| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| William H Hoffman, Cornelia D Cudrici, Dallas Boodhoo, Alexandru Tatomir, Violeta Rus, Horea Ru. Intracerebral matrix metalloproteinase 9 in fatal diabetic ketoacidosis. Experimental and molecular pathology. vol 108. 2020-02-14. PMID:30986397. |
based on our previous studies, we address the question if matrix metalloproteinase 9 (mmp9) is expressed in the brain in the fatal brain edema (be) of dka. |
2020-02-14 |
2023-08-13 |
human |
| Per Larsson, Azharuddin Sajid Syed Khaja, Julius Semenas, Tianyan Wang, Martuza Sarwar, Nishtman Dizeyi, Athanasios Simoulis, Andreas Hedblom, Sun Nyunt Wai, Niels Ødum, Jenny L Persso. The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer. International journal of cancer. vol 146. issue 6. 2020-02-14. PMID:31381135. |
given that matrix metalloproteinases 9 (mmp9) and its associated vascular endothelial growth factor (vegf) are critical for tumor vascularization and invasion under castration-resistant condition, it is therefore of great importance to define the functional association and interplay between androgen receptor (ar) and mmp9 and their associated key survival and invasion pathways in pca cells. |
2020-02-14 |
2023-08-13 |
Not clear |
| Fu-Lian Gong, Lei Wang, Lu-Gang Yu, Yi-Fan Dang, Xiao-Ning Jiang, Lin Zhao, Xiu-Li Gu. DHPAC, a novel microtubule depolymerizing agent, suppresses angiogenesis and vasculogenic mimicry formation of human non-small cell lung cancer. Journal of cellular biochemistry. 2020-02-14. PMID:32056279. |
in addition, dhpac inhibited the phosphorylation of fak and akt and decreased the expressions of vegf, matrix metalloproteinase 2 (mmp2), mmp9 and laminin 5, suggesting that dhpac inhibited vm formation via the fak/akt signaling pathway. |
2020-02-14 |
2023-08-13 |
human |
| Chang-Yong Wang, Min Shang, Chen-Liang Zhou, Li-Zhi Feng, Qing-Shan Zhou, Ke H. Mechanism of Cxc Chemokine Ligand 5 (CXCL5)/Cxc Chemokine Receptor 2 (CXCR2) Bio-Axis in Mice with Acute Respiratory Distress Syndrome. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-13. PMID:31311916. |
real-time pcr and western blot analysis were performed to detect the expression levels of cxcl5, cxcr2, matrix metalloproteinases 2 (mmp2), and matrix metalloproteinases 9 (mmp9) in lung tissues. |
2020-02-13 |
2023-08-13 |
mouse |
| Mary Sproull, Uma Shankavaram, Kevin Camphause. Comparison of Proteomic Biodosimetry Biomarkers Across Five Different Murine Strains. Radiation research. vol 192. issue 6. 2020-02-10. PMID:31618122. |
the current study seeks to compare the expression levels of five previously established proteomic biodosimetry biomarkers of radiation exposure, i.e., flt3 ligand (fl), matrix metalloproteinase 9 (mmp9), serum amyloid a (saa), pentraxin 3 (ptx3) and fibrinogen (fgb), across multiple murine strains and to test a multivariate dose prediction model based on a single c57bl6 strain against other murine strains. |
2020-02-10 |
2023-08-13 |
mouse |
| Xiao Guo, Chengzhan Zhu, Xiaojun Liu, Yiping Ge, Xianyan Jiang, Wei Zha. Hyperoside protects against heart failure-induced liver fibrosis in rats. Acta histochemica. vol 121. issue 7. 2020-02-06. PMID:31353051. |
further, α-smooth-muscle actin (α-sma), collagen i, profibrotic factor-connective tissue growth factor (ctgf), matrix metalloproteinase-2 (mmp2) and mmp9 levels were down-regulated in hyperoside-treated acf rats. |
2020-02-06 |
2023-08-13 |
rat |
| Yafei Chen, Xin Chen, Xiaojun Ding, Yingwei Wan. Afatinib, an EGFR inhibitor, decreases EMT and tumorigenesis of Huh‑7 cells by regulating the ERK‑VEGF/MMP9 signaling pathway. Molecular medicine reports. vol 20. issue 4. 2020-02-04. PMID:31432165. |
