Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xuwen Luo, Xuqiang Liu, Qianyuan Tao, Cong Yao, Fuqiang Wang, Zhiping Gu, Feilong Li, Xiaolong Yu, Bin Zhang, Hongxian Fan, Min Dai, Tao Ni. Enoxacin inhibits proliferation and invasion of human osteosarcoma cells and reduces bone tumour volume in a murine xenograft model. Oncology letters. vol 20. issue 2. 2020-09-28. PMID:32724382. |
these effects were thought to be mediated by downregulation of bcl-xl, bxl-2, matrix metalloproteinase (mmp)2 and mmp9 expression. |
2020-09-28 |
2023-08-13 |
mouse |
Sha Han, Yequan Wang, Chengyan Ge, Mingtao Gao, Xintong Wang, Feiyu Wang, Lei Sun, Sheng Li, Tingting Dong, Zhen Dang, Wen Cui, Guoan Zhang, Ning Li. Pharmaceutical inhibition of AXL suppresses tumor growth and invasion of esophageal squamous cell carcinoma. Experimental and therapeutic medicine. vol 20. issue 5. 2020-09-28. PMID:32952632. |
the expression levels of matrix metalloproteinase (mmp)2 and mmp9, and the activation of protein kinase b (akt), extracellular signal-regulated kinase (erk) and axl signaling were analyzed using gelatin zymography and western blotting. |
2020-09-28 |
2023-08-13 |
Not clear |
Ning Zhu, Yijia Xiang, Xuyong Zhao, Changhong Cai, Hao Chen, Wenbing Jiang, Yi Wang, Chunlai Zen. Thymoquinone suppresses platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferation, migration and neointimal formation. Journal of cellular and molecular medicine. vol 23. issue 12. 2020-09-22. PMID:31638340. |
molecules including the mitochondria-dependent apoptosis factors, matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), pten/akt and mitogen-activated protein kinases (mapks) were determined by western blot. |
2020-09-22 |
2023-08-13 |
rat |
Yong-Moon Lee, Jin Man Kim, Hyo Jin Lee, In-Ock Seong, Kyung-Hee Ki. Immunohistochemical expression of CD44, matrix metalloproteinase2 and matrix metalloproteinase9 in renal cell carcinomas. Urologic oncology. vol 37. issue 10. 2020-09-15. PMID:31053527. |
the aim of our study was to investigate the clinicopathologic values of the expression of cd44, matrix metalloproteinase (mmp)2, and mmp9 in renal cell carcinoma (rcc). |
2020-09-15 |
2023-08-13 |
Not clear |
Melissa A Powell, Raiford T Black, Terry L Smith, Thomas M Reeves, Linda L Phillip. Matrix Metalloproteinase 9 and Osteopontin Interact to Support Synaptogenesis in the Olfactory Bulb after Mild Traumatic Brain Injury. Journal of neurotrauma. vol 36. issue 10. 2020-09-11. PMID:30444175. |
gelatinases (matrix metalloproteinase [mmp]2, mmp9) and their substrate osteopontin (opn) are candidate mediators of synaptogenesis after central nervous system (cns) insult, including olfactory axon damage. |
2020-09-11 |
2023-08-13 |
mouse |
Shipeng Li, Ligong Bian, Xiyue Fu, Qinglong Ai, Yue Sui, Aidan Zhang, Huiqing Gao, Lianmei Zhong, Di L. Gastrodin pretreatment alleviates rat brain injury caused by cerebral ischemic-reperfusion. Brain research. vol 1712. 2020-09-11. PMID:30742808. |
expression of matrix metalloproteinase 2 (mmp2) and mmp9 in gas groups was markedly decreased when compared with mcao group. |
2020-09-11 |
2023-08-13 |
rat |
Qian Zhang, Haitao Xu, Na Bai, Fei Tan, Huirong Xu, Jie Li. Matrix Metalloproteinase 9 is Regulated by LOX-1 and erk1/2 Pathway in Dental Peri-Implantitis. Current pharmaceutical biotechnology. vol 21. issue 9. 2020-09-11. PMID:32081107. |
matrix metalloproteinase 9 (mmp9) is thought to be involved in the pathogenesis of peri-implantitis. |
