| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Krupanandan Haranahalli, Tadashi Honda, Iwao Ojim. Recent progress in the strategic incorporation of fluorine into medicinally active compounds. Journal of fluorine chemistry. vol 217. 2020-02-25. PMID:31537946. |
this account exemplifies our recent progress on the strategic incorporation of fluorine and organofluorine groups to (i) taxoid anticancer agents, (ii) acylhydrazone-based antifungal agents and (iii) inhibitors of matrix metalloproteinase 9 (mmp9) for medicinal chemistry and chemical biology studies. |
2020-02-25 |
2023-08-13 |
Not clear |
| Julia Etich, Manuel Koch, Raimund Wagener, Frank Zaucke, Mario Fabri, Bent Brachvoge. Gene Expression Profiling of the Extracellular Matrix Signature in Macrophages of Different Activation Status: Relevance for Skin Wound Healing. International journal of molecular sciences. vol 20. issue 20. 2020-02-21. PMID:31615030. |
among those core matrisome and matrisome-associated components transforming growth factor beta (tgfβ)-induced, matrix metalloproteinase 9 (mmp9), elastin microfibril interfacer (emilin)-1, netrin-1 and gliomedin were also present within the wound bed at time points that are characterized by profound macrophage infiltration. |
2020-02-21 |
2023-08-13 |
Not clear |
| Shenzhi Zhao, Tingting Liao, Tong Zhou, Xianping Huang, Huiqiu Xiang, Jiajia Chen, Zhangye X. Formyl-peptide receptor 2 suppresses proliferation, migration and invasion in human extravillous trophoblastic cells. Prostaglandins & other lipid mediators. vol 143. 2020-02-19. PMID:31176799. |
in addition, fpr2 overexpression significantly decreased mrna and protein levels of integrin-linked kinase (ilk), nuclear factor-kappa b (nf--κb), matrix metalloproteinase 9 (mmp9) and vascular endothelial growth factor (vegf) in tev-1 cells. |
2020-02-19 |
2023-08-13 |
human |
| Masaki Ueno, Manabu Kawai, Jin-Young Park, Seiko Hirono, Ken-Ichi Okada, Shinya Hayami, Hee-Jung Wang, Hiroki Yamau. Prognostic Analysis of Hepatocellular Carcinoma With Hepatitis C Virus Infection Using Epithelial-Mesenchymal Transition Gene Profiles. The Journal of surgical research. vol 245. 2020-02-19. PMID:31421377. |
previously, the following four epithelial-mesenchymal transition-related genes were considered to be significantly influential: e-cadherin (cdh1), inhibitor of dna binding 2 (id2), matrix metalloproteinase 9 (mmp9), and transcription factor 3 (tcf3). |
2020-02-19 |
2023-08-13 |
Not clear |
| William H Hoffman, Cornelia D Cudrici, Dallas Boodhoo, Alexandru Tatomir, Violeta Rus, Horea Ru. Intracerebral matrix metalloproteinase 9 in fatal diabetic ketoacidosis. Experimental and molecular pathology. vol 108. 2020-02-14. PMID:30986397. |
based on our previous studies, we address the question if matrix metalloproteinase 9 (mmp9) is expressed in the brain in the fatal brain edema (be) of dka. |
2020-02-14 |
2023-08-13 |
human |
| Per Larsson, Azharuddin Sajid Syed Khaja, Julius Semenas, Tianyan Wang, Martuza Sarwar, Nishtman Dizeyi, Athanasios Simoulis, Andreas Hedblom, Sun Nyunt Wai, Niels Ødum, Jenny L Persso. The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer. International journal of cancer. vol 146. issue 6. 2020-02-14. PMID:31381135. |
given that matrix metalloproteinases 9 (mmp9) and its associated vascular endothelial growth factor (vegf) are critical for tumor vascularization and invasion under castration-resistant condition, it is therefore of great importance to define the functional association and interplay between androgen receptor (ar) and mmp9 and their associated key survival and invasion pathways in pca cells. |
2020-02-14 |
2023-08-13 |
Not clear |
