Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A De Luca, A Casamassimi, M P Selvam, S Losito, F Ciardiello, S Agrawal, D S Salomon, N Normann. EGF-related peptides are involved in the proliferation and survival of MDA-MB-468 human breast carcinoma cells. International journal of cancer. vol 80. issue 4. 1999-02-16. PMID:9935161. |
a majority of human breast carcinomas co-express the epidermal growth factor (egf)-like peptides cripto (cr), amphiregulin (ar) and transforming growth factor alpha (tgf-alpha). |
1999-02-16 |
2023-08-12 |
human |
J T Colston, J J Valdes, J P Chamber. Ca2+ channel alpha 1-subunit transcripts are differentially expressed in rat pheochromocytoma (PC12) cells following nerve growth factor treatment. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 16. issue 5. 1999-02-11. PMID:9829174. |
in contrast to ngf, bfgf and egf treatment had no inhibitory effect on l-type (alpha 1c and alpha 1d) channel transcript levels after 3 days. |
1999-02-11 |
2023-08-12 |
rat |
J T Colston, J J Valdes, J P Chamber. Ca2+ channel alpha 1-subunit transcripts are differentially expressed in rat pheochromocytoma (PC12) cells following nerve growth factor treatment. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 16. issue 5. 1999-02-11. PMID:9829174. |
like ngf, egf treatment had no statistically significant effect upon p-type (alpha 1a) transcript levels but increased in a biphasic manner following bfgf treatment. |
1999-02-11 |
2023-08-12 |
rat |
J T Colston, J J Valdes, J P Chamber. Ca2+ channel alpha 1-subunit transcripts are differentially expressed in rat pheochromocytoma (PC12) cells following nerve growth factor treatment. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 16. issue 5. 1999-02-11. PMID:9829174. |
presynaptic-associated alpha 1b (n-type) ca2+ channel transcripts were observed decreased following egf treatment (2 days) while l-type alpha 1c transcripts decreased after 7 days (p value < 0.01). |
1999-02-11 |
2023-08-12 |
rat |
A Kliem, F Tetens, T Klonisch, M Grealy, B Fische. Epidermal growth factor receptor and ligands in elongating bovine blastocysts. Molecular reproduction and development. vol 51. issue 4. 1999-02-05. PMID:9820199. |
the epidermal growth factor receptor (egf-r) and its ligands are potential components of the embryo-maternal cross-talk: employing rt-pcr, in situ hybridization, and immunohistochemistry, we investigated on mrna and protein level the expression of egf-r, epidermal growth factor (egf), transforming growth factor alpha (tgf-alpha), and heparin-binding egf-like growth factor (hb-egf) in spherical and elongating bovine blastocysts between day 13 and day 16 of gestation, and in endometrium at day 13 of gestation. |
1999-02-05 |
2023-08-12 |
cattle |
R Halse, J J Rochford, J G McCormack, J R Vandenheede, B A Hemmings, S J Yeama. Control of glycogen synthesis in cultured human muscle cells. The Journal of biological chemistry. vol 274. issue 2. 1999-02-05. PMID:9873015. |
egf also caused inhibition of glycogen synthase kinase 3 (gsk-3) and activation of the alpha isoform of protein kinase b (pkb) with the time-course and magnitude of its effects being similar to those induced by insulin. |
1999-02-05 |
2023-08-12 |
human |
J T Hong, Y P Yu. Effects of the peroxisome proliferator ciprofibrate and prostaglandin F2 alpha combination treatment on second messengers in cultured rat hepatocytes. Archives of pharmacal research. vol 21. issue 2. 1999-02-04. PMID:9875418. |
the combination of ciprofibrate and pgf2 alpha also significantly increased egf, transforming growth factor-alpha (tgf-alpha) and hepatic growth factor (hgf)-induced particulate pkc activity. |
1999-02-04 |
2023-08-12 |
rat |
M Broecker, J Hammer, M Derwah. Excessive activation of tyrosine kinases leads to inhibition of proliferation in a thyroid carcinoma cell line. Life sciences. vol 63. issue 26. 1999-01-14. PMID:9877227. |
these cells synthesize epidermal growth factor (egf) receptors and platelet-derived growth factor beta (pdgf beta) receptors and in addition transforming growth factor alpha (tgf alpha), pdgf-a and pdgf-b chains, respectively. |
1999-01-14 |
2023-08-12 |
Not clear |
M Broecker, J Hammer, M Derwah. Excessive activation of tyrosine kinases leads to inhibition of proliferation in a thyroid carcinoma cell line. Life sciences. vol 63. issue 26. 1999-01-14. PMID:9877227. |
we conclude that growth of htc-tshr thyroid carcinoma cells is influenced by two autocrine loops between tgf alpha and egf receptors and between pdgf-b and pdgf beta receptors. |
1999-01-14 |
2023-08-12 |
Not clear |
A C Ruifrok, M M Weil, K A Mason, H D Thame. Induction of transforming growth factor alpha in irradiated mouse jejunum. International journal of radiation oncology, biology, physics. vol 42. issue 5. 1999-01-07. PMID:9869241. |
to determine the involvement of the mitogenic growth factors transforming growth factor alpha (tgf alpha), epidermal growth factor (egf), and the egf receptor (egf-r) in the proliferative response after irradiation of the mouse jejunum. |
