| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J S Condeelis, J B Wyckoff, M Bailly, R Pestell, D Lawrence, J Backer, J E Segal. Lamellipodia in invasion. Seminars in cancer biology. vol 11. issue 2. 2001-07-12. PMID:11322831. |
evaluation of some of the downstream events in lamellipod extension indicates: (1) plasma membrane distribution of the egf receptor is uniform but internalized receptor accumulates on the side of the cell closest to the source of egf; (2) the alpha p110 isoform of pi-3 kinase is required; and (3) protrusion of the lamellipod relies upon the combined actions of the arp2/3 complex and cofilin for generation of filamentous actin. |
2001-07-12 |
2023-08-12 |
Not clear |
| b' K P Vasilenko, P S Grudinkin, A M Arnautov, E B Burova, N N Nikol\'ski\\xc4\\xa. [Dynamics of the interaction of Stat1 transcription factor with the internalized EGF receptor and karyopherins alpha in response to stimulation of cells with epidermal growth factor]. Tsitologiia. vol 43. issue 2. 2001-07-12. PMID:11347476.' |
[dynamics of the interaction of stat1 transcription factor with the internalized egf receptor and karyopherins alpha in response to stimulation of cells with epidermal growth factor]. |
2001-07-12 |
2023-08-12 |
Not clear |
| L Strachan, J G Murison, R L Prestidge, M A Sleeman, J D Watson, K D Kumbl. Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily. The Journal of biological chemistry. vol 276. issue 21. 2001-07-05. PMID:11278323. |
recombinant epigen was synthesized in escherichia coli and refolded, and its biological activity was compared with that of egf and transforming growth factor alpha in several assays. |
2001-07-05 |
2023-08-12 |
mouse |
| S E Hoegy, H R Oh, M L Corcoran, W G Stetler-Stevenso. Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition. The Journal of biological chemistry. vol 276. issue 5. 2001-06-21. PMID:11042184. |
timp-2 neither altered the release of transforming growth factor alpha from the cell surface, nor epidermal growth factor (egf) binding to the cognate receptor, egfr. |
2001-06-21 |
2023-08-12 |
Not clear |
| C Gründker, P Völker, G Emon. Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase. Endocrinology. vol 142. issue 6. 2001-06-21. PMID:11356684. |
inhibition of epidermal growth factor (egf)-induced c-fos expression by lhrh, however, was mediated through pertussis toxin (ptx)-sensitive g protein alpha(i). |
2001-06-21 |
2023-08-12 |
human |
| N Pouliot, E C Nice, A W Burges. Laminin-10 mediates basal and EGF-stimulated motility of human colon carcinoma cells via alpha(3)beta(1) and alpha(6)beta(4) integrins. Experimental cell research. vol 266. issue 1. 2001-06-14. PMID:11339819. |
the migration response to laminin-10 is increased upon stimulation of the cells with egf and correlates with the up-regulation of alpha(6)beta(4) integrin expression as measured by analysis of triton x-100-soluble cellular extracts. |
2001-06-14 |
2023-08-12 |
human |
| N Pouliot, E C Nice, A W Burges. Laminin-10 mediates basal and EGF-stimulated motility of human colon carcinoma cells via alpha(3)beta(1) and alpha(6)beta(4) integrins. Experimental cell research. vol 266. issue 1. 2001-06-14. PMID:11339819. |
taken together, these results support the cooperative role of egf receptor and laminin-10 on colon cancer cell motility and suggest a critical role for both the alpha(3)beta(1) and the alpha(6)beta(4) integrins in this process. |
2001-06-14 |
2023-08-12 |
human |
| P Hoffmann, M Reinshagen, J M Zeeh, J Lakshmanan, V S Wu, H Goebell, G Gerken, V E Eysselei. Increased expression of epidermal growth factor-receptor in an experimental model of colitis in rats. Scandinavian journal of gastroenterology. vol 35. issue 11. 2001-05-10. PMID:11145289. |
we have shown previously that exogenously applied egf protects colonic mucosa against injury in an experimental model of colitis in rats and that the endogenously expressed ligands for the egf-receptor are predominantly transforming growth factor alpha precursors. |
2001-05-10 |
2023-08-12 |
rat |
| P A Klekotka, S A Santoro, M M Zutte. alpha 2 integrin subunit cytoplasmic domain-dependent cellular migration requires p38 MAPK. The Journal of biological chemistry. vol 276. issue 12. 2001-05-03. PMID:11121402. |
the alpha(2) integrin subunit cytoplasmic domain uniquely supported epidermal growth factor (egf)-stimulated migration on type i collagen. |
2001-05-03 |
2023-08-12 |
Not clear |
| J H Bennett, D H Carter, A L Alavi, J N Beresford, S Wals. Patterns of integrin expression in a human mandibular explant model of osteoblast differentiation. Archives of oral biology. vol 46. issue 3. 2001-04-26. PMID:11165569. |
in the presence of egf there was increased alpha(2) expression. |
