| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hanumantha R Ancha, Hari B Ancha, Dustin S Tedesco, Angela R Ward, Richard F Hart. Inhibition of epidermal growth factor receptor activation enhances in vivo histamine-stimulated gastric acid secretion in the rat. Digestive diseases and sciences. vol 51. issue 2. 2006-04-11. PMID:16534669. |
epidermal growth factor (egf) and transforming growth factor alpha (tgfalpha) have been shown to inhibit gastric acid secretion through stimulation of the egf receptor (egfr). |
2006-04-11 |
2023-08-12 |
rat |
| Aaron R Klooster, Suzanne M Bernie. Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte. Arthritis research & therapy. vol 7. issue 1. 2006-03-24. PMID:15642133. |
in the present study, we investigated the effects of tumor necrosis factor alpha (tnf-alpha) and epidermal growth factor (egf) on chondrocyte morphology and matrix gene expression. |
2006-03-24 |
2023-08-12 |
rat |
| Sujin Park, Fumio Matsumur. Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A. Toxicology. vol 217. issue 2-3. 2006-03-02. PMID:16213648. |
in addition, we found that, in this cell line, such anti-apoptotic action of tcdd resembles that of exogenously added egf or tgf alpha. |
2006-03-02 |
2023-08-12 |
human |
| Lene E Johannessen, Nina Marie Pedersen, Ketil Winther Pedersen, Inger Helene Madshus, Espen Stan. Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits. Molecular and cellular biology. vol 26. issue 2. 2006-02-13. PMID:16382132. |
however, epidermal growth factor (egf)-induced endocytosis of the egf receptor (egfr) was inhibited only in cells where the alpha subunit had been knocked down. |
2006-02-13 |
2023-08-12 |
Not clear |
| Elzbieta Pluskota, Olga I Stenina, Irene Krukovets, Dorota Szpak, Eric J Topol, Edward F Plo. Mechanism and effect of thrombospondin-4 polymorphisms on neutrophil function. Blood. vol 106. issue 12. 2006-01-18. PMID:16099885. |
integrin alpha(m)beta2 was identified as the tsp-4 receptor mediating these responses, and the 3 epidermal growth factor (egf)-like domains of tsp-4 harboring the snps interacted with the alpha(m)i-domain. |
2006-01-18 |
2023-08-12 |
human |
| Antimo Migliaccio, Marina Di Domenico, Gabriella Castoria, Merlin Nanayakkara, Maria Lombardi, Antonietta de Falco, Antonio Bilancio, Lilian Varricchio, Alessandra Ciociola, Ferdinando Auricchi. Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action. Cancer research. vol 65. issue 22. 2006-01-18. PMID:16288052. |
interestingly, egf triggers rapid association of src with androgen receptor (ar) and estradiol receptor alpha (eralpha) in mcf-7 cells or erbeta in lncap cells. |
2006-01-18 |
2023-08-12 |
Not clear |
| Mitsuhiro Morita, Nagisa Kozuka, Rurika Itofusa, Masashi Yukawa, Yosihisa Kud. Autocrine activation of EGF receptor promotes oscillation of glutamate-induced calcium increase in astrocytes cultured in rat cerebral cortex. Journal of neurochemistry. vol 95. issue 3. 2005-12-13. PMID:16135076. |
astrocytes in our culture system expressed egf, transforming growth factor alpha (tgfalpha), bfgf and acidic fibroblast growth factor (afgf). |
2005-12-13 |
2023-08-12 |
rat |
| Jennifer Sutherland, Morgan Denyer, Stephen Britlan. Motogenic substrata and chemokinetic growth factors for human skin cells. Journal of anatomy. vol 207. issue 1. 2005-11-14. PMID:16011545. |
platelet-derived growth factor (pdgf), epidermal growth factor (egf) and alpha fibroblastic growth factor (alphafgf) all promoted cell proliferation and were chemokinetic to dermal fibroblasts, but not keratinocyte growth factor (kgf) or transforming growth factor beta (tgfbeta). |
