| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mi-Jia Wang, Hao Zhang, Jun Li, Hai-Dong Zha. microRNA-98 inhibits the proliferation, invasion, migration and promotes apoptosis of breast cancer cells by binding to HMGA2. Bioscience reports. vol 38. issue 5. 2019-06-24. PMID:30049846. |
the mrna and protein expressions of hmga2, cell proliferation, cells at the s phase, cell migration, invasion, expressions of matrix metalloproteinase (mmp)2 as well as mmp9 were all reduced in response to mir-98 mimics or sirna-hmga2, while a contradictory trend was observed in the mir-98 inhibitors group. |
2019-06-24 |
2023-08-13 |
human |
| Chengjun Li, Xing Zhou, Chang Sun, Xiaozhou Liu, Xin Shi, Sujia W. Isoliquiritigenin inhibits the proliferation, apoptosis and migration of osteosarcoma cells. Oncology reports. vol 41. issue 4. 2019-06-24. PMID:30720124. |
in addition, isl was able to inhibit the migratory capacity of saos‑2 cells by modulating the expression of matrix metalloproteinase (mmp)2 and mmp9. |
2019-06-24 |
2023-08-13 |
Not clear |
| Canguang Jin, Zhikang Chen, Wei Shi, Qi Lia. Tropomodulin 3 promotes liver cancer progression by activating the MAPK/ERK signaling pathway. Oncology reports. vol 41. issue 5. 2019-06-24. PMID:30864730. |
furthermore, mechanistic analysis indicated that tmod3 overexpression activated mitogen‑activated protein kinase (mapk)/extracellular signal‑regulated kinase (erk) signaling and increased the levels of other targets of this pathway, including matrix metalloproteinase (mmp)2, mmp9 and cyclin d1. |
2019-06-24 |
2023-08-13 |
Not clear |
| Sara Barreto, Arlyng González-Vázquez, Andrew R Cameron, Fergal J O'Brien, Dylan J Murra. Identification of stiffness-induced signalling mechanisms in cells from patent and fused sutures associated with craniosynostosis. Scientific reports. vol 7. issue 1. 2019-06-21. PMID:28904366. |
the differences in the mechanoresponse of these cells were further investigated with a pcr array showing stiffness-dependent upregulation of genes mediating growth and bone development (tshz2, igf1), involved in the breakdown of extracellular matrix (mmp9), mediating the activation of inflammation (il1β) and controlling osteogenic differentiation (wif1, bmp6, nox1) in cells from fused sutures. |
2019-06-21 |
2023-08-13 |
Not clear |
| Dengfeng Li, Hong Wang, Ye Ding, Ziwei Zhang, Zhi Zheng, Jiabin Dong, Hyejin Kim, Xiaojing Meng, Qianjun Zhou, Jia Zhou, Lin Fang, Qiang She. Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis. Cancer letters. vol 424. 2019-06-11. PMID:29580806. |
yd0514 also decreased the protein expression of matrix metalloproteinases 2 and 9 (mmp2 and mmp9), focal adhesion kinase (fak), and integrin family members. |
2019-06-11 |
2023-08-13 |
Not clear |
| Tan Li, Bo Jiang, Xuan Li, Hai-Yang Sun, Xin-Tong Li, Jing-Jing Jing, Jun Yan. Serum matrix metalloproteinase-9 is a valuable biomarker for identification of abdominal and thoracic aortic aneurysm: a case-control study. BMC cardiovascular disorders. vol 18. issue 1. 2019-06-10. PMID:30373522. |
matrix metalloproteinase-9 (mmp9) has been reported to play a key role in the pathogenesis of aortic aneurysm. |
2019-06-10 |
2023-08-13 |
Not clear |
| Tan Li, Jing-Jing Jing, Jun Yang, Li-Ping Sun, Yue-Hua Gong, Shi-Jie Xin, Yuan Yua. Serum levels of matrix metalloproteinase 9 and toll-like receptor 4 in acute aortic dissection: a case-control study. BMC cardiovascular disorders. vol 18. issue 1. 2019-06-10. PMID:30497388. |
