| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kuo-Shun Hsu, Wataru Otsu, Yao Li, Heuy-Ching Wang, Shuibing Chen, Stephen H Tsang, Jen-Zen Chuang, Ching-Hwa Sun. CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31439888. |
we show that membrane-type matrix metalloproteinase 14 (mmp14) is central to ecm degradation at the focal adhesions in human arpe19 cells. |
2020-10-22 |
2023-08-13 |
human |
| Liang Chang, Xuhui Lei, Y U Qin, Xuexin Zhang, Hua Jin, Chao Wang, Xin Wang, Guofu Li, Chunlei Tan, Jun S. MicroRNA-133b inhibits cell migration and invasion by targeting matrix metalloproteinase 14 in glioblastoma. Oncology letters. vol 10. issue 5. 2020-10-01. PMID:26722242. |
it was found that mir-133b suppressed gbm cell migration and invasion, and matrix metalloproteinase 14 (mmp14) was identified as a direct target gene. |
2020-10-01 |
2023-08-13 |
human |
| Li-Li Mei, Yun-Tan Qiu, Wen-Jun Wang, Jie Bai, Zhi-Zhou Sh. Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells. Oncology letters. vol 14. issue 6. 2020-09-30. PMID:29344220. |
it was also revealed that knockdown of mir-1470 significantly inhibited migration, and decreased the expression levels of matrix metalloproteinase 2 (mmp2), mmp13 and mmp14. |
2020-09-30 |
2023-08-13 |
human |
| Xufang Huang, Jinman Zhong, Jing Ren, Didi Wen, Weiwei Zhao, Yi Hua. A DNA aptamer recognizing MMP14 for Oncology letters. vol 18. issue 1. 2020-09-30. PMID:31289496. |
matrix metalloproteinase 14 (mmp14) is overexpressed in numerous types of cancer and is associated with poor prognosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Alicia González-González, Alicia González, Noemí Rueda, Carolina Alonso-González, Javier Menéndez-Menéndez, José Gómez-Arozamena, Carlos Martínez-Campa, Samuel Co. Melatonin Enhances the Usefulness of Ionizing Radiation: Involving the Regulation of Different Steps of the Angiogenic Process. Frontiers in physiology. vol 10. 2020-09-30. PMID:31354524. |
in relation with extracellular matrix molecules, radiation increased mmp14 mrna expression and melatonin counteracted the stimulatory effect of radiation on mmp14 mrna expression and increased timp1 expression, an angiogenesis inhibitor. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ayako Sato, Sei Kakinuma, Masato Miyoshi, Akihide Kamiya, Tomoyuki Tsunoda, Shun Kaneko, Jun Tsuchiya, Taro Shimizu, Eiko Takeichi, Sayuri Nitta, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanab. Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts. Hepatology communications. vol 4. issue 2. 2020-09-28. PMID:32025608. |
to identify candidate factors contributing to this cell-cell interaction, mesenchymal cells were isolated from embryonic day 16.5 matrix metalloproteinase 14 (mmp14)-deficient (knockout [ko]) mice livers, in which ihbd formation is retarded, and compared with those of the wild type (wt). |
2020-09-28 |
2023-08-13 |
mouse |
| Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fa. TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination. Annals of the rheumatic diseases. vol 79. issue 8. 2020-09-28. PMID:32409323. |
tgfβ attenuates cartilage extracellular matrix degradation via enhancing fbxo6-mediated mmp14 ubiquitination. |
2020-09-28 |
2023-08-13 |
Not clear |
