| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Li, Junjie Xie, Chuan Shen, Dongfeng Cheng, Yuan Shi, Zhichong Wu, Qian Zhan, Xiaxing Deng, Hao Chen, Baiyong Shen, Chenghong Peng, Hongwei Li, Zhecheng Zh. miR-150-5p inhibits hepatoma cell migration and invasion by targeting MMP14. PloS one. vol 9. issue 12. 2016-01-08. PMID:25549355. |
the matrix metalloproteinase 14 (mmp14) is identified as a new target gene of mir-150-5p. |
2016-01-08 |
2023-08-13 |
Not clear |
| Adrian Fischer, Tilman Brummer, Bettina Warscheid, Gerald Radziwil. Differential tyrosine phosphorylation controls the function of CNK1 as a molecular switch in signal transduction. Biochimica et biophysica acta. vol 1853. issue 11 Pt A. 2015-12-16. PMID:26319181. |
contrary, mutants preventing tyrosine phosphorylation promote matrix metalloproteinase mmp14 promoter activity. |
2015-12-16 |
2023-08-13 |
Not clear |
| Ting-hua Yan, Zhong-hao Lin, Jin-hua Jiang, Sui-wan Lu, Hua-xing Que, Miao-an Chen, Xiang-sheng He, Gan-bo Que, Ji-nan Xiao, Yuan-qing Che. Matrix Metalloproteinase 14 Overexpression Is Correlated with the Progression and Poor Prognosis of Nasopharyngeal Carcinoma. Archives of medical research. vol 46. issue 3. 2015-10-30. PMID:25829357. |
matrix metalloproteinase 14 (mmp14) has been identified to play a significant role in several types of cancers, but little is known about the significance of mmp14 in nasopharyngeal carcinoma (npc) patients. |
2015-10-30 |
2023-08-13 |
Not clear |
| Tao Li, Junjie Xie, Chuan Shen, Dongfeng Cheng, Yuan Shi, Zhichong Wu, Xiaxing Deng, Hao Chen, Baiyong Shen, Chenghong Peng, Hongwei Li, Qian Zhan, Zhecheng Zh. Amplification of Long Noncoding RNA ZFAS1 Promotes Metastasis in Hepatocellular Carcinoma. Cancer research. vol 75. issue 15. 2015-10-26. PMID:26069248. |
mir-150 repressed hcc cell invasion by inhibiting zeb1 and the matrix metalloproteinases mmp14 and mmp16. |
2015-10-26 |
2023-08-13 |
Not clear |
| Ana Gutiérrez-Fernández, Clara Soria-Valles, Fernando G Osorio, Jesús Gutiérrez-Abril, Cecilia Garabaya, Alina Aguirre, Antonio Fueyo, María Soledad Fernández-García, Xose S Puente, Carlos López-Otí. Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid. The EMBO journal. vol 34. issue 14. 2015-10-02. PMID:25991604. |
mt1-mmp (mmp14) is a collagenolytic enzyme located at the cell surface and implicated in extracellular matrix (ecm) remodeling. |
2015-10-02 |
2023-08-13 |
mouse |
| Ilya Ulasov, Anton V Borovjagin, Natalya Kaverina, Brett Schroeder, Nameeta Shah, Biaoyang Lin, Anatoly Baryshnikov, Charles Cobb. MT1-MMP silencing by an shRNA-armed glioma-targeted conditionally replicative adenovirus (CRAd) improves its anti-glioma efficacy in vitro and in vivo. Cancer letters. vol 365. issue 2. 2015-10-01. PMID:26052095. |
mmp14 (mt1-mmp) is a cell membrane-associated proteinase of the extracellular matrix, whose biological roles vary from angiogenesis to cell proliferation and survival. |
2015-10-01 |
2023-08-13 |
Not clear |
| Y V Loskutov, P Y Kozyulina, V K Kozyreva, R J Ice, B C Jones, T J Roston, M B Smolkin, A V Ivanov, R B Wysolmerski, E N Pugachev. NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer. Oncogene. vol 34. issue 28. 2015-09-29. PMID:25241893. |
in the current study, we have found that nedd9 is required for matrix metalloproteinase 14 (mmp14) enzymatic recovery/recycling through the late endosomes to enable disengagement of tissue inhibitor of matrix metalloproteinase 2 (timp2) and tumor invasion. |
