| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Song, Yajie Hu, Hongzhe Li, Xing Huang, Huiwen Zheng, Yunguang Hu, Jingjing Wang, Xi Jiang, Jiaqi Li, Zening Yang, Haitao Fan, Lei Guo, Haijing Shi, Zhanlong He, Fengmei Yang, Xi Wang, Shaozhong Dong, Qihan Li, Longding Li. miR-1303 regulates BBB permeability and promotes CNS lesions following CA16 infections by directly targeting MMP9. Emerging microbes & infections. vol 7. issue 1. 2019-01-22. PMID:30228270. |
the results showed that ca16 infection induced increased permeability of the bbb accompanied by upregulation of matrix metalloproteinase 9 (mmp9) expression. |
2019-01-22 |
2023-08-13 |
monkey |
| Xiaoliang Li, Chunlian Wu, Ying Shen, Ke Wang, Li Tang, Mi Zhou, Ming Yang, Tianying Pan, Xinghui Liu, Wenming X. Ten-eleven translocation 2 demethylates the The Journal of biological chemistry. vol 293. issue 26. 2019-01-17. PMID:29773648. |
both real-time pcr of matrix metalloproteinase (mmp)-related transcripts and a human angiogenesis antibody array indicated that tet2 knockdown in trophoblasts inhibits the expression of mmp transcript, of which mmp9 represented one of the most significant tet2 downstream targets. |
2019-01-17 |
2023-08-13 |
human |
| Anna Mandel, Per Larsson, Martuza Sarwar, Julius Semenas, Azharuddin Sajid Syed Khaja, Jenny L Persso. The interplay between AR, EGF receptor and MMP-9 signaling pathways in invasive prostate cancer. Molecular medicine (Cambridge, Mass.). vol 24. issue 1. 2019-01-17. PMID:30134822. |
in this study, we uncovered the molecular mechanisms underlying the interconnection among the androgen receptor (ar), matrix metalloproteinase-9 (mmp9) and egfr in promoting pca progression. |
2019-01-17 |
2023-08-13 |
Not clear |
| Nagwa A Meguid, Hatem Samir, Geir Bjørklund, Mona Anwar, Adel Hashish, Farouk Koura, Salvatore Chirumbolo, Saher Hashem, Mona A El-Bana, Hebatalla S Hashe. Altered S100 Calcium-Binding Protein B and Matrix Metallopeptidase 9 as Biomarkers of Mesial Temporal Lobe Epilepsy with Hippocampus Sclerosis. Journal of molecular neuroscience : MN. vol 66. issue 4. 2019-01-10. PMID:30343368. |
patients with epilepsy and healthy controls were subjected to a set of laboratory analyses including s100 calcium-binding protein b (s100b), matrix metallopeptidase 9 (mmp9), c-reactive protein (crp), and prolactin (prl), in addition to neurophysiological, radiological, and psychometric assessments, on the basis of the recent evidence of the field. |
2019-01-10 |
2023-08-13 |
Not clear |
| Wei Yan, Shawn Xiang Li, Minjie Wei, Hua Ga. Identification of MMP9 as a novel key gene in mantle cell lymphoma based on bioinformatic analysis and design of cyclic peptides as MMP9 inhibitors based on molecular docking. Oncology reports. vol 40. issue 5. 2018-12-26. PMID:30226602. |
in addition, matrix metalloproteinase 9 (mmp9) with a high degree in the ppi network was identified as a hub gene in mcl. |
2018-12-26 |
2023-08-13 |
Not clear |
| Yi-Tao Duan, Xiao-Ang Yang, Lian-Ying Fang, Jin-Han Wang, Qiang Li. Anti-proliferative and anti-invasive effects of garcinol from Die Pharmazie. vol 73. issue 7. 2018-12-20. PMID:30001777. |
garcinol treatment decreased the activity of matrix metalloproteinase 2 (mmp2) and mmp9 by the downregulation of mrna levels, and these two enzymes are critical to tumor invasion. |
2018-12-20 |
2023-08-13 |
Not clear |
| Zareen Amtul, Jun Yang, Simona Nikolova, Ting-Yim Lee, Robert Bartha, David F Cechett. The Dynamics of Impaired Blood-Brain Barrier Restoration in a Rat Model of Co-morbid Injury. Molecular neurobiology. vol 55. issue 10. 2018-12-18. PMID:29508280. |
