| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Solcia, L Usellini, R Buffa, G Rindi, L Villani, C Zampatti, E Silin. Endocrine cells producing regulatory peptides. Experientia. vol 43. issue 7. 1987-08-20. PMID:3297770. |
gastrin, xenopsin, cholecystokinin (cck), somatostatin, motilin, secretin, gip (gastric inhibitory polypeptide), neurotensin, glicentin/glucagon-37 and pyy (peptide tyrosine tyrosine) are the main products of gastrointestinal endocrine cells; glucagon, crf (corticotropin releasing factor), somatostatin, pp (pancreatic polypeptide) and grf (growth hormone releasing factor), in addition to insulin, are produced in pancreatic islet cells; bombesin-related peptides are the main markers of pulmonary endocrine cells; calcitonin and cgrp (calcitonin gene-related peptide) occur in thyroid and extrathyroid c cells; acth and endorphins in anterior and intermediate lobe pituitary cells, alpha-msh and clip (corticotropin-like intermediate lobe peptide) in intermediate lobe cells; met- and leu-enkephalins and related peptides in adrenal medullary and paraganglionic cells as well as in some gut (enterochromaffin) cells; npy (neuropeptide y) in adrenaline-type adrenal medullary cells, etc.. |
1987-08-20 |
2023-08-11 |
Not clear |
| R S Scott, T Donnell. No effect of gliclazide on gastric inhibitory polypeptide (GIP) in type II diabetes. Diabetes research and clinical practice. vol 3. issue 3. 1987-08-10. PMID:3595434. |
blood samples were collected between 0 and 240 min post-prandially and assayed for glucose, insulin, c-peptide, glucagon, pancreatic polypeptide, gastric inhibitory polypeptide (gip), and gastrin. |
1987-08-10 |
2023-08-11 |
human |
| B Hagander, I Björck, N G Asp, S Efendić, J Holm, P Nilsson-Ehle, I Lundquist, B Schersté. Rye products in the diabetic diet. Postprandial glucose and hormonal responses in non-insulin-dependent diabetic patients as compared to starch availability in vitro and experiments in rats. Diabetes research and clinical practice. vol 3. issue 2. 1987-06-09. PMID:2436870. |
the levels of insulin, c-peptide, gastric inhibitory polypeptide (gip), glucagon, somatostatin, triglyceride and glycerol were followed after the breakfast meals. |
1987-06-09 |
2023-08-11 |
rat |
| M K Mueller, T Scheck, V Dreesmann, A Miodonski, H Goebel. GIP potentiates CCK stimulated pancreatic enzyme secretion: correlation of anatomical structures with the effects of GIP and CCK on amylase secretion. Pancreas. vol 2. issue 1. 1987-06-08. PMID:2437570. |
gip at a concentration as low as 2 ng/ml or exogenous rat insulin potentiated cck-stimulated pancreatic enzyme secretion. |
1987-06-08 |
2023-08-11 |
rat |
| M K Mueller, T Scheck, V Dreesmann, A Miodonski, H Goebel. GIP potentiates CCK stimulated pancreatic enzyme secretion: correlation of anatomical structures with the effects of GIP and CCK on amylase secretion. Pancreas. vol 2. issue 1. 1987-06-08. PMID:2437570. |
to have similar effects as insulin which is endogenously released by gip, about 30 times more exogenous rat insulin has to be infused. |
1987-06-08 |
2023-08-11 |
rat |
| A Ohneda, T Kobayashi, J Nihe. Glucose-induced responses of insulin and gastric inhibitory polypeptide in various animal models. The Tohoku journal of experimental medicine. vol 151. issue 1. 1987-06-02. PMID:3554613. |
glucose-induced response of plasma gip was exaggerated in all the groups compared with group n. the regression equation reported by lauritsen and moody was obtained in each dog from the ratio of plasma insulin to blood glucose and from plasma gip. |
1987-06-02 |
2023-08-11 |
dog |
| A Ohneda, T Kobayashi, J Nihe. Glucose-induced responses of insulin and gastric inhibitory polypeptide in various animal models. The Tohoku journal of experimental medicine. vol 151. issue 1. 1987-06-02. PMID:3554613. |
the slope of the regression line was elevated in group gj and reduced in group v. however, groups d and a did not reveal any difference in the slope of the regression line compared with group n. from the present study, it might be concluded that the b-values in lauritsen and moody's equation indicates the sensitivity of the b cell in the pancreatic islet and that gip secretion plays an important role in the glucose-induced insulin response even in the conditions with various surgical modifications. |
1987-06-02 |
2023-08-11 |
dog |
| O Lawaetz, S R Bloom, H Stimpel, O J Siemsse. Effect of soya bean oil on symptoms, gastric emptying and gut hormone release in patients with postvagotomy symptoms. Annales chirurgiae et gynaecologiae. vol 75. issue 6. 1987-05-29. PMID:3555275. |
in a preliminary study the effect of an aperitif of a stable fat emulsion on symptoms, gastric emptying of a hypertonic glucose meal and associated release of insulin, neurotensin, enteroglucagon, gastric inhibitory polypeptide (gip) and vasoactive intestinal polypeptide (vip) was evaluated in 9 patients with postprandial gastrointestinal discomfort after vagotomy. |
1987-05-29 |
2023-08-11 |
Not clear |
| C J Bailey, P R Flatt, P Kwasowski, M Adam. Gastric inhibitory polypeptide and the entero-insular axis in streptozotocin diabetic mice. Diabete & metabolisme. vol 12. issue 6. 1987-04-07. PMID:3545933. |
in spite of marked hyperglycaemia, fat-stimulated gip release did not raise plasma insulin in streptozotocin diabetic mice. |
