| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Hauner, G Glatting, D Kaminska, E F Pfeiffe. Effects of gastric inhibitory polypeptide on glucose and lipid metabolism of isolated rat adipocytes. Annals of nutrition & metabolism. vol 32. issue 5-6. 1989-08-29. PMID:3076052. |
insulin binding was slightly but not significantly increased by addition of gip, mainly due to an increase in receptor affinity. |
1989-08-29 |
2023-08-11 |
rat |
| E Peiró, P Miralles, R A Silvestre, M L Villanueva, J Marc. Pancreastatin inhibits insulin secretion as induced by glucagon, vasoactive intestinal peptide, gastric inhibitory peptide, and 8-cholecystokinin in the perfused rat pancreas. Metabolism: clinical and experimental. vol 38. issue 7. 1989-08-10. PMID:2661967. |
to further explore the influence of pancreastatin on islet cell secretion, the effect of synthetic porcine pancreastatin (a 2-micrograms priming dose, followed by constant infusion at a concentration of 15.7 nmol/l) was studied on the insulin, glucagon, and somatostatin responses to 1 nmol/l vasoactive intestinal peptide (vip), 1 nmol/l gastric inhibitory peptide (gip), and 1 nmol/l 26 to 33 octapeptide form of cholecystokinin (8-cck). |
1989-08-10 |
2023-08-11 |
rat |
| E Peiró, P Miralles, R A Silvestre, M L Villanueva, J Marc. Pancreastatin inhibits insulin secretion as induced by glucagon, vasoactive intestinal peptide, gastric inhibitory peptide, and 8-cholecystokinin in the perfused rat pancreas. Metabolism: clinical and experimental. vol 38. issue 7. 1989-08-10. PMID:2661967. |
pancreastatin infusion consistently reduced the insulin responses to vip, gip, and 8-cck without modifying glucagon or somatostatin release. |
1989-08-10 |
2023-08-11 |
rat |
| P H Groo. The influence of body weight, age and glucose tolerance on the relationship between GIP secretion and beta-cell function in man. Scandinavian journal of clinical and laboratory investigation. vol 49. issue 4. 1989-08-10. PMID:2662384. |
the aim of the present study was to examine the association between insulin and gastric inhibitory polypetide (gip) secretion in conditions characterized by insulin resistance, i.e. |
1989-08-10 |
2023-08-11 |
human |
| N Inagaki, Y Seino, J Takeda, H Yano, Y Yamada, G I Bell, R L Eddy, Y Fukushima, M G Byers, T B Show. Gastric inhibitory polypeptide: structure and chromosomal localization of the human gene. Molecular endocrinology (Baltimore, Md.). vol 3. issue 6. 1989-08-09. PMID:2739653. |
gastric inhibitory polypeptide (gip) is a 42-amino-acid hormone which may have a role in the regulation of insulin secretion. |
1989-08-09 |
2023-08-11 |
human |
| E K Salminen, S J Salminen, L Porkka, P Kwasowski, V Marks, P E Koivistoine. Xylitol vs glucose: effect on the rate of gastric emptying and motilin, insulin, and gastric inhibitory polypeptide release. The American journal of clinical nutrition. vol 49. issue 6. 1989-07-13. PMID:2658536. |
the effect of xylitol and glucose on the rate of gastric emptying and intestinal transit and on motilin, gastric inhibitory polypeptide (gip), and insulin release were studied in human volunteers. |
1989-07-13 |
2023-08-11 |
human |
| E K Salminen, S J Salminen, L Porkka, P Kwasowski, V Marks, P E Koivistoine. Xylitol vs glucose: effect on the rate of gastric emptying and motilin, insulin, and gastric inhibitory polypeptide release. The American journal of clinical nutrition. vol 49. issue 6. 1989-07-13. PMID:2658536. |
similar dosing without the label was used in motilin, gip, and insulin studies. |
1989-07-13 |
2023-08-11 |
human |
| I R Jones, D R Owens, S D Luzio, T M Haye. Obesity is associated with increased post-prandial GIP levels which are not reduced by dietary restriction and weight loss. Diabete & metabolisme. vol 15. issue 1. 1989-07-10. PMID:2721810. |
following diet and weight-reduction there was a significant decrease in both fasting and post-prandial insulin levels in the obese subjects but there were no significant changes in glucose or gip concentrations. |
1989-07-10 |
2023-08-11 |
human |
| I R Jones, D R Owens, S D Luzio, T M Haye. Obesity is associated with increased post-prandial GIP levels which are not reduced by dietary restriction and weight loss. Diabete & metabolisme. vol 15. issue 1. 1989-07-10. PMID:2721810. |
the increased gip concentrations may contribute the observed hyperinsulinaemia in obesity, but its contribution is likely to be small in view of the decrease in insulin concentrations following diet and weight-loss which was independent of any change in gip. |
