| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiang Su, Changqing Gao, Rong Wang, Cangsong Xiao, Ming Yan. Genes associated with inflammation and the cell cycle may serve as biomarkers for the diagnosis and prognosis of acute myocardial infarction in a Chinese population. Molecular medicine reports. vol 18. issue 2. 2018-10-19. PMID:29845217. |
the upregulated degs were predicted to participate in inflammatory pathways, including the toll‑like receptor (tlr) signaling pathway, including ras‑related c3 botulinum toxin substrate 1 (rac1), tlr4, c‑c motif chemokine receptor (ccr)1; cytokine‑cytokine receptor interaction, including signal transducer and activator of transcription (stat)3; chemokine signaling pathway, including ccr10; pathways associated with cancer, including colony stimulating factor 3 receptor (csf3r); and leukocyte transendothelial migration, including matrix metallopeptidase 9 (mmp9). |
2018-10-19 |
2023-08-13 |
Not clear |
| Julian K Christians, Kendra I Lennie, Maria F Huicochea Munoz, Nimrat Binnin. PAPP-A2 deficiency does not exacerbate the phenotype of a mouse model of intrauterine growth restriction. Reproductive biology and endocrinology : RB&E. vol 16. issue 1. 2018-10-16. PMID:29895300. |
we predicted that, if the upregulation of papp-a2 in pregnancy complications reflects a compensatory response, then deletion of pappa2 in mice would exacerbate the effects of a gene deletion previously reported to impair placental development: deficiency of matrix metalloproteinase-9 (mmp9). |
2018-10-16 |
2023-08-13 |
mouse |
| Xiang Chen, Chaowen Shi, Cong Wang, Weilin Liu, Yanhong Chu, Zou Xiang, Kebin Hu, Ping Dong, Xiaodong Ha. The role of miR-497-5p in myofibroblast differentiation of LR-MSCs and pulmonary fibrogenesis. Scientific reports. vol 7. 2018-10-15. PMID:28098218. |
in addition, as determined by luciferase assays and western blot analysis, reversion-inducing cysteine-rich protein with kazal motifs (reck) was identified to be one of the target genes of mir-497-5p, and reck could suppress the expression of matrix metalloproteinase-2 (mmp2) and mmp9, which could activate latent transforming growth factor-β1 (tgf-β1). |
2018-10-15 |
2023-08-13 |
Not clear |
| Shuping Yang, Yange Zhang, Yi Luo, Bocheng Xu, Yuqin Yao, Yuanle Deng, Fangfang Yang, Tinghong Ye, Gang Wang, Zhiqiang Cheng, Yu Zheng, Yongmei Xi. Hinokiflavone induces apoptosis in melanoma cells through the ROS-mitochondrial apoptotic pathway and impairs cell migration and invasion. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-10-15. PMID:29635122. |
furthermore, hinokiflavone effectively impaired a375 cells migration and invasion, and down-regulated the expression of matrix metalloproteinase (mmp) mmp2 and mmp9. |
2018-10-15 |
2023-08-13 |
human |
| Yan Qin, Qianqian Zhai, Yan Li, Meng Cao, Yun Xu, Kelei Zhao, Tao Wan. Cyanidin-3-O-glucoside ameliorates diabetic nephropathy through regulation of glutathione pool. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-10-15. PMID:29864902. |
c3g also reduced the ratio of kidney to body weight and the levels of blood urea nitrogen (bun), serum creatinine, urinary albumin content and albumin/creatinine ratio (acr), ameliorated the pathological changes of kidneys, reduced the surface area of bowman's capsule, glomerular tuft, bowman's space, and decreased renal expression of collagen iv, fibronectin, transforming growth factor β 1 (tgfβ1), matrix metalloprotein 9 (mmp9) and α-smooth muscle actin (α-sma) in db/db mice. |
2018-10-15 |
2023-08-13 |
mouse |
| H Murawala, S Patel, I Ranadive, I Desai, S Balakrishna. Variation in expression and activity pattern of mmp2 and mmp9 on different time scales in the regenerating caudal fin of Poecilia latipinna. Journal of fish biology. vol 92. issue 5. 2018-10-02. PMID:29633266. |
