| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lauren E King, Hui-Hua Zhang, Cathryn M Gould, Daniel W Thomas, Lachlan W Whitehead, Kaylene J Simpson, Antony W Burgess, Maree C Fau. Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen. PloS one. vol 15. issue 10. 2020-12-09. PMID:33057364. |
among the genes whose depletion promotes membrane-associated e-cadherin, we identified zeb1, the microrna200 family, and proteins such as a ubiquitin ligase ube2e3, cdk8, sorting nexin 27 (snx27) and the matrix metalloproteinases, mmp14 and mmp19. |
2020-12-09 |
2023-08-13 |
Not clear |
| Ilja L Kruglikov, Nolwenn Joffin, Philipp E Schere. The MMP14-caveolin axis and its potential relevance for lipoedema. Nature reviews. Endocrinology. vol 16. issue 11. 2020-12-04. PMID:32792644. |
we suggest that lipoedema is an oestrogen-dependent disorder of adipose tissue, which is triggered by a dysfunction of caveolin 1 (cav1) and subsequent uncoupling of feedback mechanisms between cav1, the matrix metalloproteinase mmp14 and oestrogen receptors. |
2020-12-04 |
2023-08-13 |
Not clear |
| Lena Claesson-Wels. How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer. The Journal of clinical investigation. vol 130. issue 3. 2020-10-27. PMID:32015228. |
how the matrix metalloproteinase mmp14 contributes to the progression of colorectal cancer. |
2020-10-27 |
2023-08-13 |
mouse |
| Lena Claesson-Wels. How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer. The Journal of clinical investigation. vol 130. issue 3. 2020-10-27. PMID:32015228. |
these tumors showed downregulated levels of the transcription factor prospero homeobox protein 1 (prox1), which relieved repression of the matrix metalloproteinase mmp14. |
2020-10-27 |
2023-08-13 |
mouse |
| Kuo-Shun Hsu, Wataru Otsu, Yao Li, Heuy-Ching Wang, Shuibing Chen, Stephen H Tsang, Jen-Zen Chuang, Ching-Hwa Sun. CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31439888. |
clic4 regulates late endosomal trafficking and matrix degradation activity of mmp14 at focal adhesions in rpe cells. |
2020-10-22 |
2023-08-13 |
human |
| Kuo-Shun Hsu, Wataru Otsu, Yao Li, Heuy-Ching Wang, Shuibing Chen, Stephen H Tsang, Jen-Zen Chuang, Ching-Hwa Sun. CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31439888. |
we show that membrane-type matrix metalloproteinase 14 (mmp14) is central to ecm degradation at the focal adhesions in human arpe19 cells. |
2020-10-22 |
2023-08-13 |
human |
| Liang Chang, Xuhui Lei, Y U Qin, Xuexin Zhang, Hua Jin, Chao Wang, Xin Wang, Guofu Li, Chunlei Tan, Jun S. MicroRNA-133b inhibits cell migration and invasion by targeting matrix metalloproteinase 14 in glioblastoma. Oncology letters. vol 10. issue 5. 2020-10-01. PMID:26722242. |
it was found that mir-133b suppressed gbm cell migration and invasion, and matrix metalloproteinase 14 (mmp14) was identified as a direct target gene. |
2020-10-01 |
2023-08-13 |
human |
| Li-Li Mei, Yun-Tan Qiu, Wen-Jun Wang, Jie Bai, Zhi-Zhou Sh. Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells. Oncology letters. vol 14. issue 6. 2020-09-30. PMID:29344220. |
it was also revealed that knockdown of mir-1470 significantly inhibited migration, and decreased the expression levels of matrix metalloproteinase 2 (mmp2), mmp13 and mmp14. |
2020-09-30 |
2023-08-13 |
human |
| Xufang Huang, Jinman Zhong, Jing Ren, Didi Wen, Weiwei Zhao, Yi Hua. A DNA aptamer recognizing MMP14 for Oncology letters. vol 18. issue 1. 2020-09-30. PMID:31289496. |
matrix metalloproteinase 14 (mmp14) is overexpressed in numerous types of cancer and is associated with poor prognosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Alicia González-González, Alicia González, Noemí Rueda, Carolina Alonso-González, Javier Menéndez-Menéndez, José Gómez-Arozamena, Carlos Martínez-Campa, Samuel Co. Melatonin Enhances the Usefulness of Ionizing Radiation: Involving the Regulation of Different Steps of the Angiogenic Process. Frontiers in physiology. vol 10. 2020-09-30. PMID:31354524. |
in relation with extracellular matrix molecules, radiation increased mmp14 mrna expression and melatonin counteracted the stimulatory effect of radiation on mmp14 mrna expression and increased timp1 expression, an angiogenesis inhibitor. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ayako Sato, Sei Kakinuma, Masato Miyoshi, Akihide Kamiya, Tomoyuki Tsunoda, Shun Kaneko, Jun Tsuchiya, Taro Shimizu, Eiko Takeichi, Sayuri Nitta, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanab. Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts. Hepatology communications. vol 4. issue 2. 2020-09-28. PMID:32025608. |
