| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Milene C Carvalho, Caio M Moreira, Janaína M Zanoveli, Marcus L Brandã. Central, but not basolateral, amygdala involvement in the anxiolytic-like effects of midazolam in rats in the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:21148026. |
in the present study, we ethopharmacologically analyzed the behavior of rats subjected to the epm and the tissue content of the monoamines dopamine (da) and serotonin (5-ht) and their metabolites in the nucleus accumbens (nac), dorsal hippocampus (dh), and dorsal striatum (ds) of animals injected with saline or midazolam (20 and 30 nmol/0.2 µl) into the bla or cea. |
2012-08-17 |
2023-08-12 |
rat |
| Milene C Carvalho, Caio M Moreira, Janaína M Zanoveli, Marcus L Brandã. Central, but not basolateral, amygdala involvement in the anxiolytic-like effects of midazolam in rats in the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:21148026. |
these treatments did not cause significant changes in 5-ht or da contents in the nac, dh, or ds of animals tested in the epm. |
2012-08-17 |
2023-08-12 |
rat |
| Addy van Dijk, Oliver Mason, Andre A Klompmakers, Matthijs G P Feenstra, Damiaan Deny. Unilateral deep brain stimulation in the nucleus accumbens core does not affect local monoamine release. Journal of neuroscience methods. vol 202. issue 2. 2012-08-16. PMID:21565219. |
freely moving animals were unilaterally stimulated with 300 μa or 400 μa (120 hz, pulse width 80 μs) in the nac core for 5 h. 1h before and during stimulation we measured dopamine, serotonin, their metabolites and noradrenaline using in vivo microdialysis. |
2012-08-16 |
2023-08-12 |
Not clear |
| In-Jee You, Yang-Hee Jung, Min-Jung Kim, Seung-Hwan Kwon, Sa-Ik Hong, Seok-Yong Lee, Choon-Gon Jan. Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT₁A, GABA(A), and NMDA receptors. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22074644. |
binding of [(3)h]-8-oh-dpat was significantly higher in the frontal associated cortex (fra), nucleus accumbens (nac), and the cingulate cortex (cc) of trpv1ko mice than wt mice, while the expression of 5-ht(1a) receptors was higher in the fra, nac, and cortex of trpv1ko mice than wt mice. |
2012-07-27 |
2023-08-12 |
mouse |
| Viviane M Linck, Luciane Costa-Campos, Luísa K Pilz, Cícero R L Garcia, Elaine Elisabetsk. AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test. Behavioural pharmacology. vol 23. issue 2. 2012-07-16. PMID:22327021. |
the aim of this study was to investigate the involvement of noradrenaline, serotonin, and subtypes of glutamate receptors in the antidepressant-like effects of n-acetylcysteine (nac). |
2012-07-16 |
2023-08-12 |
mouse |
| Viviane M Linck, Luciane Costa-Campos, Luísa K Pilz, Cícero R L Garcia, Elaine Elisabetsk. AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test. Behavioural pharmacology. vol 23. issue 2. 2012-07-16. PMID:22327021. |
like other ampa potentiators, nac indirectly modulates noradrenaline and serotonin pathways. |
2012-07-16 |
2023-08-12 |
mouse |
| Paolo Tucci, Maria Grazia Morgese, Marilena Colaianna, Margherita Zotti, Stefania Schiavone, Vincenzo Cuomo, Luigia Trabac. Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes. Steroids. vol 77. issue 3. 2012-05-11. PMID:22197661. |
twenty-four hours after last injection, changes of dopamine (da) and relative metabolite levels, homovanilic acid (hva) and 3,4-dihydroxy phenylacetic acid (dopac), serotonin (5-ht) and its metabolite levels, 5-hydroxy indolacetic acid (5-hiaa), and noradrenaline (na) amount were investigated in prefrontal cortex (pfc), nucleus accumbens (nac), striatum (str) and hippocampus (hipp). |
2012-05-11 |
2023-08-12 |
rat |
| Dave J Hayes, John Hoang, Andrew J Greensha. The role of nucleus accumbens shell GABA receptors on ventral tegmental area intracranial self-stimulation and a potential role for the 5-HT(2C) receptor. Journal of psychopharmacology (Oxford, England). vol 25. issue 12. 2012-04-26. PMID:21169393. |
these results suggest that a 5-ht(2c) and gaba(a) receptor-mediated neuronal relationship in the nac shell may be relevant for the regulation of brain reward pathways. |
2012-04-26 |
2023-08-12 |
Not clear |
| Bradley J Martin, Bartholomew J Naughton, Keerthi Thirtamara-Rajamani, Daniel J Yoon, Dawn D Han, A Courtney Devries, Howard H G. Dopamine transporter inhibition is necessary for cocaine-induced increases in dendritic spine density in the nucleus accumbens. Synapse (New York, N.Y.). vol 65. issue 6. 2012-03-12. PMID:20936687. |
however, how cocaine increases dendritic spine density in the nac has been difficult to discern because cocaine inhibits the function of multiple targets, including the transporters for dopamine, serotonin, and norepinephrine. |
2012-03-12 |
2023-08-12 |
mouse |
| Kristen A Horner, Yamiece E Gilbert, Erika S Nobl. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine. Brain research. vol 1390. 2012-03-07. PMID:21420940. |