within 24 h, cerebral injury resulted in increased bbb permeability due to the dissolution of β-dystroglycan (β-dg) and basement membrane laminin by active matrix metalloproteinase9 (mmp9). |
2018-12-18 |
2023-08-13 |
rat |
| Rita A Costa, Deborah M Powe. Skin and scale regeneration after mechanical damage in a teleost. Molecular immunology. vol 95. 2018-12-11. PMID:29407579. |
the integrity of the integument, as assessed by quantification of extracellular matrix (ecm) gene transcripts (fn1a, coliα1, colvα2, colxα1, ogn1, ogn2, crtac1a, cyr61, pcna, krt2 and mmp9) was restored within 2 days. |
2018-12-11 |
2023-08-13 |
Not clear |
| Nathaniel McGregor, Nicole Thompson, Kevin Sean O'Connell, Robin Emsley, Lize van der Merwe, Louise Warnic. Modification of the association between antipsychotic treatment response and childhood adversity by MMP9 gene variants in a first-episode schizophrenia cohort. Psychiatry research. vol 262. 2018-12-11. PMID:29448178. |
this study investigated the role of variants in matrix metallopeptidase 9 (mmp9), a gene involved in synaptic plasticity, with treatment outcome considering the severity of childhood trauma as an interacting variable. |
2018-12-11 |
2023-08-13 |
Not clear |
| Raphael M Singh, Frank C Howarth, Ernest Adeghate, Keshore Bidasee, Jaipaul Singh, Tehreem Waqa. Type 1 diabetes mellitus induces structural changes and molecular remodelling in the rat kidney. Molecular and cellular biochemistry. vol 449. issue 1-2. 2018-12-11. PMID:29476359. |
these structural changes were associated with elevated extracellular matrix (ecm) deposition and consequently, altered gene expression profile of ecm key components, together with elevated levels of key mediators (mmp9, integrin 5α, timp4, ctgf, vimentin) and reduced expressions of cx43 and mmp2 of the ecm. |
2018-12-11 |
2023-08-13 |
rat |
| Hwa Sun Kim, Andrew Vargas, Yun Sung Eom, Justin Li, Kyra L Yamamoto, Cheryl Mae Craft, Eun-Jin Le. Tissue inhibitor of metalloproteinases 1 enhances rod survival in the rd1 mouse retina. PloS one. vol 13. issue 5. 2018-12-11. PMID:29742163. |
previously, when tissue inhibitor of metalloproteinase 1 (timp1), a key extracellular matrix (ecm) regulator that binds to and inhibits activation of matrix metallopeptidase 9 (mmp9) was intravitreal injected into eyes of a transgenic rhodopsin rat model of rp, s334ter-line3, we discovered cone outer segments are partially protected. |
2018-12-11 |
2023-08-13 |
mouse |
| Hwan-Jin Hwang, Joo Won Kim, Hye Soo Chung, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yo. Knockdown of Sestrin2 Increases Lipopolysaccharide-Induced Oxidative Stress, Apoptosis, and Fibrotic Reactions in H9c2 Cells and Heart Tissues of Mice via an AMPK-Dependent Mechanism. Mediators of inflammation. vol 2018. 2018-12-11. PMID:30116150. |
lps-mediated cell death and the expression of matrix metalloproteinase (mmp) 2 and mmp9 were significantly increased by sesn2 knockdown. |
2018-12-11 |
2023-08-13 |
mouse |
| A Roshini, Srikanth Jagadeesan, Lakshmi Arivazhagan, Young-Jae Cho, Jong-Hwan Lim, Yang-Hoi Doh, Sang-Jae Kim, Jinhee Na, Kyung Hyun Cho. pH-sensitive tangeretin-ZnO quantum dots exert apoptotic and anti-metastatic effects in metastatic lung cancer cell line. Materials science & engineering. C, Materials for biological applications. vol 92. 2018-12-11. PMID:30184773. |
matrix metalloproteinase (mmp)2 and mmp9, markers of metastasis, as well as vascular endothelial growth factor (vegf), a marker of angiogenesis, were significantly downregulated upon treatment with tan-zno qds. |
2018-12-11 |
2023-08-13 |
human |
| Ninggao Dai, Ruifan Ye, Qikuan He, Pengyi Guo, Hao Chen, Qiyu Zhan. Capsaicin and sorafenib combination treatment exerts synergistic anti‑hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling. Oncology reports. vol 40. issue 6. 2018-12-11. PMID:30272354. |