| Fu-Lian Gong, Lei Wang, Lu-Gang Yu, Yi-Fan Dang, Xiao-Ning Jiang, Lin Zhao, Xiu-Li Gu. DHPAC, a novel microtubule depolymerizing agent, suppresses angiogenesis and vasculogenic mimicry formation of human non-small cell lung cancer. Journal of cellular biochemistry. 2020-02-14. PMID:32056279. |
in addition, dhpac inhibited the phosphorylation of fak and akt and decreased the expressions of vegf, matrix metalloproteinase 2 (mmp2), mmp9 and laminin 5, suggesting that dhpac inhibited vm formation via the fak/akt signaling pathway. |
2020-02-14 |
2023-08-13 |
human |
| Chang-Yong Wang, Min Shang, Chen-Liang Zhou, Li-Zhi Feng, Qing-Shan Zhou, Ke H. Mechanism of Cxc Chemokine Ligand 5 (CXCL5)/Cxc Chemokine Receptor 2 (CXCR2) Bio-Axis in Mice with Acute Respiratory Distress Syndrome. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-13. PMID:31311916. |
real-time pcr and western blot analysis were performed to detect the expression levels of cxcl5, cxcr2, matrix metalloproteinases 2 (mmp2), and matrix metalloproteinases 9 (mmp9) in lung tissues. |
2020-02-13 |
2023-08-13 |
mouse |
| Mary Sproull, Uma Shankavaram, Kevin Camphause. Comparison of Proteomic Biodosimetry Biomarkers Across Five Different Murine Strains. Radiation research. vol 192. issue 6. 2020-02-10. PMID:31618122. |
the current study seeks to compare the expression levels of five previously established proteomic biodosimetry biomarkers of radiation exposure, i.e., flt3 ligand (fl), matrix metalloproteinase 9 (mmp9), serum amyloid a (saa), pentraxin 3 (ptx3) and fibrinogen (fgb), across multiple murine strains and to test a multivariate dose prediction model based on a single c57bl6 strain against other murine strains. |
2020-02-10 |
2023-08-13 |
mouse |
| Xiao Guo, Chengzhan Zhu, Xiaojun Liu, Yiping Ge, Xianyan Jiang, Wei Zha. Hyperoside protects against heart failure-induced liver fibrosis in rats. Acta histochemica. vol 121. issue 7. 2020-02-06. PMID:31353051. |
further, α-smooth-muscle actin (α-sma), collagen i, profibrotic factor-connective tissue growth factor (ctgf), matrix metalloproteinase-2 (mmp2) and mmp9 levels were down-regulated in hyperoside-treated acf rats. |
2020-02-06 |
2023-08-13 |
rat |
| Yafei Chen, Xin Chen, Xiaojun Ding, Yingwei Wan. Afatinib, an EGFR inhibitor, decreases EMT and tumorigenesis of Huh‑7 cells by regulating the ERK‑VEGF/MMP9 signaling pathway. Molecular medicine reports. vol 20. issue 4. 2020-02-04. PMID:31432165. |
furthermore, the activity of the erk signaling pathway and the expression levels of vascular endothelial growth factor (vegf) and matrix metalloproteinase 9 (mmp9) were decreased following treatment with afatinib in vitro. |
2020-02-04 |
2023-08-13 |
Not clear |
| Xiaohu Nie, Yue Zhou, Xiaobing Li, Jie Xu, Xuyan Pan, Rui Yin, Bin L. Calycosin down-regulates c-Met to suppress development of glioblastomas. Journal of biosciences. vol 44. issue 4. 2020-01-30. PMID:31502574. |
meanwhile a western blot assay showed that c-met together with matrix metalloproteinases-9 (mmp9) and phosphorylation of the serine/threonine kinase akt (p-akt) was significantly down-regulated by calycosin. |
2020-01-30 |
2023-08-13 |
Not clear |
| Tan Li, Xu Zhang, Liang Sang, Xin-Tong Li, Hai-Yang Sun, Jun Yang, Yuan Yua. The interaction effects between TLR4 and MMP9 gene polymorphisms contribute to aortic aneurysm risk in a Chinese Han population. BMC cardiovascular disorders. vol 19. issue 1. 2020-01-29. PMID:30922233. |
a cross-talk between toll-like receptor 4 (tlr4) and matrix metalloproteinase 9 (mmp9) plays a vital role in aortic pathophysiology. |
2020-01-29 |
2023-08-13 |
Not clear |