the goal of the current study was to determine the effects of chronic, escalating doses of d-amphetamine (d-amph) and withdrawal on the expression of 5-ht(2a) receptors in the cortex, caudate putamen, nac and hippocampus of rat brain. |
2012-03-07 |
2023-08-12 |
rat |
| Kristen A Horner, Yamiece E Gilbert, Erika S Nobl. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine. Brain research. vol 1390. 2012-03-07. PMID:21420940. |
chronic, escalating doses of d-amph, followed by a 24 h withdrawal period, significantly decreased 5-ht(2a) receptor mrna expression in the prefrontal, motor and cingulate cortices, while 5-ht(2a) receptor mrna expression in the nac, caudal cpu and hippocampus were significantly increased. |
2012-03-07 |
2023-08-12 |
rat |
| Xiao Han, Weiwen Wang, Feng Shao, Nanxin L. Isolation rearing alters social behaviors and monoamine neurotransmission in the medial prefrontal cortex and nucleus accumbens of adult rats. Brain research. vol 1385. 2012-02-14. PMID:21338587. |
isolation-reared rats also manifested increased dopamine and serotonin levels in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) as well as an increase in serotonin turnover in the nac. |
2012-02-14 |
2023-08-12 |
rat |
| Amy R Furay, Ross A McDevitt, Klaus A Miczek, John F Neumaie. 5-HT1B mRNA expression after chronic social stress. Behavioural brain research. vol 224. issue 2. 2011-12-21. PMID:21718722. |
the 5-ht(1b) receptor is expressed in nucleus accumbens (nac) projection neurons and modulates drug reward mechanisms and there is evidence suggesting that stress alters the regulation and function of these receptors. |
2011-12-21 |
2023-08-12 |
rat |
| María Juliana Orejarena, Laurence Lanfumey, Rafael Maldonado, Patricia Robled. Involvement of 5-HT2A receptors in MDMA reinforcement and cue-induced reinstatement of MDMA-seeking behaviour. The international journal of neuropsychopharmacology. vol 14. issue 7. 2011-11-10. PMID:20942998. |
basal and mdma-stimulated extracellular levels of da in the nucleus accumbens (nac) and serotonin and noradrenaline in the prefrontal cortex were also assessed. |
2011-11-10 |
2023-08-12 |
mouse |
| Marcy J Bubar, Sonja J Stutz, Kathryn A Cunningha. 5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathway. PloS one. vol 6. issue 6. 2011-10-14. PMID:21687728. |
here, we employed double-label fluorescence immunochemistry with the synthetic enzymes for dopamine (tyrosine hydroxylase; th) and gaba (glutamic acid decarboxylase isoform 67; gad-67) and retrograde tract tracing with fluorogold (fg) to uncover whether dopamine and gaba vta neurons that possess 5-ht(2c)r innervate the nucleus accumbens (nac). |
2011-10-14 |
2023-08-12 |
rat |
| Marcy J Bubar, Sonja J Stutz, Kathryn A Cunningha. 5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathway. PloS one. vol 6. issue 6. 2011-10-14. PMID:21687728. |
thus, we demonstrate for the first time that the 5-ht(2c)r colocalizes in da and gaba vta neurons which project to the nac, describe in detail the distribution of nac-projecting gaba vta neurons, and identify the colocalization of th and gad-67 in the same nac-projecting vta neurons. |
2011-10-14 |
2023-08-12 |
rat |
| Marcy J Bubar, Sonja J Stutz, Kathryn A Cunningha. 5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathway. PloS one. vol 6. issue 6. 2011-10-14. PMID:21687728. |
these data suggest that the 5-ht(2c)r may exert direct influence upon both dopamine and gaba vta output to the nac. |
2011-10-14 |
2023-08-12 |
rat |
| Avi E Zayara, Gregor McIver, Paola N Valdivia, Kevin D Lominac, Andrew C McCreary, Karen K Szumlinsk. Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in rats. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20814782. |
the serotonin 5-ht(2a) and 5-ht(2c) receptors regulate the capacity of acute cocaine to augment behavior and monoamine levels within the nucleus accumbens (nac), a brain region involved in cocaine's addictive and psychotogenic properties. |
2011-05-24 |
2023-08-12 |
rat |
| V Valentini, R Frau, F Bordi, F Borsini, G Di Chiar. A microdialysis study of ST1936, a novel 5-HT6 receptor agonist. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21185318. |
here we report the effect of st1936 (5-10-20 mg/kg/ip) on dialysate da, na and 5-ht in the medial prefrontal cortex (pfcx) and in the shell and core of the nucleus accumbens (nac). |
2011-05-12 |
2023-08-12 |
Not clear |
| Flavie Kersanté, Jin-Ya Wang, Jin-Chung Chen, Catherine Mollereau, Jean-Marie Zaja. Anti-opioid effects of neuropeptide FF receptors in the ventral tegmental area. Neuroscience letters. vol 488. issue 3. 2011-05-02. PMID:21111027. |
a stable npff(2) receptor agonist, dnpa, was injected into the ventral tegmental area (vta) and the release of dopamine and serotonin within the nucleus accumbens (nac), induced by intraperitoneal injection of morphine, was monitored using the brain microdialysis, in non-constrained rat. |
2011-05-02 |
2023-08-12 |
rat |