| Chengliang Yin, Junyan Zhang, Ming Shen, Zhenyang Gu, Yan Li, Wanguo Xue, Jinlong Shi, Wenrong Huan. Matrix Metallopeptidase 14: A Candidate Prognostic Biomarker for Diffuse Large B-Cell Lymphoma. Frontiers in oncology. vol 10. 2020-09-28. PMID:32974187. |
matrix metallopeptidase 14 (mmp14) is an important gene in the regulation of t-cell function. |
2020-09-28 |
2023-08-13 |
Not clear |
| Aaro Kasurinen, Silvia Gramolelli, Jaana Hagström, Alli Laitinen, Arto Kokkola, Yuichiro Miki, Kaisa Lehti, Masakazu Yashiro, Päivi M Ojala, Camilla Böckelman, Caj Haglun. High tissue MMP14 expression predicts worse survival in gastric cancer, particularly with a low PROX1. Cancer medicine. vol 8. issue 16. 2020-09-24. PMID:31560170. |
matrix metalloproteinase 14 (mmp14), a membrane-associated matrix metalloproteinase, has been shown to influence the invasion and metastasis of several solid tumors. |
2020-09-24 |
2023-08-13 |
Not clear |
| Guoliang Sa, Zhikang Liu, Jiangang Ren, Qilong Wan, Xuepeng Xiong, Zili Yu, Heng Chen, Yifang Zhao, Sangang H. Cellular signalling. vol 61. 2020-08-21. PMID:31082464. |
moreover, podosomal components including integrin α6，β4，α3，β1 and mmp14 colocalized with the f-actin-cortactin complex and matrix degradation assays demonstrated the ability of the f-actin-cortactin complex to degrade matrix. |
2020-08-21 |
2023-08-13 |
human |
| Xin Li, Yueshui Zhao, Chuan Chen, Li Yang, Hyun-Ho Lee, Zening Wang, Ningyan Zhang, Mikhail G Kolonin, Zhiqiang An, Xin Ge, Philipp E Scherer, Kai Su. Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity. Molecular and cellular biology. vol 40. issue 8. 2020-08-19. PMID:31988105. |
here, we reported that matrix metalloproteinase 14 (mmp14), a key pericellular collagenase, is dramatically upregulated in obese adipose tissue. |
2020-08-19 |
2023-08-13 |
mouse |
| Xin Li, Yueshui Zhao, Chuan Chen, Li Yang, Hyun-Ho Lee, Zening Wang, Ningyan Zhang, Mikhail G Kolonin, Zhiqiang An, Xin Ge, Philipp E Scherer, Kai Su. Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity. Molecular and cellular biology. vol 40. issue 8. 2020-08-19. PMID:31988105. |
this unique metabolic phenotype is likely due to digestion/modification of the dense adipose tissue extracellular matrix by mmp14, thereby releasing the mechanical stress to allow for its healthy expansion. |
2020-08-19 |
2023-08-13 |
mouse |
| b' Mich\\xc3\\xa8le Bengue, Pauline Ferraris, C\\xc3\\xa9cile Baronti, Cheikh Tidiane Diagne, Lo\\xc3\\xafc Talignani, Sineewanlaya Wichit, Florian Liegeois, Catherine Bisbal, Antoine Nougair\\xc3\\xa8de, Doroth\\xc3\\xa9e Miss\\xc3\\xa. Mayaro Virus Infects Human Chondrocytes and Induces the Expression of Arthritis-Related Genes Associated with Joint Degradation. Viruses. vol 11. issue 9. 2020-07-31. PMID:31470617.' |
the infection of the latter cells resulted in an induction in the expression of several matrix metalloproteinases (mmp) including mmp1, mmp7, mmp8, mmp10, mmp13, mmp14 and mmp15 which could be involved in the destruction of articular cartilage. |
2020-07-31 |
2023-08-13 |
human |
| Ivo J H M de Vos, Arnette Shi Wei Wong, Tim J M Welting, Barry J Coull, Maurice A M van Steense. Multicentric osteolytic syndromes represent a phenotypic spectrum defined by defective collagen remodeling. American journal of medical genetics. Part A. vol 179. issue 8. 2020-07-28. PMID:31218820. |
these autosomal recessive syndromes are caused by homozygous mutation or deletion of respectively sh3pxd2b (sh3 and px domains 2b), mmp14 (matrix metalloproteinase 14), or mmp2. |
