| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R C Fowkes, J Burch, J M Burri. Stimulation of extracellular signal-regulated kinase by pituitary adenylate cyclase-activating polypeptide in alpha T3-1 gonadotrophs. The Journal of endocrinology. vol 171. issue 3. 2002-01-22. PMID:11739023. |
treatment of alpha t3-1 cells with pacap (100 nm) or epidermal growth factor (egf, 10 nm) for 5 min significantly stimulated extracellular signal-regulated kinase activity (erk, a component of the mapk pathway) as determined by an immunocomplex assay. |
2002-01-22 |
2023-08-12 |
human |
| V Fanos, C Pizzini, M Mussap, D Benini, M Pleba. Urinary epidermal growth factor in different renal conditions in children. Renal failure. vol 23. issue 3-4. 2001-12-28. PMID:11499574. |
several studies have demonstrated the important role of growth factors, particularly epidermal growth factor (egf) and transforming growth factor alpha (tgfalpha), in cellular growth after renal damage. |
2001-12-28 |
2023-08-12 |
Not clear |
| K Wollenhaupt, A Kettler, K P Brüssow, F Schneider, W Kanitz, R Einspanie. Regulation of the expression and bioactivation of the epidermal growth factor receptor system by estradiol in pig oviduct and endometrium. Reproduction, fertility, and development. vol 13. issue 2-3. 2001-12-07. PMID:11720134. |
transcript levels of egf and transforming growth factor alpha remained unchanged in both the oviduct and endometrium during treatment. |
2001-12-07 |
2023-08-12 |
Not clear |
| F Hsiung, E R Griffis, A Pickup, M A Powers, K Mose. Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star. Mechanisms of development. vol 107. issue 1-2. 2001-12-04. PMID:11520660. |
drosophila spitz is a homolog of transforming growth factor alpha (tgf-alpha) and is an activating ligand for the egf receptor (egfr). |
2001-12-04 |
2023-08-12 |
drosophila_melanogaster |
| K Aoyagi, K Kohfuji, S Yano, N Murakami, M Miyagi, J Takeda, K Shirouz. Evaluation of the epidermal growth factor receptor (EGFR) and c-erbB-2 in superspreading-type and penetrating-type gastric carcinoma. The Kurume medical journal. vol 48. issue 3. 2001-12-04. PMID:11680933. |
the expression of epidermal growth factor (egf), epidermal growth factor receptor (egfr), transforming growth factor alpha (tgf alpha), and of c-erbb-2 was immunohistochemically investigated in resected gastric carcinoma (in 39 cases of superspreading type and in 11 cases of penetrating type), to understand the differential biological features of these two types of gastric carcinoma. |
2001-12-04 |
2023-08-12 |
Not clear |
| T C Elleman, T Domagala, N M McKern, M Nerrie, B Lönnqvist, T E Adams, J Lewis, G O Lovrecz, P A Hoyne, K M Richards, G J Howlett, J Rothacker, R N Jorissen, M Lou, T P Garrett, A W Burgess, E C Nice, C W War. Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain. Biochemistry. vol 40. issue 30. 2001-10-11. PMID:11467954. |
murine and human epidermal growth factor receptors (egfrs) bind human egf (hegf), mouse egf (megf), and human transforming growth factor alpha (htgf-alpha) with high affinity despite the significant differences in the amino acid sequences of the ligands and the receptors. |
2001-10-11 |
2023-08-12 |
mouse |
| T M Thway, M W Wolf. Epidermal growth factor regulation of equine glycoprotein hormone alpha subunit expression in trophoblast cells. Biology of reproduction. vol 65. issue 1. 2001-10-04. PMID:11420240. |
in the present study, we investigated the regulation of the equine alpha subunit gene by egf in trophoblasts. |
2001-10-04 |
2023-08-12 |
human |
| S Boillée, J Cadusseau, M Coulpier, G Grannec, M P Junie. Transforming growth factor alpha: a promoter of motoneuron survival of potential biological relevance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 18. 2001-10-04. PMID:11549718. |
expression of transforming growth factor alpha (tgfalpha), a member of the epidermal growth factor (egf) family, is a general response of adult murine motoneurons to genetic and experimental lesions, tgfalpha appearing as an inducer of astrogliosis in these situations. |
2001-10-04 |
2023-08-12 |
mouse |
| B Kullenberg, C Jansen, N Fredäng, B Ohlsson, J Axelso. Transforming growth factor alpha (TGF-alpha) increases cell number in a human pancreatic cancer cell line but not in normal mouse pancreas. International journal of pancreatology : official journal of the International Association of Pancreatology. vol 28. issue 3. 2001-09-27. PMID:11373057. |
human pancreatic cancer overexpresses the egf receptor, and the ligands egf and transforming growth factor alpha (tgf-alpha). |
2001-09-27 |
2023-08-12 |
mouse |
| M Roh, A J Paterson, S L Asa, E Chin, J E Kudlo. Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice. Molecular endocrinology (Baltimore, Md.). vol 15. issue 4. 2001-09-20. PMID:11266511. |
the epidermal growth factor receptor (egfr) and its ligands egf and transforming growth factor-alpha (tgf alpha) are expressed in the anterior pituitary, and overexpression of tgf alpha in the lactotrope cells of the pituitary gland in transgenic mice results in lactotrope hyperplasia and adenomata, suggesting a role for egfr signaling in pituitary cell proliferation. |