1999-01-07 |
2023-08-12 |
mouse |
B D Abbott, M R Probst, G H Perdew, A R Buckale. AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGF alpha, TGF beta 1, TGF beta 2, and TGF beta 3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Teratology. vol 58. issue 2. 1998-12-30. PMID:9787404. |
protein and mrna for epidermal growth factor (egf), transforming growth factor-alpha (tgf alpha), egf receptor, transforming growth factor-beta 1 (tgf beta 1), tgf beta 2, tgf beta 3, glucocorticoid receptor (gr), the aryl hydrocarbon receptor (ahr), and the ah receptor nuclear translocator (arnt) were localized in gestational days (gd) 49-59 human embryonic secondary palates. |
1998-12-30 |
2023-08-12 |
mouse |
B D Abbott, M R Probst, G H Perdew, A R Buckale. AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGF alpha, TGF beta 1, TGF beta 2, and TGF beta 3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Teratology. vol 58. issue 2. 1998-12-30. PMID:9787404. |
relative to patterns in mouse palatal development, human tissues demonstrated expression of egf at early palatal stages, expression of egf receptor and tgf alpha throughout fusion events, and uniform expression of tgf beta 3 in all epithelial regions without specifically higher levels in the medial cells. |
1998-12-30 |
2023-08-12 |
mouse |
R K McCulloch, C E Walker, A Chakera, J Jazayeri, P J Leedma. Regulation of EGF-receptor expression by EGF and TGF alpha in epidermoid cancer cells is cell type-specific. The international journal of biochemistry & cell biology. vol 30. issue 11. 1998-12-24. PMID:9839451. |
regulation of egf-receptor expression by egf and tgf alpha in epidermoid cancer cells is cell type-specific. |
1998-12-24 |
2023-08-12 |
human |
R K McCulloch, C E Walker, A Chakera, J Jazayeri, P J Leedma. Regulation of EGF-receptor expression by EGF and TGF alpha in epidermoid cancer cells is cell type-specific. The international journal of biochemistry & cell biology. vol 30. issue 11. 1998-12-24. PMID:9839451. |
the epidermal growth factor receptor (egf-r) and its major ligands egf and transforming growth factor alpha (tgf alpha) play an important role in the development of multiple human tumors. |
1998-12-24 |
2023-08-12 |
human |
R K McCulloch, C E Walker, A Chakera, J Jazayeri, P J Leedma. Regulation of EGF-receptor expression by EGF and TGF alpha in epidermoid cancer cells is cell type-specific. The international journal of biochemistry & cell biology. vol 30. issue 11. 1998-12-24. PMID:9839451. |
in kb cells, egf and tgf alpha increased egf-r mrna and protein levels by 2-3 fold over 8 h, associated with a greater than 4-fold stabilization of egf-r mrna half-life. |
1998-12-24 |
2023-08-12 |
human |
R K McCulloch, C E Walker, A Chakera, J Jazayeri, P J Leedma. Regulation of EGF-receptor expression by EGF and TGF alpha in epidermoid cancer cells is cell type-specific. The international journal of biochemistry & cell biology. vol 30. issue 11. 1998-12-24. PMID:9839451. |
egf and tgf alpha also increased transcription of egf-r mrna 2-3-fold in kb cells. |
1998-12-24 |
2023-08-12 |
human |
R K McCulloch, C E Walker, A Chakera, J Jazayeri, P J Leedma. Regulation of EGF-receptor expression by EGF and TGF alpha in epidermoid cancer cells is cell type-specific. The international journal of biochemistry & cell biology. vol 30. issue 11. 1998-12-24. PMID:9839451. |
in contrast, egf and tgf alpha only minimally increased egf-r mrna and protein in a431 cells, without changing egf-r mrna half-life. |
1998-12-24 |
2023-08-12 |
human |
R K McCulloch, C E Walker, A Chakera, J Jazayeri, P J Leedma. Regulation of EGF-receptor expression by EGF and TGF alpha in epidermoid cancer cells is cell type-specific. The international journal of biochemistry & cell biology. vol 30. issue 11. 1998-12-24. PMID:9839451. |
taken together, these results demonstrate that in kb cells egf and tgf alpha upregulate egf-r expression at both transcriptional and post-transcriptional levels. |
1998-12-24 |
2023-08-12 |
human |
H Ernst, P C Konturek, T Brzozowski, H Lochs, E G Hahn, S J Konture. Adaptation of gastric mucosa to stress. Effect of ranitidine. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 49. issue 3. 1998-12-18. PMID:9789793. |
luminal acidity, mean lesion number, histology and cell proliferation (pcna-labeling index) were determined and the expression of egf and tgf alpha was assessed by immunohistochemistry. |
1998-12-18 |
2023-08-12 |
rat |
N Reeka, F D Berg, C Brucke. Presence of transforming growth factor alpha and epidermal growth factor in human ovarian tissue and follicular fluid. Human reproduction (Oxford, England). vol 13. issue 8. 1998-12-17. PMID:9756296. |
we examined the immunohistochemical localization of transforming growth factor alpha (tgf-alpha), epidermal growth factor (egf) and epidermal growth factor receptor (egf-r) in 18 human ovaries. |
1998-12-17 |
2023-08-12 |
human |