| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Chevalier, N Macdonald, R A Robert. Induction of DNA replication by peroxisome proliferators is independent of both tumour necrosis factor (alpha) priming and EGF-receptor tyrosine kinase activity. Journal of cell science. vol 112 ( Pt 24). 2000-04-24. PMID:10574725. |
therefore, although tnf(alpha) can act as a priming factor for growth factors such as egf, nafenopin does not appear to act via this mechanism. |
2000-04-24 |
2023-08-12 |
rat |
| R N Jorissen, V C Epa, H R Treutlein, T P Garrett, C W Ward, A W Burges. Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor. Protein science : a publication of the Protein Society. vol 9. issue 2. 2000-04-21. PMID:10716183. |
the epidermal growth factor (egf) receptor is a tyrosine kinase that mediates the biological effects of ligands such as egf and transforming growth factor alpha. |
2000-04-21 |
2023-08-12 |
Not clear |
| N Faust. Liver regeneration. Journal of hepatology. vol 32. issue 1 Suppl. 2000-04-11. PMID:10728791. |
hepatocytes need to be primed before they can fully respond to the growth factors hgf (hepatocyte growth factor), tgfalpha (transforming growth factor alpha), and egf (epidermal growth factor) in vitro. |
2000-04-11 |
2023-08-12 |
mouse |
| J Morris-Wiman, R Sego, L Brinkley, C Dolc. The effects of sialoadenectomy and exogenous EGF on taste bud morphology and maintenance. Chemical senses. vol 25. issue 1. 2000-04-07. PMID:10667989. |
tongues were removed and histologically examined for the presence and morphology of taste buds on fungiform and circumvallate papillae, or immunostained for the presence of egf, tgfalpha (transforming growth factor alpha) and egfr (egf receptor). |
2000-04-07 |
2023-08-12 |
rat |
| B Montaner, R Pérez-Tomá. Epidermal growth factor receptor (EGF-R) localization in the apical membrane of the enterocytes of rat duodenum. Cell biology international. vol 23. issue 7. 2000-04-04. PMID:10728784. |
some growth factors, such as epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha), bind to epidermal growth factor receptor (egf-r) to exert these functions. |
2000-04-04 |
2023-08-12 |
rat |
| H Zhong, K P Minnema. Activation of tyrosine kinases by alpha1A-adrenergic and growth factor receptors in transfected PC12 cells. The Biochemical journal. vol 344 Pt 3. 2000-03-17. PMID:10585878. |
norepinephrine (ne) (noradrenaline), epidermal growth factor (egf) and nerve growth factor (ngf) caused different patterns of tyrosine phosphorylation in pc12 cells stably expressing alpha(1a)-ars. |
2000-03-17 |
2023-08-12 |
Not clear |
| K P McNatty, D A Heath, T Lundy, A E Fidler, L Quirke, A O'Connell, P Smith, N Groome, D J Tisdal. Control of early ovarian follicular development. Journal of reproduction and fertility. Supplement. vol 54. 2000-03-13. PMID:10692841. |
in sheep, cows and pigs, numerous growth factor, growth factor receptor and gonadotrophin receptor mrnas and peptides (for example c-kit, stem cell factor, gdf-9, beta b and beta a activin/inhibin subunit, alpha inhibin subunit, follistatin, fgf-2, egf, egf-r, tgf beta 1,2 and 3 fsh-r and lh-r) are expressed in a phase of growth (for example types 1-5)-specific and cell-specific manner. |
2000-03-13 |
2023-08-12 |
cattle |
| L W Reneker, D W Silversides, L Xu, P A Overbee. Formation of corneal endothelium is essential for anterior segment development - a transgenic mouse model of anterior segment dysgenesis. Development (Cambridge, England). vol 127. issue 3. 2000-03-09. PMID:10631174. |
we have generated transgenic mice that express either transforming growth factor (alpha) (tgf(alpha)) or epidermal growth factor (egf) in the ocular lens using the mouse (alpha)a-crystallin promoter. |
2000-03-09 |
2023-08-12 |
mouse |
| N Desai, J Lawson, J Goldfar. Assessment of growth factor effects on post-thaw development of cryopreserved mouse morulae to the blastocyst stage. Human reproduction (Oxford, England). vol 15. issue 2. 2000-03-07. PMID:10655314. |
thawed morulae (n = 206) were randomly distributed between 10 treatment groups: medium alone control (ct), vero (vr) cells, leukaemia inhibitory factor (1 ng/ml), interleukin-6 (1 ng/ml), transforming growth factor (tgf) alpha (2 ng/ml), epidermal growth factor (egf) (4 ng/ml), platelet-derived growth factor (1 ng/ml), insulin-like growth factor (igf)-i (30 ng/ml), igf-ii (1 ng/ml) and tgfbeta (2 ng/ml). |
2000-03-07 |
2023-08-12 |
mouse |
| S Werner, B Mun. Suppression of keratin 15 expression by transforming growth factor beta in vitro and by cutaneous injury in vivo. Experimental cell research. vol 254. issue 1. 2000-02-24. PMID:10623468. |
expression of k15 was also suppressed by tumor necrosis factor alpha (tnf-alpha) and to a lesser extent by epidermal growth factor (egf) and keratinocyte growth factor (kgf). |
2000-02-24 |
2023-08-12 |
Not clear |
| R A Roberts, N H James, S C Cosulic. The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis. Hepatology (Baltimore, Md.). vol 31. issue 2. 2000-02-24. PMID:10655266. |
in this study, we have investigated the role of signaling pathways activated by tumor necrosis factor alpha (tnf-alpha) and epidermal growth factor (egf) in the regulation of apoptosis induced by transforming growth factor beta(1) (tgf-beta(1)), because this physiological factor is believed to regulate spontaneous apoptosis in the liver. |
