| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ghodratolah Naseh, Mahyar Mohammadifard, Mahtab Mohammadifar. Upregulation of cyclin-dependent kinase 7 and matrix metalloproteinase-14 expression contribute to metastatic properties of gastric cancer. IUBMB life. vol 68. issue 10. 2017-08-11. PMID:27562173. |
the aim of this study was to evaluate the protein and mrna expressions of matrix metalloproteinase-14 (mmp14) and cdk7 in gastric cancer (gc) tissues. |
2017-08-11 |
2023-08-13 |
Not clear |
| Kirtiman Srivastava, Adam Pickard, Simon McDade, Dennis J McCanc. p63 drives invasion in keratinocytes expressing HPV16 E6/E7 genes through regulation of Src-FAK signalling. Oncotarget. vol 8. issue 10. 2017-07-07. PMID:26001294. |
in addition, specific inhibition of fak (pf573228) or src (dasatinib) activities mitigated invasion and attenuated the expression/activity of matrix metalloproteinase 14 (mmp14), a pivotal mmp in the mmp activation cascade. |
2017-07-07 |
2023-08-13 |
human |
| Kirtiman Srivastava, Adam Pickard, Simon McDade, Dennis J McCanc. p63 drives invasion in keratinocytes expressing HPV16 E6/E7 genes through regulation of Src-FAK signalling. Oncotarget. vol 8. issue 10. 2017-07-07. PMID:26001294. |
depletion of src, fak or akt in the invasive cells normalised the expression/activity of c-jun and mmp14, thus implicating the src-fak/akt/ap-1 signalling in mmp14-mediated extra-cellular matrix remodelling. |
2017-07-07 |
2023-08-13 |
human |
| Kyu-Yeon Han, Jin-Hong Chang, Hyun Lee, Dimitri T Aza. Proangiogenic Interactions of Vascular Endothelial MMP14 With VEGF Receptor 1 in VEGFA-Mediated Corneal Angiogenesis. Investigative ophthalmology & visual science. vol 57. issue 7. 2017-06-12. PMID:27327585. |
matrix metalloproteinase 14 (mmp14) has been shown to be required for corneal angiogenesis. |
2017-06-12 |
2023-08-13 |
Not clear |
| Marcin Stawowczyk, Max D Wellenstein, Sharrell B Lee, Shira Yomtoubian, Anna Durrans, Hyejin Choi, Navneet Narula, Nasser K Altorki, Dingcheng Gao, Vivek Mitta. Matrix Metalloproteinase 14 promotes lung cancer by cleavage of Heparin-Binding EGF-like Growth Factor. Neoplasia (New York, N.Y.). vol 19. issue 2. 2017-05-04. PMID:28013056. |
matrix metalloproteinase 14 (mmp14), a membrane-bound proteinase, was significantly up-regulated in the tumor epithelial cells and intratumoral myeloid compartments in both mouse and human nsclc. |
2017-05-04 |
2023-08-13 |
mouse |
| Marcin Stawowczyk, Max D Wellenstein, Sharrell B Lee, Shira Yomtoubian, Anna Durrans, Hyejin Choi, Navneet Narula, Nasser K Altorki, Dingcheng Gao, Vivek Mitta. Matrix Metalloproteinase 14 promotes lung cancer by cleavage of Heparin-Binding EGF-like Growth Factor. Neoplasia (New York, N.Y.). vol 19. issue 2. 2017-05-04. PMID:28013056. |
overexpression of a soluble dominant negative mmp14 (dn-mmp14) or pharmacological inhibition of mmp14 blocked invasion of lung cancer cells through a collagen i matrix in vitro and reduced tumor incidence in an orthotopic k-ras |
2017-05-04 |
2023-08-13 |
mouse |
| Mariana Sponchiado, Nathália Souza Gomes, Patrícia Kubo Fontes, Thiago Martins, Maite Del Collado, Athos de Assumpção Pastore, Guilherme Pugliesi, Marcelo Fábio Gouveia Nogueira, Mario Binell. Pre-hatching embryo-dependent and -independent programming of endometrial function in cattle. PloS one. vol 12. issue 4. 2017-04-28. PMID:28423001. |
