| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jill M Ricono, Miller Huang, Leo A Barnes, Steven K Lau, Sara M Weis, David D Schlaepfer, Steven K Hanks, David A Cheres. Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis. Cancer research. vol 69. issue 4. 2009-03-24. PMID:19208836. |
previously, we showed that epidermal growth factor (egf) stimulation of pancreatic carcinoma cells led to invasion and metastasis that was blocked by antagonists of integrin alpha(v)beta(5). |
2009-03-24 |
2023-08-12 |
Not clear |
| Jill M Ricono, Miller Huang, Leo A Barnes, Steven K Lau, Sara M Weis, David D Schlaepfer, Steven K Hanks, David A Cheres. Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis. Cancer research. vol 69. issue 4. 2009-03-24. PMID:19208836. |
specifically, egf receptor (egfr)-induced src activity leads to phosphorylation of a region within the cas substrate domain, which is essential for rap1 and alpha(v)beta(5) activation. |
2009-03-24 |
2023-08-12 |
Not clear |
| Yuichi Abe, Hiroyuki Nawa, Hisaaki Namb. Activation of epidermal growth factor receptor ErbB1 attenuates inhibitory synaptic development in mouse dentate gyrus. Neuroscience research. vol 63. issue 2. 2009-03-17. PMID:19071166. |
ligands for the epidermal growth factor receptor erbb1, such as epidermal growth factor (egf) and transforming growth factor alpha (tgfalpha), negatively regulate synaptic maturation of gabaergic neurons in the developing neocortex. |
2009-03-17 |
2023-08-12 |
mouse |
| Nikola Holtkamp, Elke Malzer, Jan Zietsch, Ali Fuat Okuducu, Jana Mucha, Christian Mawrin, Victor-F Mautner, Hans-Ulrich Schildhaus, Andreas von Deimlin. EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy. Neuro-oncology. vol 10. issue 6. 2009-02-20. PMID:18650488. |
the egfr ligands transforming growth factor alpha and egf were more strongly expressed in mpnsts than in neurofibromas. |
2009-02-20 |
2023-08-12 |
Not clear |
| Kerem Bulut, Peter Felderbauer, Karoline Hoeck, Wolfgang E Schmidt, Peter Hoffman. Increased duodenal expression of transforming growth factor-alpha and epidermal growth factor during experimental colitis in rats. European journal of gastroenterology & hepatology. vol 20. issue 10. 2008-12-15. PMID:18787466. |
epidermal growth factor (egf) and transforming growth factor alpha (tgfalpha) protect gastrointestinal mucosa against injury. |
2008-12-15 |
2023-08-12 |
rat |
| J Oliva-Hernández, J F Pérez-Gutiérre. Localization of the epidermal growth factor (EGF) in the epididymis and accessory genital glands of the boar and functional effects on spermatozoa. Theriogenology. vol 70. issue 7. 2008-12-04. PMID:18672282. |
the aim of this work was to investigate the localization of egf, transforming growth factor alpha (tgfalpha) and epidermal growth factor receptor (egfr) in boar epididymis and accessory genital glands, as well as study the presence of egfr and the effects of egf on boar spermatozoa. |
2008-12-04 |
2023-08-12 |
Not clear |
| Zhi-Bo Han, He Ren, Hui Zhao, Ying Chi, Ke Chen, Bin Zhou, Yong-jun Liu, Lei Zhang, Bin Xu, Bin Liu, Renchi Yang, Zhong-Chao Ha. Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis. vol 29. issue 10. 2008-10-14. PMID:18339685. |
hypoxia-inducible factor (hif)-1 alpha directly enhances the transcriptional activity of stem cell factor (scf) in response to hypoxia and epidermal growth factor (egf). |
2008-10-14 |
2023-08-12 |
human |
| Noriko Tsuda, Makoto Mizuno, Takayuki Yamanaka, Toshi Komurasaki, Makoto Yoshimoto, Hiroyuki Naw. Common behavioral influences of the ErbB1 ligands transforming growth factor alpha and epiregulin administered to mouse neonates. Brain & development. vol 30. issue 8. 2008-09-30. PMID:18313247. |
