| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L R Roust, M Stesin, V L Go, P C O'Brien, R A Rizza, F J Servic. Role of gastric inhibitory polypeptide in postprandial hyperinsulinemia of obesity. The American journal of physiology. vol 254. issue 6 Pt 1. 1988-07-08. PMID:3287953. |
we conclude that 1) although postprandial plasma gip concentrations are normal, gip secretion is increased in obesity, 2) the postprandial hyperinsulinemia of obesity is not due to excessive insulin secretion but is likely secondary to altered insulin clearance, and 3) gip cannot account for the hyperinsulinemia of obesity through its insulinotropic action. |
1988-07-08 |
2023-08-11 |
human |
| B Beck, J P Ma. The effects of gastric inhibitory polypeptide and insulin on fatty acid uptake in adipose tissue are not mediated through cyclic AMP in lean and obese Zucker rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 1. 1988-07-06. PMID:2836284. |
to determine the mechanism by which gastric inhibitory polypeptide (gip) and insulin stimulate the in vitro fatty acid incorporation into adipose tissue (fiat), we measured the cyclic amp variations and fiat in epididymal fat pads of lean fa/-- and obese fa/fa zucker rats. |
1988-07-06 |
2023-08-11 |
rat |
| B Beck, J P Ma. The effects of gastric inhibitory polypeptide and insulin on fatty acid uptake in adipose tissue are not mediated through cyclic AMP in lean and obese Zucker rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 1. 1988-07-06. PMID:2836284. |
gip was used at 1, 2 and 4 ng/ml and insulin at a concentration of 100 microu/ml. |
1988-07-06 |
2023-08-11 |
rat |
| B Beck, J P Ma. The effects of gastric inhibitory polypeptide and insulin on fatty acid uptake in adipose tissue are not mediated through cyclic AMP in lean and obese Zucker rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 1. 1988-07-06. PMID:2836284. |
there was no significant variation of camp when fiat was stimulated either by gip, either by insulin or by both hormones. |
1988-07-06 |
2023-08-11 |
rat |
| B Beck, J P Ma. The effects of gastric inhibitory polypeptide and insulin on fatty acid uptake in adipose tissue are not mediated through cyclic AMP in lean and obese Zucker rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 1. 1988-07-06. PMID:2836284. |
we conclude that gip and insulin act through camp independent mechanisms in adipose tissue. |
1988-07-06 |
2023-08-11 |
rat |
| B Beck, J P Ma. The effects of gastric inhibitory polypeptide and insulin on fatty acid uptake in adipose tissue are not mediated through cyclic AMP in lean and obese Zucker rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 1. 1988-07-06. PMID:2836284. |
the modification by gip of insulin binding to adipocytes or an easier passage of fatty acids through the membrane could constitute alternative solutions for such mechanisms. |
1988-07-06 |
2023-08-11 |
rat |
| L T Ho, H F Pu, W J Sheu, W C Wang, P S Wan. Inhibition of somatostatin on glucose-induced release of gastric inhibitory polypeptide in rats. The Chinese journal of physiology. vol 30. issue 2. 1988-06-16. PMID:2896583. |
the effect of somatostatin on glucoseinduced secretion of insulin and gastric inhibitory polypeptide (gip) in rats was examined. |
1988-06-16 |
2023-08-11 |
rat |
| L T Ho, H F Pu, W J Sheu, W C Wang, P S Wan. Inhibition of somatostatin on glucose-induced release of gastric inhibitory polypeptide in rats. The Chinese journal of physiology. vol 30. issue 2. 1988-06-16. PMID:2896583. |
concentrations of gip and insulin in rat plasma samples were measured by radioimmunoassay. |
1988-06-16 |
2023-08-11 |
rat |
| L T Ho, H F Pu, W J Sheu, W C Wang, P S Wan. Inhibition of somatostatin on glucose-induced release of gastric inhibitory polypeptide in rats. The Chinese journal of physiology. vol 30. issue 2. 1988-06-16. PMID:2896583. |
the results revealed that the rise of plasma insulin and gip after the glucose load was abolished by a preinjection of somatostatin. |
1988-06-16 |
2023-08-11 |
rat |
| L T Ho, H F Pu, W J Sheu, W C Wang, P S Wan. Inhibition of somatostatin on glucose-induced release of gastric inhibitory polypeptide in rats. The Chinese journal of physiology. vol 30. issue 2. 1988-06-16. PMID:2896583. |
it is concluded that somatostatin at 10 micrograms inhibits the effects of oral glucose in stimulating the secretion of gip from the gut, and insulin from the pancreas in normal fasted rats. |
1988-06-16 |
2023-08-11 |
rat |
| B Beck, J P Max, C Villaum. Effects of somatostatin on the insulin- and gastric inhibitory polypeptide-stimulated fatty acid esterification in rat adipose tissue. International journal of obesity. vol 12. issue 1. 1988-05-31. PMID:2896178. |
