| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Niranjan Awasthi, Amanda J Mikels-Vigdal, Erin Stefanutti, Margaret A Schwarz, Sheena Monahan, Victoria Smith, Roderich E Schwar. Therapeutic efficacy of anti-MMP9 antibody in combination with nab-paclitaxel-based chemotherapy in pre-clinical models of pancreatic cancer. Journal of cellular and molecular medicine. vol 23. issue 6. 2020-07-30. PMID:30941918. |
matrix metalloproteinase 9 (mmp9) is involved in the proteolysis of extracellular proteins and plays a critical role in pancreatic ductal adenocarcinoma (pdac) progression, invasion and metastasis. |
2020-07-30 |
2023-08-13 |
mouse |
| Y Park, S Chen, N Ahmad, T Hayami, S Kapil. Estrogen Selectively Enhances TMJ Disc but Not Knee Meniscus Matrix Loss. Journal of dental research. vol 98. issue 13. 2020-07-24. PMID:31526329. |
here, we developed an ovariectomized mouse model in which systemic e2 concentrations mimicked those in cycling women, and we determined the effect of e2 on the targeted turnover of tmj fibrocartilage matrix via e2-induced matrix metalloproteinases mmp9 and mmp13. |
2020-07-24 |
2023-08-13 |
mouse |
| Chiharu Sogawa, Takanori Eguchi, Yuka Okusha, Kisho Ono, Kazumi Ohyama, Motoharu Iizuka, Ryu Kawasaki, Yusaku Hamada, Masaharu Takigawa, Norio Sogawa, Kuniaki Okamoto, Ken-Ichi Kozak. A Reporter System Evaluates Tumorigenesis, Metastasis, β-catenin/MMP Regulation, and Druggability. Tissue engineering. Part A. vol 25. issue 19-20. 2020-07-22. PMID:30734664. |
the high expression of matrix metalloproteinase 9 (mmp9) is a biomarker as well as a causal factor of cancer invasiveness and metastatic activity. |
2020-07-22 |
2023-08-13 |
Not clear |
| Mark Owyong, Jonathan Chou, Renske Je van den Bijgaart, Niwen Kong, Gizem Efe, Carrie Maynard, Dalit Talmi-Frank, Inna Solomonov, Charlotte Koopman, Elin Hadler-Olsen, Mark Headley, Charlene Lin, Chih-Yang Wang, Irit Sagi, Zena Werb, Vicki Plak. MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy. Life science alliance. vol 2. issue 6. 2020-07-22. PMID:31727800. |
we found that matrix metalloproteinase 9 (mmp9) is an important component of the metastatic niche early in tumorigenesis and promotes circulating tumor cells to colonize the lungs. |
2020-07-22 |
2023-08-13 |
Not clear |
| Qixin Wang, Isaac K Sundar, Dongmei Li, Joseph H Lucas, Thivanka Muthumalage, Samantha R McDonough, Irfan Rahma. E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation. Respiratory research. vol 21. issue 1. 2020-07-21. PMID:32552811. |
interestingly, matrix metalloproteinases (mmps), such as mmp2, mmp8 and mmp9, were altered both at the protein and mrna transcript levels in female and male ko mice, but wt mice exposed to pg alone showed a sex-dependent phenotype. |
2020-07-21 |
2023-08-13 |
mouse |
| Zhenbo Tu, Jie Xiong, Ruijing Xiao, Liang Shao, Xiangyong Yang, Lu Zhou, Wen Yuan, Meng Wang, Qian Yin, Yingjie Wu, Shan Pan, Jun Leng, Daozi Jiang, Chunjiang He, Qiuping Zhan. Loss of miR-146b-5p promotes T cell acute lymphoblastic leukemia migration and invasion via the IL-17A pathway. Journal of cellular biochemistry. vol 120. issue 4. 2020-07-20. PMID:30362152. |
gene set enrichment analysis (gsea) and quantitative polymerase chain reaction (qpcr) analysis indicated that matrix metallopeptidase-9 (mmp9), was a potential downstream effector of il-17a activation, and nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb) signaling was also implicated in this process. |
2020-07-20 |
2023-08-13 |
Not clear |
| Mingxing Kou, Dongchun Guo, Lu Liu, Xiaowen Gao, Guiling Xing, Andong Zha, Baoshun Shao, Yuan Sun, Xiuqin Yang, Xibiao Wang, Shengwei Di, Jiancheng Cai, Buyue Ni. Expression pattern and association analysis of porcine matrix metallopeptidase 9 (MMP9) with diarrhea and performance traits in piglets. Research in veterinary science. vol 129. 2020-07-16. PMID:31931263. |