1987-04-07 |
2023-08-11 |
mouse |
| C J Bailey, P R Flatt, P Kwasowski, M Adam. Gastric inhibitory polypeptide and the entero-insular axis in streptozotocin diabetic mice. Diabete & metabolisme. vol 12. issue 6. 1987-04-07. PMID:3545933. |
the results indicate that streptozotocin diabetes in mice is associated with ineffectiveness of the entero-insular axis, despite elevated gip concentrations, which are probably mediated through hyperphagia and defective feedback inhibition by insulin on intestinal k cells. |
1987-04-07 |
2023-08-11 |
mouse |
| M M Loubatières-Marian. [Current data on insulin secretion and its regulation]. Journal de pharmacologie. vol 17 Suppl 2. 1987-04-01. PMID:2881028. |
of the gastrointestinal hormones, gip (gastric inhibitory polypeptide) appears to play the most important physiological role in potentiating the insulin secretory effect of glucose. |
1987-04-01 |
2023-08-11 |
Not clear |
| L Tappy, R Chiolero, J P Randin, P Burckhardt, J P Felbe. Effects of cholinergic stimulation and antagonism on plasma insulin concentration in lean and obese human subjects. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 12. 1987-03-31. PMID:3546047. |
the effect of cholinomimetic stimulation by infusion of edrophonium chloride or muscarinic blockade by infusion of atropine sulfate on insulin and gip secretion was studied in normal lean subjects during eu- and hyperglycemia. |
1987-03-31 |
2023-08-11 |
human |
| L Tappy, R Chiolero, J P Randin, P Burckhardt, J P Felbe. Effects of cholinergic stimulation and antagonism on plasma insulin concentration in lean and obese human subjects. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 12. 1987-03-31. PMID:3546047. |
cholinomimetic stimulation led to a slight non-significant increase and muscarinic blockade to a slight, non-significant suppression of both gip and insulin. |
1987-03-31 |
2023-08-11 |
human |
| L Tappy, R Chiolero, J P Randin, P Burckhardt, J P Felbe. Effects of cholinergic stimulation and antagonism on plasma insulin concentration in lean and obese human subjects. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 12. 1987-03-31. PMID:3546047. |
the effect of atropine infusion on fasting plasma insulin and gip was subsequently studied in 11 obese patients and 10 lean subjects. |
1987-03-31 |
2023-08-11 |
human |
| L Tappy, R Chiolero, J P Randin, P Burckhardt, J P Felbe. Effects of cholinergic stimulation and antagonism on plasma insulin concentration in lean and obese human subjects. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 12. 1987-03-31. PMID:3546047. |
muscarinic antagonism by atropine led to a transient non-significant suppression of gip and insulin in lean subjects, but to a significant, sustained suppression of these hormones in obese patients. |
1987-03-31 |
2023-08-11 |
human |
| L Tappy, R Chiolero, J P Randin, P Burckhardt, J P Felbe. Effects of cholinergic stimulation and antagonism on plasma insulin concentration in lean and obese human subjects. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 12. 1987-03-31. PMID:3546047. |
insulin and gip levels were however, not suppressed to control values after atropine administration in obese patients. |
1987-03-31 |
2023-08-11 |
human |
| W E Schmidt, E G Siegel, H Kümmel, B Gallwitz, W Creutzfeld. Commercially available preparations of porcine glucose-dependent insulinotropic polypeptide (GIP) contain a biologically inactive GIP-fragment and cholecystokinin-33/-39. Endocrinology. vol 120. issue 2. 1987-03-04. PMID:3542510. |
hplc-pure gip(1-42) stimulated insulin release in rat isolated pre-cultured pancreatic islets in the presence of 16.7 mm glucose up to 240% vs. control, whereas the fragment des-tyr-ala-gip(3-42) did neither increase insulin release nor exhibit antagonistic activity to gip(1-42) at 100 ng/ml. |
1987-03-04 |
2023-08-11 |
rat |
| P Thor, J Laskiewicz, J W Konturek, S J Konturek, W Creutzfeld. Role of GIP and insulin in glucose-induced changes in intestinal motility patterns. The American journal of physiology. vol 252. issue 1 Pt 1. 1987-03-02. PMID:3101511. |
role of gip and insulin in glucose-induced changes in intestinal motility patterns. |
1987-03-02 |
2023-08-11 |
Not clear |
| P Thor, J Laskiewicz, J W Konturek, S J Konturek, W Creutzfeld. Role of GIP and insulin in glucose-induced changes in intestinal motility patterns. The American journal of physiology. vol 252. issue 1 Pt 1. 1987-03-02. PMID:3101511. |
this study was designed to correlate the intestinal motility patterns with duodenal glucose loads and the increments in plasma gastric inhibitory peptide (gip) and insulin levels after these loads or after the administration of exogenous hormones in conscious dogs. |
1987-03-02 |
2023-08-11 |
Not clear |
| P Thor, J Laskiewicz, J W Konturek, S J Konturek, W Creutzfeld. Role of GIP and insulin in glucose-induced changes in intestinal motility patterns. The American journal of physiology. vol 252. issue 1 Pt 1. 1987-03-02. PMID:3101511. |
isotonic glucose instilled intraduodenally at lower loads (5.2-42.4 mmol/h) only caused a moderate increase in spike activity, but at higher loads (84.8 mmol/h) it disrupted migrating myoelectric complexes (mmc), being accompanied by marked increases in plasma gip and insulin levels. |
1987-03-02 |
2023-08-11 |
Not clear |