| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephan Niland, Johannes A Ebl. Decoding the MMP14 Integrin Link: Key Player in the Secretome Landscape. Matrix biology : journal of the International Society for Matrix Biology. 2025-01-19. PMID:39828138. |
among the many molecules of the secretome, integrins and matrix metalloproteinase 14 (mmp14) stand out as the interplay of adhesion and proteolysis drives invasion. |
2025-01-19 |
2025-01-23 |
Not clear |
| Stephan Niland, Johannes A Ebl. Decoding the MMP14 Integrin Link: Key Player in the Secretome Landscape. Matrix biology : journal of the International Society for Matrix Biology. 2025-01-19. PMID:39828138. |
integrins serve as mechanosensors that mediate the contact of cells with the scaffold of the extracellular matrix and are significantly involved in the precise positioning and activity control of the membrane-bound collagenase mmp14. |
2025-01-19 |
2025-01-23 |
Not clear |
| Mariano Colon-Caraballo, Serena R Russell, Kristin M Myers, Mala Mahendro. Collagen turnover during cervical remodeling involves both intracellular and extracellular collagen degradation pathways. Biology of reproduction. 2025-01-17. PMID:39823285. |
extracellular collagen degradation is achieved by the activity of fibroblast-derived matrix metalloproteases mmp14, mmp2, and fibroblast activation protein (fap). |
2025-01-17 |
2025-01-20 |
mouse |
| Jiaxu Zhao, Rui Zeng, Xiaohui Li, Ying Lu, Zuoyun Wang, Haibao Peng, Hao Chen, Minjie Fu, Ye Zhang, Yang Huang, Wenhan Chen, Xin Wang, Yun Guan, Wei Han, Ruofan Huang, Chengjun Yao, Zhiyong Qin, Lingchao Chen, Liang Chen, Xue Feng, Hanting Yang, Patrícia M R Pereira, Xuemei Tong, Bin Li, Qiangqiang Zhang, Yudan Ch. Dura immunity configures leptomeningeal metastasis immunosuppression for cerebrospinal fluid barrier invasion. Nature cancer. vol 5. issue 12. 2024-12-22. PMID:39710801. |
mechanically, we find that dura-derived lm-associated macrophages (dlams) migrate into the csf in a matrix metalloproteinase 14 (mmp14)-dependent manner. |
2024-12-22 |
2024-12-25 |
mouse |
| Shannon C Kelly, Cassandra B Higgins, Jiameng Sun, Joshua A Adams, Yiming Zhang, Samuel Ballentine, Yong Miao, XiaoXia Cui, Małgorzata Milewska, Ilona Wandzik, Jun Yoshino, Benjamin M Swarts, Shun-Ichi Wada, Brian J DeBosc. Hepatocyte MMP14 mediates liver and inter-organ inflammatory responses to diet-induced liver injury. PNAS nexus. vol 3. issue 9. 2024-09-16. PMID:39282008. |
the matrix metalloproteinase mmp14 is a ubiquitously expressed, membrane-bound, secreted endopeptidase that proteolyzes substrates to regulate development, signaling, and metabolism. |
2024-09-16 |
2024-09-19 |
Not clear |
| Sei Muraoka, William D Brodie, Megan N Mattichak, Mikel Gurrea-Rubio, Yuzo Ikari, Caroline Foster, M Asif Amin, Neha Khanna, Hafsa Amin, Phillip L Campbell, Sirapa Vichaikul, Ellen N Model, Morgan M Omara, Steven Petrovski, Karly Kozicki, Camilia Amarista, Anna Webber, Mustafa Ali, Pamela J Palisoc, Jonatan Hervoso, Jeffrey H Ruth, Lam C Tsoi, John Varga, Johann E Gudjonsson, Dinesh Khanna, David A Fox, Pei-Suen Tso. Targeting CD13/aminopeptidase N as a novel therapeutic approach for scleroderma fibrosis. Arthritis & rheumatology (Hoboken, N.J.). 2024-08-23. PMID:39175116. |
soluble cd13 (scd13), generated by cleavage of cell surface cd13 via matrix metalloproteinase 14 (mmp14), signals through the bradykinin receptor b1 (b1r) to elicit pro-inflammatory, pro-arthritic, and pro-angiogenic responses. |
2024-08-23 |
2024-08-25 |
Not clear |
| Yanan Zhang, Yufen Liu, Yanyan Shi, Chunyu Bai, Ting Wang, Fang Ruan, Chuanbing H. Upregulation of MMPs in placentas of patients with gestational diabetes mellitus: Involvement of the PI3K/Akt pathway. Heliyon. vol 10. issue 12. 2024-07-18. PMID:39021921. |