alteration in the expression pattern of matrix metalloproteinase (mmp)2 and mmp9 was studied in the regenerating caudal fin of poecilia latipinna immediately following amputation until the new tissues gained structural integrity. |
2018-10-02 |
2023-08-13 |
Not clear |
| H Murawala, S Patel, I Ranadive, I Desai, S Balakrishna. Variation in expression and activity pattern of mmp2 and mmp9 on different time scales in the regenerating caudal fin of Poecilia latipinna. Journal of fish biology. vol 92. issue 5. 2018-10-02. PMID:29633266. |
based on the results, it could be construed that the controlled up-regulation of mmp2 and mmp9 from 1 hpa until the early differentiation stage ensures a regulated digestion of extracellular matrix, perhaps to facilitate the recruitment, proliferation, morphogenesis and re-patterning of resident stem cells during caudal fin regeneration in p. latipinna. |
2018-10-02 |
2023-08-13 |
Not clear |
| Huijiang Zhou, Jiangfeng Xu, Shuai Wang, Jinfeng Pen. Role of cantharidin in the activation of IKKα/IκBα/NF‑κB pathway by inhibiting PP2A activity in cholangiocarcinoma cell lines. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29620225. |
the expression levels of 72 kda type iv collagenase (mmp2) and matrix metalloproteinase 9 (mmp9) were downregulated by can. |
2018-09-26 |
2023-08-13 |
human |
| Ai-Lei Wang, Yong Li, Qun Zhao, Li-Qiao Fa. Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29620230. |
further studies revealed that treatment with form inhibits matrix metalloproteinase (mmp)2 and mmp9 expression. |
2018-09-26 |
2023-08-13 |
Not clear |
| Xue-Feng Zhang, Xue-Qi Zhang, Zhe-Xing Chang, Cui-Cui Wu, Hang Gu. microRNA‑145 modulates migration and invasion of bladder cancer cells by targeting N‑cadherin. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693148. |
subsequently, expression of n‑cadherin and matrix metalloproteinase‑9 (mmp9) in bc cells were detected by western blot analysis. |
2018-09-26 |
2023-08-13 |
Not clear |
| Hangbin Jin, Yanyan Zhao, Shirong Zhang, Jianfeng Yang, Xiaofeng Zhang, Shenglin M. Hyperthermia inhibits the motility of gemcitabine-resistant pancreatic cancer PANC-1 cells through the inhibition of epithelial-mesenchymal transition. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568909. |
additionally, emt in pan/gem cells was reversed by hyperthermia, as demonstrated by the restoration of e‑cadherin and downregulation of mesenchymal markers vimentin, matrix metalloproteinase (mmp)2 and mmp9. |
2018-09-21 |
2023-08-13 |
Not clear |
| Jie Zhu, Jun Ren, Liming Tan. Genistein inhibits invasion and migration of colon cancer cells by recovering WIF1 expression. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568950. |
following treatment with genistein, matrix metalloproteinase (mmp) 2 and mmp9 expression levels decreased, whereas the expression of metalloproteinase inhibitor 1 and e‑cadherin increased significantly. |
2018-09-21 |
2023-08-13 |
Not clear |
| Rui Yang, Li Han, Xiantie Zen. A functional polymorphism at miR‑491‑5p binding site in the 3'UTR of MMP9 gene confers increased risk for pressure ulcers after hip fracture. Oncology reports. vol 39. issue 6. 2018-09-21. PMID:29620239. |
the roles of matrix metalloproteinase (mmp)9 in the control of pressure ulcers (pu) after hip fracture as well as how the rs1056629 in mmp9 3'utr compromises the interaction between mmp9 and mir‑491 were explored. |
2018-09-21 |
2023-08-13 |
human |
| Shi-Jie Zhan, Bin Liu, Hua Lingh. Identifying genes as potential prognostic indicators in patients with serous ovarian cancer resistant to carboplatin using integrated bioinformatics analysis. Oncology reports. vol 39. issue 6. 2018-09-20. PMID:29693178. |
through survival analysis, comparison of genes across numerous analyses, and immunohistochemistry, gnai1, non‑structural maintenance of chromosomes (non‑smc) condensin i complex subunit h (ncaph), matrix metallopeptidase 9 (mmp9), aurora kinase a (aurka) and enhancer of zeste 2 polycomb repressive complex 2 subunit (ezh2) were identified as the key molecules that may be involved in the carcinogenesis and carboplatin resistance of soc. |