expression pattern and association analysis of porcine matrix metallopeptidase 9 (mmp9) with diarrhea and performance traits in piglets. |
2020-07-16 |
2023-08-13 |
Not clear |
| Mingxing Kou, Dongchun Guo, Lu Liu, Xiaowen Gao, Guiling Xing, Andong Zha, Baoshun Shao, Yuan Sun, Xiuqin Yang, Xibiao Wang, Shengwei Di, Jiancheng Cai, Buyue Ni. Expression pattern and association analysis of porcine matrix metallopeptidase 9 (MMP9) with diarrhea and performance traits in piglets. Research in veterinary science. vol 129. 2020-07-16. PMID:31931263. |
matrix metalloproteinase 9 (mmp9) plays critical roles in multiple biological processes, such as reproduction, cell proliferation and differentiation, and host defenses. |
2020-07-16 |
2023-08-13 |
Not clear |
| Yingqi Liu, Haiyan Wei, Jing Tang, Jiaming Yuan, Mingmin Wu, Chenjuan Yao, Kazuo Hosoi, Shali Yu, Xinyuan Zhao, Yu Han, Gang Che. Dysfunction of pulmonary epithelial tight junction induced by silicon dioxide nanoparticles via the ROS/ERK pathway and protein degradation. Chemosphere. vol 255. 2020-07-08. PMID:32387908. |
sinp-induced matrix metalloproteinase 9 (mmp9) protein expression appeared to be involved in occludin proteolytic degradation, in addition to sinp-induced direct occludin protein degradation. |
2020-07-08 |
2023-08-13 |
mouse |
| Jie Guo, Xuemin Zeng, Jie Miao, Chunpeng Liu, Fulan Wei, Dongxu Liu, Zhong Zheng, Kang Ting, Chunling Wang, Yi Li. MiRNA-218 regulates osteoclast differentiation and inflammation response in periodontitis rats through Mmp9. Cellular microbiology. vol 21. issue 4. 2020-07-06. PMID:30444938. |
here, we show that mirna-218 provides protective effect on periodontitis via regulation of matrix metalloproteinase-9 (mmp9). |
2020-07-06 |
2023-08-13 |
human |
| Xiaofan Yuan, Jianhong Wang, Duozi Wang, Shu Yang, Nengwei Yu, Fuqiang Gu. NSE, S100B and MMP9 Expression Following Reperfusion after Carotid Artery Stenting. Current neurovascular research. vol 16. issue 2. 2020-07-06. PMID:30907315. |
previous studies have shown that the neuron-specific- enolase (nse), s100b protein (s100b) and matrix metalloproteinase-9 (mmp9) are specific markers for studying cerebral injury. |
2020-07-06 |
2023-08-13 |
Not clear |
| Liuzhong Wu, Guirong Zhang, Chuanbo Guo, Xiangyu Zhao, Danyang Shen, Ni Yan. MiR-128-3p mediates TNF-α-induced inflammatory responses by regulating Sirt1 expression in bone marrow mesenchymal stem cells. Biochemical and biophysical research communications. vol 521. issue 1. 2020-07-06. PMID:31635801. |
here, we found that tnf-α treatment induced an inflammatory response by increasing the levels of key inflammatory mediators, including il-6, il-1β, matrix metalloproteinase 9 (mmp9) and monocyte chemotactic protein-1 (mcp-1) in bmscs. |
2020-07-06 |
2023-08-13 |
Not clear |
| Denisa Margină, Anca Ungurianu, Carmen Purdel, Dimitris Tsoukalas, Evangelia Sarandi, Maria Thanasoula, Fotios Tekos, Robin Mesnage, Demetrios Kouretas, Aristidis Tsatsaki. Chronic Inflammation in the Context of Everyday Life: Dietary Changes as Mitigating Factors. International journal of environmental research and public health. vol 17. issue 11. 2020-06-29. PMID:32531935. |
this is often accompanied by chronic low-grade inflammation, driven by the activation of various molecular pathways such as stat3 (signal transducer and activator of transcription 3), ikk (iκb kinase), mmp9 (matrix metallopeptidase 9), mapk (mitogen-activated protein kinases), cox2 (cyclooxigenase 2), and nf-kβ (nuclear factor kappa-light-chain-enhancer of activated b cells). |
2020-06-29 |
2023-08-13 |
Not clear |
| Xueying Jia, Li Gong, Gaosheng Huang, Wei Zhan. [Review of correlation between human parvovirus B19 and autoimmune disease etiology]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 36. issue 1. 2020-06-26. PMID:32314727. |
