| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ahmet Satici, Mustafa Guzey, Zeki Dogan, Adil Kili. Relationship between Tear TNF-alpha, TGF-beta1, and EGF levels and severity of conjunctival cicatrization in patients with inactive trachoma. Ophthalmic research. vol 35. issue 6. 2004-02-26. PMID:14688418. |
tear tumor necrosis factor alpha (tnf-alpha), transforming growth factor beta 1 (tgf-beta1), and epidermal growth factor (egf) levels were determined in patients with inactive trachoma, and a possible relation between these cytokines and conjunctival cicatrization severity was investigated. |
2004-02-26 |
2023-08-12 |
human |
| Shinichi Miyagawa, Yoshinao Katsu, Hajime Watanabe, Taisen Iguch. Estrogen-independent activation of erbBs signaling and estrogen receptor alpha in the mouse vagina exposed neonatally to diethylstilbestrol. Oncogene. vol 23. issue 2. 2004-02-03. PMID:14647453. |
we characterized the expression of epidermal growth factor (egf)-like growth factors (egf, transforming growth factor alpha (tgf-alpha), heparin-binding egf-like growth factor (hb-egf), betacellulin (btc), amphiregulin (apr), epiregulin (epr) and neuregulin (nrg) 1) and erbb receptors (egf receptor (egfr), erbb2/neu, erbb3 and erbb4) in the vaginae of mice treated either neonatally (0-4 day) or as adults (55-59 day) with estrogens. |
2004-02-03 |
2023-08-12 |
mouse |
| Seiji Mori, Motonari Tanaka, Daisuke Nanba, Eiji Nishiwaki, Hiroshi Ishiguro, Shigeki Higashiyama, Nariaki Matsuur. PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor. The Journal of biological chemistry. vol 278. issue 46. 2003-12-24. PMID:12952982. |
a disintegrin and metalloprotease 12 (adam12/meltrin alpha) is a key enzyme implicated in the ectodomain shedding of membrane-anchored heparin-binding epidermal growth factor (egf)-like growth factor (prohb-egf)-dependent epidermal growth factor receptor (egfr) transactivation. |
2003-12-24 |
2023-08-12 |
Not clear |
| Güliz Akdas Barkan, Augusto F G Paulin. Are epidermal growth factor and transforming growth factor responsible for pseudoepitheliomatous hyperplasia associated with granular cell tumors? Annals of diagnostic pathology. vol 7. issue 2. 2003-12-15. PMID:12715330. |
we hypothesize that the expression of epidermal growth factor receptor (egfr), epidermal growth factor (egf), and transforming growth factor alpha (tgfalpha) in gct have a role in the development of peh overlying some gct. |
2003-12-15 |
2023-08-12 |
Not clear |
| Timothy A Stewar. Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases. Cytokine & growth factor reviews. vol 14. issue 2. 2003-12-08. PMID:12651225. |
therapeutic antibodies directed against tumor necrosis factor alpha (tnf-alpha) for the treatment of rheumatoid arthritis, and against the human egf receptor-2 (her2) receptor for the treatment of breast cancer have provided significant clinical benefit for the patients. |
2003-12-08 |
2023-08-12 |
human |
| Husam A J Alwan, Everardus J J van Zoelen, Jeroen E M van Leeuwe. Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitination. The Journal of biological chemistry. vol 278. issue 37. 2003-11-12. PMID:12829707. |
studies on the differential routing of internalized epidermal growth factor receptors (egfrs) induced by egf, tgf alpha, and the superagonist egf-tgf alpha chimera e4t suggested a correlation between receptor recycling and their mitogenic potency. |
2003-11-12 |
2023-08-12 |
Not clear |
| Husam A J Alwan, Everardus J J van Zoelen, Jeroen E M van Leeuwe. Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitination. The Journal of biological chemistry. vol 278. issue 37. 2003-11-12. PMID:12829707. |
our results demonstrate that e4t and tgf alpha provoke decreased cbl recruitment, egfr ubiquitination and egfr degradation compared with egf. |
2003-11-12 |
2023-08-12 |
Not clear |
| Lin Guo, Carl J Kozlosky, Lowell H Ericsson, Thomas O Daniel, Douglas P Cerretti, Richard S Johnso. Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor. Journal of the American Society for Mass Spectrometry. vol 14. issue 9. 2003-11-05. PMID:12954170. |
ligand concentrations were varied for epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) as stimuli, and all of the egfr tyrosine sites were consequently found to exhibit increased levels of phosphorylation, although at different rates and to different extents. |
2003-11-05 |
2023-08-12 |
human |
| Nicholas J Kenney, Arthur Bowman, Kenneth S Korach, J Carl Barrett, David S Salomo. Effect of exogenous epidermal-like growth factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse. Breast cancer research and treatment. vol 79. issue 2. 2003-11-04. PMID:12825851. |
the development of the mouse mammary gland requires the interaction between several different ovarian and pituitary hormones such as estrogen, progesterone and prolactin as well as several locally-derived growth factors in the mammary gland such as epidermal growth factor (egf), transforming growth factor alpha (tgfalpha), amphiregulin (ar) and heregulin (hrg). |
2003-11-04 |
2023-08-12 |
mouse |
| S Fintelmann, M Jung, H Weidenbach, A U Steinle, H G Beger, A K Nüssle. [Effect of cellular growth factors on hepatocytes in experimental infection--regulation of NF-kappa B and glutathione homeostasis]. Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress. vol 115. issue Suppl I. 2003-11-03. PMID:14518286. |