2005-11-14 |
2023-08-12 |
human |
| Ying-Shan Piao, Yuriko Iwakura, Nobuyuki Takei, Hiroyuki Naw. Differential distributions of peptides in the epidermal growth factor family and phosphorylation of ErbB 1 receptor in adult rat brain. Neuroscience letters. vol 390. issue 1. 2005-11-07. PMID:16129559. |
using two-site enzyme immunoassays, we measured protein levels of epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), and heparin-binding epidermal growth factor (hb-egf) in adult rat brain, and compared them with the phosphorylation levels of their receptor (erbb 1). |
2005-11-07 |
2023-08-12 |
rat |
| Ying-Shan Piao, Yuriko Iwakura, Nobuyuki Takei, Hiroyuki Naw. Differential distributions of peptides in the epidermal growth factor family and phosphorylation of ErbB 1 receptor in adult rat brain. Neuroscience letters. vol 390. issue 1. 2005-11-07. PMID:16129559. |
among these erbb 1 ligands, hb-egf protein levels were higher than those of tgf alpha and those of egf were the lowest. |
2005-11-07 |
2023-08-12 |
rat |
| Takeshi Hara, Yuriko Saito, Takaaki Hirai, Kenji Nakamura, Kazuki Nakao, Motoya Katsuki, Kazuhiro Chid. Deficiency of protein kinase Calpha in mice results in impairment of epidermal hyperplasia and enhancement of tumor formation in two-stage skin carcinogenesis. Cancer research. vol 65. issue 16. 2005-10-27. PMID:16103087. |
the induction levels of epidermal growth factor (egf) receptor ligands, tumor growth factor alpha (tgf-alpha), and heparin-binding egf-like growth factor, in the skin of mutant mice by tpa treatment were significantly lower than those in the skin of wild-type mice. |
2005-10-27 |
2023-08-12 |
mouse |
| Toshifumi Takahashi, Masahide Ohmichi, Jun Kawagoe, Chika Ohshima, Masakazu Doshida, Tsuyoshi Ohta, Maki Saitoh, Akiko Mori-Abe, Botao Du, Hideki Igarashi, Kazuhiro Takahashi, Hirohisa Kurach. Growth factors change nuclear distribution of estrogen receptor-alpha via mitogen-activated protein kinase or phosphatidylinositol 3-kinase cascade in a human breast cancer cell line. Endocrinology. vol 146. issue 9. 2005-09-29. PMID:15947004. |
in the present study, to examine the dynamic changes in the localization of nuclear estrogen receptor (er)alpha induced by growth factors, we used time-lapse confocal microscopy to directly visualized eralpha fused with green fluorescent protein (gfp-eralpha) in single living cells treated with epidermal growth factor (egf) or igf-i. |
2005-09-29 |
2023-08-12 |
human |
| R J Santen, R X Song, Z Zhang, R Kumar, M-H Jeng, S Masamura, J Lawrence, L P MacMahon, W Yue, L Berstei. Adaptive hypersensitivity to estrogen: mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment. The Journal of steroid biochemistry and molecular biology. vol 95. issue 1-5. 2005-09-29. PMID:16024245. |
additional effects include activation of pi-3 kinase and mtor pathways through estradiol induced binding of er alpha to the igf-1 and egf receptors. |
2005-09-29 |
2023-08-12 |
Not clear |
| Marta Sitjà-Arnau, Miguel A Molina, Carmen Blanco-Aparicio, Laura Ferrer-Soler, Julia Lorenzo, Francesc X Avilés, Enrique Querol, Rafael de Lloren. Mechanism of action of potato carboxypeptidase inhibitor (PCI) as an EGF blocker. Cancer letters. vol 226. issue 2. 2005-09-22. PMID:16039955. |
in this paper it is shown that pci interferes with egfr activation through inhibition of receptor dimerization and receptor transphosphorylation induced by epidermal growth factor (egf) and by transforming growth factor alpha (tgf-alpha). |