furthermore, the activity of the erk signaling pathway and the expression levels of vascular endothelial growth factor (vegf) and matrix metalloproteinase 9 (mmp9) were decreased following treatment with afatinib in vitro. |
2020-02-04 |
2023-08-13 |
Not clear |
| Xiaohu Nie, Yue Zhou, Xiaobing Li, Jie Xu, Xuyan Pan, Rui Yin, Bin L. Calycosin down-regulates c-Met to suppress development of glioblastomas. Journal of biosciences. vol 44. issue 4. 2020-01-30. PMID:31502574. |
meanwhile a western blot assay showed that c-met together with matrix metalloproteinases-9 (mmp9) and phosphorylation of the serine/threonine kinase akt (p-akt) was significantly down-regulated by calycosin. |
2020-01-30 |
2023-08-13 |
Not clear |
| Tan Li, Xu Zhang, Liang Sang, Xin-Tong Li, Hai-Yang Sun, Jun Yang, Yuan Yua. The interaction effects between TLR4 and MMP9 gene polymorphisms contribute to aortic aneurysm risk in a Chinese Han population. BMC cardiovascular disorders. vol 19. issue 1. 2020-01-29. PMID:30922233. |
a cross-talk between toll-like receptor 4 (tlr4) and matrix metalloproteinase 9 (mmp9) plays a vital role in aortic pathophysiology. |
2020-01-29 |
2023-08-13 |
Not clear |
| Yi-Chen Chen, Shih-Chieh Chang, Yu-Han Huang, Ya-Jane Lee, Chao-Chin Chang, Jiunn-Wang Liao, Wei-Li Hs. Expression and the molecular forms of neutrophil gelatinase-associated lipocalin and matrix metalloproteinase 9 in canine mammary tumours. Veterinary and comparative oncology. vol 17. issue 3. 2020-01-28. PMID:31050171. |
the oncogenic role of ngal is related to its molecular forms, and heterodimer formation with matrix metalloproteinase 9 (mmp9) promotes human breast cancer (hbc) invasion and metastasis. |
2020-01-28 |
2023-08-13 |
human |
| Yu Wang, Danyang Zhao, Xiao Wei, Lin Ma, Jing Sheng, Ping L. PEGylated Polyethylenimine Derivative-Mediated Local Delivery of the shSmad3 Inhibits Intimal Thickening after Vascular Injury. BioMed research international. vol 2019. 2020-01-28. PMID:31467913. |
moreover, peg-et 1:1/shsmad3 polyplex treatment significantly inhibited collagen, matrix metalloproteinase 1 (mmp1), mmp2 and mmp9 expression, and upregulated tissue inhibitor of metalloproteinase 1 (timp1) expression both |
2020-01-28 |
2023-08-13 |
Not clear |
| Jian Jiang, Na Shen, Tianyuan Ci, Zhaohui Tang, Zhen Gu, Gao Li, Xuesi Che. Combretastatin A4 Nanodrug-Induced MMP9 Amplification Boosts Tumor-Selective Release of Doxorubicin Prodrug. Advanced materials (Deerfield Beach, Fla.). vol 31. issue 44. 2020-01-24. PMID:31549774. |
a cooperative strategy that utilizes combretastatin a4 nanodrug (ca4-nps) and matrix metalloproteinase 9 (mmp9)-activated doxorubicin prodrug (mmp9-dox-nps) is developed. |
2020-01-24 |
2023-08-13 |
mouse |
| Li Tao, Yingjie Zhu, Ying Gu, Jian Zheng, Jinkun Yan. ARHGAP25: A negative regulator of colorectal cancer (CRC) metastasis via the Wnt/β-catenin pathway. European journal of pharmacology. vol 858. 2020-01-21. PMID:31228451. |
additionally, expression of matrix metalloproteinases (mmp2, mmp7 and mmp9), emt-associated factors (e-cadherin, zeb1, snail and twist1) and β-catenin (a core part of wnt/β-catenin signaling) was determined. |
2020-01-21 |
2023-08-13 |
Not clear |
| Ke Guo, Guo You Wang, Bao Ting Fan, Manoj Kumar Sah, Peng Yu Qu, Shan Yong Zhan. The effect of vascular endothelial growth factor (VEGF) on mouse condylar articular cartilage cultured in vitro. International journal of clinical and experimental pathology. vol 11. issue 11. 2020-01-21. PMID:31949599. |
the mankin score was used to evaluate changes to the condylar cartilage tissues, and immunohistochemistry was performed to observe the expressions of vegf receptor 2 (vegfr2), matrix metallopeptidase 9 (mmp9), matrix metallopeptidase 13 (mmp13), and tumor necrosis factor-related activation-induced cytokine (trance). |
