons in vivo by the constitutive activity of central serotonin2C receptors. Journal of neurochemistry. vol 99. issue 4. 2007-01-09. PMID:17018023. |
here, using in vivo microdialysis in halothane-anesthetized rats, we investigated the relative contribution of ventral tegmental area (vta) and nucleus accumbens shell (nac) 5-ht(2c)rs in the phasic/tonic control of accumbal da release, to specifically identify the nature (inhibition/excitation) of the control, and the role of the 5-ht(2c)r ca. |
2007-01-09 |
2023-08-12 |
rat |
| Sylvia Navailles, Delphine Moison, Dimitri Ryczko, Umberto Spampinat. Region-dependent regulation of mesoaccumbens dopamine neurons in vivo by the constitutive activity of central serotonin2C receptors. Journal of neurochemistry. vol 99. issue 4. 2007-01-09. PMID:17018023. |
these findings demonstrate that both vta and nac 5-ht(2c)rs participate in the inhibitory control exerted by 5-ht(2c)rs on accumbal da release, and that the nac shell may represent a primary action site for the ca of 5-ht(2c)rs. |
2007-01-09 |
2023-08-12 |
rat |
| Tanja Vihavainen, Jelena Mijatovic, T Petteri Piepponen, Raimo K Tuominen, Liisa Ahte. Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice. Behavioural brain research. vol 173. issue 1. 2006-10-12. PMID:16846651. |
in the present study mice withdrawn from a 7-week oral nicotine treatment were administered morphine, following which their locomotor activities were recorded and the concentrations of dopamine, 5-hydroxytryptamine (5-ht), noradrenaline and their metabolites were measured in the caudate putamen (cpu) and nucleus accumbens (nac). |
2006-10-12 |
2023-08-12 |
mouse |
| Tanja Vihavainen, Jelena Mijatovic, T Petteri Piepponen, Raimo K Tuominen, Liisa Ahte. Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice. Behavioural brain research. vol 173. issue 1. 2006-10-12. PMID:16846651. |
morphine (10 mg/kg s.c.) elevated dopamine and 5-ht metabolites to the same degree in the nac of the nicotine-withdrawn and the control mice. |
2006-10-12 |
2023-08-12 |
mouse |
| Christophe Wersinger, Milan Rusnak, Anita Sidh. Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein. The European journal of neuroscience. vol 24. issue 1. 2006-09-05. PMID:16882008. |
the negative modulation of sert activity by alpha-syn occurred through the non-abeta-amyloid component (nac) domain of alpha-syn (aa58-107); dna constructs encoding this region mimicked the full-length alpha-syn protein by decreasing [(3)h]5-ht uptake by the transporter. |
2006-09-05 |
2023-08-12 |
human |
| Xiang Yang Zhang, Priscilla Kehoe, Therese A Koste. Neonatal isolation alters estrous cycle effects on ventral striatal extracellular monoamine levels. Progress in neuro-psychopharmacology & biological psychiatry. vol 30. issue 3. 2006-07-19. PMID:16412549. |
now, we examine basal 5-ht, da, and norepinephrine (ne) levels in nucleus accumbens (nac) using in vivo microdialysis in adult male and female rats with or without iso experience. |
2006-07-19 |
2023-08-12 |
rat |
| Julie D Ross, David V Herin, Paul S Frankel, Mary L Thomas, Kathryn A Cunningha. Chronic treatment with a serotonin(2) receptor (5-HT(2)R) agonist modulates the behavioral and cellular response to (+)-3,4-methylenedioxymethamphetamine [(+)-MDMA]. Drug and alcohol dependence. vol 81. issue 2. 2006-06-09. PMID:16054778. |
these data also suggest that expression of the 5-ht(2a)r in the nac and pfc may play a role in the sensitivity to the locomotor-stimulating effects of (+)-mdma and in the processes of neural regulation upon repeated psychostimulant administration. |
2006-06-09 |
2023-08-12 |
human |