ligands for epidermal growth factor (egf) receptor (erbb1), such as egf, transforming growth factor alpha (tgfalpha), and epiregulin, are enriched in body fluids and blood and regulate development of various peripheral organs. |
2008-09-30 |
2023-08-12 |
mouse |
| Caroline E Gargett, Rachel W S Chan, Kjiana E Schwa. Hormone and growth factor signaling in endometrial renewal: role of stem/progenitor cells. Molecular and cellular endocrinology. vol 288. issue 1-2. 2008-09-16. PMID:18403104. |
several growth factors are required for cfu activity: epidermal growth factor (egf), transforming growth factor alpha (tgfalpha) and platelet-derived growth factor bb (pdgf-bb) for both epithelial and stromal cfu, and basic fibroblast growth factor (bfgf) for stromal, but not epithelial cfu. |
2008-09-16 |
2023-08-12 |
mouse |
| B Li, T Du, H Li, L Gu, H Zhang, J Huang, L Hertz, L Pen. Signalling pathways for transactivation by dexmedetomidine of epidermal growth factor receptors in astrocytes and its paracrine effect on neurons. British journal of pharmacology. vol 154. issue 1. 2008-07-17. PMID:18311185. |
stimulation of astrocytes by the alpha(2)-adrenoceptor agonist dexmedetomidine, a neuroprotective drug, transactivates epidermal growth factor (egf) receptors. |
2008-07-17 |
2023-08-12 |
Not clear |
| Dominko Carev, Marijan Saraga, Mirna Saraga-Babi. Expression of intermediate filaments, EGF and TGF-alpha in early human kidney development. Journal of molecular histology. vol 39. issue 2. 2008-07-03. PMID:18080773. |
the spatial and temporal expression patterns of cytokeratins, vimentin, epithelial growth factor (egf) and transforming growth factor alpha (tgf-alpha), were investigated in the 5-9-week old human mesonephros and metanephros. |
2008-07-03 |
2023-08-12 |
human |
| Kristjana Einarsdóttir, Hatef Darabi, Yi Li, Yen Ling Low, Yu Qing Li, Carine Bonnard, Arvid Sjölander, Kamila Czene, Sara Wedrén, Edison T Liu, Per Hall, Keith Humphreys, Jianjun Li. ESR1 and EGF genetic variation in relation to breast cancer risk and survival. Breast cancer research : BCR. vol 10. issue 1. 2008-06-11. PMID:18271972. |
oestrogen receptor alpha (esr1) is the main mediator of oestrogen effect in breast epithelia and has also been shown to be activated by epidermal growth factor (egf). |
2008-06-11 |
2023-08-12 |
Not clear |
| P Zhou, D J Liu, M Cang, Y Z Ma, D S Yang, H J Li, L M Wang, S Bou, H L Fen. TGFalpha and EGFR in ovine preimplantation embryos and effects on development. Animal reproduction science. vol 104. issue 2-4. 2008-05-29. PMID:17412533. |
the present study aimed to assess location and relative amounts of transforming growth factor alpha (tgfalpha) and its receptor (egfr) in ovine oocytes and preimplantation embryos by using immunohistochemical technique that was graded on a relative scale of 0-3, with 0 representing absence of staining, and 3 exhibiting prominent staining, and to evaluate the effects of tgfalpha/egf on in vitro development of preimplantation embryos by adding different concentrations of egf and tgfalpha to culture medium. |
2008-05-29 |
2023-08-12 |
Not clear |
| Mary C Farach-Carson, Anissa J Brown, Megan Lynam, Jeffrey B Safran, Daniel D Carso. A novel peptide sequence in perlecan domain IV supports cell adhesion, spreading and FAK activation. Matrix biology : journal of the International Society for Matrix Biology. vol 27. issue 2. 2008-05-19. PMID:17997086. |
