| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raquel Sitcheran, Pankaj Gupta, Paul B Fisher, Albert S Baldwi. Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. The EMBO journal. vol 24. issue 3. 2005-03-28. PMID:15660126. |
the glutamate transporter gene, eaat2/glt-1, is induced by epidermal growth factor (egf) and downregulated by tumor necrosis factor alpha (tnfalpha). |
2005-03-28 |
2023-08-12 |
Not clear |
| Joanna Rozyczka, Maciej Figiel, Jürgen Engel. Endothelins negatively regulate glial glutamate transporter expression. Brain pathology (Zurich, Switzerland). vol 14. issue 4. 2005-02-14. PMID:15605988. |
although several injury-induced growth factors such as epidermal growth factor (egf) and transforming growth factor alpha (tgfalpha) potently stimulate the expression of glutamate transporters in cultured astroglia, glt-1 and/or glast expression temporarily decreases during acute brain injuries eventually contributing to secondary neuronal cell death. |
2005-02-14 |
2023-08-12 |
Not clear |
| Syma Iqbal, Heinz-Josef Len. Integration of novel agents in the treatment of colorectal cancer. Cancer chemotherapy and pharmacology. vol 54 Suppl 1. 2004-12-22. PMID:15309512. |
the most promising of these agents are cetuximab, which blocks the binding of egf and transforming growth factor alpha (tgf-alpha) to egfr, and bevacizumab, which binds free vegf. |
2004-12-22 |
2023-08-12 |
human |
| Rachel W S Chan, Kjiana E Schwab, Caroline E Garget. Clonogenicity of human endometrial epithelial and stromal cells. Biology of reproduction. vol 70. issue 6. 2004-12-10. PMID:14766732. |
in serum-free medium, transforming growth factor-alpha (tgf alpha), epidermal growth factor (egf), platelet-derived growth factor-bb (pdgf-bb) strongly supported clonogenicity of epithelial cells, while leukemia-inhibitory factor (lif), hepatocyte growth factor (hgf), stem-cell factor (scf), insulin-like growth factor-i (igf- i) were weakly supportive, and basic fibroblast growth factor (bfgf) was without effect. |
2004-12-10 |
2023-08-12 |
human |
| Paweł Krawczyk, Sylwia Chocholska, Janusz Milanowsk. Anti-HER therapeutic agents in the treatment of non-small-cell lung cancer. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina. vol 58. issue 1. 2004-11-09. PMID:15314969. |
dimerised on binding with a number of ligands, including epidermal growth factor (egf) and transforming growth factor alpha (tgfalpha), these proteins stimulate epithelial cell proliferation. |
2004-11-09 |
2023-08-12 |
Not clear |
| Nicola J Jordan, Julia M W Gee, Denise Barrow, Alan E Wakeling, Robert I Nicholso. Increased constitutive activity of PKB/Akt in tamoxifen resistant breast cancer MCF-7 cells. Breast cancer research and treatment. vol 87. issue 2. 2004-11-02. PMID:15377841. |
the ligands for the egfr/erbb1 receptor, egf (epidermal growth factor) and tgf alpha (transforming growth factor- alpha ) demonstrate an increased ability to activate akt in tam-r compared with parental mcf-7 cells and it is proposed that the preferred autocrine or paracrine activation of akt occurs via the erbb heterodimer egfr/erbb2 in tam-r cells. |
2004-11-02 |
2023-08-12 |
Not clear |
| B Witek-Zawada, A Ko. Regulation of expression of stromyelysin-1 by proinflammatory cytokines in mouse brain astrocytes. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 54. issue 4. 2004-09-16. PMID:14726605. |
interleukin-1-beta (il-1beta), tumor necrosis factor alpha (tnfalpha) and a mixture of il-1, tnf and epidermal growth factor (egf) significantly increased the level of stromelysin-1 mrna in mouse astrocytes while interferon-gamma (ifn-gamma) inhibited this response or was without effect. |
2004-09-16 |
2023-08-12 |
mouse |
| Vassilios J Bezzerides, I Scott Ramsey, Suhas Kotecha, Anna Greka, David E Clapha. Rapid vesicular translocation and insertion of TRP channels. Nature cell biology. vol 6. issue 8. 2004-08-27. PMID:15258588. |
epidermal growth factor (egf)-induced incorporation of functional trp channels requires phosphatidylinositide 3-kinase (pi(3)k), the rho gtpase rac1 and phosphatidylinositol 4-phosphate 5-kinase (pip(5)k alpha). |
2004-08-27 |
2023-08-12 |
Not clear |
| Barbara D Abbott, Tien-Min Lin, Nathan T Rasmussen, Ralph M Albrecht, Judith E Schmid, Richard E Peterso. Lack of expression of EGF and TGF-alpha in the fetal mouse alters formation of prostatic epithelial buds and influences the response to TCDD. Toxicological sciences : an official journal of the Society of Toxicology. vol 76. issue 2. 2004-08-06. PMID:14514962. |
epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha), both of which bind the egf receptor (egfr), are expressed in human and rodent developing prostate. |
2004-08-06 |
2023-08-12 |
mouse |
| James B Morris, Tam M Pham, Bronywn Kenney, Karen E Sheppard, Elizabeth A Woodcoc. UTP transactivates epidermal growth factor receptors and promotes cardiomyocyte hypertrophy despite inhibiting transcription of the hypertrophic marker gene, atrial natriuretic peptide. The Journal of biological chemistry. vol 279. issue 10. 2004-07-06. PMID:14676212. |
as reported previously for other g(q)-coupled receptors, stimulation of alpha(1)-adrenergic receptors with phenylephrine (50 microm) caused phosphorylation of epidermal growth factor (egf) receptors as well as activation of erk1/2, cellular growth, and anp transcription. |