2020-09-11 |
2023-08-13 |
Not clear |
Li Li, Qiuhong Li, Lei Wei, Zhongfu Wang, Wei Ma, Fangying Liu, Yanhua Shen, Shanfang Zhang, Xiulian Zhang, Huiping Li, Yechang Qia. Chemokine (C-X-C motif) ligand 14 contributes to lipopolysaccharide-induced fibrogenesis in mouse L929 fibroblasts via modulating PPM1A. Journal of cellular biochemistry. vol 120. issue 8. 2020-08-31. PMID:30920024. |
cell proliferation, the levels of matrix metalloproteinase 2 (mmp2) and mmp9, as well as extracellular matrix (ecm) content were assessed to evaluate the fibrogenesis of l929 cells. |
2020-08-31 |
2023-08-13 |
mouse |
Haidong Wang, Min Gao, Jiangbo Li, Jian Sun, Ran Wu, Deping Han, Jianmei Tan, Juan Wang, Bin Wang, Liping Zhang, Yanjun Don. MMP-9-positive neutrophils are essential for establishing profibrotic microenvironment in the obstructed kidney of UUO mice. Acta physiologica (Oxford, England). vol 227. issue 2. 2020-08-31. PMID:31132220. |
matrix metalloproteinase-9 (mmp9) plays a profibrotic role in renal fibrosis. |
2020-08-31 |
2023-08-13 |
mouse |
WenQian Zhang, Wei Sun, Yuan Qin, CangHao Wu, Liang He, Ting Zhang, Liang Shao, Hao Zhang, Ping Zhan. Knockdown of KDM1A suppresses tumour migration and invasion by epigenetically regulating the TIMP1/MMP9 pathway in papillary thyroid cancer. Journal of cellular and molecular medicine. vol 23. issue 8. 2020-08-31. PMID:31211500. |
kdm1a activated matrix metalloproteinase 9 (mmp9) through epigenetic repression of timp1 expression by demethylating h3k4me2 at the timp1 promoter region. |
2020-08-31 |
2023-08-13 |
Not clear |
Jingli Liu, Linda Yu, Lysandra Castro, Yitang Yan, Maria I Sifre, Carl D Bortner, Darlene Dixo. A nongenomic mechanism for "metalloestrogenic" effects of cadmium in human uterine leiomyoma cells through G protein-coupled estrogen receptor. Archives of toxicology. vol 93. issue 10. 2020-08-28. PMID:31468104. |
cd-activated mapk was dependent on gper/egfr transactivation, through significantly increased phospho-src, matrix metalloproteinase-2 (mmp2) and mmp9, and heparin-binding egf-like growth factor (hb-egf) expression/activation. |
2020-08-28 |
2023-08-13 |
human |
Raquel Tonello, Sang Hoon Lee, Temugin Bert. Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice. The journal of pain. vol 20. issue 5. 2020-08-19. PMID:30471427. |
here, we report that paclitaxel-induced mechanical allodynia is associated with transcriptional increase in matrix metalloproteinase (mmp) 2 and 9 and decrease in metallopeptidase inhibitor 1 (timp1), a strong endogenous mmp9 inhibitor. |
2020-08-19 |
2023-08-13 |
mouse |
Ligang Nan, Tao Qin, Ying Xiao, Weikun Qian, Jie Li, Zheng Wang, Jiguang Ma, Qingyong Ma, Zheng W. Pancreatic Stellate Cells Facilitate Perineural Invasion of Pancreatic Cancer via HGF/c-Met Pathway. Cell transplantation. vol 28. issue 9-10. 2020-08-18. PMID:31161784. |
we found that hgf promotes pc cell migration and invasion by activating the hgf/c-met pathway, and enhances the expression of nerve growth factor (ngf) and matrix metalloproteinase-9 (mmp9) in vitro. |
2020-08-18 |
2023-08-13 |
Not clear |
Xin Song, Nan-He Lin, You-Lin Wang, Bin Chen, Hong-Xiang Wang, Kai H. Comprehensive transcriptome analysis based on RNA sequencing identifies critical genes for lipopolysaccharide-induced epididymitis in a rat model. Asian journal of andrology. vol 21. issue 6. 2020-08-17. PMID:31044753. |