2020-07-28 |
2023-08-13 |
Not clear |
| Ilya V Ulasov, Olja Mijanovic, Solomiia Savchuk, Edgar Gonzalez-Buendia, Adam Sonabend, Ting Xiao, Petr Timashev, Maciej S Lesnia. TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway. International journal of cancer. vol 146. issue 8. 2020-05-18. PMID:31443114. |
the objective of our study was to investigate gbm resistance mediated via mmp14 (matrix metalloproteinase 14). |
2020-05-18 |
2023-08-13 |
Not clear |
| Jordi Gonzalez-Molina, Silvia Gramolelli, Zehuan Liao, Joseph W Carlson, Päivi M Ojala, Kaisa Leht. MMP14 in Sarcoma: A Regulator of Tumor Microenvironment Communication in Connective Tissues. Cells. vol 8. issue 9. 2020-05-18. PMID:31466240. |
the expression and function of the membrane-type matrix metalloproteinase mmp14 is closely related to the mesenchymal cell phenotype, and it is highly expressed in most sarcomas. |
2020-05-18 |
2023-08-13 |
Not clear |
| Jordi Gonzalez-Molina, Silvia Gramolelli, Zehuan Liao, Joseph W Carlson, Päivi M Ojala, Kaisa Leht. MMP14 in Sarcoma: A Regulator of Tumor Microenvironment Communication in Connective Tissues. Cells. vol 8. issue 9. 2020-05-18. PMID:31466240. |
mmp14 regulates the activity of multiple extracellular and plasma membrane proteins, influencing cell-cell and cell-extracellular matrix (ecm) communication. |
2020-05-18 |
2023-08-13 |
Not clear |
| Haoyong Li, Qi Li, Zhe Ma, Zhiyan Zhou, Jinfeng Fan, Yingxia Jin, Yaoxi Wu, Fan Cheng, Peiyu Lian. AID modulates carcinogenesis network via DNA demethylation in bladder urothelial cell carcinoma. Cell death & disease. vol 10. issue 4. 2020-05-15. PMID:30874539. |
after a pipeline of bioinformatics analyses, we identified three tumour-associated factors, namely, matrix metallopeptidase 14 (mmp14), c-x-c motif chemokine ligand 12 and wntless wnt ligand secretion mediator, which were further confirmed in human bucc tissues. |
2020-05-15 |
2023-08-13 |
human |
| Pilar Puerto-Camacho, Ana Teresa Amaral, Salah-Eddine Lamhamedi-Cherradi, Brian A Menegaz, Helena Castillo-Ecija, José Luis Ordóñez, Saioa Domínguez, Carmen Jordan-Perez, Juan Diaz-Martin, Laura Romero-Pérez, Maria Lopez-Alvarez, Gema Civantos-Jubera, María José Robles-Frías, Michele Biscuola, Cristina Ferrer, Jaume Mora, Branko Cuglievan, Keri Schadler, Oliver Seifert, Roland Kontermann, Klaus Pfizenmaier, Laureano Simón, Myriam Fabre, Ángel M Carcaboso, Joseph A Ludwig, Enrique de Álav. Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 25. issue 7. 2020-05-11. PMID:30420447. |
it exists both as a transmembrane cell surface protein, where it primarily interacts with tgfβ, and as a soluble matricellular protein (seng) when cleaved by matrix metalloproteinase 14 (mmp14). |
2020-05-11 |
2023-08-13 |
Not clear |
| Hyun-Ouk Kim, Jong-Woo Lim, Jihye Choi, Hwunjae Lee, Hye Young Son, Jihye Kim, Geunseon Park, Haejin Chun, Daesub Song, Yong-Min Huh, Seungjoo Haa. Anchored protease-activatable polymersomes for molecular diagnostics of metastatic cancer cells. Journal of materials chemistry. B. vol 5. issue 48. 2020-04-08. PMID:32264571. |
we designed unique protease-activatable polymersomes (peptisomes) for high sensitivity, in situ quantitative analysis of activating membrane-type 1 matrix metalloproteinases (mt1-mmp, mmp14). |
2020-04-08 |
2023-08-13 |
Not clear |