subsequent analysis indicated that the expression levels of matrix metalloproteinases (mmp) 11, mmp12, mmp14, and mmp15, which are regulated by the pi3k/akt pathway, were upregulated in the placentas of patients with gdm when compared to those of individuals with normal placental function. |
2024-07-18 |
2024-07-20 |
Not clear |
| Xiaoyan Li, Jian Zhao, Lei Chen, Xinyi Zhou, Minglong Qiu, Lianfu Deng, Kai Yang, Yaozeng X. HIF-1α activation impairs dendrites formation and elongation in osteocytogenesis. Heliyon. vol 10. issue 12. 2024-07-16. PMID:39005918. |
this process is followed by activation of the erm/rhoa pathway and recruitment of matrix metalloproteinase 14 (mmp14) to facilitate extracellular matrix degradation, enabling dendrite elongation. |
2024-07-16 |
2024-07-18 |
Not clear |
| Farideh Sabeh, Xiao-Yan Li, Adam W Olson, Elliot Botvinick, Abhishek Kurup, Luis E Gimenez, Jung-Sun Cho, Stephen J Weis. Mmp14-dependent remodeling of the pericellular-dermal collagen interface governs fibroblast survival. The Journal of cell biology. vol 223. issue 9. 2024-07-11. PMID:38990714. |
coincident with this biosynthetic program, fibroblasts proteolytically remodel pericellular collagen fibrils by mobilizing the membrane-anchored matrix metalloproteinase, mmp14. |
2024-07-11 |
2024-07-14 |
mouse |
| Richa Shrivastava, Puneet Gandhi, Sandeep K Sorte, Adesh Shrivastav. Characterizing the Linkage of Systemic Hypoxia and Angiogenesis in High-Grade Glioma to Define the Changes in Tumor Microenvironment for Predicting Prognosis. Journal of molecular neuroscience : MN. vol 74. issue 3. 2024-07-05. PMID:38967861. |
herein, markers representing four components of the tumor microenvironment (tme) were identified to define their linked expression in tme and predict the prognosis in hgg, namely, interleukin6 (il6, inflammation), inducible nitric oxide synthase(inos), heat shock protein-70 (hsp70, hypoxia), vascular endothelial growth receptor (vegf), and endothelin1 (et1) (angiogenesis) and matrix metalloprotease-14 (mmp14) and intercellular adhesion molecule1 (icam1, extracellular matrix). |
2024-07-05 |
2024-07-11 |
Not clear |
| Luqi Qiu, Haijiao Xu, Binglin Sui, Pengwei Jiang, Jiaqi Wang, Dandan Xu, Feng Liang, Tao Ma, Hongda Wang, Junling Che. Elucidating the Functional Mechanism of PTK7 in Cancer Development through Spatial Assembly Analysis Using Super Resolution Imaging. Analytical chemistry. 2024-05-06. PMID:38708542. |
furthermore, we discovered that the spatial distribution morphology of ptk7 was also subject to the hydrolysis ability and activation state of the related hydrolase matrix metallopeptidase14 (mmp14). |
2024-05-06 |
2024-05-08 |
human |
| Signe Meng, Ester E Sørensen, Muthulakshmi Ponniah, Jeppe Thorlacius-Ussing, Roxane Crouigneau, Tanja Larsen, Magnus T Borre, Nicholas Willumsen, Mette Flinck, Stine F Pederse. MCT4 and CD147 co-localize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells. Journal of cell science. 2024-04-25. PMID:38661040. |
mct4 and cd147 co-localize with mmp14 in invadopodia and support matrix degradation and invasion by breast cancer cells. |
2024-04-25 |
2024-04-28 |
Not clear |
| Dan Peng, Juan Li, Yin Li, Lingling Bai, Anying Xiong, Xiang He, Xiaolan Li, Qin Ran, Lei Zhang, Manling Jiang, Junyi Wang, Elaine Lai-Han Leung, Pingchang Yang, Guoping L. MMP14 Pharmacological research. 2024-01-13. PMID:38218353. |
in this study, a decision tree model showed that matrix metalloproteinase-14 (mmp14) had higher scores for important features in the up-regulated genes in macrophages from mice exposed to the saccharopolyspora rectivirgula antigen (sr-ag). |