four downregulated genes (collagen type xxviii alpha 1 chain [col28α1], cyclin-dependent kinase-like 1 [cdkl1], phosphoserine phosphatase [psph], and fatty acid desaturase 2 [fads2]) and ten upregulated genes (ccaat/enhancer-binding protein beta [cebpβ], c-x-c motif chemokine receptor 2 [cxcr2], interleukin 11 [il11], c-c motif chemokine ligand 20 [ccl20], nuclear factor-kappa-b inhibitor alpha [nfkbiα], claudin 4 [cldn4], matrix metallopeptidase 9 [mmp9], heat shock 70 kda protein 8 [hspa8], intercellular cell adhesion molecule-1 [icam1], and jun) were successfully confirmed by real-time polymerase chain reaction. |
2020-08-17 |
2023-08-13 |
rat |
Hao Jiang, Qian-Qian Shi, Li-Yuan Ge, Qian-Feng Zhuang, Dong Xue, Hai-Yan Xu, Xiao-Zhou H. Selenoprotein M stimulates the proliferative and metastatic capacities of renal cell carcinoma through activating the PI3K/AKT/mTOR pathway. Cancer medicine. vol 8. issue 10. 2020-08-14. PMID:31274247. |
selm could activate the pi3k/akt/mtor pathway and mediate expressions of matrix metallopeptidase 2 and 9 (mmp2, mmp9). |
2020-08-14 |
2023-08-13 |
human |
Huijie Liu, Aiyi Li, Zhichao Sun, Jingyu Zhang, Hua X. Long non-coding RNA NEAT1 promotes colorectal cancer progression by regulating miR-205-5p/VEGFA axis. Human cell. vol 33. issue 2. 2020-08-10. PMID:32065361. |
vegfa, matrix metalloproteinase (mmp)2, and mmp9 protein and mrna expression were measured by western blotting and rt-qpcr analysis, respectively. |
2020-08-10 |
2023-08-13 |
Not clear |
Jacqueline E Heath, Glen M Scholz, Paul D Veith, Eric C Reynold. IL-36γ regulates mediators of tissue homeostasis in epithelial cells. Cytokine. vol 119. 2020-08-06. PMID:30856602. |
here, we show that il-36γ also regulates the expression of matrix metalloproteinase 9 (mmp9) and neutrophil gelatinase-associated lipocalin (ngal), important mediators of antimicrobial immunity and tissue homeostasis in mucosal epithelia. |
2020-08-06 |
2023-08-13 |
Not clear |
Lixia Hui, Yiwen Nie, Shihua Li, Moujian Guo, Wei Yang, Rui Huang, Junsen Chen, Yingxia Liu, Xuancheng Lu, Zhen Chen, Qingyu Yang, Ying W. Matrix metalloproteinase 9 facilitates Zika virus invasion of the testis by modulating the integrity of the blood-testis barrier. PLoS pathogens. vol 16. issue 4. 2020-08-04. PMID:32302362. |
in this study, we revealed that matrix metalloproteinase 9 (mmp9) was upregulated by zikv infection in cell culture and in a129 mice. |
2020-08-04 |
2023-08-13 |
mouse |
Lingyu Kong, Zhongbing Wu, Yang Zhao, Xin Lu, Huijuan Shi, Shugang Liu, Jing L. Qigesan reduces the motility of esophageal cancer cells via inhibiting Gas6/Axl and NF-κB expression. Bioscience reports. vol 39. issue 6. 2020-08-03. PMID:31110076. |
similarly, observing the signal localization and protein expression of p-phosphoinositide3-kinases (pi3k), p-akt protein kinase b (akt), p-nuclear factor-kappa b (nf-κb), matrix metalloproteinase-2 (mmp2), and matrix metalloproteinase-9 (mmp9). |
2020-08-03 |
2023-08-13 |
Not clear |
Xiaoyu Ren, Hongyang Xu, Robert G Barker, Graham D Lamb, Robyn M Murph. Elevated MMP2 abundance and activity in mdx mice are alleviated by prenatal taurine supplementation. American journal of physiology. Cell physiology. vol 318. issue 6. 2020-08-03. PMID:32208990. |
we hypothesized that matrix metalloproteinase-2 (mmp2) and/or mmp9 play key roles in the degeneration/regeneration phases in mdx mice. |
2020-08-03 |
2023-08-13 |
mouse |