| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I R Jones, D R Owens, S Luzio, T M Haye. Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 21. issue 1. 1989-05-05. PMID:2647605. |
during the gip infusion there was an early significant rise in insulin concentration from 0.058 +/- 0.006 nmol/l to 0.106 +/- 0.007 nmol/l (p less than 0.01) within 6 min of commencing the gip infusion and insulin levels reached a peak of 0.131 +/- 0.011 nmol/l at 10 min (p less than 0.01). |
1989-05-05 |
2023-08-11 |
human |
| I R Jones, D R Owens, S Luzio, T M Haye. Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 21. issue 1. 1989-05-05. PMID:2647605. |
insulin levels remained significantly elevated during the rest of the gip infusion (p less than 0.01-0.001) and returned to basal values 20 min post infusion. |
1989-05-05 |
2023-08-11 |
human |
| R J Heine, I Hanning, L Morgan, K G Albert. The oral glucose tolerance test (OGTT): effect of rate of ingestion of carbohydrate and different carbohydrate preparations. Diabetes care. vol 6. issue 5. 1989-03-27. PMID:6400703. |
in this study the effect on blood glucose, serum insulin, c-peptide, and plasma gastric inhibitory polypeptide (gip) of giving 75 g glucose in 300 ml over 1 and 10 min (g1 and g10) was investigated in six subjects. |
1989-03-27 |
2023-08-12 |
human |
| Y S Guo, P Singh, E Draviam, G H Greeley, J C Thompso. Peptide YY inhibits the insulinotropic action of gastric inhibitory polypeptide. Gastroenterology. vol 96. issue 3. 1989-03-23. PMID:2644149. |
the purpose of this investigation was to examine the effect of pyy on gastric inhibitory polypeptide (gip)-stimulated insulin release in conscious dogs with gastric and duodenal fistulas. |
1989-03-23 |
2023-08-11 |
Not clear |
| Y S Guo, P Singh, E Draviam, G H Greeley, J C Thompso. Peptide YY inhibits the insulinotropic action of gastric inhibitory polypeptide. Gastroenterology. vol 96. issue 3. 1989-03-23. PMID:2644149. |
in control experiments, 6 dogs received gip (400 pmol/kg, i.v., for 1 h) and glucose (0.6 g/kg, i.v., for 1 h); the integrated insulin response over a 1-h period was 142 +/- 32.7 ng-60 min/ml. |
1989-03-23 |
2023-08-11 |
Not clear |
| Y S Guo, P Singh, E Draviam, G H Greeley, J C Thompso. Peptide YY inhibits the insulinotropic action of gastric inhibitory polypeptide. Gastroenterology. vol 96. issue 3. 1989-03-23. PMID:2644149. |
intravenous infusion of three different doses of pyy (100, 200, or 400 pmol/kg.h) caused a significant inhibition of insulin release stimulated by gip + glucose; the integrated insulin response was reduced to 105, 88, and 79 ng-60 min/ml, respectively. |
1989-03-23 |
2023-08-11 |
Not clear |
| G M Reaven, A L Swislocki, C Y Jeng, C B Hollenbeck, K Schwartz, Y D Che. Effect of enprostil on plasma glucose, insulin and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 10. 1989-03-22. PMID:3146538. |
there was no change in either fasting or postprandial insulin concentration, but the postprandial gip response was also significantly reduced (p less than 0.001). |
1989-03-22 |
2023-08-11 |
Not clear |
| K E Schwartz, B Zaro, J Reynolds, J Duffy, T Saito, J S Hunt, H Seveliu. Suppression of postprandial glucose, insulin, C-peptide, and glucose-dependent insulinotropic peptide (GIP) in man by oral administration of a prostaglandin analogue (enprostil). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 10. 1989-03-22. PMID:3146539. |
suppression of postprandial glucose, insulin, c-peptide, and glucose-dependent insulinotropic peptide (gip) in man by oral administration of a prostaglandin analogue (enprostil). |
1989-03-22 |
2023-08-11 |
human |
| K E Schwartz, B Zaro, J Reynolds, J Duffy, T Saito, J S Hunt, H Seveliu. Suppression of postprandial glucose, insulin, C-peptide, and glucose-dependent insulinotropic peptide (GIP) in man by oral administration of a prostaglandin analogue (enprostil). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 10. 1989-03-22. PMID:3146539. |
mean overall peak levels for insulin, c-peptide, and glucose-dependent insulinotropic peptide (gip) were significantly suppressed by 36%, 16% and 60%, respectively by enprostil when compared to placebo. |
1989-03-22 |
2023-08-11 |
human |
| K E Schwartz, B Zaro, J Reynolds, J Duffy, T Saito, J S Hunt, H Seveliu. Suppression of postprandial glucose, insulin, C-peptide, and glucose-dependent insulinotropic peptide (GIP) in man by oral administration of a prostaglandin analogue (enprostil). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 10. 1989-03-22. PMID:3146539. |
the overall integrated postprandial responses for insulin, c-peptide, and gip were significantly reduced by 42%, 39% and 90%, respectively while that for glucose above baseline was reduced by 44% (p = 0.098). |
1989-03-22 |
2023-08-11 |
human |
