| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marcin Stawowczyk, Max D Wellenstein, Sharrell B Lee, Shira Yomtoubian, Anna Durrans, Hyejin Choi, Navneet Narula, Nasser K Altorki, Dingcheng Gao, Vivek Mitta. Matrix Metalloproteinase 14 promotes lung cancer by cleavage of Heparin-Binding EGF-like Growth Factor. Neoplasia (New York, N.Y.). vol 19. issue 2. 2017-05-04. PMID:28013056. |
overexpression of a soluble dominant negative mmp14 (dn-mmp14) or pharmacological inhibition of mmp14 blocked invasion of lung cancer cells through a collagen i matrix in vitro and reduced tumor incidence in an orthotopic k-ras |
2017-05-04 |
2023-08-13 |
mouse |
| Mariana Sponchiado, Nathália Souza Gomes, Patrícia Kubo Fontes, Thiago Martins, Maite Del Collado, Athos de Assumpção Pastore, Guilherme Pugliesi, Marcelo Fábio Gouveia Nogueira, Mario Binell. Pre-hatching embryo-dependent and -independent programming of endometrial function in cattle. PloS one. vol 12. issue 4. 2017-04-28. PMID:28423001. |
regulation included downregulation of genes associated with proliferation (igf1, igf2, igf1r and igf2r) and extracellular matrix remodeling (mmp14, mmp19 and mmp2) and upregulation of anti-adhesive genes (muc1) in the cranial regions of uterine horn. |
2017-04-28 |
2023-08-13 |
cattle |
| Kyu-Yeon Han, Jin-Hong Chang, Dimitri T Aza. MMP14 Regulates VEGFR3 Expression on Corneal Epithelial Cells. Protein and peptide letters. vol 23. issue 12. 2017-03-27. PMID:27781955. |
to determine whether matrix metalloproteinase 14 (mmp14) modulates vegfr3 expression in the corneal epithelium to influence the avascularity of the cornea, vegfr3 expression was compared between wild-type and mmp14-deficient (mmp14 Δexon4) corneal epithelial cells. |
2017-03-27 |
2023-08-13 |
Not clear |
| Yijun Yang, Yi Jiang, Yicong Wan, Lin Zhang, Jiangnan Qiu, Shulin Zhou, Wenjun Chen. UCA1 functions as a competing endogenous RNA to suppress epithelial ovarian cancer metastasis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26867765. |
depletion of uca1 was involved in the downregulation of matrix metallopeptidase 14 (mmp14) expression, a target gene of mir-485-5p. |
2017-02-21 |
2023-08-13 |
Not clear |
| Pu Zhao, Yilin Xu, Yong Wei, Qiong Qiu, Teng-Leong Chew, Yibin Kang, Chonghui Chen. The CD44s splice isoform is a central mediator for invadopodia activity. Journal of cell science. vol 129. issue 7. 2016-12-30. PMID:26869223. |
our results suggest that cd44s promotes cortactin phosphorylation and recruits mt1-mmp (also known as mmp14) to sites of matrix degradation, which are important activities for invadopodia function. |
2016-12-30 |
2023-08-13 |
Not clear |
| M Ebisawa, H Iwano, M Nishikawa, Y Tochigi, T Komatsu, Y Endou, K Hirayama, H Taniyama, T Kadosawa, H Yokot. Significance of caveolin-1 and matrix metalloproteinase 14 gene expression in canine mammary tumours. Veterinary journal (London, England : 1997). vol 206. issue 2. 2016-12-13. PMID:26364240. |
the aim of this study was to examine whether caveolin-1 (cav-1) and matrix metalloproteinase 14 (mmp14) are associated with cmt histological malignancy and invasion. |
2016-12-13 |
2023-08-13 |
Not clear |
| Jui M Dave, Colette A Abbey, Camille L Duran, Heewon Seo, Gregory A Johnson, Kayla J Bayles. Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. Journal of cell science. vol 129. issue 4. 2016-12-13. PMID:26769900. |
pro-angiogenic factors enhanced colocalization and complex formation between membrane type-1 matrix metalloproteinase (mt1-mmp, also known as mmp14) and hic-5, but not between paxillin and mt1-mmp. |
2016-12-13 |
2023-08-13 |
Not clear |
