| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanan Zhang, Yufen Liu, Yanyan Shi, Chunyu Bai, Ting Wang, Fang Ruan, Chuanbing H. Upregulation of MMPs in placentas of patients with gestational diabetes mellitus: Involvement of the PI3K/Akt pathway. Heliyon. vol 10. issue 12. 2024-07-18. PMID:39021921. |
subsequent analysis indicated that the expression levels of matrix metalloproteinases (mmp) 11, mmp12, mmp14, and mmp15, which are regulated by the pi3k/akt pathway, were upregulated in the placentas of patients with gdm when compared to those of individuals with normal placental function. |
2024-07-18 |
2024-07-20 |
Not clear |
| Xiaoyan Li, Jian Zhao, Lei Chen, Xinyi Zhou, Minglong Qiu, Lianfu Deng, Kai Yang, Yaozeng X. HIF-1α activation impairs dendrites formation and elongation in osteocytogenesis. Heliyon. vol 10. issue 12. 2024-07-16. PMID:39005918. |
this process is followed by activation of the erm/rhoa pathway and recruitment of matrix metalloproteinase 14 (mmp14) to facilitate extracellular matrix degradation, enabling dendrite elongation. |
2024-07-16 |
2024-07-18 |
Not clear |
| Farideh Sabeh, Xiao-Yan Li, Adam W Olson, Elliot Botvinick, Abhishek Kurup, Luis E Gimenez, Jung-Sun Cho, Stephen J Weis. Mmp14-dependent remodeling of the pericellular-dermal collagen interface governs fibroblast survival. The Journal of cell biology. vol 223. issue 9. 2024-07-11. PMID:38990714. |
coincident with this biosynthetic program, fibroblasts proteolytically remodel pericellular collagen fibrils by mobilizing the membrane-anchored matrix metalloproteinase, mmp14. |
2024-07-11 |
2024-07-14 |
mouse |
| Richa Shrivastava, Puneet Gandhi, Sandeep K Sorte, Adesh Shrivastav. Characterizing the Linkage of Systemic Hypoxia and Angiogenesis in High-Grade Glioma to Define the Changes in Tumor Microenvironment for Predicting Prognosis. Journal of molecular neuroscience : MN. vol 74. issue 3. 2024-07-05. PMID:38967861. |
herein, markers representing four components of the tumor microenvironment (tme) were identified to define their linked expression in tme and predict the prognosis in hgg, namely, interleukin6 (il6, inflammation), inducible nitric oxide synthase(inos), heat shock protein-70 (hsp70, hypoxia), vascular endothelial growth receptor (vegf), and endothelin1 (et1) (angiogenesis) and matrix metalloprotease-14 (mmp14) and intercellular adhesion molecule1 (icam1, extracellular matrix). |
2024-07-05 |
2024-07-11 |
Not clear |
| Luqi Qiu, Haijiao Xu, Binglin Sui, Pengwei Jiang, Jiaqi Wang, Dandan Xu, Feng Liang, Tao Ma, Hongda Wang, Junling Che. Elucidating the Functional Mechanism of PTK7 in Cancer Development through Spatial Assembly Analysis Using Super Resolution Imaging. Analytical chemistry. 2024-05-06. PMID:38708542. |
furthermore, we discovered that the spatial distribution morphology of ptk7 was also subject to the hydrolysis ability and activation state of the related hydrolase matrix metallopeptidase14 (mmp14). |
2024-05-06 |
2024-05-08 |
human |
| Signe Meng, Ester E Sørensen, Muthulakshmi Ponniah, Jeppe Thorlacius-Ussing, Roxane Crouigneau, Tanja Larsen, Magnus T Borre, Nicholas Willumsen, Mette Flinck, Stine F Pederse. MCT4 and CD147 co-localize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells. Journal of cell science. 2024-04-25. PMID:38661040. |
mct4 and cd147 co-localize with mmp14 in invadopodia and support matrix degradation and invasion by breast cancer cells. |
2024-04-25 |
2024-04-28 |
Not clear |
| Dan Peng, Juan Li, Yin Li, Lingling Bai, Anying Xiong, Xiang He, Xiaolan Li, Qin Ran, Lei Zhang, Manling Jiang, Junyi Wang, Elaine Lai-Han Leung, Pingchang Yang, Guoping L. MMP14 Pharmacological research. 2024-01-13. PMID:38218353. |