2015-09-29 |
2023-08-13 |
Not clear |
| Jianfeng Zhang, Xiujiang Sun, Jing Liu, Jianqing Liu, Binghua Shen, Lin Ni. The role of matrix metalloproteinase 14 polymorphisms in susceptibility to intervertebral disc degeneration in the Chinese Han population. Archives of medical science : AMS. vol 11. issue 4. 2015-08-31. PMID:26322093. |
matrix metalloproteinase 14 (mmp14) plays an important role in the pathophysiology of intervertebral disc degeneration (ivdd). |
2015-08-31 |
2023-08-13 |
Not clear |
| Nguyen D Thang, Ichiro Yajima, Shoko Ohnuma, Nobutaka Ohgami, Mayuko Y Kumasaka, Gaku Ichihara, Masashi Kat. Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time. Environmental toxicology. vol 30. issue 2. 2015-07-27. PMID:23804419. |
constitutive invasion activity, focal adhesion kinase (fak) protein expression and activity, and matrix metalloproteinase 14 (mmp14) protein expression in primary cultured normal human epidermal keratinocytes, hacat keratinocytes, and hsc5 and a431 human squamous cell carcinoma cells were augmented following an increase in malignancy grade of the cells. |
2015-07-27 |
2023-08-12 |
human |
| Li Zeng, Bowen Tan, Yalan Yang, Jinyi Qiu, Lili Xiong, Canquan Ma. [Virtual screening and molecular simulations of antisense peptides targeting MT1-MMP]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 31. issue 2. 2015-07-17. PMID:26062348. |
membrane type-1 matrix metalloproteinase (mt1-mmp or mmp14) plays the pivotal role in tumor development and metastasis, so it is a promising drug target in malignancy. |
2015-07-17 |
2023-08-13 |
Not clear |
| Tinghua Yan, Zhonghao Lin, Jinhua Jiang, Suiwan Lu, Miaoan Chen, Huaxing Que, Xiangsheng He, Ganbo Que, Jianfeng Mao, Jinan Xiao, Qingwei Zhen. MMP14 regulates cell migration and invasion through epithelial-mesenchymal transition in nasopharyngeal carcinoma. American journal of translational research. vol 7. issue 5. 2015-07-15. PMID:26175856. |
matrix metalloproteinase 14 (mmp14) has been shown to play a significant role in several types of cancers, but little is known about the function of mmp14 in nasopharyngeal carcinoma (npc) carcinogenesis. |
2015-07-15 |
2023-08-13 |
Not clear |
| Yichen Dong, Guohua Chen, Mingming Gao, Xia Tia. Increased expression of MMP14 correlates with the poor prognosis of Chinese patients with gastric cancer. Gene. vol 563. issue 1. 2015-06-25. PMID:25748728. |
the role of matrix metalloproteinase 14 (mmp14) has been identified to involve tumor progression and prognosis. |
2015-06-25 |
2023-08-13 |
Not clear |
| Iain R Macpherson, Elena Rainero, Louise E Mitchell, Peter V E van den Berghe, Claire Speirs, Marta A Dozynkiewicz, Suman Chaudhary, Gabriela Kalna, Joanne Edwards, Paul Timpson, Jim C Norma. CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer. Journal of cell science. vol 127. issue Pt 18. 2015-06-22. PMID:25015290. |
here, we show that in two estrogen receptor (er)-negative breast cancer cell lines, clic3 has little influence on integrin recycling, but controls trafficking of the pro-invasive matrix metalloproteinase mt1-mmp (also known as mmp14). |
2015-06-22 |
2023-08-13 |
Not clear |
| Aaron C Overland, Paul A Inse. Heterotrimeric G proteins directly regulate MMP14/membrane type-1 matrix metalloprotease: a novel mechanism for GPCR-EGFR transactivation. The Journal of biological chemistry. vol 290. issue 16. 2015-06-19. PMID:25759388. |