1989-07-10 |
2023-08-11 |
human |
| K C King, A Oliven, S C Kalha. Functional enteroinsular axis in full-term newborn infants. Pediatric research. vol 25. issue 5. 1989-06-12. PMID:2497435. |
plasma insulin and gip concentrations were compared. |
1989-06-12 |
2023-08-11 |
Not clear |
| K C King, A Oliven, S C Kalha. Functional enteroinsular axis in full-term newborn infants. Pediatric research. vol 25. issue 5. 1989-06-12. PMID:2497435. |
however, when glucose was infused orogastrically at a lower rate (8 mg/kg/min), plasma gip concentrations rose, but no enhancement of insulin response was detected, suggesting the importance of the role of circulating glucose in the "enteroinsular axis". |
1989-06-12 |
2023-08-11 |
Not clear |
| K C King, A Oliven, S C Kalha. Functional enteroinsular axis in full-term newborn infants. Pediatric research. vol 25. issue 5. 1989-06-12. PMID:2497435. |
the infants of diabetic mothers and the large-for-gestational-age infants had more rapid insulin response to orogastrically administered glucose, but their gip responses were similar to that of normal infants. |
1989-06-12 |
2023-08-11 |
Not clear |
| K C King, A Oliven, S C Kalha. Functional enteroinsular axis in full-term newborn infants. Pediatric research. vol 25. issue 5. 1989-06-12. PMID:2497435. |
the rising plasma gip contributed in part to the enhanced insulin response to enterally infused glucose. |
1989-06-12 |
2023-08-11 |
Not clear |
| N H Rubin, G Alinder, W J Rietveld, P L Rayford, J C Thompso. Restricted feeding schedules alter the circadian rhythms of serum insulin and gastric inhibitory polypeptide. Regulatory peptides. vol 23. issue 3. 1989-05-10. PMID:3070645. |
insulin and gastric inhibitory polypeptide (gip) have a circadian rhythm of secretion that is altered by various feeding schedules. |
1989-05-10 |
2023-08-11 |
rat |
| N H Rubin, G Alinder, W J Rietveld, P L Rayford, J C Thompso. Restricted feeding schedules alter the circadian rhythms of serum insulin and gastric inhibitory polypeptide. Regulatory peptides. vol 23. issue 3. 1989-05-10. PMID:3070645. |
when highest and lowest measured concentrations were compared in ad libitum fed rats, insulin more than doubled (445 +/- 50 to 993 +/- 180 pg/ml) and gip more than tripled (682 +/- 108 to 1964 +/- 145 pg/ml) during a 24-h period. |
1989-05-10 |
2023-08-11 |
rat |
| N H Rubin, G Alinder, W J Rietveld, P L Rayford, J C Thompso. Restricted feeding schedules alter the circadian rhythms of serum insulin and gastric inhibitory polypeptide. Regulatory peptides. vol 23. issue 3. 1989-05-10. PMID:3070645. |
circadian rhythms occurred for insulin with all feeding schedules and for gip with all schedules except fasted rats. |
1989-05-10 |
2023-08-11 |
rat |
| N H Rubin, G Alinder, W J Rietveld, P L Rayford, J C Thompso. Restricted feeding schedules alter the circadian rhythms of serum insulin and gastric inhibitory polypeptide. Regulatory peptides. vol 23. issue 3. 1989-05-10. PMID:3070645. |
this finding implies an endogenous insulin rhythm, whereas food intake controls gip secretion. |
1989-05-10 |
2023-08-11 |
rat |
| Y Tanaka, M Miyata, M Hamaji, M Izukura, M Nakamura, Y Kawashim. Role of gastric inhibitory polypeptide in altered glucose metabolism after removal of the jejunum in dogs. Surgery. vol 105. issue 4. 1989-05-08. PMID:2648629. |
significant decreases were simultaneously observed in the responses of both insulin and gip 1, 3, and 6 months after the surgery compared with the preoperative controls. |
1989-05-08 |
2023-08-11 |
Not clear |
| Y Tanaka, M Miyata, M Hamaji, M Izukura, M Nakamura, Y Kawashim. Role of gastric inhibitory polypeptide in altered glucose metabolism after removal of the jejunum in dogs. Surgery. vol 105. issue 4. 1989-05-08. PMID:2648629. |
these results indicate that the gip deficiency caused by removal of the jejunum may play a role in the poor insulin response to luminal stimuli, which contributes to glucose intolerance. |
1989-05-08 |
2023-08-11 |
Not clear |
| I R Jones, D R Owens, S Luzio, T M Haye. Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 21. issue 1. 1989-05-05. PMID:2647605. |
frequent plasma glucose, insulin, c-peptide and gip measurements were made throughout and the study was continued until 200 min. |
1989-05-05 |
2023-08-11 |
human |