| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maike Kümper, Jan Zamek, Joy Steinkamp, Elke Pach, Cornelia Mauch, Paola Zigrin. Role of MMP3 and fibroblast-MMP14 in skin homeostasis and repair. European journal of cell biology. vol 101. issue 4. 2022-09-26. PMID:36162272. |
early lethality of mice with complete deletion of the matrix metalloproteinase mmp14 emphasized the proteases' pleiotropic functions. |
2022-09-26 |
2023-08-14 |
mouse |
| Yuji Kanazawa, Tatsuo Takahashi, Takashi Higuchi, Ryo Miyachi, Mamoru Nagano, Satoshi Koinuma, Yasufumi Shigeyosh. Effects of stretching on the basement membrane structure in the soleus muscle of Wistar rats. Medical molecular morphology. 2022-09-15. PMID:36107241. |
the results show that stretching increased the matrix metalloproteinase 14 (mmp14) expression and mmp2 activity, and decreased the collagen iv expression and width of the lamina densa in the soleus muscle. |
2022-09-15 |
2023-08-14 |
rat |
| Yusuke Makutani, Hisato Kawakami, Takahiro Tsujikawa, Kanako Yoshimura, Yasutaka Chiba, Akihiko Ito, Junichiro Kawamura, Koji Haratani, Kazuhiko Nakagaw. Contribution of MMP14-expressing cancer-associated fibroblasts in the tumor immune microenvironment to progression of colorectal cancer. Frontiers in oncology. vol 12. 2022-09-02. PMID:36052235. |
matrix metalloproteinase 14 (mmp14) expression is implicated in progression of colorectal cancer, but its role in the tumor microenvironment (tme) has been unclear. |
2022-09-02 |
2023-08-14 |
Not clear |
| Pilar Puerto-Camacho, Juan Díaz-Martín, Joaquín Olmedo-Pelayo, Alfonso Bolado-Carrancio, Carmen Salguero-Aranda, Carmen Jordán-Pérez, Marina Esteban-Medina, Inmaculada Álamo-Álvarez, Daniel Delgado-Bellido, Laura Lobo-Selma, Joaquín Dopazo, Ana Sastre, Javier Alonso, Thomas G P Grünewald, Carmelo Bernabeu, Adam Byron, Valerie G Brunton, Ana Teresa Amaral, Enrique De Álav. Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell-Matrix Interactions. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955799. |
this transmembrane glycoprotein is shed by matrix metalloproteinase 14 (mmp14). |
2022-08-12 |
2023-08-14 |
Not clear |
| Pilar Puerto-Camacho, Juan Díaz-Martín, Joaquín Olmedo-Pelayo, Alfonso Bolado-Carrancio, Carmen Salguero-Aranda, Carmen Jordán-Pérez, Marina Esteban-Medina, Inmaculada Álamo-Álvarez, Daniel Delgado-Bellido, Laura Lobo-Selma, Joaquín Dopazo, Ana Sastre, Javier Alonso, Thomas G P Grünewald, Carmelo Bernabeu, Adam Byron, Valerie G Brunton, Ana Teresa Amaral, Enrique De Álav. Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell-Matrix Interactions. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955799. |
in turn, loss of mmp14 contributed to a more adhesive phenotype of es cells by modulating the transcriptional extracellular matrix dynamics. |
2022-08-12 |
2023-08-14 |
Not clear |
| Frank Xu, Li-Lun Ho, You-Hsien H Lin, Tzongshi L. Inhibiting ADAM10-MMP14 Complex Blocks Cystogenesis of Kidney Epithelial Cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554426. |
a disintegrin-like metalloproteinase 10 (adam10) and matrix metalloproteinase 14 (mmp14) are two major members in the superfamily of metalloproteinases that primarily cleave several cell membrane proteins and growth factors. |
2022-05-13 |
2023-08-13 |
rat |
| Allyson C Banville, Brad H Nelso. Breaching B cell tolerance in the tumor microenvironment. Cancer cell. vol 40. issue 4. 2022-04-12. PMID:35413269. |
report that autoantibodies produced by tumor-infiltrating b cells in human ovarian cancer frequently recognize the self-protein matrix metalloproteinase 14 (mmp14) through two distinct mechanisms of tolerance disruption. |
2022-04-12 |
2023-08-13 |
human |
| Sara M Centuori, Deepta Bhattachary. Locally produced autoantibodies in cancer. Cell. vol 185. issue 7. 2022-04-01. PMID:35364029. |
in a new study by mazor et al., matrix metalloproteinase 14 (mmp14), a self-antigen that is overexpressed by ovarian cancers, is shown to drive b cell activation and autoantibody production in tertiary lymphoid structures (mazor et al., 2022). |
2022-04-01 |
2023-08-13 |
Not clear |
| Danfeng Guo, Xiaodan Zhang, Honglei Cui, Dongsheng Yu, Huapeng Zhang, Xiaoyi Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhan. ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14. Frontiers in oncology. vol 12. 2022-02-17. PMID:35174091. |
expression of matrix metalloproteinase-14 (mmp14) was negatively associated with the content of acadl in hcc specimens. |
2022-02-17 |
2023-08-13 |
Not clear |
| Yang Li, Min Li, Caijie Qu, Yongxi Li, Zhanli Tang, Zhike Zhou, Zengzhao Yu, Xu Wang, Linlin Xin, Tongxin Sh. The Polygenic Map of Keloid Fibroblasts Reveals Fibrosis-Associated Gene Alterations in Inflammation and Immune Responses. Frontiers in immunology. vol 12. 2022-01-27. PMID:35082796. |
for example, il17ra is involved in il-17 signal transduction, timp2 and mmp14 activate extracellular matrix metalloproteinases, and tnc, itgb2, and itga4 interact with cell surface integrins. |
2022-01-27 |
2023-08-13 |
Not clear |