2004-07-06 |
2023-08-12 |
rat |
| Isaac Rabinovitz, Lobsang Tsomo, Arthur M Mercuri. Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes. Molecular and cellular biology. vol 24. issue 10. 2004-06-17. PMID:15121854. |
using cos-7 cells, which assemble hemidesmosomes type ii upon exogenous expression of the alpha 6 beta 4 integrin, we observed that expression of a beta 4 construct containing ser-->ala mutations of s(1356), s(1360), and s(1364) reduced the ability of egf to disrupt hemidesmosomes and that this effect appears to involve cooperation among these phosphorylation sites. |
2004-06-17 |
2023-08-12 |
Not clear |
| B R Huang, L W Cai, X Z Xian. [The basic and applied study on the epidermal growth factor]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 23. issue 2. 2004-06-10. PMID:12905898. |
relevant studies show that recombinant egf consisting of 51 amino acids can be secreted into the medium under the control of the alpha factor leading sequence in the yeast cells. |
2004-06-10 |
2023-08-12 |
rat |
| Alan J Russell, Edgar F Fincher, Linda Millman, Robyn Smith, Veronica Vela, Elizabeth A Waterman, Clara N Dey, Shireen Guide, Valerie M Weaver, M Peter Marinkovic. Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin. Journal of cell science. vol 116. issue Pt 17. 2004-05-28. PMID:12865436. |
in the absence of alpha 6 beta 4 integrin ligation, rac1 activation became tempered and egf chemotaxis proceeded through an alternate mechanism that depended upon alpha 3 beta 1 integrin and was characterized by cell scattering. |
2004-05-28 |
2023-08-12 |
Not clear |
| Sen-hua Li, Ze-ming Zeng, Guan-chao Lai, Lai-yu L. [The level of serum tumor necrosis factor-alpha and epidermal growth factor in patients with medicament-like dermatitis by trichloroethylene and its clinical significance]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 21. issue 6. 2004-05-27. PMID:14761356. |
to investigate the level of tumor necrosis factor alpha (tnf-alpha) and epidermal growth factor (egf) in patients with medicament-like dermatitis by trichloroethylene (dmlt). |
2004-05-27 |
2023-08-12 |
Not clear |
| Heinrich Sauer, Katrin Wefer, Vito Vetrugno, Maurizio Pocchiari, Cornelia Gissel, Agapios Sachinidis, Jürgen Hescheler, Maria Wartenber. Regulation of intrinsic prion protein by growth factors and TNF-alpha: the role of intracellular reactive oxygen species. Free radical biology & medicine. vol 35. issue 6. 2004-05-12. PMID:12957651. |
prpc protein was significantly increased when glioma spheroids were treated with either atp, nerve growth factor (ngf), epidermal growth factor (egf), or tumor necrosis factor alpha (tnf-alpha), whereas mrna levels as evaluated by reverse transcriptase-polymerase chain reaction (rt-pcr) remained unchanged. |
2004-05-12 |
2023-08-12 |
Not clear |
| Hung Huynh, Thi Thanh Tuyen Nguyen, Eli Chan, Evelyne Tra. Inhibition of ErbB-2 and ErbB-3 expression by quercetin prevents transforming growth factor alpha (TGF-alpha)- and epidermal growth factor (EGF)-induced human PC-3 prostate cancer cell proliferation. International journal of oncology. vol 23. issue 3. 2004-05-04. PMID:12888923. |
inhibition of erbb-2 and erbb-3 expression by quercetin prevents transforming growth factor alpha (tgf-alpha)- and epidermal growth factor (egf)-induced human pc-3 prostate cancer cell proliferation. |
2004-05-04 |
2023-08-12 |
human |
| Anja Nohe, Eleonora Keating, Crystal Loh, Michael T Underhill, Nils O Peterse. Caveolin-1 isoform reorganization studied by image correlation spectroscopy. Faraday discussions. vol 126. 2004-05-04. PMID:14992406. |
bmp as well as egf stimulation leads to a rearrangement of the caveolin-1 p isoform into domains enriched in the caveolin-1 alpha isoform. |
2004-05-04 |
2023-08-12 |
Not clear |
| Anne L Symon. Reduced growth hormone receptor immunoreactivity in osteoclasts adjacent to the erupting molar in the incisor-absent (osteopetrotic) rat. European journal of oral sciences. vol 111. issue 6. 2004-04-09. PMID:14632687. |
growth factors that regulate local bone metabolism include growth hormone (gh), insulin-like growth factor-i (igf-i), epidermal growth factor (egf) and interleukin-1 alpha (il-1alpha). |
2004-04-09 |
2023-08-12 |
rat |
| Nicole Maas-Szabowski, Anja Stärker, Norbert E Fuseni. Epidermal tissue regeneration and stromal interaction in HaCaT cells is initiated by TGF-alpha. Journal of cell science. vol 116. issue Pt 14. 2004-04-07. PMID:12771184. |
addition of tgf- alpha or egf stimulated hacat cell proliferation but, even more effectively, suppressed apoptosis, thus facilitating the formation of a regularly stratified epithelium. |
2004-04-07 |
2023-08-12 |
mouse |
| J-L Yang, X-J Qu, P J Russell, D Goldstei. Regulation of epidermal growth factor receptor in human colon cancer cell lines by interferon alpha. Gut. vol 53. issue 1. 2004-02-26. PMID:14684586. |
in this study, we examined: (a) regulation of epidermal growth factor receptor (egfr) expression in a panel of 10 human colon cancer cell lines using interferon alpha (ifn-alpha); (b) ability of ifn-alpha to inhibit cell proliferation; and (c) sensitivity of ifn-alpha pretreated cells to egf. |
2004-02-26 |
2023-08-12 |
human |