2005-09-22 |
2023-08-12 |
Not clear |
| Wojciech Głabowski, Rafał Kurzawa, Barbara Wiszniewska, Tomasz Baczkowski, Mariola Marchlewicz, Paweł Breli. Growth factors effects on preimplantation development of mouse embryos exposed to tumor necrosis factor alpha. Reproductive biology. vol 5. issue 1. 2005-09-15. PMID:15821780. |
the purpose of the study was to evaluate the protective potential of epidermal growth factor (egf), insulin-like growth factors 1 and 2 (igf-i, igf-ii) and stem cell factor (scf) on in vitro development of pre-implantation mouse embryos exposed to tumor necrosis factor alpha (tnfalpha). |
2005-09-15 |
2023-08-12 |
mouse |
| Yuriko Iwakura, Ying-Shan Piao, Makoto Mizuno, Nobuyuki Takei, Akiyoshi Kakita, Hitoshi Takahashi, Hiroyuki Naw. Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857400. |
epidermal growth factor (egf) is a member of a structurally related family containing heparin-binding egf-like growth factor (hb-egf) and transforming growth factor alpha (tgfalpha) that exerts neurotrophic activity on midbrain dopaminergic neurons. |
2005-07-05 |
2023-08-12 |
human |
| Fernando M Reis, Cintia Lhullier, Maria Isabel Edelweiss, Poli Mara Spritze. In vivo assessment of the regulation of transforming growth factor alpha, epidermal growth factor (EGF), and EGF receptor in the human endometrium by medroxyprogesterone acetate. Journal of assisted reproduction and genetics. vol 22. issue 1. 2005-06-21. PMID:15807218. |
the present study evaluated the in vivo effect of medroxyprogesterone acetate (mpa) on the localization of immunoreactive transforming growth factor alpha (tgfalpha), epidermal growth factor (egf), and their common receptor (egf-r) in the human endometrium. |
2005-06-21 |
2023-08-12 |
human |
| Kenji Yokoi, Premal H Thaker, Sertac Yazici, Robert R Rebhun, Do-Hyun Nam, Junqin He, Sun-Jin Kim, James L Abbruzzese, Stanley R Hamilton, Isaiah J Fidle. Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. Cancer research. vol 65. issue 9. 2005-06-15. PMID:15867367. |
immunohistochemical analysis of 13 surgical specimens of human colon adenocarcinoma revealed that both tumor cells and tumor-associated endothelial cells in 11 of the 13 specimens expressed the epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), egf receptor (egfr), phosphorylated egfr (pegfr), vascular endothelial growth factor (vegf), vegf receptor (vegfr), and phosphorylated vegfr (pvegfr). |
2005-06-15 |
2023-08-12 |
mouse |
| Atsushi Yamada, Shioko Kimur. Induction of uteroglobin-related protein 2 (Ugrp2) expression by EGF and TGFalpha. FEBS letters. vol 579. issue 10. 2005-05-16. PMID:15811345. |
induction of ugrp2 mrna expression by epidermal growth factor (egf) and transforming growth factor alpha was examined using mouse transformed lung clara cell-derived mtcc cells. |
2005-05-16 |
2023-08-12 |
mouse |
| L L Chen, J K Johansson, R R Hodges, D Zoukhri, E Ghinelli, J D Rios, D A Dart. Differential effects of the EGF family of growth factors on protein secretion, MAPK activation, and intracellular calcium concentration in rat lacrimal gland. Experimental eye research. vol 80. issue 3. 2005-04-12. PMID:15721620. |
rt-pcr was used to detect mrna expression in the lacrimal gland of selected members of the egf family of growth factors, namely egf, transforming growth factor alpha (tgf-alpha), heparin-binding egf (hb-egf), and heregulin. |
2005-04-12 |
2023-08-12 |
rat |