the combination of capsaicin and sorafenib also inhibited cell invasion and metastasis via upregulation of e‑cadherin and downregulation of n‑cadherin, vimentin, matrix metalloproteinase (mmp)2 and mmp9. |
2018-12-11 |
2023-08-13 |
Not clear |
| Zhi-Li Xu, Yi Zhang, Ling Wang, Feng Li, Hong-Wei Man, Peng-Fei Li, Bao-En Sha. B7‑H3 promotes malignant progression of muscle‑invasive bladder cancer. Oncology reports. vol 40. issue 5. 2018-11-27. PMID:30132557. |
the protein expression of ki67, proliferating cell nuclear antigen (pcna), matrix metalloproteinase 2 (mmp2) and mmp9 were decreased in the t24/b7‑h3 shrna group compared with the control (p<0.05, respectively). |
2018-11-27 |
2023-08-13 |
mouse |
| Xin Wang, Mengjie Gu, Tan Boon Toh, Nurrul Lissa Binti Abdullah, Edward Kai-Hua Cho. Stimuli-Responsive Nanodiamond-Based Biosensor for Enhanced Metastatic Tumor Site Detection. SLAS technology. vol 23. issue 1. 2018-11-26. PMID:29020497. |
in this study, we investigated the use of nanodiamonds to develop a stimuli-responsive metastasis detection complex that utilizes matrix metalloproteinase 9 (mmp9) as a metastasis biomarker, as mmp9 increased expression has been shown to be indicative of metastasis. |
2018-11-26 |
2023-08-13 |
Not clear |
| Jinkyung Kim, Sung-Min Kang, Su Young Oh, Soo Hyun Kang, Inhan Lee, Jae Chan Hwang, Heon-Jin Lee, So-Young Choi, Su-Hyung Hon. Early Growth Response 1-Dependent Downregulation of Matrix Metalloproteinase 9 and Mouse Double Minute 2 Attenuates Head and Neck Squamous Cell Carcinoma Metastasis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 50. issue 5. 2018-11-26. PMID:30396177. |
there is no previous data showing the effect of egr1 on mouse double minute 2 (mdm2), an enhancer of matrix metalloproteinase 9 (mmp9) expression. |
2018-11-26 |
2023-08-13 |
mouse |
| Andrey V Barkhash, Andrey A Yurchenko, Nikolay S Yudin, Elena V Ignatieva, Irina V Kozlova, Inessa A Borishchuk, Larisa L Pozdnyakova, Mikhail I Voevoda, Aida G Romaschenk. A matrix metalloproteinase 9 (MMP9) gene single nucleotide polymorphism is associated with predisposition to tick-borne encephalitis virus-induced severe central nervous system disease. Ticks and tick-borne diseases. vol 9. issue 4. 2018-11-21. PMID:29496490. |
a matrix metalloproteinase 9 (mmp9) gene single nucleotide polymorphism is associated with predisposition to tick-borne encephalitis virus-induced severe central nervous system disease. |
2018-11-21 |
2023-08-13 |
human |
| Andrey V Barkhash, Andrey A Yurchenko, Nikolay S Yudin, Elena V Ignatieva, Irina V Kozlova, Inessa A Borishchuk, Larisa L Pozdnyakova, Mikhail I Voevoda, Aida G Romaschenk. A matrix metalloproteinase 9 (MMP9) gene single nucleotide polymorphism is associated with predisposition to tick-borne encephalitis virus-induced severe central nervous system disease. Ticks and tick-borne diseases. vol 9. issue 4. 2018-11-21. PMID:29496490. |
one of these snps is rs6558394 (g/a, pro422leu) in the scribbled planar cell polarity protein (scrib) gene and the other snp is rs17576 (a/g, gln279arg) in the matrix metalloproteinase 9 (mmp9) gene. |
2018-11-21 |
2023-08-13 |
human |
| Shu Li, Hongying Dai, Yong He, Shusheng Peng, Tianjin Zhu, Yang Wu, Chenwei Li, Ke Wan. BMP9 inhibits the growth of breast cancer cells by downregulation of the PI3K/Akt signaling pathway. Oncology reports. vol 40. issue 3. 2018-11-15. PMID:30015950. |
the expression levels of cyclins d1, b1 and e1, c‑myc and matrix metalloproteinase 9 (mmp9) in the mda‑mb‑231/bmp9 group were also reduced. |
2018-11-15 |
2023-08-13 |
mouse |