2020-01-21 |
2023-08-13 |
mouse |
| Jianglong Feng, Wenxiu Yang, Jiarui Wang, Zhenhong Pu, Ying Han, Long Wa. Z-VRPR-FMK can inhibit the growth and invasiveness of diffuse large B-cell lymphoma by depressing NF-κB activation and MMP expression induced by MALT1. International journal of clinical and experimental pathology. vol 12. issue 6. 2020-01-17. PMID:31934017. |
the components of the nf-κb signaling pathways, such as p65, malt1, a20, matrix metalloproteinase 2 (mmp2) and mmp9, were detected using a real-time fluorescent quantitative polymerase chain reaction, immunohistochemical staining, and a western blot analysis. |
2020-01-17 |
2023-08-13 |
mouse |
| Sunaina Sapru, Subhayan Das, Mahitosh Mandal, Ananta K Ghosh, Subhas C Kund. Nonmulberry silk protein sericin blend hydrogels for skin tissue regeneration - in vitro and in vivo. International journal of biological macromolecules. vol 137. 2020-01-15. PMID:31220499. |
the in vitro analysis of the hydrogels showed enhanced adhesion, proliferation, and migration of skin cells with coordinated interaction amongst themselves leading to the synthesis of collagen iv and matrix metalloproteinase (mmp2 and mmp9). |
2020-01-15 |
2023-08-13 |
human |
| Zhen Zhou, Andrew M Peters, Shanzhi Wang, Alexandra Janda, Jiyuan Chen, Ping Zhou, Erin Arthur, Callie S Kwartler, Dianna M Milewic. Reversal of Aortic Enlargement Induced by Increased Biomechanical Forces Requires AT1R Inhibition in Conjunction With AT2R Activation. Arteriosclerosis, thrombosis, and vascular biology. vol 39. issue 3. 2020-01-13. PMID:30602301. |
an angiotensin-converting enzyme inhibitor, captopril, decreased systolic blood pressure to the same level as losartan but did not attenuate aortic dilation, adventitial inflammation, medial collagen deposition, elastin breakage, or mmp9 (matrix metalloproteinase-9) expression when compared with tac mice. |
2020-01-13 |
2023-08-13 |
mouse |
| Yulei Zhang, Xiaoqin Che. lncRNA FOXD2-AS1 affects trophoblast cell proliferation, invasion and migration through targeting miRNA. Zygote (Cambridge, England). 2020-01-13. PMID:31928563. |
western blotting was used to analyze the expression of matrix metalloproteinase 2 (mmp2) and matrix metalloproteinase 9 (mmp9). |
2020-01-13 |
2023-08-13 |
Not clear |
| Liu Liu, Ping Zhang, Zhaosi Zhang, Qin Hu, Junchi He, Han Liu, Jun Zhao, Yidan Liang, Zhaohui He, Xinghua Li, Xiaochuan Sun, Zongduo Gu. LXA4 ameliorates cerebrovascular endothelial dysfunction by reducing acute inflammation after subarachnoid hemorrhage in rats. Neuroscience. vol 408. 2020-01-09. PMID:30910642. |
the expression of lxa4 and its downstream molecules, formyl peptide receptor 2 (fpr2), extracellular signal-regulated kinase (erk1/2), nuclear factor-κb (nf-κb), matrix metalloproteinase-9 (mmp9), and the levels of pro-inflammatory cytokines (tnf-α, il-1β, il-6), leukocyte adhesion molecule (intercellular adhesion molecule-1, icam-1) and mpo were measured either by western blot or enzyme-linked immunosorbent assay (elisa). |
2020-01-09 |
2023-08-13 |
rat |
| Fengqi Yao, Zhangting Yao, Tiecheng Zhong, Jieqiong Zhang, Tingting Wang, Bo Zhang, Qiaojun He, Ling Ding, Bo Yan. Imatinib prevents elastase-induced abdominal aortic aneurysm progression by regulating macrophage-derived MMP9. European journal of pharmacology. vol 860. 2020-01-08. PMID:31325435. |
macrophage-derived mmp9 acts as a key factor in extracellular matrix degradation and is crucial for aortic aneurysm development and aortic rupture. |
2020-01-08 |
2023-08-13 |
rat |