to identify candidate factors contributing to this cell-cell interaction, mesenchymal cells were isolated from embryonic day 16.5 matrix metalloproteinase 14 (mmp14)-deficient (knockout [ko]) mice livers, in which ihbd formation is retarded, and compared with those of the wild type (wt). |
2020-09-28 |
2023-08-13 |
mouse |
| Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fa. TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination. Annals of the rheumatic diseases. vol 79. issue 8. 2020-09-28. PMID:32409323. |
tgfβ attenuates cartilage extracellular matrix degradation via enhancing fbxo6-mediated mmp14 ubiquitination. |
2020-09-28 |
2023-08-13 |
Not clear |
| Chengliang Yin, Junyan Zhang, Ming Shen, Zhenyang Gu, Yan Li, Wanguo Xue, Jinlong Shi, Wenrong Huan. Matrix Metallopeptidase 14: A Candidate Prognostic Biomarker for Diffuse Large B-Cell Lymphoma. Frontiers in oncology. vol 10. 2020-09-28. PMID:32974187. |
matrix metallopeptidase 14 (mmp14) is an important gene in the regulation of t-cell function. |
2020-09-28 |
2023-08-13 |
Not clear |
| Aaro Kasurinen, Silvia Gramolelli, Jaana Hagström, Alli Laitinen, Arto Kokkola, Yuichiro Miki, Kaisa Lehti, Masakazu Yashiro, Päivi M Ojala, Camilla Böckelman, Caj Haglun. High tissue MMP14 expression predicts worse survival in gastric cancer, particularly with a low PROX1. Cancer medicine. vol 8. issue 16. 2020-09-24. PMID:31560170. |
matrix metalloproteinase 14 (mmp14), a membrane-associated matrix metalloproteinase, has been shown to influence the invasion and metastasis of several solid tumors. |
2020-09-24 |
2023-08-13 |
Not clear |
| Guoliang Sa, Zhikang Liu, Jiangang Ren, Qilong Wan, Xuepeng Xiong, Zili Yu, Heng Chen, Yifang Zhao, Sangang H. Cellular signalling. vol 61. 2020-08-21. PMID:31082464. |
moreover, podosomal components including integrin α6，β4，α3，β1 and mmp14 colocalized with the f-actin-cortactin complex and matrix degradation assays demonstrated the ability of the f-actin-cortactin complex to degrade matrix. |
2020-08-21 |
2023-08-13 |
human |
| Xin Li, Yueshui Zhao, Chuan Chen, Li Yang, Hyun-Ho Lee, Zening Wang, Ningyan Zhang, Mikhail G Kolonin, Zhiqiang An, Xin Ge, Philipp E Scherer, Kai Su. Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity. Molecular and cellular biology. vol 40. issue 8. 2020-08-19. PMID:31988105. |
here, we reported that matrix metalloproteinase 14 (mmp14), a key pericellular collagenase, is dramatically upregulated in obese adipose tissue. |
2020-08-19 |
2023-08-13 |
mouse |
| Xin Li, Yueshui Zhao, Chuan Chen, Li Yang, Hyun-Ho Lee, Zening Wang, Ningyan Zhang, Mikhail G Kolonin, Zhiqiang An, Xin Ge, Philipp E Scherer, Kai Su. Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity. Molecular and cellular biology. vol 40. issue 8. 2020-08-19. PMID:31988105. |
this unique metabolic phenotype is likely due to digestion/modification of the dense adipose tissue extracellular matrix by mmp14, thereby releasing the mechanical stress to allow for its healthy expansion. |
2020-08-19 |
2023-08-13 |
mouse |
| b' Mich\\xc3\\xa8le Bengue, Pauline Ferraris, C\\xc3\\xa9cile Baronti, Cheikh Tidiane Diagne, Lo\\xc3\\xafc Talignani, Sineewanlaya Wichit, Florian Liegeois, Catherine Bisbal, Antoine Nougair\\xc3\\xa8de, Doroth\\xc3\\xa9e Miss\\xc3\\xa. Mayaro Virus Infects Human Chondrocytes and Induces the Expression of Arthritis-Related Genes Associated with Joint Degradation. Viruses. vol 11. issue 9. 2020-07-31. PMID:31470617.' |
the infection of the latter cells resulted in an induction in the expression of several matrix metalloproteinases (mmp) including mmp1, mmp7, mmp8, mmp10, mmp13, mmp14 and mmp15 which could be involved in the destruction of articular cartilage. |
2020-07-31 |
2023-08-13 |
human |
| Ivo J H M de Vos, Arnette Shi Wei Wong, Tim J M Welting, Barry J Coull, Maurice A M van Steense. Multicentric osteolytic syndromes represent a phenotypic spectrum defined by defective collagen remodeling. American journal of medical genetics. Part A. vol 179. issue 8. 2020-07-28. PMID:31218820. |
these autosomal recessive syndromes are caused by homozygous mutation or deletion of respectively sh3pxd2b (sh3 and px domains 2b), mmp14 (matrix metalloproteinase 14), or mmp2. |
2020-07-28 |
2023-08-13 |
Not clear |
| Ilya V Ulasov, Olja Mijanovic, Solomiia Savchuk, Edgar Gonzalez-Buendia, Adam Sonabend, Ting Xiao, Petr Timashev, Maciej S Lesnia. TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway. International journal of cancer. vol 146. issue 8. 2020-05-18. PMID:31443114. |
the objective of our study was to investigate gbm resistance mediated via mmp14 (matrix metalloproteinase 14). |
2020-05-18 |
2023-08-13 |
Not clear |