2001-04-26 |
2023-08-12 |
human |
| B P Barna, R Mattera, B S Jacobs, J Drazba, M E Estes, R A Prayson, G H Barnet. Epidermal growth factor regulates astrocyte expression of the interleukin-4 receptor via a MAPK-independent pathway. Cellular immunology. vol 208. issue 1. 2001-04-26. PMID:11277615. |
we hypothesized that epidermal growth factor (egf) and il-4, agents that profoundly affect astrocyte proliferation, might also alter il-4r alpha expression. |
2001-04-26 |
2023-08-12 |
human |
| B P Barna, R Mattera, B S Jacobs, J Drazba, M E Estes, R A Prayson, G H Barnet. Epidermal growth factor regulates astrocyte expression of the interleukin-4 receptor via a MAPK-independent pathway. Cellular immunology. vol 208. issue 1. 2001-04-26. PMID:11277615. |
exposure to egf for 24 h enhanced il-4r alpha mrna levels; in contrast, il-4 yielded no increase. |
2001-04-26 |
2023-08-12 |
human |
| B P Barna, R Mattera, B S Jacobs, J Drazba, M E Estes, R A Prayson, G H Barnet. Epidermal growth factor regulates astrocyte expression of the interleukin-4 receptor via a MAPK-independent pathway. Cellular immunology. vol 208. issue 1. 2001-04-26. PMID:11277615. |
immunoblotting demonstrated that egf but not il-4 increased astrocyte il-4r alpha protein after 2--4 days of exposure. |
2001-04-26 |
2023-08-12 |
human |
| B P Barna, R Mattera, B S Jacobs, J Drazba, M E Estes, R A Prayson, G H Barnet. Epidermal growth factor regulates astrocyte expression of the interleukin-4 receptor via a MAPK-independent pathway. Cellular immunology. vol 208. issue 1. 2001-04-26. PMID:11277615. |
pd98059 also blocked egf-stimulated dna synthesis but not il-4r alpha mrna levels, while antibody to the egf receptor (erbb1) blocked both egf effects. |
2001-04-26 |
2023-08-12 |
human |
| B P Barna, R Mattera, B S Jacobs, J Drazba, M E Estes, R A Prayson, G H Barnet. Epidermal growth factor regulates astrocyte expression of the interleukin-4 receptor via a MAPK-independent pathway. Cellular immunology. vol 208. issue 1. 2001-04-26. PMID:11277615. |
data suggest that astrocyte il-4r alpha expression is upregulated by egf but not by il-4 in an egf-receptor-dependent manner and that mechanisms are independent of mapk activation. |
2001-04-26 |
2023-08-12 |
human |
| J M Harper, P J Butter. Effects of EGF receptor ligands on fetal ovine myoblasts. Domestic animal endocrinology. vol 20. issue 1. 2001-04-19. PMID:11164331. |
competitive binding studies in mixed secondary cultures showed that egf had the highest affinity for the fetal ovine receptor, followed by hb-egf and transforming growth factor alpha (tgf-alpha). |
2001-04-19 |
2023-08-12 |
human |
| S C Zhang, C Lundberg, D Lipsitz, L T O'Connor, I D Dunca. Generation of oligodendroglial progenitors from neural stem cells. Journal of neurocytology. vol 27. issue 7. 2001-04-12. PMID:11246488. |
rt-pcr analysis indicated that the oligosphere cells expressed mrnas of platelet-derived growth factor alpha receptor in addition to fibroblast growth factor receptor but not egf receptor; the latter two receptor mrnas were expressed by neurosphere cells. |
2001-04-12 |
2023-08-12 |
rat |
| Y Yamanaka, K Hayashi, T Komurasaki, S Morimoto, T Ogihara, K Sobu. EGF family ligand-dependent phenotypic modulation of smooth muscle cells through EGF receptor. Biochemical and biophysical research communications. vol 281. issue 2. 2001-03-29. PMID:11181057. |
among four egf-receptor (egfr) family members, the egfr was solely activated by egf, heparin-binding egf (hb-egf), transforming growth factor alpha (tgf alpha), epiregulin (er), and betacellulin (btc), resulting in induction of phenotypic modulation of smcs. |
2001-03-29 |
2023-08-12 |
Not clear |
| C Deachapunya, S M O'Grad. Epidermal growth factor regulates the transition from basal sodium absorption to anion secretion in cultured endometrial epithelial cells. Journal of cellular physiology. vol 186. issue 2. 2001-03-22. PMID:11169461. |
the objective of this study was to investigate acute and long-term effects of epidermal growth factor (egf) and transforming growth factor alpha (tgfalpha) on basal ion transport activity of glandular endometrial epithelial cells in primary culture. |
2001-03-22 |
2023-08-12 |
Not clear |
| J J Scarisbrick, E Calonje, G Orchard, F J Child, R Russell-Jone. Pseudocarcinomatous change in lymphomatoid papulosis and primary cutaneous CD30+ lymphoma: a clinicopathologic and immunohistochemical study of 6 patients. Journal of the American Academy of Dermatology. vol 44. issue 2. 2001-03-15. PMID:11174381. |
immunohistochemical staining for epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) showed similar expression in lesional and perilesional skin. |
2001-03-15 |
2023-08-12 |
Not clear |