| N Holst, T G Jenssen, P G Burhol, R Jord. Gastrointestinal regulatory peptides during oxytocin infusion in post-term pregnancies. Acta physiologica Scandinavica. vol 132. issue 1. 1989-03-21. PMID:2906209. |
the plasma concentrations of the gastrointestinal regulatory peptides vasoactive intestinal polypeptide (vip), insulin, secretin, somatostatin, motilin, pancreatic polypeptide (pp) and gastric inhibitory polypeptide (gip), as well as blood glucose, were measured in eight healthy women before, during and after oxytocin infusion in post-term pregnancies. |
1989-03-21 |
2023-08-11 |
Not clear |
| N Holst, T G Jenssen, P G Burhol, R Jord. Gastrointestinal regulatory peptides during oxytocin infusion in post-term pregnancies. Acta physiologica Scandinavica. vol 132. issue 1. 1989-03-21. PMID:2906209. |
no changes were found for plasma insulin, gip and blood glucose. |
1989-03-21 |
2023-08-11 |
Not clear |
| J J Altman, A Penfornis, J Boillot, M Malett. Bioartificial pancreas in autoimmune nonobese diabetic mice. ASAIO transactions. vol 34. issue 3. 1989-01-26. PMID:2848560. |
electron microscopy (rectangular crystalline nucleoids characteristic of b-cells), in vitro release of insulin (during abrupt changes in glucose concentration from 40 to 400 mg/dl and return, m +/- sd insulin levels were 122 +/- 5 uu/ml and 315 +/- 17 at low and high glucose), evidence of binding hormone receptors (vip and gip, the binding sites being coupled with adenylyl cyclase stimulation) were used to assess the quality of the transplant. |
1989-01-26 |
2023-08-11 |
mouse |
| P R Holt, D Thea, M Y Yang, D P Kotle. Intestinal and metabolic responses to an alpha-glucosidase inhibitor in normal volunteers. Metabolism: clinical and experimental. vol 37. issue 12. 1989-01-09. PMID:3057329. |
fasting and postprandial concentrations of glucose, insulin, glucagon, enteroglucagon, and gastrointestinal inhibitory peptide (gip) were measured after the first and last dose of bay 1099, and the fecal excretions of protein, fat, fiber, and total calories were measured on the last three days of each diet. |
1989-01-09 |
2023-08-11 |
human |
| P R Holt, D Thea, M Y Yang, D P Kotle. Intestinal and metabolic responses to an alpha-glucosidase inhibitor in normal volunteers. Metabolism: clinical and experimental. vol 37. issue 12. 1989-01-09. PMID:3057329. |
increasing doses of bay 1099 were found to decrease the postprandial rise in serum glucose concentration, delay the time to peak insulin concentration, and decrease the output of gip after the meal. |
1989-01-09 |
2023-08-11 |
human |
| U R Fölsch, M Fussek, R Ebert, W Creutzfeld. Endocrine pancreatic function during atrophy of the exocrine gland. Pancreas. vol 3. issue 5. 1988-12-22. PMID:3054869. |
serum levels of glucose, insulin, and gastric inhibitory polypeptide (gip) in response to intraduodenal and intravenous glucose loads have been examined in rats with exocrine pancreatic atrophy induced by feeding them a copper-deficient diet supplemented with d-penicillamine for 10-12 weeks. |
1988-12-22 |
2023-08-11 |
rat |
| B Amiranoff, A M Lorinet, I Lagny-Pourmir, M Laburth. Mechanism of galanin-inhibited insulin release. Occurrence of a pertussis-toxin-sensitive inhibition of adenylate cyclase. European journal of biochemistry. vol 177. issue 1. 1988-12-16. PMID:2460348. |
in the insulin-secreting beta cell line rin m 5f, galanin, a newly discovered ubiquitous neuropeptide, inhibited, by 50%, the stimulation of insulin release induced by gastric inhibitory polypeptide (gip) or forskolin, i.e. |
1988-12-16 |
2023-08-11 |
Not clear |
| M Imamura, I Sasaki, Y Funayama, Y Kamiyama, T Sat. [Pathophysiology following biliary reconstruction procedures, with special reference to gastric acid secretion, peptic ulcer, metabolism of carbohydrate and fat, and gastrointestinal hormone release]. Nihon Geka Gakkai zasshi. vol 89. issue 8. 1988-11-30. PMID:3185485. |
fasting concentrations of gut hormones (gastrin, gip, insulin and gli) were similar to those before surgery, and increased after the ingestion of the test meals. |
1988-11-30 |
2023-08-11 |
Not clear |
| M Imamura, I Sasaki, Y Funayama, Y Kamiyama, T Sat. [Pathophysiology following biliary reconstruction procedures, with special reference to gastric acid secretion, peptic ulcer, metabolism of carbohydrate and fat, and gastrointestinal hormone release]. Nihon Geka Gakkai zasshi. vol 89. issue 8. 1988-11-30. PMID:3185485. |
gastrin and total gli levels tended to be higher in the roux-y than in the interposition group, and vice versa for both insulin and gip. |
1988-11-30 |
2023-08-11 |
Not clear |
| K Shima, M Hirota, C Ohbosh. Effect of glucagon-like peptide-1 on insulin secretion. Regulatory peptides. vol 22. issue 3. 1988-11-15. PMID:3051138. |
comparable effects of gip and glp-1-(1-37) on insulin secretion were observed at concentrations of 1.0 nm and 10.0 nm, respectively. |
1988-11-15 |
2023-08-11 |
rat |