with the exception of its unique domain i, each of perlecan's other four domains shares sequence similarity to other protein families including low density lipoprotein (ldl) receptor, laminin alpha chain, neural cell adhesion molecule (ncam), immunoglobulin (ig) superfamily members, and epidermal growth factor (egf). |
2008-05-19 |
2023-08-12 |
human |
| Tzindilú Molina-Muñoz, M Teresa Romero-Avila, S Eréndira Avendaño-Vázquez, J Adolfo García-Sáin. Phosphorylation, desensitization and internalization of human alpha1B-adrenoceptors induced by insulin-like growth factor-I. European journal of pharmacology. vol 578. issue 1. 2008-05-06. PMID:17915215. |
igf-i induced alpha(1b)-adrenoceptor phosphorylation, which was markedly reduced by the following agents: pertussis toxin, a metalloproteinase inhibitor, diphtheria toxin mutant crm 197, an epidermal growth factor (egf) receptor intrinsic kinase activity inhibitor, and by phosphoinositide 3-kinase and protein kinase c inhibitors. |
2008-05-06 |
2023-08-12 |
human |
| Jian Gu, Lili Chen, Marie A Shatos, J David Rios, Abha Gulati, Robin R Hodges, Darlene A Dart. Presence of EGF growth factor ligands and their effects on cultured rat conjunctival goblet cell proliferation. Experimental eye research. vol 86. issue 2. 2008-04-16. PMID:18155194. |
in the rat conjunctiva, the presence of the egf family members epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), heparin binding egf (hb-egf), and heregulin was determined by rt-pcr. |
2008-04-16 |
2023-08-12 |
rat |
| Ronit Mor-Cohen, Nurit Rosenberg, Hava Peretz, Meytal Landau, Barry S Coller, Abdalla Awidi, Uri Seligsoh. Disulfide bond disruption by a beta 3-Cys549Arg mutation in six Jordanian families with Glanzmann thrombasthenia causes diminished production of constitutively active alpha IIb beta 3. Thrombosis and haemostasis. vol 98. issue 6. 2008-02-26. PMID:18064323. |
cysteine residues in the beta 3 epidermal growth factor (egf) domains are involved in alpha iib beta 3 formation and activation. |
2008-02-26 |
2023-08-12 |
Not clear |
| Mikio Momoeda, Sayaka Fukuta, Yuriko Iwamori, Yuji Taketani, Masao Iwamor. Prolactin-dependent expression of GD1 alpha ganglioside, as a component of milk fat globule, in the murine mammary glands. Journal of biochemistry. vol 142. issue 4. 2008-01-22. PMID:17875552. |
when the mammary epithelial cells at 15th day of gestation were cultured in prolactin- and epidermal growth factor (egf)-containing media, the synthesis of fat globules and casein, together with the enhanced synthesis of gd1 alpha, were observed in the cells in prolactin medium, indicating that synthesis of gd1 alpha occurs in association with milk production as a prolactin-dependent event. |
2008-01-22 |
2023-08-12 |
mouse |
| Bénédicte Buffin-Meyer, Pierre-Antoine Crassous, Christine Delage, Colette Denis, Stéphane Schaak, Hervé Pari. EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing. European journal of pharmacology. vol 574. issue 2-3. 2008-01-17. PMID:17655843. |
egf receptor transactivation and pi3-kinase mediate stimulation of erk by alpha(2a)-adrenoreceptor in intestinal epithelial cells: a role in wound healing. |
2008-01-17 |
2023-08-12 |
human |
| Bénédicte Buffin-Meyer, Pierre-Antoine Crassous, Christine Delage, Colette Denis, Stéphane Schaak, Hervé Pari. EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing. European journal of pharmacology. vol 574. issue 2-3. 2008-01-17. PMID:17655843. |
in conclusion, alpha(2a)-adrenoreceptor activates erk and akt in intestinal cells by a common pathway which depends on pi3-kinase activation and results from egf receptor transactivation, via an autocrine/paracrine pathway implying mmp activation and heparin-binding-egf shedding. |
2008-01-17 |
2023-08-12 |
human |