relations exist between insulin, somatostatin (s) and gastric inhibitory polypeptide (gip) for the reciprocal control of their secretion but also for their role in lipid metabolism. |
1988-05-31 |
2023-08-11 |
rat |
| B Beck, J P Max, C Villaum. Effects of somatostatin on the insulin- and gastric inhibitory polypeptide-stimulated fatty acid esterification in rat adipose tissue. International journal of obesity. vol 12. issue 1. 1988-05-31. PMID:2896178. |
in the present experiment, we studied the effects of somatostatin on fatty acid incorporation into epididymal adipose tissue (fiat) of wistar rats when it was stimulated by insulin and gip. |
1988-05-31 |
2023-08-11 |
rat |
| B Beck, J P Max, C Villaum. Effects of somatostatin on the insulin- and gastric inhibitory polypeptide-stimulated fatty acid esterification in rat adipose tissue. International journal of obesity. vol 12. issue 1. 1988-05-31. PMID:2896178. |
cyclic somatostatin-14 was used at physiological (s1 : 50 pg/ml, s2 : 200 pg/ml) and supraphysiological (s3 : 666 pg/ml) concentrations whereas insulin and gip were used at postprandial levels (100 microu/ml and 2 ng/ml respectively). |
1988-05-31 |
2023-08-11 |
rat |
| B Beck, J P Max, C Villaum. Effects of somatostatin on the insulin- and gastric inhibitory polypeptide-stimulated fatty acid esterification in rat adipose tissue. International journal of obesity. vol 12. issue 1. 1988-05-31. PMID:2896178. |
on the contrary, when somatostatin was added with gip and insulin, fiat decreased to 102.3 +/- 2.5 per cent for s1 (p less than 0.01) and to 98.2 +/- 2.6 per cent for s3 (p less than 0.001). |
1988-05-31 |
2023-08-11 |
rat |
| B Beck, J P Max, C Villaum. Effects of somatostatin on the insulin- and gastric inhibitory polypeptide-stimulated fatty acid esterification in rat adipose tissue. International journal of obesity. vol 12. issue 1. 1988-05-31. PMID:2896178. |
these results indicate that somatostatin totally inhibits the fatty acid esterification induced by insulin and in the same proportions that induced by insulin associated with gip. |
1988-05-31 |
2023-08-11 |
rat |
| C K Lardinois, G H Starich, E L Mazzaferri, A DeLet. Effect of source of dietary fats on serum glucose, insulin, and gastric inhibitory polypeptide responses to mixed test meals in subjects with non-insulin dependent diabetes mellitus. Journal of the American College of Nutrition. vol 7. issue 2. 1988-05-31. PMID:3283195. |
to determine if a similar phenomenon occurs in subjects with non-insulin dependent diabetes mellitus (niddm), serum glucose, insulin, c-peptide, and gastric inhibitory polypeptide (gip) responses to three mixed test meals of varying fatty acid composition were assessed in twelve subjects with niddm. |
1988-05-31 |
2023-08-11 |
human |
| J Ishizuka, P Singh, G H Greeley, C M Townsend, C W Cooper, K Tatemoto, J C Thompso. A comparison of the insulinotropic and the insulin-inhibitory actions of gut peptides on newborn and adult rat islet cells. Pancreas. vol 3. issue 1. 1988-05-31. PMID:3283732. |
the objective of this study was to examine the release of insulin from cultured islet cells, taken from the pancreas of newborn and adult rats, in response to gastric inhibitory polypeptide (gip), cholecystokinin-8 (cck-8), calcitonin gene-related peptide (cgrp), and pancreastatin. |
1988-05-31 |
2023-08-11 |
rat |
| J Ishizuka, P Singh, G H Greeley, C M Townsend, C W Cooper, K Tatemoto, J C Thompso. A comparison of the insulinotropic and the insulin-inhibitory actions of gut peptides on newborn and adult rat islet cells. Pancreas. vol 3. issue 1. 1988-05-31. PMID:3283732. |
gip (10(-9)-10(-7) m) potentiated glucose-stimulated release of insulin in a dose-dependent fashion from both newborn and adult islet cells. |
1988-05-31 |
2023-08-11 |
rat |
| S K Swanston-Flatt, P R Flat. Effects of amino acids, hormones and drugs on insulin release and 45Ca uptake by transplantable rat insulinoma cells maintained in tissue culture. General pharmacology. vol 19. issue 2. 1988-05-12. PMID:2832246. |
responsiveness to acetylcholine (stimulation of insulin release and 45ca uptake) and to gip (stimulation of insulin release) was demonstrated. |
1988-05-12 |
2023-08-11 |
rat |
| J Ishizuka, G H Greeley, C W Cooper, J C Thompso. Effect of calcitonin gene-related peptide on glucose and gastric inhibitory polypeptide-stimulated insulin release from cultured newborn and adult rat islet cells. Regulatory peptides. vol 20. issue 1. 1988-05-06. PMID:3281189. |
in adult rat islet cells, cgrp (10(-10) to 10(-8) m) significantly inhibited glucose-stimulated and gastric inhibitory polypeptide (gip)-potentiated insulin secretion, but in newborn rat islet cells, cgrp did not inhibit glucose-stimulated insulin secretion. |
1988-05-06 |
2023-08-11 |
rat |