| Ying-Hui Zhang, Juan-Juan Wang, Min Li, Han-Xi Zheng, Lan Xu, You-Guo Che. Matrix Metallopeptidase 14 Plays an Important Role in Regulating Tumorigenic Gene Expression and Invasion Ability of HeLa Cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 26. issue 3. 2016-12-13. PMID:26825836. |
the objectives of this study were to investigate the functional effect of matrix metallopeptidase 14 (mmp14) on cell invasion in cervical cancer cells (hela line) and to study the underlying molecular mechanisms. |
2016-12-13 |
2023-08-13 |
Not clear |
| Nikita G Alexiades, Brenda Auffinger, Chung Kwon Kim, Tanwir Hasan, Gina Lee, Marc Deheeger, Alex L Tobias, Janice Kim, Irina Balyasnikova, Maciej S Lesniak, Karen Aboody, Atique U Ahme. MMP14 as a novel downstream target of VEGFR2 in migratory glioma-tropic neural stem cells. Stem cell research. vol 15. issue 3. 2016-11-09. PMID:26513555. |
we identified vascular endothelial growth factor-a (vegfa) and membrane-bound matrix metalloproteinase (mmp14) as molecules whose expression are significantly elevated in migratory nscs. |
2016-11-09 |
2023-08-13 |
Not clear |
| Kotaro Horiguchi, Ken Fujiwara, Takehiro Tsukada, Hideji Yako, Kozue Tateno, Rumi Hasegawa, Shu Takigami, Shunji Ohsako, Takashi Yashiro, Takako Kato, Yukio Kat. Expression of Slug in S100β-protein-positive cells of postnatal developing rat anterior pituitary gland. Cell and tissue research. vol 363. issue 2. 2016-10-24. PMID:26246400. |
to analyze downstream of slug in s100β-positive cells, we utilized specific small interfering rna for slug mrnas and observed that the expression of matrix metalloprotease (mmp) 9, mmp14 and chemokine cxcl12 was down-regulated and that morphological changes and proliferation were decreased. |
2016-10-24 |
2023-08-13 |
rat |
| Ayse Bakir, Philippa D Darbr. Effect of aluminium on migration of oestrogen unresponsive MDA-MB-231 human breast cancer cells in culture. Journal of inorganic biochemistry. vol 152. 2016-10-11. PMID:26365320. |
in parallel, al exposure was found to give rise to increased secretion of active matrix metalloproteinase mmp9 as measured by zymography, and increased intracellular levels of activated mmp14 as measured by western immunoblotting. |
2016-10-11 |
2023-08-13 |
human |
| Jessica A Kendziorski, Scott M Belche. Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A. Reproductive toxicology (Elmsford, N.Y.). vol 58. 2016-09-26. PMID:26307436. |
increased collagen i and iii expression, decreased matrix metalloproteinase 2 (mmp2) and mmp14 expression, and increased immune response were associated with the endometrosis phenotype in the c57bl/6n strain and the 30ppm bpa cd-1 group. |
2016-09-26 |
2023-08-13 |
mouse |
| Q-F Zuo, L-Y Cao, T Yu, L Gong, L-N Wang, Y-L Zhao, B Xiao, Q-M Zo. MicroRNA-22 inhibits tumor growth and metastasis in gastric cancer by directly targeting MMP14 and Snail. Cell death & disease. vol 6. 2016-09-14. PMID:26610210. |
we further demonstrated that mir-22 acted as tumor suppressors through targeting extracellular matrix (ecm) remodeling member matrix metalloproteinase 14 (mmp14) and epithelial-to-mesenchymal transition (emt) inducer snail in gc. |
2016-09-14 |
2023-08-13 |
human |
| Selma Maacha, Océane Anezo, Malika Foy, Géraldine Liot, Laurence Mery, Cécile Laurent, Xavier Sastre-Garau, Sophie Piperno-Neumann, Nathalie Cassoux, Nathalie Planque, Simon Saul. Protein Tyrosine Phosphatase 4A3 (PTP4A3) Promotes Human Uveal Melanoma Aggressiveness Through Membrane Accumulation of Matrix Metalloproteinase 14 (MMP14). Investigative ophthalmology & visual science. vol 57. issue 4. 2016-09-02. PMID:27096756. |
