| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Oben, L Morgan, J Fletcher, V Mark. Effect of the entero-pancreatic hormones, gastric inhibitory polypeptide and glucagon-like polypeptide-1(7-36) amide, on fatty acid synthesis in explants of rat adipose tissue. The Journal of endocrinology. vol 130. issue 2. 1991-11-01. PMID:1919397. |
insulin and gip caused a significantly greater stimulation of [14c]acetate incorporation into fatty acids in omental adipose tissue than in either epididymal or subcutaneous adipose tissue. |
1991-11-01 |
2023-08-11 |
rat |
| J Oben, L Morgan, J Fletcher, V Mark. Effect of the entero-pancreatic hormones, gastric inhibitory polypeptide and glucagon-like polypeptide-1(7-36) amide, on fatty acid synthesis in explants of rat adipose tissue. The Journal of endocrinology. vol 130. issue 2. 1991-11-01. PMID:1919397. |
the study indicates that gip and glp-1(7-36)amide, in addition to stimulating insulin secretion, may play a direct physiological role in vivo, in common with insulin, in promoting fatty acid synthesis in adipose tissue. |
1991-11-01 |
2023-08-11 |
rat |
| R A Pederson, R V Campos, A M Buchan, C B Chisholm, J C Russell, J C Brow. Comparison of the enteroinsular axis in two strains of obese rat, the fatty Zucker and the JCR:LA-corpulent. International journal of obesity. vol 15. issue 7. 1991-10-23. PMID:1894423. |
it has been hypothesized that an abnormal enteroinsular axis leading to hypersecretion of the insulin releasing hormone gastric inhibitory polypeptide (gip) could contribute to the hyperinsulinemia of obesity, although this has been controversial. |
1991-10-23 |
2023-08-11 |
rat |
| R A Pederson, R V Campos, A M Buchan, C B Chisholm, J C Russell, J C Brow. Comparison of the enteroinsular axis in two strains of obese rat, the fatty Zucker and the JCR:LA-corpulent. International journal of obesity. vol 15. issue 7. 1991-10-23. PMID:1894423. |
the in vivo gip and insulin responses to an oral glucose challenge, as well as glucose tolerance, were compared in lean and obese phenotypes of both strains as well as the sensitivity of the perfused pancreas to the secretagogues glucose, arginine and gip. |
1991-10-23 |
2023-08-11 |
rat |
| E Renard, C Parer-Richard, J L Richard, S Jureidini, A Orsetti, J Mirouz. Effect of Miglitol (Bay m1099), a new alpha-glucosidase inhibitor, on glucose, insulin, C-peptide and GIP responses to an oral sucrose load in patients with post-prandial hypoglycaemic symptoms. Diabete & metabolisme. vol 17. issue 3. 1991-10-07. PMID:1884880. |
effect of miglitol (bay m1099), a new alpha-glucosidase inhibitor, on glucose, insulin, c-peptide and gip responses to an oral sucrose load in patients with post-prandial hypoglycaemic symptoms. |
1991-10-07 |
2023-08-11 |
Not clear |
| E Renard, C Parer-Richard, J L Richard, S Jureidini, A Orsetti, J Mirouz. Effect of Miglitol (Bay m1099), a new alpha-glucosidase inhibitor, on glucose, insulin, C-peptide and GIP responses to an oral sucrose load in patients with post-prandial hypoglycaemic symptoms. Diabete & metabolisme. vol 17. issue 3. 1991-10-07. PMID:1884880. |
during four hours, plasma glucose levels were continuously monitored and plasma insulin and gastric inhibitory polypeptide (gip) levels were measured at 30-minute intervals; serum c-peptide concentration was determined at 0, 30, 60 minutes and then every hour. |
1991-10-07 |
2023-08-11 |
Not clear |
| E Renard, C Parer-Richard, J L Richard, S Jureidini, A Orsetti, J Mirouz. Effect of Miglitol (Bay m1099), a new alpha-glucosidase inhibitor, on glucose, insulin, C-peptide and GIP responses to an oral sucrose load in patients with post-prandial hypoglycaemic symptoms. Diabete & metabolisme. vol 17. issue 3. 1991-10-07. PMID:1884880. |
blunting the insulin response to glucose directly by delaying glucose absorption and indirectly through reducing gip secretion, may be a valuable therapeutic approach in reactive hypoglycemia; nevertheless, long-term study with miglitol are needed, due to the poor intestinal tolerance of this drug in the present acute study. |
1991-10-07 |
2023-08-11 |
Not clear |
| R S Hurley, B M Bossetti, T M O'Dorisio, E B Tenison, M A Welch, R R Ric. The effect of exercise training on body weight and peptide hormone patterns in normal weight college-age men. The Journal of sports medicine and physical fitness. vol 31. issue 1. 1991-09-05. PMID:1861484. |
resting and peak glucose, insulin, glucagon, gastric inhibitory polypeptide (gip) and pancreatic polypeptide (pp) levels were evaluated pretraining, 3 weeks and 10 weeks posttraining in seven college age males. |
1991-09-05 |
2023-08-11 |
Not clear |
| R S Hurley, B M Bossetti, T M O'Dorisio, E B Tenison, M A Welch, R R Ric. The effect of exercise training on body weight and peptide hormone patterns in normal weight college-age men. The Journal of sports medicine and physical fitness. vol 31. issue 1. 1991-09-05. PMID:1861484. |
although gip did not change significantly with training, an uncoupling of gip and insulin peak responses was observed. |
1991-09-05 |
2023-08-11 |
Not clear |