in this study, a decision tree model showed that matrix metalloproteinase-14 (mmp14) had higher scores for important features in the up-regulated genes in macrophages from mice exposed to the saccharopolyspora rectivirgula antigen (sr-ag). |
2024-01-13 |
2024-01-16 |
mouse |
| Huiping Jin, Quankai Wang, Yiting Gu, Baolier Wuhan, Xinwei Li, Xufang Cui, Linyuan Zhang, Jianning X. [Inhibition of GMA-induced ubiquitination process in 16HBE malignantly transformed cells on protein CD44 and MMP14]. Wei sheng yan jiu = Journal of hygiene research. vol 52. issue 6. 2023-12-20. PMID:38115649. |
to observe the effect of the ubiquitination process on the expression of cd44 antigen(cd44) and matrix metalloproteinase-14(mmp14) in human bronchial epithelial(16hbe) malignantly transformed cells induced by glycidyl methacrylate(gma). |
2023-12-20 |
2023-12-23 |
human |
| Haijuan Dai, Liting Xu, Maowang Jiang, Weiwei Zhang, Qingxi Ha. Comparative proteomic analysis of the protein profile in the cuttlefish Sepia pharaonis associated with skin ulceration syndrome. Fish & shellfish immunology. 2023-12-01. PMID:38040138. |
real-time reverse transcriptase pcr was used to identify the expression of two differentially expressed matrix metalloproteinases (mmps), and the results showed that the mrna expression of mmp14 and mmp19 was significantly upregulated in the skin tissue of the diseased group. |
2023-12-01 |
2023-12-10 |
Not clear |
| Hyun Lee, Lucas Ibrahimi, Kyu-Yeon Ha. Fluorescence-Based Peptidolytic Assay for High-Throughput Screening of MMP14 Inhibitors. Methods in molecular biology (Clifton, N.J.). vol 2747. 2023-12-01. PMID:38038944. |
the membrane-bound matrix metalloproteinase 14 (mmp14, also known as mt1-mmp) plays important roles in the remodeling of the extracellular matrix during various cellular processes such as cancer metastasis, angiogenesis, and wound healing through its proteolytic activity. |
2023-12-01 |
2023-12-10 |
Not clear |
| Yoshifumi Ito. Investigation of MT1-MMP Activity in Cancer Cells. Methods in molecular biology (Clifton, N.J.). vol 2747. 2023-12-01. PMID:38038939. |
membrane-type 1 matrix metalloproteinase (mt1-mmp, also called mmp14) is one of the significant cell invasion drivers. |
2023-12-01 |
2023-12-10 |
Not clear |
| Wei Li, Linyan Liu, Ming'ai Duanqing, Xiaoqing Xiong, Dejian Gan, Jin Yang, Mingya Wang, Min Zhou, Jun Ya. CLDN1 silencing suppresses the proliferation and migration of airway smooth muscle cells by modulating MMP14. Autoimmunity. vol 56. issue 1. 2023-11-15. PMID:37964516. |
protein-protein interaction assay and co-immunoprecipitation revealed that cldn1 directly interacted with matrix metalloproteinase 14 (mmp14). |
2023-11-15 |
2023-11-20 |
Not clear |
| Ruoqing Cai, Caitlin M Tressler, Menglin Cheng, Kanchan Sonkar, Zheqiong Tan, Santosh Kumar Paidi, Vinay Ayyappan, Ishan Barman, Kristine Glund. Primary breast tumor induced extracellular matrix remodeling in premetastatic lungs. Scientific reports. vol 13. issue 1. 2023-10-31. PMID:37903851. |
premetastatic lungs contained significantly upregulated collagen (col) col4a5, matrix metalloproteinases (mmps) mmp9 and mmp14, and decreased levels of mmp13 and lysyl oxidase (lox) as compared to control lungs. |
2023-10-31 |
2023-11-08 |
mouse |
| Jane B Maoga, Muhammad A Riaz, Agnes N Mwaura, Ezekiel Mecha, Charles O A Omwandho, Georgios Scheiner-Bobis, Ivo Meinhold-Heerlein, Lutz Konra. Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP, MMP14) in Eutopic and Ectopic Endometrium and in Serum and Endocervical Mucus of Endometriosis. Biomedicines. vol 11. issue 10. 2023-10-30. PMID:37893104. |
analysis of membrane type-1 matrix metalloproteinase (mt1-mmp, mmp14) in eutopic and ectopic endometrium and in serum and endocervical mucus of endometriosis. |