2018-09-20 |
2023-08-13 |
Not clear |
| Seok Hee Lee, Erif M N Setyawan, Yoo Bin Choi, Jeong Chan Ra, Sung Keun Kang, Byeong Chun Lee, Geon A Ki. Clinical assessment after human adipose stem cell transplantation into dogs. Journal of veterinary science. vol 19. issue 3. 2018-09-18. PMID:29284215. |
elisa results for angiogenic and anti-inflammatory factors including matrix metalloproteinase 9 (mmp9), vascular endothelial growth factor (vegf), basic fibroblast growth factor (bfgf), hepatocyte growth factor (hgf), and interleukin-10 (il-10) were significantly higher in the two ascs groups than in the controls. |
2018-09-18 |
2023-08-13 |
human |
| X Zhang, X Rong, Y Chen, L S. Methylation-mediated loss of SFRP2 enhances invasiveness of non-small cell lung cancer cells. Human & experimental toxicology. vol 37. issue 2. 2018-09-18. PMID:29320940. |
furthermore, the demethylation of sfrp2 gene appeared to inhibit zinc finger e-box binding homeobox 1 (zeb1) and matrix metallopeptidase 9 (mmp9), two key factors that enhance nsclc cell invasion. |
2018-09-18 |
2023-08-13 |
Not clear |
| Brandon Alexander Holt, Quoc D Mac, Gabriel A Kwon. Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics. Journal of visualized experiments : JoVE. issue 137. 2018-09-13. PMID:30059042. |
herein we describe construction of a nanosensor for matrix metalloproteinase 9 (mmp9), which is associated with tumor progression and metastasis, for detection of colorectal cancer in a mouse model. |
2018-09-13 |
2023-08-13 |
mouse |
| Nobutaka Ogasawara, Tamami Kudo, Masaki Sato, Yasushi Kawasaki, Sei Yonezawa, Satoru Takahashi, Yohei Miyagi, Yasuhiro Natori, Akinori Sugiyam. Reduction of Membrane Protein CRIM1 Decreases E-Cadherin and Increases Claudin-1 and MMPs, Enhancing the Migration and Invasion of Renal Carcinoma Cells. Biological & pharmaceutical bulletin. vol 41. issue 4. 2018-09-11. PMID:29607933. |
in addition, increased expression of matrix metalloproteinase (mmp) 2 and mmp9, protease essential for cancer cell invasiveness, was observed. |
2018-09-11 |
2023-08-13 |
Not clear |
| Qianqian Wang, Haiou Xu, Xiaofeng Zha. Baicalin Inhibits Human Cervical Cancer Cells by Suppressing Protein Kinase C/Signal Transducer and Activator of Transcription (PKC/STAT3) Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-09-10. PMID:29610452. |
the expression levels of pkcζ, survivin, matrix metalloproteinase (mmp)2, mmp9 as well as the phosphorylation of signal transducer and activator of transcription (stat) 3 were reduced in baicalin administrated cervical cancer cells. |
2018-09-10 |
2023-08-13 |
human |
| Lei Zhang, Changtian Wang, Zhilong Xi, Demin Li, Zhiyun X. Mercaptoethanol Protects the Aorta from Dissection by Inhibiting Oxidative Stress, Inflammation, and Extracellular Matrix Degeneration in a Mouse Model. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-09-06. PMID:29589594. |
material and methods twenty-four 8-month-old c57bl/6j mice were divided into three groups and studied for two weeks: 1) the aortic dissection (ad) model group (n=8) underwent intraperitoneal injection of angiotensin ii (ang ii) (5 ml/kg) three times every 24 h; 2) the mercaptoethanol treated group (n=8) were given oral mercaptoethanol (2.5 mm); the normal group (n=8) underwent intraperitoneal injection of noradrenaline (5 mg/kg) three times every 24 h. sections of mouse aorta were prepared for histology with hematoxylin and eosin (h&e) staining; immunohistochemistry was performed to detect levels of: nuclear factor (erythroid-derived 2)-like 2 (nfe2l2), nuclear factor κb (nf-κb), p65, superoxide dismutase-1 (sod1), glutamate cysteine ligase catalytic subunit (gclc), tumor necrosis factor α (tnf-α), interleukin-1β (il-1β), and matrix metalloproteinase-9 (mmp9). |
2018-09-06 |
2023-08-13 |
mouse |