we have tested the hypothesis that transactivation can occur by a membrane-delimited process: direct increase in the activity of membrane type-1 matrix metalloprotease (mmp14, mt1-mmp) by heterotrimeric g proteins, and in turn, the generation of heparin-binding epidermal growth factor (hb-egf) and activation of egfr. |
2015-06-19 |
2023-08-13 |
rat |
| Dajiang Wu, Kai Chen, Yushu Bai, Xiaodong Zhu, Ziqiang Chen, Chuanfeng Wang, Yingchuan Zhao, Ming L. Screening of diagnostic markers for osteosarcoma. Molecular medicine reports. vol 10. issue 5. 2015-06-09. PMID:25199469. |
from the results, it was observed that col1a2 and col5a2 interact with a number of genes of the matrix metalloprotease (mmp) family, including mmp1, mmp2, mmp3 and mmp14, tgfβ and runx2. |
2015-06-09 |
2023-08-13 |
Not clear |
| Pernilla von Nandelstadh, Erika Gucciardo, Jouko Lohi, Rui Li, Nami Sugiyama, Olli Carpen, Kaisa Leht. Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton. Molecular biology of the cell. vol 25. issue 17. 2015-05-28. PMID:24989798. |
during this process, cancer cells undergo cytoskeletal reorganization and up-regulate membrane-type 1 matrix metalloproteinase (mt1-mmp; mmp14), which functions in actin-based pseudopods to drive invasion by extracellular matrix degradation. |
2015-05-28 |
2023-08-13 |
human |
| F C Brownfoot, N Hannan, K Onda, S Tong, T Kaitu'u-Lin. Soluble endoglin production is upregulated by oxysterols but not quenched by pravastatin in primary placental and endothelial cells. Placenta. vol 35. issue 9. 2015-05-13. PMID:25043692. |
recently oxysterols, which activate the liver x receptor (lxr), have been implicated in producing seng, by upregulating matrix metalloproteinase-14 (mmp14; cleaves endoglin to produce seng) and down-regulating tissue inhibitor of metalloproteinase-3 (timp-3; inhibitor of mmp14). |
2015-05-13 |
2023-08-13 |
human |
| Gaetano Terrone, Gerarda Cappuccio, Rita Genesio, Annalisa Esposito, Valeria Fiorentino, Marina Riccitelli, Lucio Nitsch, Nicola Brunetti-Pierri, Ennio Del Giudic. A case of 14q11.2 microdeletion with autistic features, severe obesity and facial dysmorphisms suggestive of Wolf-Hirschhorn syndrome. American journal of medical genetics. Part A. vol 164A. issue 1. 2015-04-13. PMID:24243641. |
the most interesting genes included in this deletion are chd8, a chromodomain helicase dna binding protein that is associated with autism spectrum disorders, and mmp14, a matrix metalloproteinase that has been linked to obesity and type 2 diabetes. |
2015-04-13 |
2023-08-12 |
Not clear |
| Huayang Wang, Huanhuan Cheng, Qianqian Shao, Zhaogang Dong, Qi Xie, Lei Zhao, Qingjie Wang, Beihua Kong, Xun Q. Leptin-promoted human extravillous trophoblast invasion is MMP14 dependent and requires the cross talk between Notch1 and PI3K/Akt signaling. Biology of reproduction. vol 90. issue 4. 2014-11-21. PMID:24571988. |
mmp14 is a member of matrix metalloproteinase (mmp) family that is closely involved in the invasion process. |
2014-11-21 |
2023-08-12 |
human |
| Sarah L McLaughlin, Ryan J Ice, Anuradha Rajulapati, Polina Y Kozyulina, Ryan H Livengood, Varvara K Kozyreva, Yuriy V Loskutov, Mark V Culp, Scott A Weed, Alexey V Ivanov, Elena N Pugachev. NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis. Molecular cancer research : MCR. vol 12. issue 1. 2014-10-01. PMID:24202705. |
depletion of nedd9 impaired invasion of cancer cells through inactivation of membrane-bound matrix metalloproteinase mmp14 by excess timp2 on the cell surface. |
2014-10-01 |
2023-08-12 |
Not clear |