| Xueqing Zhou, Shuya Yang, Qianqian Liu, Ran Wei, Jing Liu, Naixiang Luo, Wenhui Li. [Leptin promotes the proliferation and migration of MDA-MB-231 breast cancer cells by up regulating MMP14]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 1. 2022-01-26. PMID:35078574. |
objective to investigate the effect of matrix metalloproteinase 14 (mmp14) on the proliferation and migration of mda-mb-231 human breast cancer cells treated with leptin. |
2022-01-26 |
2023-08-13 |
human |
| Bailey D Peck, Kevin A Murach, R Grace Walton, Alexander J Simmons, Douglas E Long, Kate Kosmac, Cory M Dungan, Philip A Kern, Marcas M Bamman, Charlotte A Peterso. A muscle cell-macrophage axis involving matrix metalloproteinase 14 facilitates extracellular matrix remodeling with mechanical loading. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 2. 2022-01-19. PMID:35044708. |
in a large cohort of older adults, transcriptomics revealed that genes involved in ecm remodeling, including matrix metalloproteinase 14 (mmp14), were the most upregulated following 14 weeks of progressive resistance exercise training (prt). |
2022-01-19 |
2023-08-13 |
mouse |
| Eleni Petra, Justyna Siwy, Antonia Vlahou, Joachim Jankowsk. Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease. PloS one. vol 17. issue 1. 2022-01-19. PMID:35045102. |
through investigating ckd-associated transcriptomics datasets, several proteases are highlighted including members of matrix metalloproteinases (mmp7, mmp14) and serine proteases (pcsk5); laying the foundation for further studies towards elucidating their role in ckd pathophysiology. |
2022-01-19 |
2023-08-13 |
Not clear |
| Chun-Long Zheng, Qiang Lu, Nian Zhang, Peng-Yu Jing, Ji-Peng Zhang, Wu-Ping Wang, Gui-Zhen L. Comprehensive Analysis of the Immune and Prognostic Implication of MMP14 in Lung Cancer. Disease markers. vol 2021. 2021-12-08. PMID:34868395. |
matrix metalloproteinase 14 (mmp14) has been reported to be dysregulated in many types of tumors and involved in the development and progression of tumors. |
2021-12-08 |
2023-08-13 |
Not clear |
| Yimin Huang, Baole Zhang, Hannah Haneke, Verena Haage, Malgorzata Lubas, Yang Yuan, Pengfei Xia, Edyta Motta, Cynthia Nanvuma, Omar Dzaye, Feng Hu, Helmut Kettenman. Glial cell line-derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia-mediated glioma progression. Journal of neuroscience research. vol 99. issue 4. 2021-11-30. PMID:33404121. |
here we show that gdnf increases matrix metalloproteinase (mmp) 9 and mmp14 expression in cultured microglial cells from mixed sexes of neonatal mice. |
2021-11-30 |
2023-08-13 |
mouse |
| Elke Pach, Maike Kümper, Julia E Fromme, Jan Zamek, Fabian Metzen, Manuel Koch, Cornelia Mauch, Paola Zigrin. Extracellular Matrix Remodeling by Fibroblast-MMP14 Regulates Melanoma Growth. International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830157. |
one of these proteases is the matrix metalloproteinase 14 (mmp14). |
2021-11-30 |
2023-08-13 |
mouse |
| Elke Pach, Maike Kümper, Julia E Fromme, Jan Zamek, Fabian Metzen, Manuel Koch, Cornelia Mauch, Paola Zigrin. Extracellular Matrix Remodeling by Fibroblast-MMP14 Regulates Melanoma Growth. International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830157. |
this study shows that loss of fibroblast-mmp14 affects melanoma growth through altering the peritumoral extracellular matrix (ecm) composition, with collagen xiv being a modulator of melanoma progression and a new proteolytic substrate to mmp14. |
2021-11-30 |
2023-08-13 |
mouse |
| Akikazu Harada, Shinji Matsumoto, Yoshiaki Yasumizu, Kensaku Shojima, Toshiyuki Akama, Hidetoshi Eguchi, Akira Kikuch. Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion. eLife. vol 10. 2021-11-20. PMID:34590580. |
specific localization of arl4c, iqgap1, and mmp14 was the active site of invasion, which induced degradation of the extracellular matrix. |
2021-11-20 |
2023-08-13 |
mouse |
| Xiao-Guang Yang, Yan-Yu Li, Dong-Xue Zhao, Wei Cui, Han Li, Xin-Yu Li, Yu-Xin Li, Dun Wan. Repurposing of a monoamine oxidase A inhibitor‑heptamethine carbocyanine dye conjugate for paclitaxel‑resistant non‑small cell lung cancer. Oncology reports. vol 45. issue 3. 2021-10-22. PMID:33650669. |
gene expression profiling of paclitaxel‑resistant nsclc cells following treatment with g10 demonstrated that the expression of genes associated with the extracellular matrix was significantly affected, particularly the metastasis‑related genes matrix metallopeptidase (mmp)2, mmp14 and col6a, which exhibited notably reduced expression. |
2021-10-22 |
2023-08-13 |
mouse |
| Aiman Ali, Andresa Borges Soares, Denise Eymael, Marco Magalhae. Expression of invadopodia markers can identify oral lesions with a high risk of malignant transformation. The journal of pathology. Clinical research. vol 7. issue 1. 2021-10-13. PMID:33001588. |
all samples were stained for cortactin, tyrosine kinase substrate with five sh3 domains (tks5) and matrix metallopeptidase 14 (mmp14) using fihc, imaged using confocal microscopy and analyzed using a multichannel colocalization analysis. |
2021-10-13 |
2023-08-13 |
Not clear |