regulation included downregulation of genes associated with proliferation (igf1, igf2, igf1r and igf2r) and extracellular matrix remodeling (mmp14, mmp19 and mmp2) and upregulation of anti-adhesive genes (muc1) in the cranial regions of uterine horn. |
2017-04-28 |
2023-08-13 |
cattle |
| Kyu-Yeon Han, Jin-Hong Chang, Dimitri T Aza. MMP14 Regulates VEGFR3 Expression on Corneal Epithelial Cells. Protein and peptide letters. vol 23. issue 12. 2017-03-27. PMID:27781955. |
to determine whether matrix metalloproteinase 14 (mmp14) modulates vegfr3 expression in the corneal epithelium to influence the avascularity of the cornea, vegfr3 expression was compared between wild-type and mmp14-deficient (mmp14 Δexon4) corneal epithelial cells. |
2017-03-27 |
2023-08-13 |
Not clear |
| Yijun Yang, Yi Jiang, Yicong Wan, Lin Zhang, Jiangnan Qiu, Shulin Zhou, Wenjun Chen. UCA1 functions as a competing endogenous RNA to suppress epithelial ovarian cancer metastasis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26867765. |
depletion of uca1 was involved in the downregulation of matrix metallopeptidase 14 (mmp14) expression, a target gene of mir-485-5p. |
2017-02-21 |
2023-08-13 |
Not clear |
| Pu Zhao, Yilin Xu, Yong Wei, Qiong Qiu, Teng-Leong Chew, Yibin Kang, Chonghui Chen. The CD44s splice isoform is a central mediator for invadopodia activity. Journal of cell science. vol 129. issue 7. 2016-12-30. PMID:26869223. |
our results suggest that cd44s promotes cortactin phosphorylation and recruits mt1-mmp (also known as mmp14) to sites of matrix degradation, which are important activities for invadopodia function. |
2016-12-30 |
2023-08-13 |
Not clear |
| M Ebisawa, H Iwano, M Nishikawa, Y Tochigi, T Komatsu, Y Endou, K Hirayama, H Taniyama, T Kadosawa, H Yokot. Significance of caveolin-1 and matrix metalloproteinase 14 gene expression in canine mammary tumours. Veterinary journal (London, England : 1997). vol 206. issue 2. 2016-12-13. PMID:26364240. |
the aim of this study was to examine whether caveolin-1 (cav-1) and matrix metalloproteinase 14 (mmp14) are associated with cmt histological malignancy and invasion. |
2016-12-13 |
2023-08-13 |
Not clear |
| Jui M Dave, Colette A Abbey, Camille L Duran, Heewon Seo, Gregory A Johnson, Kayla J Bayles. Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. Journal of cell science. vol 129. issue 4. 2016-12-13. PMID:26769900. |
pro-angiogenic factors enhanced colocalization and complex formation between membrane type-1 matrix metalloproteinase (mt1-mmp, also known as mmp14) and hic-5, but not between paxillin and mt1-mmp. |
2016-12-13 |
2023-08-13 |
Not clear |
| Ying-Hui Zhang, Juan-Juan Wang, Min Li, Han-Xi Zheng, Lan Xu, You-Guo Che. Matrix Metallopeptidase 14 Plays an Important Role in Regulating Tumorigenic Gene Expression and Invasion Ability of HeLa Cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 26. issue 3. 2016-12-13. PMID:26825836. |
the objectives of this study were to investigate the functional effect of matrix metallopeptidase 14 (mmp14) on cell invasion in cervical cancer cells (hela line) and to study the underlying molecular mechanisms. |
2016-12-13 |
2023-08-13 |
Not clear |
| Nikita G Alexiades, Brenda Auffinger, Chung Kwon Kim, Tanwir Hasan, Gina Lee, Marc Deheeger, Alex L Tobias, Janice Kim, Irina Balyasnikova, Maciej S Lesniak, Karen Aboody, Atique U Ahme. MMP14 as a novel downstream target of VEGFR2 in migratory glioma-tropic neural stem cells. Stem cell research. vol 15. issue 3. 2016-11-09. PMID:26513555. |