matrix metalloproteinase 9 (mmp9) and toll-like receptor 4 (tlr4) play important roles in aortic pathophysiology. |
2019-06-10 |
2023-08-13 |
Not clear |
| Rei Mizuno, Kenji Kawada, Yoshiro Itatani, Ryotaro Ogawa, Yoshiyuki Kiyasu, Yoshiharu Saka. The Role of Tumor-Associated Neutrophils in Colorectal Cancer. International journal of molecular sciences. vol 20. issue 3. 2019-06-04. PMID:30691207. |
tans contribute to the tumor invasion and angiogenesis through the production of matrix metalloproteinase-9 (mmp9), vascular endothelial growth factor (vegf), and hepatocyte growth factor (hgf) in the primary and metastatic sites. |
2019-06-04 |
2023-08-13 |
Not clear |
| Sergio Córdova-Rivas, Ixamail Fraire-Soto, Andrea Mercado-Casas Torres, Luis Steven Servín-González, Angelica Judith Granados-López, Yamilé López-Hernández, Claudia Araceli Reyes-Estrada, Rosalinda Gutiérrez-Hernández, Julio Enrique Castañeda-Delgado, Leticia Ramírez-Hernández, José Antonio Varela-Silva, Jesús Adrián Lópe. 5p and 3p Strands of miR-34 Family Members Have Differential Effects in Cell Proliferation, Migration, and Invasion in Cervical Cancer Cells. International journal of molecular sciences. vol 20. issue 3. 2019-06-04. PMID:30696040. |
we found that mir-34a-5p inhibited proliferation, migration, and cell invasion accompanied by matrix metalloproteinase 9 (mmp9) activity and microtubule-associated protein 2 (map2) protein reduction. |
2019-06-04 |
2023-08-13 |
Not clear |
| Hidemi Misawa, Yuta Morisak. [Motor neuron heterogeneity and selective vulnerability in ALS]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 152. issue 2. 2019-05-30. PMID:30101862. |
we identified that osteopontin (opn) can serve as a marker of fr/s motor neurons, whereas matrix metalloproteinase-9 (mmp9) is expressed by ff motor neurons in mice. |
2019-05-30 |
2023-08-13 |
mouse |
| Zhouhui Ren, Tong Yang, Pingping Zhang, Kaitai Liu, Weihong Liu, Ping Wan. SKA2 mediates invasion and metastasis in human breast cancer via EMT. Molecular medicine reports. vol 19. issue 1. 2019-05-28. PMID:30387823. |
functional investigations revealed that ska2 knockdown in breast cancer cells significantly reduced migration and invasion, and resulted in the decreased expression levels of matrix metalloproteinase (mmp)2 and mmp9. |
2019-05-28 |
2023-08-13 |
human |
| Fang Wang, Min Guan, Liting Wei, Hui Ya. IL‑18 promotes the secretion of matrix metalloproteinases in human periodontal ligament fibroblasts by activating NF‑κB signaling. Molecular medicine reports. vol 19. issue 1. 2019-05-28. PMID:30483730. |
the effects of il‑18 on mrna expression and secretion of matrix metalloproteinase (mmp)1, mmp2, mmp3 and mmp9 in hpdlfs were detected by reverse transcription‑quantitative polymerase chain reaction and elisa, respectively. |
2019-05-28 |
2023-08-13 |
human |
| Yumeng Shi, Dehua Zhou, Bingyi Wang, Deren Zhou, Baomin Sh. Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells. International journal of molecular medicine. vol 43. issue 2. 2019-05-20. PMID:30535491. |
in the ppi network, matrix metallopeptidase 9 (mmp9), early growth response 1 (egr1), smad family member 2 (smad2), and ras‑related c3 botulinum substrate 2 (rac2) were key nodes. |
2019-05-20 |
2023-08-13 |