2000-02-24 |
2023-08-12 |
rat |
| T Sasanami, M Ikami, M Mor. Involvement of mitogen-activated protein kinase in transforming growth factor alpha-stimulated cell proliferation in the cultured granulosa cells of the Japanese quail. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. vol 124. issue 1. 2000-02-04. PMID:10579644. |
in order to study the involvement of mitogen-activated protein (map) kinase in proliferation of the granulosa cells in avian species, quail granulosa cells were cultured for 66 h with various hormones (follicle stimulating hormone (fsh), lh, progesterone, estradiol-17beta, testosterone), or growth factors (transforming growth factor alpha (tgf alpha), epidermal growth factor (egf), insulin-like growth factor i (igf-i), igf-ii), and the presence of immunodetectable map kinase was examined in the cell lysates. |
2000-02-04 |
2023-08-12 |
Not clear |
| E L Duncan, M A Brown, J Sinsheimer, J Bell, A J Carr, B P Wordsworth, J A Was. Suggestive linkage of the parathyroid receptor type 1 to osteoporosis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 14. issue 12. 2000-01-27. PMID:10620056. |
the candidate genes studied were the androgen receptor, type i collagen a1 (colia1), colia2, coliia1, vitamin d receptor (vdr), colony-stimulating factor 1, calcium-sensing receptor, epidermal growth factor (egf), estrogen receptor 1 (esr1), fibrillin type 1, insulin-like growth factor 1, interleukin-1 alpha (il-1alpha), interleukin-4 (il-4), interleukin-6 (il-6), interleukin-11 (il-11), osteopontin, parathyroid hormone (pth), pth-related peptide, pth receptor type 1 (pthr1), transforming growth factor-beta 1, and tumor necrosis factors alpha and beta. |
2000-01-27 |
2023-08-12 |
Not clear |
| W Pan, K Vallance, A J Kasti. TGFalpha and the blood-brain barrier: accumulation in cerebral vasculature. Experimental neurology. vol 160. issue 2. 2000-01-14. PMID:10619562. |
transforming growth factor alpha (tgfalpha) is a cytokine that belongs to the epidermal growth factor (egf) family of growth factors. |
2000-01-14 |
2023-08-12 |
Not clear |
| H I Kornblum, S D Zurcher, Z Werb, R Derynck, K B Seroog. Multiple trophic actions of heparin-binding epidermal growth factor (HB-EGF) in the central nervous system. The European journal of neuroscience. vol 11. issue 9. 1999-11-24. PMID:10510187. |
heparin-binding epidermal growth factor (hb-egf) interacts with both egf-r and a related receptor, erbb4, whereas transforming growth factor alpha (tgfalpha) interacts only with egf-r. because of the unique characteristics of hb-egf and the potential utility of egf family members in brain repair, we examine the effects of hb-egf on rat and mouse cns cells in vitro and compare them to those of tgfalpha. |
1999-11-24 |
2023-08-12 |
mouse |
| A Hornia, Z Lu, T Sukezane, M Zhong, T Joseph, P Frankel, D A Foste. Antagonistic effects of protein kinase C alpha and delta on both transformation and phospholipase D activity mediated by the epidermal growth factor receptor. Molecular and cellular biology. vol 19. issue 11. 1999-11-24. PMID:10523655. |
in contrast, the pkc alpha-specific inhibitor go6976 and expression of a dominant negative pkc alpha mutant blocked the transformed phenotype induced by both egf and pkc delta inhibition. |
1999-11-24 |
2023-08-12 |
human |
| I On. [Roles of cytokines in wound healing processes]. Nihon Geka Gakkai zasshi. vol 100. issue 9. 1999-11-12. PMID:10516965. |
cytokines, such as epidermal growth factor (egf), basic fibroblast growth factor (bfgf), transforming growth factor (tgf) alpha 1 and interleukin (il)-6, have been shown to exhibit the particular ability to stimulate keratinocyte proliferation. |
1999-11-12 |
2023-08-12 |
human |
| D Wei, S Ge, Y Che. [Experimental study of temporal expression of endogenous TGF alpha in partial thickness scalded wounds]. Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns. vol 13. issue 5. 1999-10-29. PMID:10452037. |
otherwise, the mrna expression of egf receptor manifests the same change as tgf alpha's. |
1999-10-29 |
2023-08-12 |
Not clear |
| D Wei, S Ge, Y Che. [Experimental study of temporal expression of endogenous TGF alpha in partial thickness scalded wounds]. Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns. vol 13. issue 5. 1999-10-29. PMID:10452037. |
thermal injury can induce endogenous tgf alpha and egf receptor expression, which is well controlled and correlated with the migration and proliferation of keratinocytes. |
1999-10-29 |
2023-08-12 |
Not clear |
| W Müller, W Saeger, L Wellhausen, K M Derwahl, C Hamacher, D K Lüdeck. Markers of function and proliferation in non-invasive and invasive bi- and plurihormonal adenomas of patients with acromegaly: an immunohistochemical study. Pathology, research and practice. vol 195. issue 9. 1999-10-28. PMID:10507079. |
twenty-seven plurihormonal and 21 growth hormone- prolactin- (gh- prl-) mixed cell adenomas obtained from patients with acromegaly undergoing transnasal-transsphenoidal surgery were investigated immunohistochemically for expression of epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), insulin-like growth factor-1 (igf-1), estrogen receptor-related protein (errp), multidrug resistance marker (mdrm), protein kinase c (pkc), gs alpha,. |
1999-10-28 |
2023-08-12 |
Not clear |