| J Ishizuka, K Tatemoto, D V Cohn, J C Thompson, G H Greele. Effects of pancreastatin and chromogranin A on insulin release stimulated by various insulinotropic agents. Regulatory peptides. vol 34. issue 1. 1991-08-27. PMID:1857778. |
the effects of porcine pancreastatin on insulin release stimulated by insulinotropic agents, glucagon, cholecystokinin-octapeptide (cck-8), gastric inhibitory polypeptide (gip) and l-arginine, were compared to those of bovine chromogranin a (cga) using the isolated perfused rat pancreas. |
1991-08-27 |
2023-08-11 |
rat |
| J Ishizuka, K Tatemoto, D V Cohn, J C Thompson, G H Greele. Effects of pancreastatin and chromogranin A on insulin release stimulated by various insulinotropic agents. Regulatory peptides. vol 34. issue 1. 1991-08-27. PMID:1857778. |
similarly, cga did not affect insulin release stimulated by cck-8 or gip. |
1991-08-27 |
2023-08-11 |
rat |
| P R Flatt, P Kwasowski, R J Howland, C J Baile. Gastric inhibitory polypeptide and insulin responses to orally administered amino acids in genetically obese hyperglycemic (ob/ob) mice. The Journal of nutrition. vol 121. issue 7. 1991-07-25. PMID:2051232. |
the effects of oral administration of eight l-amino acids (alanine, arginine, cysteine, glycine, histidine, hydroxyproline, lysine and threonine) individually or as an amino acid mixture on plasma gastric inhibitory polypeptide (gip), insulin and glucose concentrations were examined in 18-h fasted obese hyperglycemic (ob/ob) mice. |
1991-07-25 |
2023-08-11 |
mouse |
| P R Flatt, P Kwasowski, R J Howland, C J Baile. Gastric inhibitory polypeptide and insulin responses to orally administered amino acids in genetically obese hyperglycemic (ob/ob) mice. The Journal of nutrition. vol 121. issue 7. 1991-07-25. PMID:2051232. |
at a dose of 5.4 mmol/kg body weight, arginine, cysteine, histidine and the amino acid mixture were equipotent in terms of increasing plasma gip and insulin concentrations. |
1991-07-25 |
2023-08-11 |
mouse |
| P R Flatt, P Kwasowski, R J Howland, C J Baile. Gastric inhibitory polypeptide and insulin responses to orally administered amino acids in genetically obese hyperglycemic (ob/ob) mice. The Journal of nutrition. vol 121. issue 7. 1991-07-25. PMID:2051232. |
alanine, hydroxyproline and lysine also increased plasma gip, but insulin concentrations were unchanged. |
1991-07-25 |
2023-08-11 |
mouse |
| P R Flatt, P Kwasowski, R J Howland, C J Baile. Gastric inhibitory polypeptide and insulin responses to orally administered amino acids in genetically obese hyperglycemic (ob/ob) mice. The Journal of nutrition. vol 121. issue 7. 1991-07-25. PMID:2051232. |
in contrast, threonine failed to affect either gip or insulin concentrations. |
1991-07-25 |
2023-08-11 |
mouse |
| P R Flatt, P Kwasowski, R J Howland, C J Baile. Gastric inhibitory polypeptide and insulin responses to orally administered amino acids in genetically obese hyperglycemic (ob/ob) mice. The Journal of nutrition. vol 121. issue 7. 1991-07-25. PMID:2051232. |
there was no correlation between either the incremental or integrated gip and insulin responses, and none of the amino acids administered affected circulating glucose concentrations. |
1991-07-25 |
2023-08-11 |
mouse |
| P R Flatt, P Kwasowski, R J Howland, C J Baile. Gastric inhibitory polypeptide and insulin responses to orally administered amino acids in genetically obese hyperglycemic (ob/ob) mice. The Journal of nutrition. vol 121. issue 7. 1991-07-25. PMID:2051232. |
however, gip made only a modest contribution to the stimulation of insulin secretion following administration of amino acids in the presence of basal glycemia. |
1991-07-25 |
2023-08-11 |
mouse |
| P R Flatt, C J Bailey, P Kwasowski, S K Swanston-Flat. Effects of diets rich in sucrose, coconut fat and safflowerseed oil on the development of the obese hyperglycaemic (ob/ob) syndrome in mice. Diabetes research (Edinburgh, Scotland). vol 13. issue 1. 1991-07-24. PMID:2097092. |
with the exception of insulin sensitivity which was enhanced with safflowerseed oil, plasma concentrations of glucose and gastric inhibitory polypeptide (gip), glucose tolerance, intestinal gip content and the gip response to oral fat were similar. |
1991-07-24 |
2023-08-11 |
mouse |
| E Heinze, J Schlickenrieder, R W Holl, R Eber. Reduced secretion of gastric inhibitory polypeptide in Turner patients with impaired glucose tolerance. European journal of pediatrics. vol 150. issue 5. 1991-07-17. PMID:2044607. |
oral glucose tolerance tests were performed in 12 turner patients with simultaneous determination of plasma glucose, insulin and gip. |
1991-07-17 |
2023-08-11 |
Not clear |
| H C Fehmann, J F Habene. Homologous desensitization of the insulinotropic glucagon-like peptide-I (7-37) receptor on insulinoma (HIT-T15) cells. Endocrinology. vol 128. issue 6. 1991-07-02. PMID:1645253. |
preperifusion of hit-t15 cells with 100 nmol/liter glucagon (10 min) or 100 nmol/liter gastric inhibitory peptide (gip) (10 min) had no effect on the insulin secretory response to 10 nmol/liter glp-(7-37). |
1991-07-02 |
2023-08-11 |
human |