| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C K Lardinois, R B Richeson, G H Starich, D Mazzu, E L Mazzaferr. Gastric inhibitory polypeptide mechanisms of augmenting insulin secretion. Life sciences. vol 47. issue 12. 1990-12-04. PMID:2122145. |
lpx inhibitors significantly (p less than 0.01) decreased glucose-dependent insulin secretion and this decrease persisted despite the addition of gip. |
1990-12-04 |
2023-08-11 |
rat |
| C K Lardinois, R B Richeson, G H Starich, D Mazzu, E L Mazzaferr. Gastric inhibitory polypeptide mechanisms of augmenting insulin secretion. Life sciences. vol 47. issue 12. 1990-12-04. PMID:2122145. |
simultaneous treatment of islet cell cultures with gip and co inhibitors yielded insulin responses that were indistinguishable from co inhibition alone. |
1990-12-04 |
2023-08-11 |
rat |
| S Suzuki, K Kawai, S Ohashi, H Mukai, Y Murayama, K Yamashit. Reduced insulinotropic effects of glucagonlike peptide I-(7-36)-amide and gastric inhibitory polypeptide in isolated perfused diabetic rat pancreas. Diabetes. vol 39. issue 11. 1990-12-04. PMID:2146178. |
we therefore examined the effects of glucagonlike peptide i-(7-36)-amide (truncated glp-i) and gastric inhibitory polypeptide (gip) on insulin and glucagon release from isolated perfused pancreases of diabetic rats (12-14 wk of age, mean +/- se fasting plasma glucose 8.9 +/- 0.6 mm, n = 25) after an injection of 90 mg/kg streptozocin on the 2nd day after birth and compared the results with those of nondiabetic control rats. |
1990-12-04 |
2023-08-11 |
rat |
| S Suzuki, K Kawai, S Ohashi, H Mukai, Y Murayama, K Yamashit. Reduced insulinotropic effects of glucagonlike peptide I-(7-36)-amide and gastric inhibitory polypeptide in isolated perfused diabetic rat pancreas. Diabetes. vol 39. issue 11. 1990-12-04. PMID:2146178. |
in diabetic rats, the infusion of 1 nm glp-i or gip in perfusates with varying glucose concentrations (2.8, 5.6, 8.3, 11.1, or 22.2 mm) caused a nearly equal degree of insulin stimulation from a similar basal insulin level. |
1990-12-04 |
2023-08-11 |
rat |
| L M Morgan, J A Tredger, J Wright, V Mark. The effect of soluble- and insoluble-fibre supplementation on post-prandial glucose tolerance, insulin and gastric inhibitory polypeptide secretion in healthy subjects. The British journal of nutrition. vol 64. issue 1. 1990-10-23. PMID:2169302. |
venous blood samples were taken before, and at intervals for 180 min following the meal, and analysed for insulin, gastric inhibitory polypeptide (gip) and paracetamol (as an index of gastric emptying). |
1990-10-23 |
2023-08-11 |
human |
| L M Morgan, J A Tredger, J Wright, V Mark. The effect of soluble- and insoluble-fibre supplementation on post-prandial glucose tolerance, insulin and gastric inhibitory polypeptide secretion in healthy subjects. The British journal of nutrition. vol 64. issue 1. 1990-10-23. PMID:2169302. |
the failure of sugar-beet fibre to reduce post-prandial insulin secretion despite improved glucose tolerance may be due to the observed increased secretion of gip. |
1990-10-23 |
2023-08-11 |
human |
| L M Morgan, J A Tredger, J Wright, V Mark. The effect of soluble- and insoluble-fibre supplementation on post-prandial glucose tolerance, insulin and gastric inhibitory polypeptide secretion in healthy subjects. The British journal of nutrition. vol 64. issue 1. 1990-10-23. PMID:2169302. |
the increased insulin levels seen following soya-bean-cotyledon fibre supplementation cannot be attributed either to changes in glucose tolerance, gip secretion or gastric emptying. |
1990-10-23 |
2023-08-11 |
human |
| C J Bailey, L C Wilkes, J M Conlon, P H Armstrong, K D Buchana. Effects of gastric inhibitory polypeptide, vasoactive intestinal polypeptide and peptide histidine isoleucine on the secretion of hormones by isolated mouse pancreatic islets. The Journal of endocrinology. vol 125. issue 3. 1990-08-28. PMID:1973701. |
the release of insulin, glucagon, somatostatin and pancreatic polypeptide (pp) by isolated mouse pancreatic islets was determined during 30-min incubations at 5.6 and 16.7 mmol glucose/l in the absence and presence of gastric inhibitory polypeptide (gip), vasoactive intestinal polypeptide (vip) and peptide histidine isoleucine (phi) at concentrations of 1-1000 nmol/l. |
1990-08-28 |
2023-08-11 |
mouse |
| C J Bailey, L C Wilkes, J M Conlon, P H Armstrong, K D Buchana. Effects of gastric inhibitory polypeptide, vasoactive intestinal polypeptide and peptide histidine isoleucine on the secretion of hormones by isolated mouse pancreatic islets. The Journal of endocrinology. vol 125. issue 3. 1990-08-28. PMID:1973701. |
insulin release was enhanced (greater than 50%) by gip (100-1000 nmol/l) and vip (1 mumol/l) at 5.6 mmol glucose/l, but not at 16.7 mmol glucose/l. |
1990-08-28 |
2023-08-11 |
mouse |
| F C Brunicardi, P Druck, N E Seymour, Y S Sun, D Elahi, D K Anderse. Selective neurohormonal interactions in islet cell secretion in the isolated perfused human pancreas. The Journal of surgical research. vol 48. issue 4. 1990-06-21. PMID:1971030. |