we identified vascular endothelial growth factor-a (vegfa) and membrane-bound matrix metalloproteinase (mmp14) as molecules whose expression are significantly elevated in migratory nscs. |
2016-11-09 |
2023-08-13 |
Not clear |
| Kotaro Horiguchi, Ken Fujiwara, Takehiro Tsukada, Hideji Yako, Kozue Tateno, Rumi Hasegawa, Shu Takigami, Shunji Ohsako, Takashi Yashiro, Takako Kato, Yukio Kat. Expression of Slug in S100β-protein-positive cells of postnatal developing rat anterior pituitary gland. Cell and tissue research. vol 363. issue 2. 2016-10-24. PMID:26246400. |
to analyze downstream of slug in s100β-positive cells, we utilized specific small interfering rna for slug mrnas and observed that the expression of matrix metalloprotease (mmp) 9, mmp14 and chemokine cxcl12 was down-regulated and that morphological changes and proliferation were decreased. |
2016-10-24 |
2023-08-13 |
rat |
| Ayse Bakir, Philippa D Darbr. Effect of aluminium on migration of oestrogen unresponsive MDA-MB-231 human breast cancer cells in culture. Journal of inorganic biochemistry. vol 152. 2016-10-11. PMID:26365320. |
in parallel, al exposure was found to give rise to increased secretion of active matrix metalloproteinase mmp9 as measured by zymography, and increased intracellular levels of activated mmp14 as measured by western immunoblotting. |
2016-10-11 |
2023-08-13 |
human |
| Jessica A Kendziorski, Scott M Belche. Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A. Reproductive toxicology (Elmsford, N.Y.). vol 58. 2016-09-26. PMID:26307436. |
increased collagen i and iii expression, decreased matrix metalloproteinase 2 (mmp2) and mmp14 expression, and increased immune response were associated with the endometrosis phenotype in the c57bl/6n strain and the 30ppm bpa cd-1 group. |
2016-09-26 |
2023-08-13 |
mouse |
| Q-F Zuo, L-Y Cao, T Yu, L Gong, L-N Wang, Y-L Zhao, B Xiao, Q-M Zo. MicroRNA-22 inhibits tumor growth and metastasis in gastric cancer by directly targeting MMP14 and Snail. Cell death & disease. vol 6. 2016-09-14. PMID:26610210. |
we further demonstrated that mir-22 acted as tumor suppressors through targeting extracellular matrix (ecm) remodeling member matrix metalloproteinase 14 (mmp14) and epithelial-to-mesenchymal transition (emt) inducer snail in gc. |
2016-09-14 |
2023-08-13 |
human |
| Selma Maacha, Océane Anezo, Malika Foy, Géraldine Liot, Laurence Mery, Cécile Laurent, Xavier Sastre-Garau, Sophie Piperno-Neumann, Nathalie Cassoux, Nathalie Planque, Simon Saul. Protein Tyrosine Phosphatase 4A3 (PTP4A3) Promotes Human Uveal Melanoma Aggressiveness Through Membrane Accumulation of Matrix Metalloproteinase 14 (MMP14). Investigative ophthalmology & visual science. vol 57. issue 4. 2016-09-02. PMID:27096756. |
protein tyrosine phosphatase 4a3 (ptp4a3) promotes human uveal melanoma aggressiveness through membrane accumulation of matrix metalloproteinase 14 (mmp14). |
2016-09-02 |
2023-08-13 |
human |
| Si Qin, Fengming Wang, Meng Zhou, Wen'ge Ding, Lujun Chen, Yahua L. Immunolocalization of membrane-type 1 MMP in human rheumatoid synovium tissues. International journal of clinical and experimental pathology. vol 8. issue 8. 2016-08-03. PMID:26464678. |
membrane-type 1 matrix metalloproteinase (mt1-mmp, also known as mmp14), the best characterized membrane-anchored mmp, is an important matrix-degrading proteinase that could digest a broad spectrum of extracellular matrix proteins and accelerate angiogenesis. |
2016-08-03 |
2023-08-13 |
human |