Not clear |
| Fiona Haxho, Sabah Haq, Myron R Szewczu. Biased G protein-coupled receptor agonism mediates Neu1 sialidase and matrix metalloproteinase-9 crosstalk to induce transactivation of insulin receptor signaling. Cellular signalling. vol 43. 2019-05-13. PMID:29277445. |
a unique neuromedin b (nmbr) gpcr-signaling platform controlling mammalian neuraminidase-1 (neu1) and matrix metalloproteinase-9 (mmp9) crosstalk has been reported in the activation of the insulin receptor (ir) through the modification of the ir glycosylation. |
2019-05-13 |
2023-08-13 |
human |
| Yu-Yan Lan, Fang-Hsin Chang, Jen-Hao Tsai, Yao Chan. Epstein-Barr virus Rta promotes invasion of bystander tumor cells through paracrine of matrix metalloproteinase 9. Biochemical and biophysical research communications. vol 503. issue 3. 2019-05-13. PMID:30082032. |
secretion of matrix metalloproteinase 9 (mmp9), an sasp protein, is increased by rta, which requires the c-terminus of rta and rta-induced activation of e2f. |
2019-05-13 |
2023-08-13 |
Not clear |
| Julian Weiler, Marieke Mohr, Kurt S Zänker, Thomas Dittma. Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells. Cell communication and signaling : CCS. vol 16. issue 1. 2019-05-07. PMID:29636110. |
matrix metalloproteinase-9 (mmp9) is involved in the tnf-α-induced fusion of human m13sv1-cre breast epithelial cells and human mda-mb-435-pfdr1 cancer cells. |
2019-05-07 |
2023-08-13 |
human |
| Chenying Zhang, Jason Lim, Hyeran Helen Jeon, Fanxing Xu, Chen Tian, Fang Miao, Alhassan Hameedaldeen, Dana T Grave. FOXO1 deletion in keratinocytes improves diabetic wound healing through MMP9 regulation. Scientific reports. vol 7. issue 1. 2019-05-01. PMID:28874756. |
matrix metalloproteinase 9 (mmp9) contributes to this process and deficiencies in the mmp9 lead to impaired healing. |
2019-05-01 |
2023-08-13 |
Not clear |
| Palani Dinesh, MahaboobKhan Rasoo. Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated osteoclastogenesis. Cytokine. vol 106. 2019-04-29. PMID:29549724. |
moreover, bbr controlled the osteoclast differentiation via inhibition of various bone resorptive enzymes including: cathepsin k, matrix metalloproteinase 9 (mmp9) and tartarate acid phosphatase (trap). |
2019-04-29 |
2023-08-13 |
rat |
| Yanni Lv, Wen Liu, Zhaohui Ruan, Zixuan Xu, Longsheng F. Myosin IIA Regulated Tight Junction in Oxygen Glucose-Deprived Brain Endothelial Cells Via Activation of TLR4/PI3K/Akt/JNK1/2/14-3-3ε/NF-κB/MMP9 Signal Transduction Pathway. Cellular and molecular neurobiology. vol 39. issue 2. 2019-04-29. PMID:30666520. |
nmmhc iia participated in regulating downstream transduction pathway tlr4, phosphatidylinositol 3-kinase (pi3k), akt, jnk1/2, 14-3-3ε, nuclear factor kappa b (nf-кb) and matrix metalloprotein 9 (mmp9). |
2019-04-29 |
2023-08-13 |
mouse |
| Sifan Wu, Qiongdan Zheng, Xiaoxia Xing, Yinying Dong, Yaohui Wang, Yang You, Rongxin Chen, Chao Hu, Jie Chen, Dongmei Gao, Yan Zhao, Zhiming Wang, Tongchun Xue, Zhenggang Ren, Jiefeng Cu. Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation. Journal of experimental & clinical cancer research : CR. vol 37. issue 1. 2019-04-24. PMID:29728125. |
matrix stiffness-upregulated loxl2 promotes fibronectin production, mmp9 and cxcl12 expression and bmdcs recruitment to assist pre-metastatic niche formation. |
2019-04-24 |
2023-08-13 |
Not clear |