to investigate the effects of stimulant interactions on alpha- and beta-cell secretions, the differential effects of gastric inhibitory polypeptide (gip) and cholinergic stimulation (cs) on insulin (iri) and glucagon (irg) release were examined during euglycemic, single-pass perfusion in the isolated human pancreas. |
1990-06-21 |
2023-08-11 |
human |
| M Fried, E A Mayer, S R Bloom, I L Taylor, J H Meye. GIP and insulin release in relation to gastric emptying of a mixed meal in man. Regulatory peptides. vol 26. issue 3. 1990-03-26. PMID:2695982. |
gip and insulin release in relation to gastric emptying of a mixed meal in man. |
1990-03-26 |
2023-08-11 |
human |
| M Fried, E A Mayer, S R Bloom, I L Taylor, J H Meye. GIP and insulin release in relation to gastric emptying of a mixed meal in man. Regulatory peptides. vol 26. issue 3. 1990-03-26. PMID:2695982. |
to clarify the role of gip (gastric inhibitory polypeptide) as an incretin, we related temporally the gastric emptying of fat, protein and glucose to plasma levels of glucose, gip and insulin in man. |
1990-03-26 |
2023-08-11 |
human |
| M Fried, E A Mayer, S R Bloom, I L Taylor, J H Meye. GIP and insulin release in relation to gastric emptying of a mixed meal in man. Regulatory peptides. vol 26. issue 3. 1990-03-26. PMID:2695982. |
by contrast, plasma gip rose more slowly than insulin, from a basal value of 9.4 pm, and remained elevated, in the range of 14-18 pm, throughout the 240 min observation period. |
1990-03-26 |
2023-08-11 |
human |
| J D Clark, T Wheatley, I G Brons, S R Bloom, R Y Caln. Studies of the entero-insular axis following pancreas transplantation in man: neural or hormonal control? Diabetic medicine : a journal of the British Diabetic Association. vol 6. issue 9. 1990-03-06. PMID:2533043. |
to study the role of hormonal and neural factors in the control of the entero-insular axis the insulin, c-peptide, and glucose-dependent insulinotropic peptide (gip) responses to oral and intravenous glucose were investigated in 5 patients who had received a combined kidney and paratopic pancreas transplant, with physiological portal venous drainage. |
1990-03-06 |
2023-08-11 |
human |
| J D Clark, T Wheatley, I G Brons, S R Bloom, R Y Caln. Studies of the entero-insular axis following pancreas transplantation in man: neural or hormonal control? Diabetic medicine : a journal of the British Diabetic Association. vol 6. issue 9. 1990-03-06. PMID:2533043. |
the incretin effects for insulin (patients 4.4 +/- 1.4, control subjects 7.7 +/- 1.8) and c-peptide (patients 4.4 +/- 0.9, control subjects 3.7 +/- 0.9) and the gip responses to oral and intravenous glucose were not significantly different between transplant patients and control subjects. |
1990-03-06 |
2023-08-11 |
human |
| I R Jones, D R Owens, J Vora, S D Luzio, T M Haye. A supplementary infusion of glucose-dependent insulinotropic polypeptide (GIP) with a meal does not significantly improve the beta cell response or glucose tolerance in type 2 diabetes mellitus. Diabetes research and clinical practice. vol 7. issue 4. 1990-03-01. PMID:2693029. |
frequent measurements of plasma glucose, c-peptide, insulin and gip concentrations were made. |
1990-03-01 |
2023-08-11 |
Not clear |
| Z Tulassay, T Tulassay, R Gupta, G Ciern. Long acting somatostatin analogue in dumping syndrome. The British journal of surgery. vol 76. issue 12. 1990-02-22. PMID:2691013. |
in these patients significant elevations (p less than 0.001) in the insulin level (from 10 (0.9) to 40 (9.1) microe/ml) and gastric inhibitory peptide (gip) concentration (from 100 (13) to 220 (41) ng/l) were seen, compared with the initial values. |
1990-02-22 |
2023-08-11 |
Not clear |
| Z Tulassay, T Tulassay, R Gupta, G Ciern. Long acting somatostatin analogue in dumping syndrome. The British journal of surgery. vol 76. issue 12. 1990-02-22. PMID:2691013. |
during the application of sms 201-995 hypoglycaemia did not develop and plasma insulin and gip concentrations remained unchanged. |
1990-02-22 |
2023-08-11 |
Not clear |
| b' A R Baer, J Dupr\\xc3\\xa. Suppression of insulin receptor binding by prolonged enteral or parenteral nutrient infusion in the rat: role of gastric inhibitory polypeptide. Canadian journal of physiology and pharmacology. vol 67. issue 9. 1990-02-08. PMID:2513110.' |
supplementing the parenteral infusate with porcine gastric inhibitory polypeptide (gip) to approximate plasma immunoreactive gip levels achieved with enteral feeding further increases steady-state plasma insulin and glucose concentrations, suggesting insulin resistance. |
1990-02-08 |
2023-08-11 |
rat |
| b' A R Baer, J Dupr\\xc3\\xa. Suppression of insulin receptor binding by prolonged enteral or parenteral nutrient infusion in the rat: role of gastric inhibitory polypeptide. Canadian journal of physiology and pharmacology. vol 67. issue 9. 1990-02-08. PMID:2513110.' |
we examined the effects of sustained hyperinsulinemia elicited by continuous nutrient infusion on insulin binding to isolated rat adipocytes and the modification of this response by gip. |
1990-02-08 |
2023-08-11 |
rat |