| Zhu Li, Junji Ichikawa, Mei Huang, Adam J Prus, Jin Dai, Herbert Y Meltze. ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Psychopharmacology. vol 183. issue 2. 2006-04-13. PMID:16220333. |
previous studies from this laboratory using microdialysis have shown that pretreatment of the 5-ht(2a) antagonist m100907 with the typical apd and d(2) antagonist haloperidol produced an increase in the medial prefrontal cortex (mpfc), but not in the nucleus accumbens (nac), da release. |
2006-04-13 |
2023-08-12 |
rat |
| Zhu Li, Junji Ichikawa, Mei Huang, Adam J Prus, Jin Dai, Herbert Y Meltze. ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Psychopharmacology. vol 183. issue 2. 2006-04-13. PMID:16220333. |
however, pretreatment with the 5-ht(2a/2c) receptor antagonist sr46349-b with haloperidol increased both mpfc and nac da release, suggesting that both 5-ht(2a) and 5-ht(2c) properties may be important for atypical apd effects. |
2006-04-13 |
2023-08-12 |
rat |
| William A Carlezon, Cécile Béguin, Jennifer A DiNieri, Michael H Baumann, Michele R Richards, Mark S Todtenkopf, Richard B Rothman, Zhongze Ma, David Y-W Lee, Bruce M Cohe. Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats. The Journal of pharmacology and experimental therapeutics. vol 316. issue 1. 2006-03-31. PMID:16223871. |
at a dose that caused the depressive-like effects in both the fst and icss assays, salva decreased extracellular concentrations of dopamine (da) within the nucleus accumbens (nac), a critical component of brain reward circuitry, without affecting extracellular concentrations of serotonin (5-ht). |
2006-03-31 |
2023-08-12 |
rat |
| Daniel G Smith, Eleni T Tzavara, Janice Shaw, Susan Luecke, Mark Wade, Richard Davis, Craig Salhoff, George G Nomikos, Donald R Gehler. Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 4. 2005-08-31. PMID:15673672. |
basal and amphetamine-evoked nac dopamine, norepinephrine, and serotonin efflux, as measured using in vivo microdialysis, were not significantly different between genotypes. |
2005-08-31 |
2023-08-12 |
mouse |
| Daniel G Smith, Eleni T Tzavara, Janice Shaw, Susan Luecke, Mark Wade, Richard Davis, Craig Salhoff, George G Nomikos, Donald R Gehler. Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 4. 2005-08-31. PMID:15673672. |
norepinephrine transporter (net) binding was significantly elevated within the nac shell and globus pallidus of ko mice, whereas serotonin transporter binding was decreased in the nac shell. |
2005-08-31 |
2023-08-12 |
mouse |
| Esther O'Shea, Isabel Escobedo, Laura Orio, Veronica Sanchez, Miguel Navarro, A Richard Green, M Isabel Colad. Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 7. 2005-08-09. PMID:15688085. |
we examined the effect of ambient room temperature (20 and 30 degrees c) on mdma-induced dopamine and 5-ht efflux in the striatum and shell of nucleus accumbens (nac) of freely moving rats by using microdialysis. |
2005-08-09 |
2023-08-12 |
rat |
| Catharine A Winstanley, David E H Theobald, Jeffrey W Dalley, Trevor W Robbin. Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 4. 2005-07-28. PMID:15688093. |
these data suggest a significant role for 5-ht : da interactions within the nac in the control of impulsivity, and in the mechanism by which amphetamine decreases impulsive choice. |
2005-07-28 |
2023-08-12 |
human |
| Michael G Bankson, Bryan K Yamamot. Serotonin-GABA interactions modulate MDMA-induced mesolimbic dopamine release. Journal of neurochemistry. vol 91. issue 4. 2005-05-25. PMID:15525339. |
the selective da releaser d-amphetamine (amph) (4 mg/kg) also increased vta gaba efflux (180%), did not alter 5-ht and increased nac da (875%) (p < 0.05), but the perfusion of sb 206553 into the vta failed to alter these effects. |
2005-05-25 |
2023-08-12 |
rat |