2001-09-20 |
2023-08-12 |
mouse |
| P A Klekotka, S A Santoro, H Wang, M M Zutte. Specific residues within the alpha 2 integrin subunit cytoplasmic domain regulate migration and cell cycle progression via distinct MAPK pathways. The Journal of biological chemistry. vol 276. issue 34. 2001-09-20. PMID:11418614. |
the alpha(2) integrin subunit cytoplasmic domain is necessary for epidermal growth factor (egf)-stimulated chemotactic migration and insulin-dependent entry into s-phase of mammary epithelial cells adherent to type i collagen. |
2001-09-20 |
2023-08-12 |
Not clear |
| D Bello-DeOcampo, H K Kleinman, M M Webbe. The role of alpha 6 beta 1 integrin and EGF in normal and malignant acinar morphogenesis of human prostatic epithelial cells. Mutation research. vol 480-481. 2001-09-20. PMID:11506815. |
the role of alpha 6 beta 1 integrin and egf in normal and malignant acinar morphogenesis of human prostatic epithelial cells. |
2001-09-20 |
2023-08-12 |
human |
| J Albanell, J Codony-Servat, F Rojo, J M Del Campo, S Sauleda, J Anido, G Raspall, J Giralt, J Roselló, R I Nicholson, J Mendelsohn, J Baselg. Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments. Cancer research. vol 61. issue 17. 2001-09-13. PMID:11522647. |
the expression of epidermal growth factor (egf) receptor (p = 0.037), transforming growth factor alpha (tgf-alpha; p < 0.001), and her2 (p = 0.066; positive trend) correlated with activation of erk1/2. |
2001-09-13 |
2023-08-12 |
Not clear |
| V B Thøgersen, B S Sørensen, S S Poulsen, T F Orntoft, H Wolf, E Nex. A subclass of HER1 ligands are prognostic markers for survival in bladder cancer patients. Cancer research. vol 61. issue 16. 2001-09-06. PMID:11507076. |
the mrna content for six ligands [egf, transforming growth factor alpha (tgf-alpha), amphiregulin (ar), betacellulin (betacl), heparin-binding egf-like growth factor (hb-egf), epiregulin (epi)] and two receptors [egf receptor i human egf receptor (her1) and 2 (her2)] was examined by a newly developed quantitative reverse transcription-pcr method. |
2001-09-06 |
2023-08-12 |
human |
| T Klonisch, P Wolf, S Hombach-Klonisch, S Vogt, A Kuechenhoff, F Tetens, B Fische. Epidermal growth factor-like ligands and erbB genes in the peri-implantation rabbit uterus and blastocyst. Biology of reproduction. vol 64. issue 6. 2001-08-02. PMID:11369616. |
molecular cloning of the partial cdna coding sequences of the four erbb receptors and the epidermal growth factor (egf)-like ligands egf, transforming growth factor alpha (tgf), and heparin-binding egf (hb-egf) has provided the basis for a comprehensive analysis of the spatiotemporal expression pattern of the egf receptor/ligand system during the peri-implantation period in the rabbit. |
2001-08-02 |
2023-08-12 |
rabbit |
| C Borel, O Schorr, I Durand, F Zoulim, A Kay, C Trepo, O Hant. Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression. Hepatology (Baltimore, Md.). vol 34. issue 1. 2001-07-26. PMID:11431748. |
cell cycle progression of fetal hepatocytes can be triggered by stimulation with epidermal growth factor (egf), hepatocyte growth factor (hgf), and tumor growth factor alpha (tgf-alpha). |
2001-07-26 |
2023-08-12 |
Not clear |
| M Matsumoto, M Imagawa, Y Aok. Epidermal growth factor regulation of glutathione S-transferase gene expression in the rat is mediated by class Pi glutathione S-transferase enhancer I. The Biochemical journal. vol 349. issue Pt 1. 2001-07-19. PMID:10861232. |
using chloramphenicol acetyltransferase assays we showed that epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), and 3,3',4,4',5-pentachlorobiphenyl (pencb) induce class pi glutathione s-transferase (gstp1) in primary cultured rat liver parenchymal cells. |
2001-07-19 |
2023-08-12 |
rat |
| M Matsumoto, M Imagawa, Y Aok. Epidermal growth factor regulation of glutathione S-transferase gene expression in the rat is mediated by class Pi glutathione S-transferase enhancer I. The Biochemical journal. vol 349. issue Pt 1. 2001-07-19. PMID:10861232. |
gstp1 enhancer i (gpei), which is required for the stimulation of gstp1 expression by pencb, also mediates egf and tgf alpha stimulation of gstp1 gene expression. |
2001-07-19 |
2023-08-12 |
rat |
| M Matsumoto, M Imagawa, Y Aok. Epidermal growth factor regulation of glutathione S-transferase gene expression in the rat is mediated by class Pi glutathione S-transferase enhancer I. The Biochemical journal. vol 349. issue Pt 1. 2001-07-19. PMID:10861232. |
our observations suggest that egf and tgf alpha induce gstp1 by the same signal transduction pathway as pencb. |
2001-07-19 |
2023-08-12 |
rat |
| M L van de Poll, W van Rotterdam, M M Gadellaa, C Stortelers, M J van Vugt, E J van Zoele. Non-linear antigenic regions in epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) studied by EGF-TGF alpha chimaeras. The Biochemical journal. vol 349. issue Pt 1. 2001-07-19. PMID:10861238. |
non-linear antigenic regions in epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) studied by egf-tgf alpha chimaeras. |
2001-07-19 |
2023-08-12 |
human |