our data clearly demonstrate that hepatocellular growth factors such as egf and tgf alpha can increase the gsh contents and the nox production. |
2003-11-03 |
2023-08-12 |
Not clear |
| Claire Glister, Nigel P Groome, Philip G Knigh. Oocyte-mediated suppression of follicle-stimulating hormone- and insulin-like growth factor-induced secretion of steroids and inhibin-related proteins by bovine granulosa cells in vitro: possible role of transforming growth factor alpha. Biology of reproduction. vol 68. issue 3. 2003-10-21. PMID:12604623. |
given the similarity of these oocyte-mediated actions to those we observed previously following epidermal growth factor (egf) treatment, we used immunocytochemistry to determine whether bovine oocytes express egf or transforming growth factor (tgf) alpha. |
2003-10-21 |
2023-08-12 |
cattle |
| Sarah Kraus, Outhiriaradjou Benard, Zvi Naor, Rony Sege. c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells. The Journal of biological chemistry. vol 278. issue 35. 2003-10-02. PMID:12750372. |
here we expressed gnrhr in cos7 cells and found that gnrhr transmits its signals to mapks mainly via g alpha i, egf receptor without the involvement of hb-egf, and c-src, but independently of pkcs. |
2003-10-02 |
2023-08-12 |
human |
| Luisa Salvatori, Pierlorenzo Pallante, Linda Ravenna, Patrizia Chinzari, Luigi Frati, Matteo A Russo, Elisa Petrangel. Oestrogens and selective oestrogen receptor (ER) modulators regulate EGF receptor gene expression through human ER alpha and beta subtypes via an Sp1 site. Oncogene. vol 22. issue 31. 2003-09-10. PMID:12894229. |
oestrogens and selective oestrogen receptor (er) modulators regulate egf receptor gene expression through human er alpha and beta subtypes via an sp1 site. |
2003-09-10 |
2023-08-12 |
human |
| Stavroula Assimacopoulos, Elizabeth A Grove, Clifton W Ragsdal. Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 16. 2003-09-03. PMID:12878679. |
the cortical antihem is identified by gene expression for three epidermal growth factor (egf) family members, tgf(alpha), neuregulin 1, and neuregulin 3, as well as two other signaling molecules, fgf7 and the secreted wnt antagonist sfrp2. |
2003-09-03 |
2023-08-12 |
mouse |
| Teresa A Zimmers, Iain H McKillop, Robert H Pierce, Joo-Yeon Yoo, Leonidas G Koniari. Massive liver growth in mice induced by systemic interleukin 6 administration. Hepatology (Baltimore, Md.). vol 38. issue 2. 2003-08-29. PMID:12883476. |
hgf receptor and transforming growth factor alpha (tgf-alpha)/epidermal growth factor (egf) receptor activation were decreased in hypertrophied livers, suggesting that il-6-induced liver growth was independent of these known hepatocyte mitotic pathways. |
2003-08-29 |
2023-08-12 |
mouse |
| Zheng Wang, Guliang Wang, Jun Yang, Lei Guo, Yingnian Y. Activation of protein kinase A and clustering of cell surface receptors by N-methyl-N'-nitro-N-nitrosoguanidine are independent of genomic DNA damage. Mutation research. vol 528. issue 1-2. 2003-08-25. PMID:12873720. |
and similar to the cell response caused by uv, the clustering of cell surface receptors of epidermal growth factor (egf) and tumor necrosis factor alpha (tnfalpha) was also observed in cells exposed to mnng. |
2003-08-25 |
2023-08-12 |
Not clear |
| Robert N Jorissen, Herbert R Treutlein, V Chandana Epa, Antony W Burges. Modeling the epidermal growth factor -- epidermal growth factor receptor l2 domain interaction: implications for the ligand binding process. Journal of biomolecular structure & dynamics. vol 19. issue 6. 2003-08-19. PMID:12023799. |
signaling from the epidermal growth factor (egf) receptor is triggered by the binding of ligands such as egf or transforming growth factor alpha (tgf-alpha) and subsequent receptor dimerization. |
2003-08-19 |
2023-08-12 |
Not clear |
| Sylvie Rodrigues, Samir Attoub, Quang-Dé Nguyen, Erik Bruyneel, Christelle M Rodrigue, Bruce R Westley, Felicity E B May, Lars Thim, Marc Mareel, Shahin Emami, Christian Gespac. Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells. Oncogene. vol 22. issue 29. 2003-08-19. PMID:12881705. |
similarly, egfr-tk inhibition by zd1839 reversed the invasive phenotype promoted by the constitutively activated form of the egfr (egfrviii) and the egfr agonists transforming growth factor alpha (tgfalpha), amphiregulin and egf. |
2003-08-19 |
2023-08-12 |
human |
| Paul V Beum, Dhundy R Bastola, Pi-Wan Chen. Mucin biosynthesis: epidermal growth factor downregulates core 2 enzymes in a human airway adenocarcinoma cell line. American journal of respiratory cell and molecular biology. vol 29. issue 1. 2003-08-05. PMID:12600830. |
transforming growth factor alpha mimicked the effect of egf on c2gnt, implicating the egf receptor (egf-r) in c2gnt suppression, and the egf-r tyrosine kinase inhibitor ag1478 blocked c2gnt suppression, confirming the role of egf-r in the inhibition of c2gnt expression. |
2003-08-05 |
2023-08-12 |
human |
| R E Robert. Alpha 2 adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein: role of phosphatidylinositol 3-kinase and EGF receptor transactivation. British journal of pharmacology. vol 138. issue 1. 2003-07-15. PMID:12522079. |
alpha 2 adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein: role of phosphatidylinositol 3-kinase and egf receptor transactivation. |
2003-07-15 |
2023-08-12 |
Not clear |