recent studies have confirmed that anti-b19-vp1u-igg antibody is able to increase the activity of cytokines such as interleukin 1 (il-1), tumor necrosis factor α (tnf-α), matrix metalloproteinase-9 (mmp9); pvb19 protein ns 1 and vp1u are capable of inducing the expression of il-6; pvb19 can induce the production of th17 cell-related cytokines, resulting in the decrease of ifn-gamma levels and the increase of il-4 levels in plasma. |
2020-06-26 |
2023-08-13 |
human |
| Nan Wang, Ruizhen Li, Min Xu. Potential regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis. Journal of cellular and molecular medicine. vol 23. issue 2. 2020-06-18. PMID:30370628. |
in vivo experiments showed that il1rap promoted the expression of caspase-3, a key apoptosis enzyme, but inhibited mmp9, which is responsible for degrading the extracellular matrix, suggesting a significant role of il1rap in cell proliferation, migration, and invasion. |
2020-06-18 |
2023-08-13 |
mouse |
| Sachiko Murase, Dan Winkowski, Ji Liu, Patrick O Kanold, Elizabeth M Quinla. Homeostatic regulation of perisynaptic matrix metalloproteinase 9 (MMP9) activity in the amblyopic visual cortex. eLife. vol 8. 2020-06-15. PMID:31868167. |
homeostatic regulation of perisynaptic matrix metalloproteinase 9 (mmp9) activity in the amblyopic visual cortex. |
2020-06-15 |
2023-08-13 |
mouse |
| S Lupinacci, Anna Perri, G Toteda, D Vizza, F Puoci, O I Parisi, F Giordano, D Lofaro, A La Russa, M Bonofiglio, R Bonofigli. Olive leaf extract counteracts epithelial to mesenchymal transition process induced by peritoneal dialysis, through the inhibition of TGFβ1 signaling. Cell biology and toxicology. vol 35. issue 2. 2020-06-08. PMID:29978330. |
as assessed by changes in the expression of epithelial, mesenchymal, and fibrotic cell markers (such as e-cadherin, n-cadherin, α-sma, fibronectin, vimentin), levels of matrix metalloproteinases (mmp2 and mmp9), and cell migration, ole inhibited the tgfβ1-induced emt. |
2020-06-08 |
2023-08-13 |
Not clear |
| Yingjing Wang, Nan Zhou, Peng Li, Han Wu, Qingqing Wang, Xiaodong Gao, Xudong Wang, Jianfei Huan. EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10. Journal of cellular physiology. vol 234. issue 11. 2020-06-03. PMID:31026069. |
a panel of gc cell lines showed reduced proliferation, invasion, and migration capacities after rna-mediated knockdown of epha8, concomitant with downregulation of the proliferation-related proteins (cyclin a, cyclin d1, and cyclin-dependent kinase 4) and the metastasis-related (matrix metalloproteinases mmp2, and mmp9). |
2020-06-03 |
2023-08-13 |
Not clear |
| Stefania Moz, Mariagrazia Lorenzin, Roberta Ramonda, Vittorio Aneloni, Massimo La Raja, Mario Plebani, Daniela Bass. Emerging role of monocytes and their intracellular calcium pattern in spondyloarthritis. Clinica chimica acta; international journal of clinical chemistry. vol 500. 2020-06-02. PMID:31672632. |
an evaluation was made of the mrna expression levels of inflammatory cytokines (tnf-α, il-1β, tgf-β1, s100a8, s100a9) and matrix metalloproteinases (mmp3, mmp8, mmp9) in blood mononuclear cells of spa patients (n = 64) with respect to controls (n = 100). |
2020-06-02 |
2023-08-13 |
Not clear |
| Trine Pagh Ludvigsen, Lisbeth Høier Olsen, Henrik Duelund Pedersen, Berit Østergaard Christoffersen, Lars Jørn Jense. Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs. Clinical science (London, England : 1979). vol 133. issue 24. 2020-06-01. PMID:31830262. |
at the end of the study (20 months), we assessed body weight, fasting plasma biochemistry, passive vessel dimensions, mrna expression (matrix metallopeptidases 2/9 (mmp2, mmp9), tissue inhibitor of metallopeptidase 1 (timp1), transglutaminase 2 (tgm2), rho-kinase 1 (rock1), tgfβ-receptor 2 (tgfbr2), and igf1-receptor (igfr1) genes), and immunofluorescence in pas and tmas. |
2020-06-01 |
2023-08-13 |
Not clear |