2023-10-30 |
2023-11-08 |
human |
| Jane B Maoga, Muhammad A Riaz, Agnes N Mwaura, Ezekiel Mecha, Charles O A Omwandho, Georgios Scheiner-Bobis, Ivo Meinhold-Heerlein, Lutz Konra. Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP, MMP14) in Eutopic and Ectopic Endometrium and in Serum and Endocervical Mucus of Endometriosis. Biomedicines. vol 11. issue 10. 2023-10-30. PMID:37893104. |
membrane type-1 matrix metalloproteinase (mt1-mmp, mmp14) is often deregulated in different cancer tissues and body fluids of human cancer patients; however, mt1-mmp levels in endometriosis and adenomyosis patients are currently unknown. |
2023-10-30 |
2023-11-08 |
human |
| Anuja Pant, Tikam Chand Dakal, Kareena Moar, Bhanupriya Dhabhai, Taruna K Arora, Narendra Kumar Sharma, Vipin Ranga, Pawan Kumar Maury. Assessment of MMP14, CAV2, CLU and SPARCL1 expression profiles in endometriosis. Pathology, research and practice. vol 251. 2023-10-28. PMID:37898038. |
in this regard, do matrix metalloproteinases 14 (mmp14) and other related genes such as sparc-like protein 1 (sparcl1), caveolin 2 (cav2), and clusterin (clu) exert any significant influence in the processes of endometriosis development and pathophysiology is not apparent. |
2023-10-28 |
2023-11-08 |
Not clear |
| Syed K Imam, Dhekra Alnaqeb, Mohammad Bedaiwi, Ebtissal M Khou. Multicentric Osteolysis Nodulosis Arthropathy Syndrome Simulating Juvenile Idiopathic Arthritis in an Adult Female: A Case Report and a Literature Review. Cureus. vol 15. issue 9. 2023-10-16. PMID:37842447. |
mona syndrome includes diseases involving two genes: the matrix metalloproteinase 2 (mmp2) gene and matrix metalloproteinase 14 (mmp14). |
2023-10-16 |
2023-11-08 |
Not clear |
| Tianyu Zhao, Xue Li, Mingfeng Li, Muhammad Jamil, Jingyu Zhan. Characterization and verification of MMP family members as potential biomarkers in kidney clear cell renal carcinoma. American journal of cancer research. vol 13. issue 9. 2023-10-11. PMID:37818055. |
by performing string and cytohubba analyses of the 24 mmp gene family members, mmp2 (matrix metallopeptidase 2), mmp9 (matrix metallopeptidase 9), mmp14 (matrix metallopeptidase 14), and mmp16 (matrix metallopeptidase 16) were recognized as hub genes having highest degree scores. |
2023-10-11 |
2023-10-15 |
human |
| Chiao-Yun Lin, Kai-Yun Wu, Lang-Ming Chi, Yun-Hsin Tang, Huei-Jean Huang, Chyong-Huey Lai, Chi-Neu Tsai, Chia-Lung Tsa. Starvation-inactivated MTOR triggers cell migration via a ULK1-SH3PXD2A/TKS5-MMP14 pathway in ovarian carcinoma. Autophagy. 2023-07-28. PMID:37505094. |
ampk: amp-activated protein kinase; chx: cycloheximide; rad001: everolimus; hbss: hanks' balanced salt solution; lc-ms/ms: liquid chromatography-mass spectrometry/mass spectrometry; mmp14: matrix metallopeptidase 14; mtor: mechanistic target of rapamycin kinase; mapk: mitogen-activated protein kinase; rb1cc1/fip200: rb1 inducible coiled-coil 1; ptdins3p: phosphatidylinositol-3-phosphate; px: phox homology; sh3: src homology 3; sh3pxd2a/tks5: sh3 and px domains 2a; sh3pxd2a-[6a]: s112a s142a s146a s147a s175a s348a mutant; ulk1: unc-51 like autophagy activating kinase 1. |
2023-07-28 |
2023-08-14 |
Not clear |
| Astha Sachan, Sandeep Aggarwal, Manjunath Maruti Pol, Archna Singh, Rakhee Yada. Expression analysis of MMP14: Key enzyme action in modulating visceral adipose tissue plasticity in patients with obesity. Clinical obesity. 2023-06-21. PMID:37340990. |
collagen6 (col6) is well characterized in obese visceral adipose tissue (vat), not much is known about mmp14 which is hypothesized to be the key player in matrix reorganization. |
2023-06-21 |
2023-08-14 |
human |