protein tyrosine phosphatase 4a3 (ptp4a3) promotes human uveal melanoma aggressiveness through membrane accumulation of matrix metalloproteinase 14 (mmp14). |
2016-09-02 |
2023-08-13 |
human |
| Si Qin, Fengming Wang, Meng Zhou, Wen'ge Ding, Lujun Chen, Yahua L. Immunolocalization of membrane-type 1 MMP in human rheumatoid synovium tissues. International journal of clinical and experimental pathology. vol 8. issue 8. 2016-08-03. PMID:26464678. |
membrane-type 1 matrix metalloproteinase (mt1-mmp, also known as mmp14), the best characterized membrane-anchored mmp, is an important matrix-degrading proteinase that could digest a broad spectrum of extracellular matrix proteins and accelerate angiogenesis. |
2016-08-03 |
2023-08-13 |
human |
| Hidetoshi Mori, Ramray Bhat, Alexandre Bruni-Cardoso, Emily I Chen, Danielle M Jorgens, Kester Coutinho, Katherine Louie, Benjamin Ben Bowen, Jamie L Inman, Victoria Tecca, Sarah J Lee, Sabine Becker-Weimann, Trent Northen, Motoharu Seiki, Alexander D Borowsky, Manfred Auer, Mina J Bissel. New insight into the role of MMP14 in metabolic balance. PeerJ. vol 4. 2016-08-01. PMID:27478693. |
membrane-anchored matrix metalloproteinase 14 (mmp14) is involved broadly in organ development through both its proteolytic and signal-transducing functions. |
2016-08-01 |
2023-08-13 |
mouse |
| Xiaohui Zhang, Min Feng, Xin Liu, Li Bai, Ming Kong, Yu Chen, Sujun Zheng, Shuang Liu, Yu-Jui Yvonne Wan, Zhongping Duan, Yuan-Ping Ha. Persistence of cirrhosis is maintained by intrahepatic regulatory T cells that inhibit fibrosis resolution by regulating the balance of tissue inhibitors of metalloproteinases and matrix metalloproteinases. Translational research : the journal of laboratory and clinical medicine. vol 169. 2016-07-12. PMID:26613891. |
as a consequence of tregs depletion, the expression of matrix metalloproteinases (mmps) and tissue inhibitors of metalloproteinases (timps) was altered; mmp9 and timp1 were reduced, whereas mmp2 and mmp14 were enhanced. |
2016-07-12 |
2023-08-13 |
mouse |
| Fares Zeidán-Chuliá, Mervi Gürsoy, Ben-Hur Neves de Oliveira, Vural Özdemir, Eija Könönen, Ulvi K Gürso. A Systems Biology Approach to Reveal Putative Host-Derived Biomarkers of Periodontitis by Network Topology Characterization of MMP-REDOX/NO and Apoptosis Integrated Pathways. Frontiers in cellular and infection microbiology. vol 5. 2016-06-14. PMID:26793622. |
we found ubiquitin c (ubc), jun proto-oncogene (jun), and matrix metalloproteinase-14 (mmp14) as the most central hub- and non-hub-bottlenecks among the 211 genes/proteins of the whole interactome. |
2016-06-14 |
2023-08-13 |
Not clear |
| Bi-Sen Ding, Kazunori Gomi, Shahin Rafii, Ronald G Crystal, Matthew S Walter. Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells. Journal of cell science. vol 128. issue 16. 2016-05-31. PMID:26116571. |
stimulation of endothelial cells with basal-cell-derived growth factors induced endothelial cell expression of matrix metallopeptidase 14 (mmp14), and short hairpin rna (shrna)-mediated knockdown of endothelial cell mmp14 significantly reduced the endothelial-cell-dependent growth of basal cells. |
2016-05-31 |
2023-08-13 |
human |
| Muraly Puttabyatappa, Terry A Jacot, Linah F Al-Alem, Katherine L Rosewell, Diane M Duffy, Mats Brännström, Thomas E Curr. Ovarian membrane-type matrix metalloproteinases: induction of MMP14 and MMP16 during the periovulatory period in the rat, macaque, and human. Biology of reproduction. vol 91. issue 2. 2016-05-09. PMID:24920038. |
ovarian membrane-type matrix metalloproteinases: induction of mmp14 and mmp16 during the periovulatory period in the rat, macaque, and human. |
2016-05-09 |
2023-08-13 |
human |