2024-01-13 |
2024-01-16 |
mouse |
| Huiping Jin, Quankai Wang, Yiting Gu, Baolier Wuhan, Xinwei Li, Xufang Cui, Linyuan Zhang, Jianning X. [Inhibition of GMA-induced ubiquitination process in 16HBE malignantly transformed cells on protein CD44 and MMP14]. Wei sheng yan jiu = Journal of hygiene research. vol 52. issue 6. 2023-12-20. PMID:38115649. |
to observe the effect of the ubiquitination process on the expression of cd44 antigen(cd44) and matrix metalloproteinase-14(mmp14) in human bronchial epithelial(16hbe) malignantly transformed cells induced by glycidyl methacrylate(gma). |
2023-12-20 |
2023-12-23 |
human |
| Haijuan Dai, Liting Xu, Maowang Jiang, Weiwei Zhang, Qingxi Ha. Comparative proteomic analysis of the protein profile in the cuttlefish Sepia pharaonis associated with skin ulceration syndrome. Fish & shellfish immunology. 2023-12-01. PMID:38040138. |
real-time reverse transcriptase pcr was used to identify the expression of two differentially expressed matrix metalloproteinases (mmps), and the results showed that the mrna expression of mmp14 and mmp19 was significantly upregulated in the skin tissue of the diseased group. |
2023-12-01 |
2023-12-10 |
Not clear |
| Hyun Lee, Lucas Ibrahimi, Kyu-Yeon Ha. Fluorescence-Based Peptidolytic Assay for High-Throughput Screening of MMP14 Inhibitors. Methods in molecular biology (Clifton, N.J.). vol 2747. 2023-12-01. PMID:38038944. |
the membrane-bound matrix metalloproteinase 14 (mmp14, also known as mt1-mmp) plays important roles in the remodeling of the extracellular matrix during various cellular processes such as cancer metastasis, angiogenesis, and wound healing through its proteolytic activity. |
2023-12-01 |
2023-12-10 |
Not clear |
| Yoshifumi Ito. Investigation of MT1-MMP Activity in Cancer Cells. Methods in molecular biology (Clifton, N.J.). vol 2747. 2023-12-01. PMID:38038939. |
membrane-type 1 matrix metalloproteinase (mt1-mmp, also called mmp14) is one of the significant cell invasion drivers. |
2023-12-01 |
2023-12-10 |
Not clear |
| Wei Li, Linyan Liu, Ming'ai Duanqing, Xiaoqing Xiong, Dejian Gan, Jin Yang, Mingya Wang, Min Zhou, Jun Ya. CLDN1 silencing suppresses the proliferation and migration of airway smooth muscle cells by modulating MMP14. Autoimmunity. vol 56. issue 1. 2023-11-15. PMID:37964516. |
protein-protein interaction assay and co-immunoprecipitation revealed that cldn1 directly interacted with matrix metalloproteinase 14 (mmp14). |
2023-11-15 |
2023-11-20 |
Not clear |
| Ruoqing Cai, Caitlin M Tressler, Menglin Cheng, Kanchan Sonkar, Zheqiong Tan, Santosh Kumar Paidi, Vinay Ayyappan, Ishan Barman, Kristine Glund. Primary breast tumor induced extracellular matrix remodeling in premetastatic lungs. Scientific reports. vol 13. issue 1. 2023-10-31. PMID:37903851. |
premetastatic lungs contained significantly upregulated collagen (col) col4a5, matrix metalloproteinases (mmps) mmp9 and mmp14, and decreased levels of mmp13 and lysyl oxidase (lox) as compared to control lungs. |
2023-10-31 |
2023-11-08 |
mouse |
| Jane B Maoga, Muhammad A Riaz, Agnes N Mwaura, Ezekiel Mecha, Charles O A Omwandho, Georgios Scheiner-Bobis, Ivo Meinhold-Heerlein, Lutz Konra. Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP, MMP14) in Eutopic and Ectopic Endometrium and in Serum and Endocervical Mucus of Endometriosis. Biomedicines. vol 11. issue 10. 2023-10-30. PMID:37893104. |
analysis of membrane type-1 matrix metalloproteinase (mt1-mmp, mmp14) in eutopic and ectopic endometrium and in serum and endocervical mucus of endometriosis. |
2023-10-30 |
2023-11-08 |
human |