| Yi-Chen Chen, Shih-Chieh Chang, Yu-Han Huang, Ya-Jane Lee, Chao-Chin Chang, Jiunn-Wang Liao, Wei-Li Hs. Expression and the molecular forms of neutrophil gelatinase-associated lipocalin and matrix metalloproteinase 9 in canine mammary tumours. Veterinary and comparative oncology. vol 17. issue 3. 2020-01-28. PMID:31050171. |
the oncogenic role of ngal is related to its molecular forms, and heterodimer formation with matrix metalloproteinase 9 (mmp9) promotes human breast cancer (hbc) invasion and metastasis. |
2020-01-28 |
2023-08-13 |
human |
| Yu Wang, Danyang Zhao, Xiao Wei, Lin Ma, Jing Sheng, Ping L. PEGylated Polyethylenimine Derivative-Mediated Local Delivery of the shSmad3 Inhibits Intimal Thickening after Vascular Injury. BioMed research international. vol 2019. 2020-01-28. PMID:31467913. |
moreover, peg-et 1:1/shsmad3 polyplex treatment significantly inhibited collagen, matrix metalloproteinase 1 (mmp1), mmp2 and mmp9 expression, and upregulated tissue inhibitor of metalloproteinase 1 (timp1) expression both |
2020-01-28 |
2023-08-13 |
Not clear |
| Jian Jiang, Na Shen, Tianyuan Ci, Zhaohui Tang, Zhen Gu, Gao Li, Xuesi Che. Combretastatin A4 Nanodrug-Induced MMP9 Amplification Boosts Tumor-Selective Release of Doxorubicin Prodrug. Advanced materials (Deerfield Beach, Fla.). vol 31. issue 44. 2020-01-24. PMID:31549774. |
a cooperative strategy that utilizes combretastatin a4 nanodrug (ca4-nps) and matrix metalloproteinase 9 (mmp9)-activated doxorubicin prodrug (mmp9-dox-nps) is developed. |
2020-01-24 |
2023-08-13 |
mouse |
| Li Tao, Yingjie Zhu, Ying Gu, Jian Zheng, Jinkun Yan. ARHGAP25: A negative regulator of colorectal cancer (CRC) metastasis via the Wnt/β-catenin pathway. European journal of pharmacology. vol 858. 2020-01-21. PMID:31228451. |
additionally, expression of matrix metalloproteinases (mmp2, mmp7 and mmp9), emt-associated factors (e-cadherin, zeb1, snail and twist1) and β-catenin (a core part of wnt/β-catenin signaling) was determined. |
2020-01-21 |
2023-08-13 |
Not clear |
| Ke Guo, Guo You Wang, Bao Ting Fan, Manoj Kumar Sah, Peng Yu Qu, Shan Yong Zhan. The effect of vascular endothelial growth factor (VEGF) on mouse condylar articular cartilage cultured in vitro. International journal of clinical and experimental pathology. vol 11. issue 11. 2020-01-21. PMID:31949599. |
the mankin score was used to evaluate changes to the condylar cartilage tissues, and immunohistochemistry was performed to observe the expressions of vegf receptor 2 (vegfr2), matrix metallopeptidase 9 (mmp9), matrix metallopeptidase 13 (mmp13), and tumor necrosis factor-related activation-induced cytokine (trance). |
2020-01-21 |
2023-08-13 |
mouse |
| Jianglong Feng, Wenxiu Yang, Jiarui Wang, Zhenhong Pu, Ying Han, Long Wa. Z-VRPR-FMK can inhibit the growth and invasiveness of diffuse large B-cell lymphoma by depressing NF-κB activation and MMP expression induced by MALT1. International journal of clinical and experimental pathology. vol 12. issue 6. 2020-01-17. PMID:31934017. |
the components of the nf-κb signaling pathways, such as p65, malt1, a20, matrix metalloproteinase 2 (mmp2) and mmp9, were detected using a real-time fluorescent quantitative polymerase chain reaction, immunohistochemical staining, and a western blot analysis. |
2020-01-17 |
2023-08-13 |
mouse |
| Sunaina Sapru, Subhayan Das, Mahitosh Mandal, Ananta K Ghosh, Subhas C Kund. Nonmulberry silk protein sericin blend hydrogels for skin tissue regeneration - in vitro and in vivo. International journal of biological macromolecules. vol 137. 2020-01-15. PMID:31220499. |
the in vitro analysis of the hydrogels showed enhanced adhesion, proliferation, and migration of skin cells with coordinated interaction amongst themselves leading to the synthesis of collagen iv and matrix metalloproteinase (mmp2 and mmp9). |
2020-01-15 |
2023-08-13 |
human |